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CFD study on gas-solid hydrodynamics during the scale-up of high-density circulating fluidized bed 认领 引用
1
作者 Ming-Zhu Lv Yun-Peng Zhao +4 位作者 Min Wang Cheng-Xiu Wang Xing-Ying Lan Jin-Sen Gao Xiao-Gang Shi 《Petroleum Science》 SCIE EI CAS CSCD 2026年第1期464-474,共11页
High-density circulating fluidized bed(HDCFB)offers high gas-solid contact efficiency and shows great application prospects in the petrochemical industry.It is important to study the scale-up of HDCFB for its successf... High-density circulating fluidized bed(HDCFB)offers high gas-solid contact efficiency and shows great application prospects in the petrochemical industry.It is important to study the scale-up of HDCFB for its successful industrial application.Therefore,the gas-solid hydrodynamics of the full-loop HDCFB with different riser heights and riser diameters was systematically investigated by coupling a Euler-Euler model,an energy minimization multi-scale(EMMS)drag model,and a modified solid pressure model.Results demonstrated that the solids circulation rate of the HDCFB system decreases with increasing riser height.When the riser height is 10 m,it is difficult to achieve full development of gassolid flow.When the riser height increases to 18 m,full development is achieved at a normalized height(h/H)of 0.35.At high solids circulation rates,high riser heights are required to achieve sufficient gassolid flow development,and adequate storage height is needed to provide the driving force for highdensity operation of the circulating fluidized bed.As the riser diameter increases,the pressure drop in each unit of the HDCFB system changes linearly,with the pressure drop in the riser decreasing and the pressure drop in the cyclone separator increasing.In large-diameter risers,the radial distribution of particle concentration and particle velocity inside the riser becomes less uniform,and larger particle clusters can form near the wall with severe particle back-mixing.When the riser diameter increases from 80 to 150 mm,the normalized height of the fully developed gas-solid region increases from 0.15 to0.42(h/H),indicating that particles and clusters in large-diameter risers need a longer acceleration zone to develop a stable flow pattern.These findings can provide useful information for the design and scaleup of HDCFB systems. 展开更多
关键词 Scale-up HDCFB CFD Hydrodynamics Riser height Riser diameter
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Multi-Phase CFD Simulation of Lifeboat Free-Fall Launch Dynamics with Varying Pitch Angles 认领 引用 被引量：1
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作者 M.Silveira S.Wang C.Guedes Soares 《哈尔滨工程大学学报（英文版）》 CSCD 2026年第3期657-668,共12页
The objective of this study is to simulate the free-fall launch of a lifeboat and to analyse its trajectory,pitch angle,velocity,acceleration,and pressure dynamics using Open Field Operation and Manipulation(OpenFOAM)... The objective of this study is to simulate the free-fall launch of a lifeboat and to analyse its trajectory,pitch angle,velocity,acceleration,and pressure dynamics using Open Field Operation and Manipulation(OpenFOAM).Utilising the overset grid technique,which is well-suited for handling the expected large motions,the study employs multi-phase simulations based on the volume of fluid method.A series of 21 simulations is conducted,varying initial pitch angles and three different drop heights to thoroughly examine the lifeboat's behaviour under various conditions.The analysis of pressure across multiple points along the same transversal and longitudinal planes reveals two significant pressure peaks:one at the bow during water entry and another at the stern,occurring after a secondary water entry triggered by turn-back spins due to restoring moments.Pressure contours indicate that the keel experiences the highest loads,highlighting it as a critical area of concern.Additionally,the kinematics of each scenario is analysed to determine which initial pitch angle would allow the lifeboat to distance itself most effectively from potential hazards without additional impulse.This aspect of the study aims to identify optimal launch conditions that enhance safety and minimise risk during emergency deployments. 展开更多
关键词 CFD simulation Water entry Free-fall launch Lifeboat Overset mesh
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Melatonin and Mitochondrial Function:Insights into Bioenergetics,Dynamics,and Gene Regulation 认领 引用 被引量：2
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作者 Silvia Carloni Maria Gemma Nasoni +6 位作者 Serafina Perrone Erik Bargagni Carla Gentile Walter Manucha Russel JReiter Francesca Luchetti Walter Balduini 《BIOCELL》 SCIE 2026年第2期1-22,共22页
Mitochondria are central regulators of cellular energy metabolism,redox balance,and survival,and their dysfunction contributes to neurodegenerative,cardiovascular,and metabolic diseases,as well as aging.Beyond its rol... Mitochondria are central regulators of cellular energy metabolism,redox balance,and survival,and their dysfunction contributes to neurodegenerative,cardiovascular,and metabolic diseases,as well as aging.Beyond its role as a circadian hormone,melatonin is now recognized as a key modulator of mitochondrial physiology.This review provides an overview of the mechanisms by which melatonin can preserve mitochondrial function through multifaceted mechanisms.Experimental evidence shows that melatonin enhances the activity of electron transport chain(ETC)complexes,stabilizes the mitochondrial membrane potential(Δψ),and prevents cardiolipin(CL)peroxidation,thereby limiting permeability transition pore(mPTP)opening and cytochrome c release.Through its direct radical scavenging capacity and the upregulation of mitochondrial antioxidant defenses,melatonin protects against oxidative stress(OS)and preserves mitochondrial DNA integrity.Melatonin also regulates mitochondrial dynamics by promoting fusion,restraining excessive fission,and supporting quality control mechanisms such as mitophagy,unfolded protein response(UPR),and proteostasis.Moreover,melatonin influences mitochondrial biogenesis and intercellular communication through tunneling nanotubes(TNTs)and mitokine signaling.Thus,melatonin may represent a promising multifaceted therapeutic strategy for preserving mitochondrial homeostasis in a range of pathological conditions,including neurodegeneration and cardiovascular and metabolic diseases.However,a significant translational gap still remains between the promising preclinical data and the established clinical practice.Therefore,the aim of this review is to provide a comprehensive synthesis of current knowledge on the mechanisms through which melatonin modulates mitochondrial function and to discuss its potential therapeutic implications in neurodegenerative,cardiovascular,and metabolic diseases. 展开更多
关键词 Melatonin mitochondrial bioenergetics mitochondrial dynamics oxidative stress tunneling nanotubes mitokines
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Numerical simulation and analysis of risk factors leading to pancreaticobiliary reflux:Insights from a computational fluid dynamics study to idealized models 认领 引用 被引量：1
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作者 Nian-Zong Hou Zhao-Guang Wang +5 位作者 Guan-Qing Xiong Ming-Zhe Li Yan Hou Hai Hu Kai Wang Yu-Long Yang 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2026年第2期198-211,共14页
Background:The analysis and prediction of pancreaticobiliary reflux(PBR)play a crucial role in planning surgical interventions for hepato-biliary-pancreatic diseases,considering the uncertain mechanism behind it.Howev... Background:The analysis and prediction of pancreaticobiliary reflux(PBR)play a crucial role in planning surgical interventions for hepato-biliary-pancreatic diseases,considering the uncertain mechanism behind it.However,current practices are limited by fragmented clinical observations,making it challenging to visualize the complex phenomenon in the pancreaticobiliary junction(PBJ)through imaging and radiography experiments.This study aimed to comprehensively describe the retrograde flow characteristics in various PBR scenarios and assess the factors leading to PBR using simulations based on idealized geometry and boundary conditions.Methods:By Cadence Pointwise,we developed a computational fluid dynamics(CFD)model using an idealized PBJ system.Standard parameters such as pressure and viscosity were applied,along with typical assumptions relevant to fluid dynamic modeling.Subsequently,based on the aforementioned basic idealized model,we analyzed 8 hypothetical PBR conditions,covering a range of high(shorter)and low(longer)values or different positions for each specific parameter,at a representative stage of a peristaltic propagation cycle of the Oddi's sphincter.Results:We modeled a two-dimensional PBJ with the propagation of a peristaltic wave.These findings demonstrated that the shortened septum,the extended ampulla,the increased wavelength and enhanced amplitude of the Oddi's sphincterial peristalsis,the widened diameter difference and the increased pressure difference between the common bile duct(CBD)and the main pancreatic duct(MPD),as well as the gravitational effect(position),strongly impacted PBR,while the viscosity of bile and pancreatic juice had a weaker influence.Additionally,an inequality incorporating these risk factors was developed for the evaluation of whether reflux occurs.Conclusions:Numerical simulation can be used to describe the reflux flow field,offering the possibility to visualize and analyze PBR,which has the potential to significantly revolutionize the understanding of PBR and improve clinical decision-making.Future work should focus on bridging the gap between CFD and clinical practice. 展开更多
关键词 Pancreaticobiliary reflux Computational fluid dynamics
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On the dynamics and collisions of settling spheroidal particles 认领 引用 被引量：1
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作者 Xinyu Jiang Lihao Zhao Luca Brandt 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第1期49-63,共15页
In this study,we perform particle-resolved simulations of settling spheroidal particles,considering oblate and prolate spheroids and spheres,and investigate the shape effect on the particle dynamics in suspensions wit... In this study,we perform particle-resolved simulations of settling spheroidal particles,considering oblate and prolate spheroids and spheres,and investigate the shape effect on the particle dynamics in suspensions with volume fraction 1%and 5%.We first examine the single-point statistics of the translational and rotational motion of the settling particles.The horizontal velocity has a symmetrical distribution with standard deviation dependent on the particle shape.The greater horizontal velocity fluctuations of the non-spherical particles,compared to that of spheres,are attributed to the horizontal drift of settling spheroids with oblique orientations induced by the fluid-particle and particle-particle interactions.The fluctuation of particle vertical velocity,instead,is skewed under the effect of wake-induced hydrodynamic interactions.Further,we explore the particle pair statistics,which demonstrate the formation of column-like particle micro-structures for the lowest volume fraction considered.This clustering is more pronounced for spheroidal particles than spheres,due to the stronger attractions among vertically-aligned settling spheroids.Moreover,the particle pair statistics are directly related to the collision rate among the dispersed particles.The local accumulation of oblate/prolate spheroids serves as the major mechanism to promote the particle-particle collisions in dilute suspensions. 展开更多
关键词 Particle sedimentation Dynamics Collision rate Immersed boundary method
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Influence mechanism of pore structure evolution on oxygen consumption dynamics during low-temperature oxidation of igneous metamorphic coal 认领 引用 被引量：1
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作者 Xu Shao Botao Qin +5 位作者 Quanlin Shi Ziwei Li Bao Qu Shibo Xu Junyu Wang Mingyue Weng 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2026年第3期553-572,共20页
In igneous-intruded coal seams,coal undergoes significant metamorphism,which critically alters its pore structure and oxygen consumption dynamics,thereby elevating its spontaneous combustion tendency.This study invest... In igneous-intruded coal seams,coal undergoes significant metamorphism,which critically alters its pore structure and oxygen consumption dynamics,thereby elevating its spontaneous combustion tendency.This study investigates the specific surface area,pore volume,structure complexity/connectivity,heterogeneity/local features of pore size distribution,and oxygen consumption dynamics of igneous metamorphic coal through N2/CO2 isothermal adsorption tests and low-temperature oxidation experiments,and elucidates the influence mechanisms of pore structure evolution on oxygen consumption dynamics during low-temperature oxidation.With increasing metamorphic degree,igneous metamorphic coal exhibits a more pronounced reduction in specific surface area during oxidation,while the increase in structure complexity due to coal-oxygen reactions is suppressed.Thermally metamorphic coal demonstrates accelerated oxygen consumption,with oxidation amplifying the difference in reaction rates compared to raw coal.Key mechanisms include oxidation-induced reduction in mesopore complexity and micropore volume,decreased dominance of small-pore-volume apertures,and increased heterogeneity,collectively leading to a lower half-oxygen-consuming temperature and steeper oxygen consumption curves.Simultaneously,increased pore volume/complexity and reduced uniformity/connectivity act synergistically to enhance oxygen consumption capacity,highlighting the coupling between pore structure evolution and oxidation behavior in igneous metamorphic coal.This study provides theoretical insights into the pore-oxygen coupling mechanisms governing coal spontaneous combustion in igneous intrusion areas. 展开更多
关键词 Igneous metamorphic coal Thermal metamorphism Low-temperature oxidation Pore structure Oxygen consumption dynamics
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Coupled computational fluiddynamics–discrete-element method investigation of soil contact erosion under cyclic hydraulic loading:A multiscale perspective 认领 引用
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作者 Xianfeng Diao Guoqing Cai +3 位作者 Tao Liu Peiyun Zhang Yanlin Su Bangzheng Rao 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第6期4812-4830,共19页
Tidal waves,intermittent rainfall,and fluctuations in water levels,which create cyclic hydraulic gradients,can exacerbate the migration of fine particles within soils and lead to deterioration in stability.However,mac... Tidal waves,intermittent rainfall,and fluctuations in water levels,which create cyclic hydraulic gradients,can exacerbate the migration of fine particles within soils and lead to deterioration in stability.However,macroscale experimental methods struggle to capture the microscopic deformations that occur during seepage-induced erosion.Therefore,this study,which is based on the coupled computational fluid dynamics–discrete element method(CFD–DEM)coupling method,investigates the contact mechanical mechanisms that induce macroscopic deformation under cyclic hydraulic gradients by considering the effects of different amplitudes and frequencies.The results show that the erosion mass of fine particles increases in a stepwise manner,with a multipeak variation in the erosion rate,and both the erosion amount and intensity are greater under constant gradient conditions.Fine particles erode primarily near the contact surface and,after migration,accumulate mainly in the coarse particle layers close to the contact surface.Increasing the amplitude and frequency of the cyclic hydraulic gradient leads to more fine particle blockages within the coarse particle layer.The cyclic hydraulic gradient causes the contact force chain network to repeatedly break and reorganize,reducing the shear strengths of the soil and resulting in more pronounced anisotropy in the contact force distribution. 展开更多
关键词 Computational fluid dynamics–discrete element method(CFD–DEM)coupling Contact erosion Cyclic hydraulic gradients Macroscopic deformation Micromechanism
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Genotypic and virulence dynamics of Phytophthora infestans populations in southwestern China 认领 引用
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作者 Xinjie Zhang Jinbin Wu +12 位作者 Xiao Wang Fan Zhang Lina Yang Luyao Wang Yaoyao Wu Zhenzhen Wang Weilin Chen Guoyu Yin Shengping Song Mingqing Dang Juan Zeng Han Chen Suomeng Dong 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2026年第8期3307-3317,共11页
The oomycete pathogen Phytophthora infestans causes late blight disease that severely reduces potato production worldwide.Monitoring the genotypic and virulence dynamics of P.infestans populations is vital for managem... The oomycete pathogen Phytophthora infestans causes late blight disease that severely reduces potato production worldwide.Monitoring the genotypic and virulence dynamics of P.infestans populations is vital for management of late blight.Phytophthora infestans populations in southwestern China diversify in genotypes and virulence,but the most recent status of these populations remains elusive.In this study,218 isolates collected from six locations in southwestern China from 2019 to 2022 were analyzed for genotypic and virulence dynamics as well as effective management strategies.Phylogenetic analysis of simple sequence repeats-classified multi-locus genotypes(MLGs)revealed that these populations comprise three lineages,of which the EU lineage is dominant.These populations had overcome the resistance mediated by R3a,R3b and Rpi-blb3 and had an increased trend in overcoming the resistance mediated by Rpi-blb2,R8,Rpi-blb1 and Rpi-vnt1.1.The EU lineage consisted of 19 MLGs and the predominant genotype MLG24 significantly contributed to the pathotypic diversity of the EU lineage.In addition,two independent MLG24 isolates,CQ-22-16-1 and CQ-22-20-1,overcame the resistance mediated by all seven resistance genes and were virulent on 30 potato cultivars.Notably,two Solanum candolleanum relatives were highly resistant to these two highly virulent isolates.Furthermore,these two isolates could be controlled by three fungicides.In summary,this study elucidates the genotypic and virulence dynamics of P.infestans populations in southwestern China and provides valuable insights into effective control measures. 展开更多
关键词 potato Phytophthora infestans genotypic dynamics virulence dynamics
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The prognostic significance of prostate-specific antigen dynamics during abiraterone therapy in patients with high-risk metastatic hormone-sensitive prostate cancer 认领 引用
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作者 Qian Wang Ming Zhang +8 位作者 Qi-Yu Zhu Hong Zeng Jin-Dong Dai Ke Huang Si-Cheng Wan Yi-Fu Shi Xing-Ming Zhang Hao Zeng Peng-Fei Shen 《Asian Journal of Andrology》 SCIE CAS CSCD 2026年第3期304-309,共6页
To evaluate the prognostic significance of prostate-specific antigen(PSA)decline depth and duration in patients with high-risk metastatic hormone-sensitive prostate cancer(mHSPC)undergoing abiraterone treatment.We ret... To evaluate the prognostic significance of prostate-specific antigen(PSA)decline depth and duration in patients with high-risk metastatic hormone-sensitive prostate cancer(mHSPC)undergoing abiraterone treatment.We retrospectively analyzed data from 153 high-risk patients with mHSPC receiving first-line abiraterone therapy.Patients were stratified based on PSA dynamics during treatment.Kaplan–Meier survival analysis and Cox proportional hazards regression were used to assess the associations between PSA decline patterns,PSA progression-free survival(PSA-PFS),radiographic PFS(rPFS),and overall survival(OS).Among the 153 patients,85 exhibited PSA nadir4 ng ml−1.During abiraterone treatment,PSA nadir<0.2 ng ml−1 was significantly associated with improved median PSA-PFS(51.0 months vs 18.5 months vs 6.9 months,P<0.0001),median rPFS(52.0 months vs 24.3 months vs 10.3 months,P<0.0001),and median OS(not reached vs 48.5 months vs 28.1 months,P<0.0001)compared with PSA nadir≥0.2 ng ml-1 and<4 ng ml-1,and PSA nadir≥4 ng ml-1.In the cohort with PSA nadir<0.2 ng ml−1,achieving PSA<0.2 ng ml−1 within 6 months and maintaining this level for over 10 months significantly enhanced clinical outcomes,as evidenced by median PSA-PFS(not reached vs 26.9 months,P<0.0001),median rPFS(not reached vs 27.5 months,P<0.0001),and median OS(not reached vs 44.4 months,P<0.0001).Cox regression analysis revealed that achieving PSA<0.2 ng ml−1 within 6 months post-treatment and sustaining this level for over 10 months are independent prognostic factors.In high-risk patients with mHSPC receiving first-line abiraterone,sustained PSA suppression is a key indicator of therapeutic response.The rate,depth,and duration of PSA decline are critical prognostic factors. 展开更多
关键词 dynamics high-risk prognostic prostate cancer PSA
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Dynamics of a two-disk dynamo loaded with a dual neuron circuit and its application 认领 引用
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作者 Fuqiang WU Ying XU +1 位作者 Huimin QI Jun MA 《Journal of Zhejiang University-SCIENCE A》 SCIE EI CAS CSCD 2026年第7期762-778,I0057-I0060,共17页
Constructing a neuromorphic electromechanical system based on a flexible memristor is of great significance for the development of biomimetic electrical-mechanical transverters.A bioinspired electromechanical system c... Constructing a neuromorphic electromechanical system based on a flexible memristor is of great significance for the development of biomimetic electrical-mechanical transverters.A bioinspired electromechanical system can perform real-time energy-efficient processing of multimodal signals,including electrical activities and mechanical motions.Here,we propose a bioinspired electromechanical system composed of a two-disc dynamo driven by a dual integrate-and-fire neuron.A memristive system exists in the bioinspired electromechanical system,as observed in the current-voltage relationship.The neuromorphic electromechanical model can exhibit a multiscroll hidden attractor by adjusting a controllable parameter.Complex chaotic behaviors have been demonstrated by numerical simulations,including two-parameter bifurcation,Lyapunov exponents,and phase diagrams.Finally,the applicability of a chaotic encryption scheme is successfully implemented on a neuromorphic electromechanical system. 展开更多
关键词 Nonlinear dynamics Neuron Chaotic model Electromechanical system Memristor Encryption
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Trajectories of vegetation dynamics and their driving factors across China Ecosystem Research Network:A long-term assessment(2000–2024) 认领 引用
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作者 ZHANG Shuyi JIN Ziwen +7 位作者 CI Mengyao ZENG Ke WANG Yue TANG Hanxin ZHANG Rui CAI Chaolin CAO Xianzhong LIU Min 《Journal of Geographical Sciences》 SCIE CSCD 2026年第5期1059-1077,共19页
Long-term monitoring of vegetation dynamics is essential for assessing ecosystems resilience and responses to climate change.The China Ecosystem Research Network(CERN)is a national long-term observation network that p... Long-term monitoring of vegetation dynamics is essential for assessing ecosystems resilience and responses to climate change.The China Ecosystem Research Network(CERN)is a national long-term observation network that provides an ecological baseline across China’s major ecosystems.This study analyzed vegetation trends and their driving factors from2000 to 2024 across 34 CERN field stations and their surrounding areas.An intercomparison of multiple NDVI products revealed substantial inconsistencies.MODIS NDVI exhibited superior temporal stability and spatial coherence and was therefore selected for long-term analysis.The mean NDVI at CERN stations(0.419)was 37.8%higher than the national average(0.304),and showed significantly faster greening trends(0.022/10 a)compared to suburban(0.013/10 a)and rural(0.017/10 a)areas,reflecting effective vegetation restoration and stable ecosystem management.Vegetation changes at CERN field stations were predominantly governed by climatic rather than anthropogenic factors.Among different ecosystem types,air temperature(AT),sunshine duration(SD),and relative humility(RH)were the dominant drivers in farmland,forest,and wetland.For grassland,AT and SD were the main drivers,whereas AT and RH exerted the strongest influence in the desert ecosystem.These findings confirm the representativeness of CERN stations and underscore the predominant role of climatic factors in shaping long-term vegetation trajectories across China’s diverse ecosystems. 展开更多
关键词 vegetation dynamics NDVI climate change human activities CERN China
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Nuclear magnetic resonance-guided Monte Carlo/molecular dynamics structure inference for amorphous solids 认领 引用
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作者 Kangren Kong Zaiqiang Ma +2 位作者 Yu Yin Zhaoming Liu Ruikang Tang 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2026年第3期10-16,共7页
Amorphous solids,which do not possess a long-range order,hold great promise in mechanical,optical,chemical,and other properties,and have also been revealed as critical biomineralization precursors.However,funda-mental... Amorphous solids,which do not possess a long-range order,hold great promise in mechanical,optical,chemical,and other properties,and have also been revealed as critical biomineralization precursors.However,funda-mental questions about their three-dimensional(3D)atomic structure remain challenging due to the long-range disorder.Conventional protocols probe such molecular structures through scattering or real-space imaging.The former provides ensemble-averaged data that masks local structural deviations,while the latter is hampered by the electron-beam sensitivity of materials.Nevertheless,based on distance-sensitive heteronuclear coupling,rotational echo double resonance(REDOR),a specialized solid-state nuclear magnetic resonance(NMR)mea-surement,is efficient in detecting local deviations and usually nondestructive.Here,using amorphous calcium carbonate/phosphate Ca(CO3)x(PO4)2(1-x/3)(0<x<1,CaCPs)solids synthesized by ion cross-linking as an example,we develop a nondestructive method to reveal local deviations of amorphous ionic solids by combining REDOR,Monte Carlo(MC),and molecular dynamic(MD)simulation.Briefly,MC simulations generated atomic structures with heterogeneous medium-range spatial apportionment of ions,and MD simulations relaxed the initial configuration to rationalize short-range order.Then,theoretical REDOR decay curves of MC/MD-generated structures were compared with experimental values to check the medium-range order.We revealed that there is heterogeneous medium-range spatial apportionment of anions in CaCPs.Since solid-state NMR is applicable to nearly all spin-active materials,this methodology offers a versatile alternative for resolving the atomic structure of amorphous solids. 展开更多
关键词 REDOR Amorphous material Molecular dynamics Calcium carbonate Calcium phosphate
Unbiased Segmentation and Multifeature Classification of Cortical Neuronal Activity Reveals Complex Dynamics Under Anesthesia 认领 引用
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作者 Zilin Wang Ao Li +6 位作者 Guihua Xiao Xingzheng Gu Zhilei Wang Shuting Guo Rujin Zhang Chaowei Zhuang Jiangbei Cao 《Neuroscience Bulletin》 SCIE CAS CSCD 2026年第3期491-504,共14页
Cortical layer 2/3 plays a pivotal role in regulating perception and consciousness.However,the effects of anesthetic agents on the dynamic activity patterns in this layer remain poorly understood.This study examined h... Cortical layer 2/3 plays a pivotal role in regulating perception and consciousness.However,the effects of anesthetic agents on the dynamic activity patterns in this layer remain poorly understood.This study examined how neuronal activity in cortical layer 2/3 dynamically changes under anesthesia.Using high-resolution wide-field microscopy,we performed whole-brain synchronous imaging of layer 2/3 neuronal activity in mice.Using these recordings,we performed an unbiased segmentation of the awake,anesthesia,and recovery stages and classified neurons into three categories according to their activity features.Our findings revealed the characteristics of cortical dynamics under anesthesia,including a rebound effect during recovery and nonlinear changes in neuronal activity.We also confirmed the consistent and uniform characteristics of superficial cortical layer activity under anesthesia.These results increase the understanding of cortical dynamics and provide a theoretical basis for improving clinical monitoring techniques and protocols. 展开更多
关键词 Anesthesia Layer 2/3 Wide-field imaging Neuronal dynamics Clustering
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In-situ tracking of organic reaction dynamics:an infrared-temperature dual sensing approach using a single chalcogenide fiber 认领 引用
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作者 XINXIANG HUANG SHILIANG KANG +4 位作者 YANQING FU LINLING TAN CHENGWEI GAO SHIXUN DAI CHANGGUI LIN 《Photonics Research》 SCIE EI CAS CSCD 2026年第6期2418-2427,共10页
Precise control over organic reaction dynamic requires in-situ insight into temperature and concentration variations.However,conventional detection strategies,often relying on off-line or decoupled methods,suffer from... Precise control over organic reaction dynamic requires in-situ insight into temperature and concentration variations.However,conventional detection strategies,often relying on off-line or decoupled methods,suffer from delayed responses and poor temporal synchronization.Herein,we propose a bifunctional single-fiber sensor based on Ge5As25Se30Te40 chalcogenide glass,which seamlessly integrates fiber evanescent wave spectroscopy for chemical fingerprinting identification with a thermoresistive effect for thermal sensing.It exhibits exceptional performance with a rapid temperature response(~2.6 s)and a high temperature sensitivity(jTCRj~4.07%K-1).Validated through the in-situ monitoring of ethyl butyrate synthesis,the single-fiber sensor effectively tracked reaction evolution and thermal distinctness,providing reliable guidance for process optimization and control.With its label-free detection,structural simplicity,and high sensitivity,this proposed strategy represents a robust process analytical technology tool for monitoring complex organic reactions. 展开更多
关键词 chemical fingerprinting identification situ tracking fiber evanescent wave spectroscopy thermoresistive effect infrared temperature dual sensing detection strategiesoften precise control organic reaction dynamic organic reaction dynamics
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Computational Analysis of Autonomous Underwater Vehicles(AUVs)Structural Dynamics and Impact Forces During High Speed Water Entry 认领 引用
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作者 YU Yi-lan PAN Guang +1 位作者 SHI Yao HUANG Qiao-gao 《China Ocean Engineering》 SCIE EI CSCD 2026年第3期507-520,共14页
Understanding the structural response of Autonomous Underwater Vehicles(AUVs)during water entry is essential for ensuring operational safety and reliability.This paper introduces a bidirectional fluid-structure coupli... Understanding the structural response of Autonomous Underwater Vehicles(AUVs)during water entry is essential for ensuring operational safety and reliability.This paper introduces a bidirectional fluid-structure coupling numerical algorithm to analyze the structural response characteristics of an AUV during water entry at various speeds and angles.The numerical method’s accuracy is verified through experimental data.The investigation focuses on the water entry process within the velocity range of 50 to 200 m/s and entry angles between 60°and 90°.The study examines the influence of structural position,entry velocity,and entry angle on the structural response,while analyzing stress and strain at specific locations on the circular end face,cylindrical side,and circular tail surface of the AUV.The findings demonstrate that at entry speeds exceeding 100 m/s,the structure undergoes strain,with entry velocity exhibiting a more pronounced effect on axial force compared with entry angle.A reduced entry angle decreases the initial water contact duration and minimizes stress concentration.These results provide significant theoretical foundations for AUV structural design. 展开更多
关键词 AUV structural dynamics stress propagation water entry transmedia FSI
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Sub-inhibitory antibiotics reshape resistance dynamics in cyanobacteria-dominated waters 认领 引用
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作者 Xuefei Wu Hualong Sun +3 位作者 Gang Wang Li Liu Mengqi Zheng Guowei Chen 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第7期132-141,共10页
Cyanobacteria are competent hosts for antibiotic resistance genes,influencing the spread of bacterial resistance through their complex interactions within aquatic environments.However,the coevolution of antibiotic res... Cyanobacteria are competent hosts for antibiotic resistance genes,influencing the spread of bacterial resistance through their complex interactions within aquatic environments.However,the coevolution of antibiotic resistance between cyanobacteria and bacteria under sub-inhibitory antibiotic stresses remains unclear.To bridge this knowledge gap,we investigated the effects of Microcystis aeruginosa on modulating bacterial resistance evolution in aquatic ecosystems exposed to sub-inhibitory antibiotics.Results show that cyanobacteria reduced the abundance of antibiotic resistance bacteria(ARB) by 62 % to 93 % in antibiotic-free conditions and by up to 80 % under sub-inhibitory antibiotic concentrations.The concurrence of cyanobacteria and antibiotics significantly alter microbial community compositions,with Proteobacteria emerging as the dominant population(51 %-66 %) and Bacteroidota proliferating by 8.7-fold,alongside a significant enrichment of metabolism-related and pathogenic genes(p <0.05).Redundancy analysis revealed that ARB prevalence was positively correlated with the abundances of Proteobacteria and Bacteroidota,but negatively correlated with Cyanobacteria.Our findings suggest that cyanobacteria may reduce the spread of bacterial resistance both in antibiotic-free and sub-inhibitory antibiotic environments,by reshaping population interactions.These insights are crucial for evaluating the risk of antibiotic-driven bacterial resistance spread in cyanobacteria-rich environments and are vital for the protection and assessment of aquatic environmental quality. 展开更多
关键词 Aquatic environments Bacterial resistance Commensal cyanobacteria Population dynamics Sub-inhibitory antibiotics
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Phonon bottleneck effect due to finite shrinking gap revealed by high-pressure ultrafast dynamics 认领 引用
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作者 Yanling Wu Q.Wu +9 位作者 X.Yin Y.X.Huang Takeshi Nakagawa Z.Y.Tian Fei Sun Q.M.Zhang Jun Chang Ho-kwang Mao Yang Ding Jimin Zhao 《Chinese Physics B》 SCIE EI CAS CSCD 2026年第3期137-142,共6页
High-pressure ultrafast dynamics has been recently developed,enabling the exploration of non-equilibrium properties of various quantum materials under high pressure.Particularly,by investigating the pressure dependenc... High-pressure ultrafast dynamics has been recently developed,enabling the exploration of non-equilibrium properties of various quantum materials under high pressure.Particularly,by investigating the pressure dependence of time-resolved ultrafast dynamics,we have discovered a pressure-induced phonon bottleneck effect(PBE).To date,all reported PBEs are due to fully closed gaps,which was reflected in the simultaneous characteristic changes in both amplitude and lifetime of the phonon-phonon scattering slow relaxation component.However,as reflected through its connection to Euler disk,incompletely closed gaps can also induce PBEs.In this work,we report the first PBE due to a finite shrinking gap.As is known,it is challenging to directly observe high-pressure-induced variations in electronic band gaps due to the diamond anvil cell.Here,by investigating Sr2IrO4in our previous work,we obtain an empirical formula for the pressure-induced energy gap variation at room temperature.Our quantitative analysis shows that the gap is finite shrinking rather than fully closed. 展开更多
关键词 phonon bottleneck effect ultrafast dynamics high pressure ultrafast spectroscopy finite gap
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Fixed-Time Zeroing Neural Dynamics for Adaptive Coordination of Multi-Agent Systems 认领 引用
18
作者 Cheng Hua Xinwei Cao +1 位作者 Jianfeng Li Shuai Li 《CAAI Transactions on Intelligence Technology》 SCIE EI CSCD 2026年第1期267-278,共12页
This paper presents an adaptive multi-agent coordination(AMAC)strategy suitable for complex scenarios,which only requires information exchange between neighbouring robots.Unlike traditional multi-agent coordination me... This paper presents an adaptive multi-agent coordination(AMAC)strategy suitable for complex scenarios,which only requires information exchange between neighbouring robots.Unlike traditional multi-agent coordination methods that are solved by neural dynamics,the proposed strategy displays greater flexibility,adaptability and scalability.Furthermore,the proposed AMAC strategy is reconstructed as a time-varying complex-valued matrix equation.By introducing a dynamic error function,a fixed-time convergent zeroing neural network(FTCZNN)model is designed for the online solution of the AMAC strategy,with its convergence time upper bound derived theoretically.Finally,the effectiveness and applicability of the coordination control method are demonstrated by numerical simulations and physical experiments.Numerical results indicate that this method can reduce the formation error to the order of 10-6within 1.8 s. 展开更多
关键词 fixed-time convergence multi-agent coordination robotics zeroing neural dynamics
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Comparative analysis of windbreak configurations for unloaded gondola train cars under crosswinds based on computational fluid dynamics and multi-body dynamics 认领 引用
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作者 Jiayuan SONG Wentao HE +1 位作者 Yanlin HU Kaiyun WANG 《Journal of Zhejiang University-SCIENCE A》 SCIE EI CAS CSCD 2026年第1期26-42,共17页
Understanding the aerodynamic and dynamic characteristics of unloaded freight trains in crosswinds is pivotal for ensuring their operational safety and reliability.The dynamic performance of unloaded gondola cars unde... Understanding the aerodynamic and dynamic characteristics of unloaded freight trains in crosswinds is pivotal for ensuring their operational safety and reliability.The dynamic performance of unloaded gondola cars under varying windbreak heights is therefore investigated in this study,revealing distinct differences in lateral stability and safety indicators,and enabling the determination of an optimal windbreak height.A 3D unsteady aerodynamic model was developed using the improved delayed detached eddy simulation(IDDES)method and an overset numerical mesh.Also leveraging a multi-body dynamics(MBD)model of a three-wagon freight car configuration,we investigate time-averaged aerodynamic forces,transient flow field distributions,and nonlinear dynamic responses.Parametric analyses reveal a non-monotonic relationship between the height of the windbreak and the stability of the train.A windbreak with a critical height of 2 m(0.74 relative to the car body height)results in 76%,64%,and 81%lower values of the derailment coefficient CD,wheel unloading ratio R,and overturning coefficient CO,respectively.Notably,when the height of the windbreak exceeds 2 m,vortices within the gondola induce an adverse pressure coefficient distribution(Cp=−2.17)on the leeward internal wall,intensifying the lateral force and overturning moment.Furthermore,frequency-domain analysis reveals that the lateral sway and overturning vibration mode are associated with low-frequency(1.61 Hz)lateral vibrations under crosswind conditions.This study provides a theoretical foundation for the design and optimization of railway windbreaks. 展开更多
关键词 Crosswind Train gondola Unsteady aerodynamics Dynamic response Train safety Windbreaks
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Influence of CaO-SiO2-Al2O3-MgO slag structure on dissolution behavior of Al2O3:a molecular dynamics simulation 认领 引用
20
作者 Yi-Hong Li Ming-Ming Lu +4 位作者 Rui Wang Dong Wang Xin Hu Peng Zhang Qiang Zhu 《Journal of Iron and Steel Research International》 SCIE EI CSCD 2026年第1期110-124,共15页
The structural changes in the CaO-SiO2-Al2O3-MgO slag system with varying CaO contents were investigated through molecular dynamics(MD)simulations,and its effect on the dissolution behavior of alumina inclusi... The structural changes in the CaO-SiO2-Al2O3-MgO slag system with varying CaO contents were investigated through molecular dynamics(MD)simulations,and its effect on the dissolution behavior of alumina inclusions was characterized by the Kullback-Leibler(KL)divergence.The slag structure analysis revealed that the[AlO]tetrahedral structure was the primary network structure in the slag.With increasing the CaO content,the non-bridge oxygen(NBO)content in the slag structure increases,and the bridge oxygen(BO)content decreases,thereby reducing the complexity of the slag network structure.Raman spectroscopy detection verifies the results of the MD simulations.The results indicated that the dissolution rate of alumina inclusions accelerates with increasing the CaO content in the slag,owing to the reduced complexity of the slag network structure and the enhanced interatomic interactions.The simulation results for the dissolution of alumina inclusions were consistent with theoretical calculations based on the slag inclusion capacity and the dimensionless dissolution rate of inclusions.Radial distribution function analysis demonstrated that the interaction between atoms in the slag system and alumina inclusions strengthens,increasing the dissolution rate of alumina inclusions.The[AlO6]octahedral structure of the alumina inclusions is disrupted,forming BO structures,which in turn enhances the complexity of the slag network structure,slowing the dissolution rate of alumina inclusions.In contrast,the slag system with a higher CaO content has a relatively simpler network structure,promoting faster alumina inclusion dissolution. 展开更多
关键词 Molecular dynamics simulation Slag structure Dissolution behaviour Alumina inclusion Dissolution rate
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