As the core driving force leading the new round of technological revolution and industrial transformation,artificial intelligence is profoundly reshaping the higher education ecosystem.Based on the background of artif...As the core driving force leading the new round of technological revolution and industrial transformation,artificial intelligence is profoundly reshaping the higher education ecosystem.Based on the background of artificial intelligence development,this paper expounds the value of AI technology in promoting the innovative development of higher education,explores the specific paths of AI technology empowering the innovative development of higher education from three dimensions of talent training,scientific research,and governance,and puts forward the required guarantee conditions.It aims to promote the in-depth integration of artificial intelligence and higher education,profoundly change the form of higher education,lead higher education towards a more personalized,precise,and intelligent development path,and provide reference for solving a series of problems encountered in the current development of higher education.展开更多
This paper presents an overview of the recent developments in hybrid wind-wave energy.With the focus on floating concepts,the possible configurations introduced in the literature are categorized and depicted,and the m...This paper presents an overview of the recent developments in hybrid wind-wave energy.With the focus on floating concepts,the possible configurations introduced in the literature are categorized and depicted,and the main conclusions obtained from the references are summarized.Moreover,offshore wind and wave resources are discussed in terms of complementarity and supplementarity,offering a new perspective to developing hybrid wind-wave energy systems that look for synergies not limited to maximizing power output.Then,the feasibility of the concepts under development is discussed in detail,with focus on technical feasibility,dynamic feasibility and limitations of the methods employed.The hybrid configurations that surpassed the experimental validation phase are highlighted,and the experimental results are summarized.By compiling more than 40 floating wind turbine concepts,new relations are drawn between power,wind turbine dimensions,platforms’draft and displacement,which are further related to the payload allowance of the units to accommodate wave devices and onboard power take-off systems.Bearing in mind that it is a challenge to model the exact dynamics of hybrid floating wind-wave platforms,this paper elucidates the current research gaps,limitations and future trends in the field.Lastly,based on the overview and topics discussed,several major conclusions are drawn concerning hybrid synergies,dynamics and hydrodynamics of hybrid platforms,feasibility of concepts,among other regards.展开更多
Long-life energy storage batteries are integral to energy storage systems and electric vehicles,with lithium-ion batteries(LIBs)currently being the preferred option for extended usage-life energy storage.To further ex...Long-life energy storage batteries are integral to energy storage systems and electric vehicles,with lithium-ion batteries(LIBs)currently being the preferred option for extended usage-life energy storage.To further extend the life span of LIBs,it is essential to intensify investments in battery design,manufacturing processes,and the advancement of ancillary materials.The pursuit of long durability introduces new challenges for battery energy density.The advent of electrode material offers effective support in enhancing the battery’s long-duration performance.Often underestimated as part of the cathode composition,the binder plays a pivotal role in the longevity and electrochemical performance of the electrode.Maintaining the mechanical integrity of the electrode through judicious binder design is a fundamental requirement for achieving consistent long-life cycles and high energy density.This paper primarily concentrates on the commonly employed cathode systems in lithium-ion batteries,elucidates the significance of binders for both,discusses the application status,strengths,and weaknesses of novel binders,and ultimately puts forth corresponding optimization strategies.It underscores the critical function of binders in enhancing battery performance and advancing the sustainable development of lithium-ion batteries,aiming to offer fresh insights and perspectives for the design of high-performance LIBs.展开更多
Tea plant(Camellia sinensis(L.)O.Kuntze)is a cold-sensitive leaf-harvesting crop whose growth,yield,and processed tea quality are all inhibited by low temperatures.Therefore,identifying the regulatory genes involved i...Tea plant(Camellia sinensis(L.)O.Kuntze)is a cold-sensitive leaf-harvesting crop whose growth,yield,and processed tea quality are all inhibited by low temperatures.Therefore,identifying the regulatory genes involved in tea plant growth and freezing tolerance is crucial for genetic improvement.WRKY transcription factors regulate various plant processes,including growth and development,stress responses,and metabolite biosynthesis.However,the molecular network through which WRKY coordinates these pathways in tea plants remains unclear.In this study,we revealed that CsWRKY57L,a cold-inducible WRKY IIc subfamily member,positively regulated freezing tolerance by directly promoting flavonoid accumulation in tea plants.Transient suppression of CsWRKY57L weakened the freezing tolerance of tea plants by reducing flavonoid content and suppressing the C-repeat-binding factor(CBF)-cold-responsive(COR)gene pathway.In contrast,heterologous overexpression of CsWRKY57L in Arabidopsis had the opposite effect.Additionally,overexpression of CsWRKY57L inhibited reproductive development and accelerated senescence in Arabidopsis.Interaction analysis revealed that CsWRKY57L directly binds to the promoters of CsSWEET1a,CsSWEET15,and AtSWEET15,which encode sugar transporters essential for plant reproductive development,and inhibits their transcription.Overall,the study revealed a dual role of CsWRKY57L in promoting freezing tolerance via flavonoid biosynthesis and inhibiting reproductive development by regulating SWEETs expression.This study uncovers a novel mechanism whereby CsWRKY57L coordinately regulates both stress responses and growth in tea plants,providing a molecular basis for breeding low-temperature-tolerant varieties with restricted reproductive development.展开更多
Body size control is fundamental to development and requires proper energy engagement.One of the key energy sensing factors is AMP-activated protein kinase(AMPK),which regulates glucose uptake to ensure ATP production...Body size control is fundamental to development and requires proper energy engagement.One of the key energy sensing factors is AMP-activated protein kinase(AMPK),which regulates glucose uptake to ensure ATP production and nutrition supply during development.Here,we identify that the mutation of xgr,a gene encoding an ATPase,results in a reduced body size in Drosophila.Xgr is primarily expressed in the epithelial cells of the Malpighian tubules and the midguts.Loss of xgr leads to the inactivation of the AMPK signaling due to an increased ATP level.Glucose reabsorption in the Malpighian tubules is significantly reduced,as the Glut1 translocation to the plasma membrane is significantly disrupted in the absence of Xgr function.Our results suggest that Xgr function in the Malpighian tubules is essential to systemic glucose supply and energy homeostasis at the organismal level,thereby impacting body size.Our findings provide a mechanistic connection between energy homeostasis and animal size control during development.展开更多
The mechanistic target of rapamycin(m TOR) is a serinehreonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regulat...The mechanistic target of rapamycin(m TOR) is a serinehreonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regulates diverse aspects of neural development and function. Genetic mutations within the m TOR pathway lead to severe neurodevelopmental disorders, collectively known as “mTORopathies”(Crino, 2020). Dysfunctions of m TOR, including both its hyperactivation and hypoactivation, have also been implicated in a wide spectrum of other neurodevelopmental and neurodegenerative conditions, highlighting its importance in CNS health.展开更多
Phytochrome-interacting factors(PIFs)have been established as negative regulators of vascular patterning and xylem differentiation in the herbaceous plant Arabidopsis thaliana,however,the regulatory role of PIFs in se...Phytochrome-interacting factors(PIFs)have been established as negative regulators of vascular patterning and xylem differentiation in the herbaceous plant Arabidopsis thaliana,however,the regulatory role of PIFs in secondary growth in woody species remains unclear.Here,we examines the expression patterns and involvement of PtoPIF3.1 and PtoPIF3.2 during stem growth and secondary xylem development in Populus tomentosa.Overexpression of either PtoPIF3.1 or PtoPIF3.2 significantly enhances both longitudinal stem growth and radial wood development.Conversely,Ptopif3.1 and Ptopif3.2 mutants generated by CRISPR-mediated genome editing exhibit reciprocal phenotypic defects.Exogenous auxin application partially restores the phenotypes of Ptopif3.1 and Ptopif3.2 mutants,and the auxin biosynthesis-deficient mutant Ptoyuc8 exhibits developmental abnormalities similar to those observed in Ptopif3 mutants.Further analysis reveal that PtoPIF3s directly bind to and activate expression of PtoYUC8 and cell expansion-related genes PtoEXPA1.1/1.2,while modulating cambial division and expression of secondary xylem development marker genes(PtoWOX4,PtoANT,PtoCYCD3s,and PtoHB7/8)through auxin-mediated signaling.Together,our findings establish PtoPIF3.1/3.2 as key regulators that coordinate stem elongation and secondary growth in Populus,highlighting the functional divergence of PIF homologs between herbaceous and woody species.展开更多
The fruit of Amomum villosum is highly valued for its medicinal and edible properties.However,the fruit abscission rate is exceptionally high,resulting in low unit yield.To better understand the fruit growth and devel...The fruit of Amomum villosum is highly valued for its medicinal and edible properties.However,the fruit abscission rate is exceptionally high,resulting in low unit yield.To better understand the fruit growth and development,this study investigated the characteristic changes of fruits and the expression patterns of GA-related genes in both fruits and fruit stalks.Results revealed that it takes approximately 90 days for the ovary of A.villosum to reach maturity.Fruit growth pattern exhibited a slow-fast-slow trend,with the peak of fruit weight accumulation occurring between the 14 and 25 days after artificial pollination(DAP).Before the 27 DAP,significant changes were observed in the ovary,fruit color,pericarp thickness,and fruit thorn length.Additionally,ten candidate GA-related genes,including 1 GA13ox,1 GA20ox,1 GA3ox,2 GA2oxs,4 GID1cs,and 1 DELLA,were analyzed using bioinformatics tools.The GA-related genes in fruit and fruit stalk exhibited significant correlations with fruit growth/development and fruit dropping.Overall,the fruit growth and development law,and the expression patterns of GA-related genes provided a theoretical foundation for further functional study and the screening of candidate genes for potential applications in A.villosum.展开更多
The dental papilla(DP)is essential for the development of dentin and pulp.The extensive cellular heterogeneity within the DP is a critical factor underlying the complex and precise formation of dental structures durin...The dental papilla(DP)is essential for the development of dentin and pulp.The extensive cellular heterogeneity within the DP is a critical factor underlying the complex and precise formation of dental structures during odontogenesis.However,the critical cell types within human DP that play essential role in tooth development and regeneration remain largely uncharacterized.In this study,we analyzed the heterogeneity of human DP cells using single-cell sequencing and identified Gliomedin(GLDN)+DP stem cells(DPSCs)were a group of progenitors at an early stage of tooth development and play a key role in the development of pulp and dentin.GLDN+DPSCs strategically accumulate in human DP tissue near the interface of the newly formed dentin or pulp.Functional assays demonstrated that GLDN+DPSCs exhibited enhanced self-renewal,migratory capacity,and odontogenic differentiation potential in vitro compared to GLDN-DPSCs.Moreover,GLDN+DPSCs effectively induce the migration and tube formation of endothelial cells,which are essential for tooth development.The ectopic dental pulp regeneration model confirmed that GLDN+DPSCs can regenerate a vascularized dental pulp structure with an odontoblast layer in vivo.Given their functional capabilities,this population of cells has been designated as GLDN+odontogenic stem cells(OSCs).Mechanistically,GLDN is essential for maintaining the phenotype and function of GLDN+OSCs through BMP5 signaling via autocrine and paracrine mechanisms.In conclusion,this study identifies a previously uncharacterized essential subpopulation of OSCs essential for dental pulp development and regeneration.展开更多
Microfluidic technology,as an advanced experimental technique at the microscale,demonstrates significant potential for application in oil and gas reservoir development.By constructing microscopic models with varying p...Microfluidic technology,as an advanced experimental technique at the microscale,demonstrates significant potential for application in oil and gas reservoir development.By constructing microscopic models with varying pore structures and surface chemical properties,this technology can simulate fluid displacement behaviors in different types of reservoirs.Through the modification of fluid properties and displacement conditions in experiments,it allows for the quantitative analysis of fluid distribution characteristics during displacement processes.This provides valuable technical tools for studying the microscopic mechanisms of CO2 flooding,chemical flooding,and other enhanced oil/gas recovery techniques.This paper reviews the unique advantages of microfluidic technology in revealing pore-scale transport behaviors and optimizing development strategies,while also analyzing the current challenges associated with its application.With advancements in materials science and manufacturing technologies,microfluidic technology is expected to play an increasingly prominent role in reservoir development,offering new technical support for the efficient development of oil and gas reservoirs.展开更多
Aptamer therapeutics represent a class of target-based therapies that leverage their high specificity and affinity for diverse molecular targets.As single-stranded DNA or RNA oligonucleotides,aptamers offer advantages...Aptamer therapeutics represent a class of target-based therapies that leverage their high specificity and affinity for diverse molecular targets.As single-stranded DNA or RNA oligonucleotides,aptamers offer advantages in therapeutic applications.A critical aspect of aptamer drug development is the selection process,which has seen significant advancements through various in vitro selection methods,including Systematic Evolution of Ligands by Exponential Enrichment and its emerging variations.Recent progress has also introduced functional screening strategies that directly identify pharmacologically active aptamers,accelerating drug discovery.The applications of aptamers in disease treatment are expanding across oncology,neurodegenerative disorders,infectious diseases and other diseases.Aptamers exhibit versatile mechanisms of action,including blocking interactions,recruiting protein machinery,and inhibiting target functions.By addressing key limitations and presenting future directions,this review provides a comprehensive perspective on the recent evolving landscape of aptamer technology and its transformative potential in modern medicine.展开更多
Stem cell therapy shows promise for treating brain injuries;neural stem cells in particular are capable of repairing damage by forming new nerve cells and supporting recovery.However,optimizing the implantation and fu...Stem cell therapy shows promise for treating brain injuries;neural stem cells in particular are capable of repairing damage by forming new nerve cells and supporting recovery.However,optimizing the implantation and functionality of these cells in damaged brain regions remains challenging.Silk fibroin,a natural protein derived from silkworm silk,is a biocompatible material with exceptional properties that are useful for tissue engineering.Its biodegradability,mechanical robustness,and ability to promote cell growth make it particularly valuable for biomedical applications.Silk fibroin nanomaterials,which comprise silk fibroin processed into nanostructures,offer enhanced surface area,improved loading capacity for bioactive molecules,and superior nanoscale interactions with cells compared with bulk silk fibroin materials.In this study,we first extracted human-derived neural stem cells from a 14-week-old human fetus.Then,neural stem cells were loaded with 1%silk fibroin nanomaterials,which was identified as the optimal concentration to support human-derived neural stem cell growth and release of neurotrophic factors.Finally,1%silk fibroin nanomaterials were implanted into a rat model of hypoxic-ischemic brain injury.The results showed that,compared with the treatment with human-derived neural stem cells alone,silk fibroin hydrogel carrying human-derived neural stem cells was significantly more effective at alleviating brain tissue damage,increasing neurotrophic factor secretion in the brain microenvironment,and promoting motor and cognitive function recovery.These findings suggest that silk fibroin nanomaterials loaded with human-derived neural stem cells could be used to treat hypoxic-ischemic encephalopathy.However,the mechanisms and related signaling pathways by which hydrogels combined with cells exert their reparative effects still require further in-depth investigation.展开更多
The shift toward specialized and large-scale agricultural production has spurred the emergence of agricultural clusters as key forces of rural vitalization and sustainable development.This paper explored the formation...The shift toward specialized and large-scale agricultural production has spurred the emergence of agricultural clusters as key forces of rural vitalization and sustainable development.This paper explored the formation and evolution of Meizhou pomelo industry cluster in China,focusing on its role in restructuring rural socio-economic systems and integrating the whole value chains.Based on a case study employing qualitative methods such as in-depth interviews and participatory observation,the agricultural cluster evolution of Meizhou pomelo was categorized into three key phases of initial decentralization,self-organized scaling,and reorganized clustering.Geographical proximity and industrial agglomeration constitute the physical foundation,while vertical/horizontal linkages,technologic-al innovation,and policy support enhance competitiveness.Special mechanisms emerge through localized social networks,farmer co-operatives’activation,and cross-regional market expansion.The cluster’s impact is manifested in the shift from extensive to standard-ized and modernized production,diversified and flexible livelihood of farmers,and the integration of agriculture with industry and ser-vices.The development of the whole value chain based on agricultural cluster represents a critical pathway for achieving agricultural modernization,encompassing both internal and external value chain optimization.Through quality assurance systems,product diversi-fication strategies,operational efficiency improvements,and brand enhancement,these clusters amplify product value propositions and market competitiveness.This systemic approach facilitates supply-demand coordination,enables resource synergies,and optimizes eco-nomic returns across the horizontal and vertical value chain.This paper argues that agricultural clusters serve as strategic catalysts for sustainable rural development by reconstructing local production systems,fostering innovation ecosystems,and aligning agricultural modernization.It contributes to debates on rural vitalization by demonstrating how agricultural clustering can reconfigure rural areas as hubs of ecological modernization,rather than mere urban peripheries.展开更多
Cases of widespread bone hydatid infection are relatively rare in clinical practice.In this study,we reported for the first time a validated integrated repair therapy for multiple bone tissues,including the hip,femur,...Cases of widespread bone hydatid infection are relatively rare in clinical practice.In this study,we reported for the first time a validated integrated repair therapy for multiple bone tissues,including the hip,femur,and knee,caused by echinococ cosis.Artificial intelligence(AI)was used to develop a targeted surgical plan and to design a personalized prosthesis.Finite element analysis(FEA)was used to optimize the mechanical effectiveness of a customized integrated replacement prosthesis and to model stress distribution in the surrounding bone.Three-dimensional(3 D)printing was used to fabricate a customized prosthesis.With the assistance of AI,FEA,and 3 D printing technology,a personalized surgical plan and customized prosthesis were successfully constructed based on the patient’s disease.This approach achieved a successful therapeutic effect,demonstrating that AI-assisted personalized medicine holds great promise for the future.展开更多
Coastal groundwater(CGW)systems in rapidly urbanizing regions face critical challenges in achieving Sustainable Development Goal(SDG),where anthropogenic pressures intersect with hydrogeological vulnerability.This stu...Coastal groundwater(CGW)systems in rapidly urbanizing regions face critical challenges in achieving Sustainable Development Goal(SDG),where anthropogenic pressures intersect with hydrogeological vulnerability.This study employs coupled isotopic-hydrogeochemical analysis and geostatistics to unravel hydrochemical driving forces compromising groundwater quality in the Jinjiang Downstream Watershed(DJW),Southeast China.The results indicated that groundwater was predominantly recharged from local atmospheric precipitation and lateral recharge from the adjacent boundaries.Hydrochemical distributions exhibited a distinct pattern,transitioning from HCO3-Ca to HCO3·Cl-Ca,and then to Cl-Mg·Ca/Na·Ca,reflecting processes ranging from freshwater recharge to seawater intrusion(SWI).Elevated nitrates were primarily attributed to domestic sewage leakage and septic tank leaching.Additionally,preferential flow posed a risk to deep groundwater quality,by facilitating the rapid transport of contaminants through rock fractures.Key driving forces of hydrochemistry included silicate dissolution with local runoff paths,SWI,and human activities.The study advocates for a governance paradigm integrating electrochemical sensor networks with machine learning-driven contaminant prediction and phased membrane bioreactor deployment,which synergistically reduce nitrate fluxes while maintaining aquifer freshening processes.This integrated approach establishes a scalable model for SDG-aligned groundwater management in vulnerable coastal zones,demonstrating how process-based insights can bridge scientific discovery and water security implementation.展开更多
In the knowledge economy era,the rapid flow channels represented by high-speed rail(HSR)and online information flow promote cross-border development between cities.This study constructed a conceptual model of cross-bo...In the knowledge economy era,the rapid flow channels represented by high-speed rail(HSR)and online information flow promote cross-border development between cities.This study constructed a conceptual model of cross-border development from the perspective of flow space.Taking the Yangtze River Delta Region(YRDR),China,as a case study,we apply the Speaker-listener Label Propagation Algorithm(SLPA)to detect the heterogeneity patterns of cross-border development shaped by HSR flow and information flow in 2021.Results show that cross-border development among cities is more evident under information flows compared to HSR flow.Furthermore,intra-provincial cross-border development predominates under HSR flow,whereas inter-provincial cross-border development is more frequent under in-formation flow.Additionally,information flow leads to more shared or competitive nodes in cross-border development across different communities.In the future,leveraging these nodes'intermediary role will be the key to driving the next phase of regional integration.This research will enhance and broaden the theoretical frameworks for cross-border integrated development,flow space,and regional coordinated development.展开更多
Systematically analyzing the impact mechanisms of policy on Land Use Conflict(LUC)is crucial for constructing effective conflict mitigation strategies.However,previous research on how policy influences LUC remains rel...Systematically analyzing the impact mechanisms of policy on Land Use Conflict(LUC)is crucial for constructing effective conflict mitigation strategies.However,previous research on how policy influences LUC remains relatively limited.Focusing on the indirect driving role of policy on LUC,this study proposed County Development Level(CDL)under Major Function Oriented Zone Planning(MFOZP)guidance as an intermediary variable,bridging the implicit influence of MFOZP and the explicit changes in LUC.Using the Beijing-Tianjin-Hebei(BTH)region in China as a case study,we analyzed the spatio-temporal evolution characteristics of LUC and CDL for the periods 2000-2010 and 2010-2020,before and after MFOZP implementation.Panel models and Geographically Weighted Regression(GWR)were employed to explore the mechanism by which CDL influences LUC under MFOZP guidance.The results show that:1)MFOZP implementation effectively alleviates land use pressure from regional development,with LUC continuously declining at a rate of 2.41%,while CDL exhibits slight growth(3.84%),during 2010-2020.2)Under MFOZP guidance,CDL reduces pressure on Land Use Structure Conflict(LUSC)and Land Use Process Conflict(LUPC),enhances its inhibitory effect on Land Use Function Conflict(LUFC),and significantly contributes to LUC coordination,with notable spatial heterogeneity.3)The coupling relationship between CDL and LUC has improved post-implementation.Based on this,tailored LUC coordination strategies are proposed for different functional zones.This study confirms the effectiveness of MFOZP in coordinating LUC and provides a scientific reference for LUC research under policy frameworks and the governance of LUC in the BTH region.展开更多
Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of mineral...Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of minerals,with reserves of at least 38 of over 80 widely used minerals worldwide accounting for more than30%of the global total reserves.Asia continent experienced three main tectonic evolution and mineralization stages:The Precambrian,the Paleozoic,and the Mesozoic to Cenozoic.The abundant mineral resources in this continent can be divided into seven first-order metallogenic belts(metallogenic domains),18 second-order metallogenic belts(metallogenic provinces),61 third-order metallogenic belts(metallogenic zones),and nine main minerogenetic series.Asia continent exhibits the most significant metallogenic specialization among all continents.Specifically,granite belts of Asia continent manifest pronounced metallogenic specialization of tin,rare metals,and porphyry Cu-Au-Mo deposits.Its maficultramafic rock belts and ophiolite belts display notable metallogenic specialization of lateritic nickel deposits and magmatic type chromite deposits,while its Mesozoic to Cenozoic basalt belts show remarkable metallogenic specialization of lateritic bauxite deposits.Consequently,many giant metallogenic belts were formed,including the Southeast Asian tin belt,the Qinghai-Xizang Plateau rare metal metallogenic belt,the Tethyan porphyry Cu-Au-Mo metallogenic belt,the circum-Pacific porphyry Cu-Au-Mo metallogenic belt,the Southeast Asian lateritic bauxite metallogenic belt,the Deccan Plateau lateritic bauxite metallogenic belt in India,the Southeast Asian lateritic nickel metallogenic belt,and the Tethyan magmatic type chromite metallogenic belt—all of which are significant metallogenic belts in Asia continent.Future mineral exploration in Asia should focus primarily on the Precambrian mineralization of ancient cratons,the Paleozoic mineralization of the Central Asian-Mongolian orogenic belt,and the Mesozoic to Cenozoic mineralization of the Tethyan and circum-Pacific mobile belts.Asia's mining industry not only underpins its own economic growth but also propels global economic development and industrialization,contributing significantly to the world economy.Asia boasts the highest production value of minerals,the largest annual production of minerals,and the greatest trade value of mineral products among all the continents,having emerged as the trade center of global mineral products and the center of the mining industry economy.China is identified as one of the few countries that possess the most comprehensive kinds of minerals,and its mining industry has supported and driven the economic development and industrialization of Asia and even the world.Standing as the largest mineral producer worldwide,China ranked first in the production of 28 mineral commodities in the world in 2022.Besides,China exhibits the highest annual production value of minerals and the largest trade value of mineral products among all countries.Therefore,China's demand for global mineral products influences the global supply and demand patterns of minerals and the world economic situation.展开更多
The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to ...The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to more than 30% of the world's population,predominantly in developing countries where per capita farmland and food supply are only 40% of those in developed nations(FAO 2018).Meeting the Zero Hunger target amid ongoing population growth in these regions requires a substantial increase in agricultural production while minimizing soil degradation and adverse ecological impacts.This challenge is shared by many countries across South Asia,Africa,and Central and South America.展开更多
1.Introduction Sustainable development is widely regarded as a crucial way for human civilization to survive.To operationalize sustainability across social,economic,and environmental dimensions,the United Nations adop...1.Introduction Sustainable development is widely regarded as a crucial way for human civilization to survive.To operationalize sustainability across social,economic,and environmental dimensions,the United Nations adopted the 17 Sustainable Development Goals(SDGs)and 169 targets as part of the 2030 Agenda for Sustainable Development in 2015(United Nations,2015).Until 2025,with the joint efforts of the world,SDGs have made significant progress in social resource allocation,disease prevention and control,and energy transformation,but the current rate of change remains insufficient to achieve all SDGs in 2030(United Nations Department of Economic and Social Affairs,2025).How to accelerate the high-quality implementation of SDGs,with only four years left until 2030,is one of the core issues in current sustainable development research.展开更多
摘要As the core driving force leading the new round of technological revolution and industrial transformation,artificial intelligence is profoundly reshaping the higher education ecosystem.Based on the background of artificial intelligence development,this paper expounds the value of AI technology in promoting the innovative development of higher education,explores the specific paths of AI technology empowering the innovative development of higher education from three dimensions of talent training,scientific research,and governance,and puts forward the required guarantee conditions.It aims to promote the in-depth integration of artificial intelligence and higher education,profoundly change the form of higher education,lead higher education towards a more personalized,precise,and intelligent development path,and provide reference for solving a series of problems encountered in the current development of higher education.
基金supported by the Portuguese Foundation for Science and Technology(Fundação para a Ciência e Tecnologia-FCT)it contributes to the Strategic Research Plan of the Centre for Marine Technology and Ocean Engineering(Grant No.UIDB/UIDP/00134/2020)funded the first author for his PhD Scholarship(Grant No.SFRH/BD/145602/2019).
摘要This paper presents an overview of the recent developments in hybrid wind-wave energy.With the focus on floating concepts,the possible configurations introduced in the literature are categorized and depicted,and the main conclusions obtained from the references are summarized.Moreover,offshore wind and wave resources are discussed in terms of complementarity and supplementarity,offering a new perspective to developing hybrid wind-wave energy systems that look for synergies not limited to maximizing power output.Then,the feasibility of the concepts under development is discussed in detail,with focus on technical feasibility,dynamic feasibility and limitations of the methods employed.The hybrid configurations that surpassed the experimental validation phase are highlighted,and the experimental results are summarized.By compiling more than 40 floating wind turbine concepts,new relations are drawn between power,wind turbine dimensions,platforms’draft and displacement,which are further related to the payload allowance of the units to accommodate wave devices and onboard power take-off systems.Bearing in mind that it is a challenge to model the exact dynamics of hybrid floating wind-wave platforms,this paper elucidates the current research gaps,limitations and future trends in the field.Lastly,based on the overview and topics discussed,several major conclusions are drawn concerning hybrid synergies,dynamics and hydrodynamics of hybrid platforms,feasibility of concepts,among other regards.
基金We would like to show gratitude to the Yunnan Province Basic Research Major Project(202501BC070006(Y.Wang))Key Industry Science and Technology Projects for University Services in Yunnan Province(FWCY ZNT2024002(Y.Wang))+3 种基金National Natural Science Foundation of China(22279070(L.Wang))and(U21A20170(X.He))the Ministry of Science and Technology of China(2019YFA0705703(L.Wang))Beijing Natural Science Foundation(L242005(X.He))Key Industry Science and Technology Projects for University Services in Yunnan Province(FWCY BSPY2024011(T.Lai)).
摘要Long-life energy storage batteries are integral to energy storage systems and electric vehicles,with lithium-ion batteries(LIBs)currently being the preferred option for extended usage-life energy storage.To further extend the life span of LIBs,it is essential to intensify investments in battery design,manufacturing processes,and the advancement of ancillary materials.The pursuit of long durability introduces new challenges for battery energy density.The advent of electrode material offers effective support in enhancing the battery’s long-duration performance.Often underestimated as part of the cathode composition,the binder plays a pivotal role in the longevity and electrochemical performance of the electrode.Maintaining the mechanical integrity of the electrode through judicious binder design is a fundamental requirement for achieving consistent long-life cycles and high energy density.This paper primarily concentrates on the commonly employed cathode systems in lithium-ion batteries,elucidates the significance of binders for both,discusses the application status,strengths,and weaknesses of novel binders,and ultimately puts forth corresponding optimization strategies.It underscores the critical function of binders in enhancing battery performance and advancing the sustainable development of lithium-ion batteries,aiming to offer fresh insights and perspectives for the design of high-performance LIBs.
基金supported by the National Natural Science Foundation of China(Grant Nos.32072630,32372774,and U22A20499)the earmarked fund for CARS(Grant No.CARS-19-01A).
摘要Tea plant(Camellia sinensis(L.)O.Kuntze)is a cold-sensitive leaf-harvesting crop whose growth,yield,and processed tea quality are all inhibited by low temperatures.Therefore,identifying the regulatory genes involved in tea plant growth and freezing tolerance is crucial for genetic improvement.WRKY transcription factors regulate various plant processes,including growth and development,stress responses,and metabolite biosynthesis.However,the molecular network through which WRKY coordinates these pathways in tea plants remains unclear.In this study,we revealed that CsWRKY57L,a cold-inducible WRKY IIc subfamily member,positively regulated freezing tolerance by directly promoting flavonoid accumulation in tea plants.Transient suppression of CsWRKY57L weakened the freezing tolerance of tea plants by reducing flavonoid content and suppressing the C-repeat-binding factor(CBF)-cold-responsive(COR)gene pathway.In contrast,heterologous overexpression of CsWRKY57L in Arabidopsis had the opposite effect.Additionally,overexpression of CsWRKY57L inhibited reproductive development and accelerated senescence in Arabidopsis.Interaction analysis revealed that CsWRKY57L directly binds to the promoters of CsSWEET1a,CsSWEET15,and AtSWEET15,which encode sugar transporters essential for plant reproductive development,and inhibits their transcription.Overall,the study revealed a dual role of CsWRKY57L in promoting freezing tolerance via flavonoid biosynthesis and inhibiting reproductive development by regulating SWEETs expression.This study uncovers a novel mechanism whereby CsWRKY57L coordinately regulates both stress responses and growth in tea plants,providing a molecular basis for breeding low-temperature-tolerant varieties with restricted reproductive development.
基金funded by the National Key R&D Program of China(2021YFA0805800,2023YFE0107700,and 2020YFA0803202 to R.J.),the 111 Project(D18010 to R.J.)the Guangzhou Medical University Discipline Construction Funds(Basic Medicine)(JCXKJS2022A02 to R.J.)+1 种基金Guangdong Basic and Applied Basic Research Foundation(2024A1515010752 to C.W.)the Special Innovation Projects of Universities in Guangdong Province(2022KTSCx096 to C.W.).
摘要Body size control is fundamental to development and requires proper energy engagement.One of the key energy sensing factors is AMP-activated protein kinase(AMPK),which regulates glucose uptake to ensure ATP production and nutrition supply during development.Here,we identify that the mutation of xgr,a gene encoding an ATPase,results in a reduced body size in Drosophila.Xgr is primarily expressed in the epithelial cells of the Malpighian tubules and the midguts.Loss of xgr leads to the inactivation of the AMPK signaling due to an increased ATP level.Glucose reabsorption in the Malpighian tubules is significantly reduced,as the Glut1 translocation to the plasma membrane is significantly disrupted in the absence of Xgr function.Our results suggest that Xgr function in the Malpighian tubules is essential to systemic glucose supply and energy homeostasis at the organismal level,thereby impacting body size.Our findings provide a mechanistic connection between energy homeostasis and animal size control during development.
基金supported by grants from Simons Foundation (SFARI 479754),CIHR (PJT-180565)the Scottish Rite Charitable Foundation of Canada (to YL)funding from the Canada Research Chairs program。
摘要The mechanistic target of rapamycin(m TOR) is a serinehreonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regulates diverse aspects of neural development and function. Genetic mutations within the m TOR pathway lead to severe neurodevelopmental disorders, collectively known as “mTORopathies”(Crino, 2020). Dysfunctions of m TOR, including both its hyperactivation and hypoactivation, have also been implicated in a wide spectrum of other neurodevelopmental and neurodegenerative conditions, highlighting its importance in CNS health.
基金upported by grants from the National Key Research and Development Program of China(2022YFD1201600)the National Natural Science Foundation of China(32371903).
摘要Phytochrome-interacting factors(PIFs)have been established as negative regulators of vascular patterning and xylem differentiation in the herbaceous plant Arabidopsis thaliana,however,the regulatory role of PIFs in secondary growth in woody species remains unclear.Here,we examines the expression patterns and involvement of PtoPIF3.1 and PtoPIF3.2 during stem growth and secondary xylem development in Populus tomentosa.Overexpression of either PtoPIF3.1 or PtoPIF3.2 significantly enhances both longitudinal stem growth and radial wood development.Conversely,Ptopif3.1 and Ptopif3.2 mutants generated by CRISPR-mediated genome editing exhibit reciprocal phenotypic defects.Exogenous auxin application partially restores the phenotypes of Ptopif3.1 and Ptopif3.2 mutants,and the auxin biosynthesis-deficient mutant Ptoyuc8 exhibits developmental abnormalities similar to those observed in Ptopif3 mutants.Further analysis reveal that PtoPIF3s directly bind to and activate expression of PtoYUC8 and cell expansion-related genes PtoEXPA1.1/1.2,while modulating cambial division and expression of secondary xylem development marker genes(PtoWOX4,PtoANT,PtoCYCD3s,and PtoHB7/8)through auxin-mediated signaling.Together,our findings establish PtoPIF3.1/3.2 as key regulators that coordinate stem elongation and secondary growth in Populus,highlighting the functional divergence of PIF homologs between herbaceous and woody species.
基金Supported by Seed Industry Vitalization Project of Rural Revitalization Strategy of Guangdong Province of China(2024-440000-90060000-8796)。
摘要The fruit of Amomum villosum is highly valued for its medicinal and edible properties.However,the fruit abscission rate is exceptionally high,resulting in low unit yield.To better understand the fruit growth and development,this study investigated the characteristic changes of fruits and the expression patterns of GA-related genes in both fruits and fruit stalks.Results revealed that it takes approximately 90 days for the ovary of A.villosum to reach maturity.Fruit growth pattern exhibited a slow-fast-slow trend,with the peak of fruit weight accumulation occurring between the 14 and 25 days after artificial pollination(DAP).Before the 27 DAP,significant changes were observed in the ovary,fruit color,pericarp thickness,and fruit thorn length.Additionally,ten candidate GA-related genes,including 1 GA13ox,1 GA20ox,1 GA3ox,2 GA2oxs,4 GID1cs,and 1 DELLA,were analyzed using bioinformatics tools.The GA-related genes in fruit and fruit stalk exhibited significant correlations with fruit growth/development and fruit dropping.Overall,the fruit growth and development law,and the expression patterns of GA-related genes provided a theoretical foundation for further functional study and the screening of candidate genes for potential applications in A.villosum.
基金supported by grants from the National Key Research and Development Program of China(2022YFA1104400)the National Natural Science Foundation of China(32271365,32471183,U21A20369)+1 种基金Sichuan Science and Technology program(2023YFS0151,2023YFS0056)the Fundamental Research Funds for the Central Universities(SCU2023D014)。
摘要The dental papilla(DP)is essential for the development of dentin and pulp.The extensive cellular heterogeneity within the DP is a critical factor underlying the complex and precise formation of dental structures during odontogenesis.However,the critical cell types within human DP that play essential role in tooth development and regeneration remain largely uncharacterized.In this study,we analyzed the heterogeneity of human DP cells using single-cell sequencing and identified Gliomedin(GLDN)+DP stem cells(DPSCs)were a group of progenitors at an early stage of tooth development and play a key role in the development of pulp and dentin.GLDN+DPSCs strategically accumulate in human DP tissue near the interface of the newly formed dentin or pulp.Functional assays demonstrated that GLDN+DPSCs exhibited enhanced self-renewal,migratory capacity,and odontogenic differentiation potential in vitro compared to GLDN-DPSCs.Moreover,GLDN+DPSCs effectively induce the migration and tube formation of endothelial cells,which are essential for tooth development.The ectopic dental pulp regeneration model confirmed that GLDN+DPSCs can regenerate a vascularized dental pulp structure with an odontoblast layer in vivo.Given their functional capabilities,this population of cells has been designated as GLDN+odontogenic stem cells(OSCs).Mechanistically,GLDN is essential for maintaining the phenotype and function of GLDN+OSCs through BMP5 signaling via autocrine and paracrine mechanisms.In conclusion,this study identifies a previously uncharacterized essential subpopulation of OSCs essential for dental pulp development and regeneration.
基金funded by the Key Science Foundation of Laboratory of Marine Oil&Gas Reservoirs Production,Sinopec(33550000-22-ZC0613-0332).
摘要Microfluidic technology,as an advanced experimental technique at the microscale,demonstrates significant potential for application in oil and gas reservoir development.By constructing microscopic models with varying pore structures and surface chemical properties,this technology can simulate fluid displacement behaviors in different types of reservoirs.Through the modification of fluid properties and displacement conditions in experiments,it allows for the quantitative analysis of fluid distribution characteristics during displacement processes.This provides valuable technical tools for studying the microscopic mechanisms of CO2 flooding,chemical flooding,and other enhanced oil/gas recovery techniques.This paper reviews the unique advantages of microfluidic technology in revealing pore-scale transport behaviors and optimizing development strategies,while also analyzing the current challenges associated with its application.With advancements in materials science and manufacturing technologies,microfluidic technology is expected to play an increasingly prominent role in reservoir development,offering new technical support for the efficient development of oil and gas reservoirs.
基金supported by the National Key Research&Development Program of China(Grant No.:2022YFA1304500)the National Natural Science Foundation of China(Grant Nos.:22227805,and 22374004)+1 种基金Excellent Young Scientists Fund Program(Overseas)Clinical Medicine Plus X-Young Scholars Project of Peking University,the Fundamental Research Funds for the Central Universities(Grant No.:PKU2024LCXQ026).
摘要Aptamer therapeutics represent a class of target-based therapies that leverage their high specificity and affinity for diverse molecular targets.As single-stranded DNA or RNA oligonucleotides,aptamers offer advantages in therapeutic applications.A critical aspect of aptamer drug development is the selection process,which has seen significant advancements through various in vitro selection methods,including Systematic Evolution of Ligands by Exponential Enrichment and its emerging variations.Recent progress has also introduced functional screening strategies that directly identify pharmacologically active aptamers,accelerating drug discovery.The applications of aptamers in disease treatment are expanding across oncology,neurodegenerative disorders,infectious diseases and other diseases.Aptamers exhibit versatile mechanisms of action,including blocking interactions,recruiting protein machinery,and inhibiting target functions.By addressing key limitations and presenting future directions,this review provides a comprehensive perspective on the recent evolving landscape of aptamer technology and its transformative potential in modern medicine.
基金Dalian Science and Technology Talent Innovation Support Policy Implementation Plan High-Level Talent Team,No.2022RG18(to JL)the Science and Technology Plan Orientation of Liaoning Province,No.[2021]49(to JL)+1 种基金Dalian High-Level Talent Innovation Support Plan,No.2021RQ028(to CH)Natural Science Foundation of Liaoning Province,No.2022-BS-238(to CH).
摘要Stem cell therapy shows promise for treating brain injuries;neural stem cells in particular are capable of repairing damage by forming new nerve cells and supporting recovery.However,optimizing the implantation and functionality of these cells in damaged brain regions remains challenging.Silk fibroin,a natural protein derived from silkworm silk,is a biocompatible material with exceptional properties that are useful for tissue engineering.Its biodegradability,mechanical robustness,and ability to promote cell growth make it particularly valuable for biomedical applications.Silk fibroin nanomaterials,which comprise silk fibroin processed into nanostructures,offer enhanced surface area,improved loading capacity for bioactive molecules,and superior nanoscale interactions with cells compared with bulk silk fibroin materials.In this study,we first extracted human-derived neural stem cells from a 14-week-old human fetus.Then,neural stem cells were loaded with 1%silk fibroin nanomaterials,which was identified as the optimal concentration to support human-derived neural stem cell growth and release of neurotrophic factors.Finally,1%silk fibroin nanomaterials were implanted into a rat model of hypoxic-ischemic brain injury.The results showed that,compared with the treatment with human-derived neural stem cells alone,silk fibroin hydrogel carrying human-derived neural stem cells was significantly more effective at alleviating brain tissue damage,increasing neurotrophic factor secretion in the brain microenvironment,and promoting motor and cognitive function recovery.These findings suggest that silk fibroin nanomaterials loaded with human-derived neural stem cells could be used to treat hypoxic-ischemic encephalopathy.However,the mechanisms and related signaling pathways by which hydrogels combined with cells exert their reparative effects still require further in-depth investigation.
基金Under the auspices of the Key Projects of Philosophy and Social Sciences Research,Ministry of Education of China(No.23JZD008)National Natural Science Foundation of China(No.42171193)+2 种基金Key Project of Guangdong Provincial Philosophy and Social Sciences Planning(No.GD24ES013,GD25ZX04)2025 Guangzhou Basic and Applied Basic Research Special Project(No.2025A04J7127)Fundamental Research Funds for the Central Universities,Sun Yat-sen University(No.24wkjc11)。
摘要The shift toward specialized and large-scale agricultural production has spurred the emergence of agricultural clusters as key forces of rural vitalization and sustainable development.This paper explored the formation and evolution of Meizhou pomelo industry cluster in China,focusing on its role in restructuring rural socio-economic systems and integrating the whole value chains.Based on a case study employing qualitative methods such as in-depth interviews and participatory observation,the agricultural cluster evolution of Meizhou pomelo was categorized into three key phases of initial decentralization,self-organized scaling,and reorganized clustering.Geographical proximity and industrial agglomeration constitute the physical foundation,while vertical/horizontal linkages,technologic-al innovation,and policy support enhance competitiveness.Special mechanisms emerge through localized social networks,farmer co-operatives’activation,and cross-regional market expansion.The cluster’s impact is manifested in the shift from extensive to standard-ized and modernized production,diversified and flexible livelihood of farmers,and the integration of agriculture with industry and ser-vices.The development of the whole value chain based on agricultural cluster represents a critical pathway for achieving agricultural modernization,encompassing both internal and external value chain optimization.Through quality assurance systems,product diversi-fication strategies,operational efficiency improvements,and brand enhancement,these clusters amplify product value propositions and market competitiveness.This systemic approach facilitates supply-demand coordination,enables resource synergies,and optimizes eco-nomic returns across the horizontal and vertical value chain.This paper argues that agricultural clusters serve as strategic catalysts for sustainable rural development by reconstructing local production systems,fostering innovation ecosystems,and aligning agricultural modernization.It contributes to debates on rural vitalization by demonstrating how agricultural clustering can reconfigure rural areas as hubs of ecological modernization,rather than mere urban peripheries.
基金partially supported by the National Natural Science Foundation of China(Nos.32471474 and 82102574)the Precision Medicine Project of People’s Hospital of Xinjiang Uygur Autonomous Region(No.20220305)+4 种基金Chengdu Advanced Metal Materials Industry Technology Research Institute Co.,Ltd.Support Project(No.24H0802)Sichuan Science and Technology Program(Nos.2025YFHZ0086,2023YFS0053,2024YFHZ0125,and 2025ZNSFSC0381)Project of Tianfu Jincheng Laboratory(No.2025ZH009)Guangdong Basic and Applied Basic Research Foundation(No.2023A1515220102)Xinjiang Autonomous Region Science and Technology Support Project Plan(Directive)Project(No.2024E02049)。
摘要Cases of widespread bone hydatid infection are relatively rare in clinical practice.In this study,we reported for the first time a validated integrated repair therapy for multiple bone tissues,including the hip,femur,and knee,caused by echinococ cosis.Artificial intelligence(AI)was used to develop a targeted surgical plan and to design a personalized prosthesis.Finite element analysis(FEA)was used to optimize the mechanical effectiveness of a customized integrated replacement prosthesis and to model stress distribution in the surrounding bone.Three-dimensional(3 D)printing was used to fabricate a customized prosthesis.With the assistance of AI,FEA,and 3 D printing technology,a personalized surgical plan and customized prosthesis were successfully constructed based on the patient’s disease.This approach achieved a successful therapeutic effect,demonstrating that AI-assisted personalized medicine holds great promise for the future.
基金supported by the project of the China Geological Survey(DD20230421)the Central Institutes Fundamental Research Project(SK202410)the National Natural Science Foundation of China(41702283).
摘要Coastal groundwater(CGW)systems in rapidly urbanizing regions face critical challenges in achieving Sustainable Development Goal(SDG),where anthropogenic pressures intersect with hydrogeological vulnerability.This study employs coupled isotopic-hydrogeochemical analysis and geostatistics to unravel hydrochemical driving forces compromising groundwater quality in the Jinjiang Downstream Watershed(DJW),Southeast China.The results indicated that groundwater was predominantly recharged from local atmospheric precipitation and lateral recharge from the adjacent boundaries.Hydrochemical distributions exhibited a distinct pattern,transitioning from HCO3-Ca to HCO3·Cl-Ca,and then to Cl-Mg·Ca/Na·Ca,reflecting processes ranging from freshwater recharge to seawater intrusion(SWI).Elevated nitrates were primarily attributed to domestic sewage leakage and septic tank leaching.Additionally,preferential flow posed a risk to deep groundwater quality,by facilitating the rapid transport of contaminants through rock fractures.Key driving forces of hydrochemistry included silicate dissolution with local runoff paths,SWI,and human activities.The study advocates for a governance paradigm integrating electrochemical sensor networks with machine learning-driven contaminant prediction and phased membrane bioreactor deployment,which synergistically reduce nitrate fluxes while maintaining aquifer freshening processes.This integrated approach establishes a scalable model for SDG-aligned groundwater management in vulnerable coastal zones,demonstrating how process-based insights can bridge scientific discovery and water security implementation.
基金Under the Key Laboratory of Natural Resources Monitoring in Tropical and Subtropical Area of South China,Ministry of Natural Resources(No.2024NRMK08)the National Natural Science Foundation of China(No.42101160)。
摘要In the knowledge economy era,the rapid flow channels represented by high-speed rail(HSR)and online information flow promote cross-border development between cities.This study constructed a conceptual model of cross-border development from the perspective of flow space.Taking the Yangtze River Delta Region(YRDR),China,as a case study,we apply the Speaker-listener Label Propagation Algorithm(SLPA)to detect the heterogeneity patterns of cross-border development shaped by HSR flow and information flow in 2021.Results show that cross-border development among cities is more evident under information flows compared to HSR flow.Furthermore,intra-provincial cross-border development predominates under HSR flow,whereas inter-provincial cross-border development is more frequent under in-formation flow.Additionally,information flow leads to more shared or competitive nodes in cross-border development across different communities.In the future,leveraging these nodes'intermediary role will be the key to driving the next phase of regional integration.This research will enhance and broaden the theoretical frameworks for cross-border integrated development,flow space,and regional coordinated development.
基金Under the auspices of the National Key Research and Development Program of China(No.2018YFD1100803)the Fundamental Research Fund for the Central Universities(Ph.D.Top Innovative Talents Fund of CUMTB)(No.BBJ2024029)。
摘要Systematically analyzing the impact mechanisms of policy on Land Use Conflict(LUC)is crucial for constructing effective conflict mitigation strategies.However,previous research on how policy influences LUC remains relatively limited.Focusing on the indirect driving role of policy on LUC,this study proposed County Development Level(CDL)under Major Function Oriented Zone Planning(MFOZP)guidance as an intermediary variable,bridging the implicit influence of MFOZP and the explicit changes in LUC.Using the Beijing-Tianjin-Hebei(BTH)region in China as a case study,we analyzed the spatio-temporal evolution characteristics of LUC and CDL for the periods 2000-2010 and 2010-2020,before and after MFOZP implementation.Panel models and Geographically Weighted Regression(GWR)were employed to explore the mechanism by which CDL influences LUC under MFOZP guidance.The results show that:1)MFOZP implementation effectively alleviates land use pressure from regional development,with LUC continuously declining at a rate of 2.41%,while CDL exhibits slight growth(3.84%),during 2010-2020.2)Under MFOZP guidance,CDL reduces pressure on Land Use Structure Conflict(LUSC)and Land Use Process Conflict(LUPC),enhances its inhibitory effect on Land Use Function Conflict(LUFC),and significantly contributes to LUC coordination,with notable spatial heterogeneity.3)The coupling relationship between CDL and LUC has improved post-implementation.Based on this,tailored LUC coordination strategies are proposed for different functional zones.This study confirms the effectiveness of MFOZP in coordinating LUC and provides a scientific reference for LUC research under policy frameworks and the governance of LUC in the BTH region.
基金funded by geological survey project of China Geological Survey(DD20211404)。
摘要Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of minerals,with reserves of at least 38 of over 80 widely used minerals worldwide accounting for more than30%of the global total reserves.Asia continent experienced three main tectonic evolution and mineralization stages:The Precambrian,the Paleozoic,and the Mesozoic to Cenozoic.The abundant mineral resources in this continent can be divided into seven first-order metallogenic belts(metallogenic domains),18 second-order metallogenic belts(metallogenic provinces),61 third-order metallogenic belts(metallogenic zones),and nine main minerogenetic series.Asia continent exhibits the most significant metallogenic specialization among all continents.Specifically,granite belts of Asia continent manifest pronounced metallogenic specialization of tin,rare metals,and porphyry Cu-Au-Mo deposits.Its maficultramafic rock belts and ophiolite belts display notable metallogenic specialization of lateritic nickel deposits and magmatic type chromite deposits,while its Mesozoic to Cenozoic basalt belts show remarkable metallogenic specialization of lateritic bauxite deposits.Consequently,many giant metallogenic belts were formed,including the Southeast Asian tin belt,the Qinghai-Xizang Plateau rare metal metallogenic belt,the Tethyan porphyry Cu-Au-Mo metallogenic belt,the circum-Pacific porphyry Cu-Au-Mo metallogenic belt,the Southeast Asian lateritic bauxite metallogenic belt,the Deccan Plateau lateritic bauxite metallogenic belt in India,the Southeast Asian lateritic nickel metallogenic belt,and the Tethyan magmatic type chromite metallogenic belt—all of which are significant metallogenic belts in Asia continent.Future mineral exploration in Asia should focus primarily on the Precambrian mineralization of ancient cratons,the Paleozoic mineralization of the Central Asian-Mongolian orogenic belt,and the Mesozoic to Cenozoic mineralization of the Tethyan and circum-Pacific mobile belts.Asia's mining industry not only underpins its own economic growth but also propels global economic development and industrialization,contributing significantly to the world economy.Asia boasts the highest production value of minerals,the largest annual production of minerals,and the greatest trade value of mineral products among all the continents,having emerged as the trade center of global mineral products and the center of the mining industry economy.China is identified as one of the few countries that possess the most comprehensive kinds of minerals,and its mining industry has supported and driven the economic development and industrialization of Asia and even the world.Standing as the largest mineral producer worldwide,China ranked first in the production of 28 mineral commodities in the world in 2022.Besides,China exhibits the highest annual production value of minerals and the largest trade value of mineral products among all countries.Therefore,China's demand for global mineral products influences the global supply and demand patterns of minerals and the world economic situation.
摘要The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to more than 30% of the world's population,predominantly in developing countries where per capita farmland and food supply are only 40% of those in developed nations(FAO 2018).Meeting the Zero Hunger target amid ongoing population growth in these regions requires a substantial increase in agricultural production while minimizing soil degradation and adverse ecological impacts.This challenge is shared by many countries across South Asia,Africa,and Central and South America.
基金supported by the Key Special Project of“Intergovernmental International Scientific and Technological Innovation Cooperation”in the National Key Research and Development Program(Grant No.2025YFE0111302)the Ningbo Natural Science Foundation(Grant No.2024J013)the Natural Science Foundation of Xiamen,China(Grants No.3502Z202573087 and 3502Z202572040)。
摘要1.Introduction Sustainable development is widely regarded as a crucial way for human civilization to survive.To operationalize sustainability across social,economic,and environmental dimensions,the United Nations adopted the 17 Sustainable Development Goals(SDGs)and 169 targets as part of the 2030 Agenda for Sustainable Development in 2015(United Nations,2015).Until 2025,with the joint efforts of the world,SDGs have made significant progress in social resource allocation,disease prevention and control,and energy transformation,but the current rate of change remains insufficient to achieve all SDGs in 2030(United Nations Department of Economic and Social Affairs,2025).How to accelerate the high-quality implementation of SDGs,with only four years left until 2030,is one of the core issues in current sustainable development research.