Objectives This study aimed to develop a competency-oriented ecological education model and evaluate the feasibility and preliminary outcomes of its implementation for enhancing evidence-based practice competencies am...Objectives This study aimed to develop a competency-oriented ecological education model and evaluate the feasibility and preliminary outcomes of its implementation for enhancing evidence-based practice competencies among undergraduate nursing students.Methods An ecological education model was developed based on educational ecology theory and the input–environment–output(IEO)theoretical framework,and implemented from 2019 to 2024.The model integrated three core components:a four-year progressive competency development pathway(ranging from evidence-based thinking in year one to comprehensive practice application in year four);a three-tier ecological environment(comprising physical,classroom,and practice environments that incorporates six best practice spotlight organization guidelines into eight core courses);and multidimensional practice platforms,including health science communication and guideline translation.The reform was conducted at a nursing school of a double first-class university in Beijing,China.A naturalistic longitudinal cohort design was employed,which included 1,223 undergraduate nursing students at baseline(2019,pre-reform)and 1,237 at post-implementation(2024).A convergent parallel mixed-methods approach was used to evaluate the implementation outcomes.Quantitative data on academic performance and innovation outcomes were collected at both time points,baseline and post-implementation.Semi-structured interviews with 18 students were conducted to supplement the exploration of their learning experiences.Results Academic engagement increased from 78.5%to 97.3%,evidence-based graduation theses rose from 18.6%to 30.0%,and innovation and entrepreneurship projects increased from 40 to 150.Qualitative analysis revealed four themes and twelve subthemes,revealing enhanced critical appraisal skills(88.9%),evidence synthesis capabilities(94.4%),and professional confidence(83.3%)among students.Integrated mixed-methods analysis revealed stage-specific characteristics across academic years:a complementarity pattern in Year 1(foundational awareness building),a convergence pattern in Years 2–3(systematic competency construction),an expansion pattern during the Year 3 transition(role adaptation challenges),and a convergence pattern in Year 4(comprehensive transformation and professional confidence enhancement).Conclusions This feasibility study demonstrated that the ecological education model could be successfully implemented in undergraduate nursing education with promising preliminary outcomes.This study provides an initial framework for nursing education innovation and establishes foundational evidence warranting future rigorous controlled studies to examine the model’s effectiveness.展开更多
Reflexology has recently gained attention as a complementary therapy, but existing evidence on its effectiveness for blood pressure (BP) remains scattered and inconsistent. This study aimed to synthesize and criticall...Reflexology has recently gained attention as a complementary therapy, but existing evidence on its effectiveness for blood pressure (BP) remains scattered and inconsistent. This study aimed to synthesize and critically evaluate published systematic reviews and meta-analyses examining the impact of reflexology on BP. A comprehensive search was conducted in PubMed, Scopus, Web of Science, and Epistemonikos up to unti August 25, 2025. Eligible studies included systematic reviews and meta-analyses assessing the effects of reflexology on adult systolic BP and diastolic BP. Methodological quality was evaluated using the A MeaSurement Tool to Assess Systematic Reviews 2 tool, and overlap among primary studies was measured using the Corrected Covered Area (CCA) index. The review process followed the Preferred Reporting Items for Overviews of Reviews checklist. Nine reviews (five meta-analyses and four systematic reviews), including 43 primary studies, were identified.Meta-analytic results showed considerable heterogeneity, with findings ranging from no significant effect to mild or moderate BP reduction after reflexology. All included reviews were rated as critically low quality, mainly due to inadequate assessment of publication bias and insufficient evaluation of risk of bias in primary studies. Primary study overlap was low (CCA = 3.77%). The current evidence on the efficacy of reflexology for BP control remains uncertain and low in certainty. While reflexology appears safe and may contribute to small BP reductions, the evidence is insufficient to support strong clinical recommendations. Robust, large-scale randomized controlled trials and methodologically sound systematic reviews are needed to clarify the role of reflexology in hypertension management.展开更多
BACKGROUND With an aging society,older patients undergoing cholecystectomy often have multiple chronic diseases and require long-term multi-medication.Medication complexity significantly increases the risk of medicati...BACKGROUND With an aging society,older patients undergoing cholecystectomy often have multiple chronic diseases and require long-term multi-medication.Medication complexity significantly increases the risk of medication errors and adverse reactions,and effective nursing interventions are urgently required to ensure medication safety.AIM To investigate the efficacy of evidence-based nursing practices in mitigating polypharmacy risks among Suzhou Municipal Hospital Road Front Yard Area,thereby providing clinical guidance.METHODS The sixty older patients who underwent cholecystectomy between September 2024 and September 2025 treated with polypharmacy were enrolled.Using random number tables,hey were divided into study and control groups(n=30 each),who received routine medication nursing and evidence-based nursing,respectively.Pre-intervention and post-intervention comparisons were made between groups for medication knowledge,competence,and adherence scores.The incidences of duplicate medications,missed doses,self-discontinuation,unauthorized alterations,schedule changes,and adverse reaction rates assessed potential medication risks.RESULTS Both the study and control groups showed significant increases in medication knowledge,management competence,and adherence scores after intervention(all P<0.05).The study group had higher post-intervention scores(medication knowledge:87.29±5.09 vs 70.62±5.38;medication management competence:63.22±3.11 vs 56.19±4.08;medication adherence:7.13±1.04 vs 6.05±1.03,all P<0.05).The incidence of duplicate medication,missed doses,self-discontinuation,unauthorized dose alterations,and schedule modifications decreased in both groups post-intervention(all P<0.05),with lower rates in the study group(duplicate medication:13.33%vs 30.0%;missed doses:10.0%vs 26.67%;all P<0.05).The study group had a lower adverse reaction rate(3.33%vs 26.67%,P<0.05)and more patients with potential medication hazard level 0(83.33%vs 53.33%),while fewer patients had level 2 and 3 hazards(3.33%vs 16.67%and 0%vs 10.00%,respectively;all P<0.05).CONCLUSION Evidence-based nursing for polypharmacy risks in older adults undergoing cholecystectomy can enhance medication awareness,improve management and adherence,reduce adverse behaviors,and lower adverse reactions and hazard levels.展开更多
Objective This study aimed to explore the facilitators of and barriers to the clinical translation of evidence-based nursing guidelines.Methods A convergent mixed-methods study design.First,206 nurses from 12 hospital...Objective This study aimed to explore the facilitators of and barriers to the clinical translation of evidence-based nursing guidelines.Methods A convergent mixed-methods study design.First,206 nurses from 12 hospitals were selected as study participants,and the Chinese version of the Organizational Readiness to Change Assessment(ORCA)scale was administered to assess the current readiness for guideline implementation.Subsequently,for the qualitative study,purposive sampling was used to select 15 nurses from the quantitative study sample for semistructured interviews.The framework analysis method was applied to code the transcribed texts using the Consolidated Framework for Implementation Research(CFIR),and thematic analysis was employed to identify facilitators and barriers to guideline implementation.Finally,all facilitating and barrier factors were systematically synthesized,and implementation strategies were matched using the Consolidated Framework for Implementation Research–Expert Recommendations for Implementing Change(CFIR–ERIC)tool.Results The organizational change readiness score was moderate-to-high(248.77±33.35).The quantitative study identified 25 facilitating factors(such as the scientific rigor of guideline implementation and a positive departmental culture)and 16 barriers(including insufficient resources to address patient awareness or needs and inadequate communication among team members).The qualitative study identified 25 facilitating factors(such as high self-efficacy in evidence-based practice and leadership support)and 11 barriers(such as implementation complexity and resource constraints).From a mixed-methods analysis,the top three barriers were identified as a lack of incentives,insufficient resources,and interdepartmental communication barriers.Based on the CFIR-ERIC mapping,implementation recommendations targeting the main barriers were identified,including tailoring implementation strategies,modifying incentive mechanisms or compensation structures,and establishing communication networks among team members.Conclusion This study systematically revealed,through a mixed-methods approach,the current status of nurses’readiness to participate in guideline implementation in China,as well as the facilitating factors and barriers.In the future,targeted strategies should be developed based on the identified barriers to promote the sustained implementation of guidelines.展开更多
Objectives We aimed to describe the implementation process and provide a baseline characterization of suicidal behavior during the first year of implementing the Registered Nurses’Association of Ontario(RNAO)Best Pra...Objectives We aimed to describe the implementation process and provide a baseline characterization of suicidal behavior during the first year of implementing the Registered Nurses’Association of Ontario(RNAO)Best Practice Guideline(BPG)for suicide prevention in a tertiary occupational hospital in Santiago,Chile.Methods A cross-sectional descriptive study was guided by the Knowledge-to-Action(KTA)framework.The implementation process included:1)assessment of the local context;2)adaptation of 26 RNAO BPG recommendations through the first four phases of the KTA cycle;and 3)use of institutional data from April 2024 to April 2025 to establish a baseline of suicidal behavior.Data sources included Emergency Department(ED)consultations,hospital admissions,liaison psychiatry referrals,patient safety reports,and staff training records.Data were analyzed using descriptive statistics.Results The preliminary assessment identified variable levels of compliance with the RNAO BPG recommendations,with 9 fully met,12 partially met,and 4 unmet.Contextual analysis revealed key barriers and facilitators at the individual,team,and organizational levels,and identified priority stakeholders.Based on these findings,context-adapted strategies were developed,including protocol standardization,staff training,structured referral pathways,and environmental safety measures.Institutional data showed 7,936 ED consultations,of which 577(7.3%)involved suicidal behavior.Among 368 admitted patients with primary mental health diagnoses,336(91.3%)were linked to suicide risk.Liaison psychiatry documented 7 cases from medical-surgical wards,while patient safety records identified three suicide-related sentinel events associated with mild to moderate harm.Conclusions Implementation demonstrated that evidence-based nursing,guided by the KTA framework,supports standardized detection and management of suicide risk.These findings provide an initial characterization of suicidal behavior in an occupational health setting and underscore the importance of context-adapted strategies,continuous training,and institutional cultural change to support implementation.展开更多
Objective:To describe the implementation of evidence-based practice(EBP)and identify the associated factors among clinical nurses working at an oncology hospital in Central Vietnam.Methods:A cross-sectional study was ...Objective:To describe the implementation of evidence-based practice(EBP)and identify the associated factors among clinical nurses working at an oncology hospital in Central Vietnam.Methods:A cross-sectional study was conducted with 190 clinical nurses recruited from an oncology hospital in Central Vietnam.The self-administered Evidence-Based Practice Questionnaire(EBPQ)was employed to assess the nurses'knowledge/skills,attitudes,and implementation of EBP.Data analysis utilized descriptive statistics,the Mann-Whitney test,the Kruskal-Wallis test,and Spearman's rho correlation.Results:The mean total score for EBP implementation among the nurses was 29.52(SD=7.14)out of 42 scores.The most frequently undertaken activity was sharing evidence with colleagues,whereas finding relevant evidence was the least performed.The level of EBP implementation significantly varied based on the nurses'role types and their participation in related courses(P<0.05).Moreover,a strong positive correlation was observed between EBP implementation and both knowledge/skills(r=0.703,P<0.001)and attitudes toward EBP(r=0.536,P<0.001).Conclusions:The implementation of EBP by oncology nurses is generally moderate and is significantly positively correlated with their knowledge/skills and attitudes toward EBP.These findings underscore the importance of enhancing educational programs and facilitating suppor tive institutional policies to fur ther encourage the adoption of EBP among nurses.展开更多
Despite the established need for evidence-based practice(EBP),its implementation in nursing remainsinconsistent due to organizational,presentation,and individual barriers.Mentorship is frequently citedas a solution,ye...Despite the established need for evidence-based practice(EBP),its implementation in nursing remainsinconsistent due to organizational,presentation,and individual barriers.Mentorship is frequently citedas a solution,yet its mechanisms for bridging evidence to practice are underexplored.This studyaimed to examine how mentorship functions as a strategy to support EBP implementation.First,wediscuss how mentorship addresses nurse-related barriers by providing just-in-time coaching and rolemodeling,enabling mentors to build mentees’critical appraisal skills and clinical Second,we examine how mentorship mitigates presentation-related barriers by enabling mentors to act asknowledge brokers,translating complex evidence into accessible,conteguidance for thebedside.Third,we outline how mentorship addresses organizational or setting-related barriers byembedding EBP into formalized structures,including mentor roles,protected time,and evaluation metrics.To operationalize these mechanisms,we propose an implementation mapping frameworkthat key actors,targeted actions,and measurable outcomes while addressing structuralchallenges such as limited protected time.We conclude that formalized mentorship is essential fortransforming theoretical evidence into sustainable bedside practice and fostering a culture of excellencethat directly improves patient outcomes.展开更多
Objectives Evidence-based practice(EBP)is widely accepted as central to high-quality nursing care,yet integration into acute care settings remains uneven.Nurses play a vital role in applying evidence,but organizationa...Objectives Evidence-based practice(EBP)is widely accepted as central to high-quality nursing care,yet integration into acute care settings remains uneven.Nurses play a vital role in applying evidence,but organizational hierarchies,time constraints,and limited interprofessional collaboration often restrict their ability to lead or sustain EBP.This study explored how nurses enact,adapt,and promote EBP through interprofessional collaboration,everyday clinical leadership,and access to continuing professional development.Methods An embedded comparative case study design was used,informed by interpretive and ethnographic principles.The research was conducted across two large hospitals in England with differing leadership and governance structures.Twenty-five participants were included,consisting of nurses,nurse managers,and physicians.Data were collected over six years through 25 semi-structured interviews,60 h of non-participant observation,and review of policy and quality improvement documents.Data were analyzed using reflexive thematic analysis.Results Five key themes were identified:leadership practices and organizational support;professional identity and EBP ownership;interprofessional collaboration and communication;structural barriers and resource constraints;and capacity building through learning and feedback.Nurses enacted EBP through informal leadership,peer mentorship,and grassroots innovation.Structural barriers such as limited time,unequal access to continuing professional development,and fragmented collaboration significantly affected implementation.Conclusions Nurses play an active and sustained role in leading EBP through their relationships,clinical judgment,and commitment to care quality.However,their efforts are shaped by the broader organizational systems in which they work.Supporting interprofessional collaboration,distributed leadership,establishing EBP mentoring roles,and ensuring equitable access to continuing professional development are essential for consistent and inclusive evidence use.Hospital managers and policymakers should prioritize structural investment in team-based learning,inclusive governance and digital access.展开更多
BACKGROUND The Liver Imaging Reporting and Data System(LI-RADS)is widely used for the diagnosis of hepatocellular carcinoma,but feature scoring by radiologists is subjective and time-consuming.An urgent need exists fo...BACKGROUND The Liver Imaging Reporting and Data System(LI-RADS)is widely used for the diagnosis of hepatocellular carcinoma,but feature scoring by radiologists is subjective and time-consuming.An urgent need exists for an objective and efficient radiologist-supervised automated LI-RADS categorization system.AIM To develop an evidence-based radiologist-supervised automated LI-RADS grade 3(LR-3),4(LR-4)and 5(LR-5)categorization system(Evi-LIRADS)through quantitative feature characterization,following LI-RADS v2018.METHODS This retrospective multicenter study(April 2012-November 2022)included untreated patients with suspected hepatocellular carcinoma undergoing gadoxetic acid-enhanced magnetic resonance imaging.Lesions from center 1 were partitioned into a development set(275 lesions used for five-fold cross-validation)and an internal testing set(62 lesions).Lesions from centers 2(85 lesions)and 3(104 lesions)constituted two external testing sets.Evi-LIRADS was designed by emulating the decision-making process of radiologists through a series of image processing algorithms,to recognize nonrim arterial phase hyper-enhancement,nonperipheral washout,and enhancing capsule,which provided detailed assessments of feature locations and patterns,improving the transparency of feature classification.Based on the three major image features and the automatically segmented lesion size,LIRADS categories were assigned using LI-RADS v2018 algorithm.Feature classification was evaluated using area under the receiver operating characteristic curve.LI-RADS categorization was assessed by accuracy.RESULTS The internal dataset included 337 patients from center 1,while external datasets comprised 76 patients from center 2 and 97 patients from center 3.For feature classification,areas under the receiver operating characteristic curves were 0.975,0.898,and 0.940 for arterial phase hyper-enhancement;0.803,0.824,and 0.850 for washout;0.759,0.800,and 0.784 for capsule across three datasets.Three-class LI-RADS categorization among LR-3,LR-4 and LR-5 achieved accuracies of 80.6%,74.1%,and 77.9%,respectively,surpassing comparison methods(58.6%-69.6%).LIRADS categorization between LR-3 and combined LR-4/LR-5 achieved 95.2%,88.2%,and 90.4%accuracies for the three datasets,respectively.The visualization provided detailed feature locations and patterns.Evi-LIRADS saved an average of 21.1 seconds per patient(58.8%of the time)compared with radiologists,excluding radiologists’quality control time.CONCLUSION Following LI-RADS guidelines and radiologists’decision-making process,Evi-LIRADS was developed through quantitative feature characterization,demonstrating good accuracy,robust generalization,improved efficiency,enhanced clinical relevance,and improved transparency.展开更多
Allergic rhinitis(AR)is a prevalent chronic inflammatory disorder that significantly impairs quality of life worldwide.In 2024,the World Federation of Chinese Medicine Societies(WFCMS)released the International Clinic...Allergic rhinitis(AR)is a prevalent chronic inflammatory disorder that significantly impairs quality of life worldwide.In 2024,the World Federation of Chinese Medicine Societies(WFCMS)released the International Clinical Practice Guidelines of Chinese Medicine:Allergic Rhinitis(SCM 80-2024),the first globally standardized evidence-based clinical practice guidelines for comprehensive TCM management of AR.Developed through a transparent,prospectively registered process on the PREPARE platform(Registration No.2023CN081),the guidelines synthesized data from 351 randomized controlled trials involving 43,276 patients and applied the GRADE-TCM framework,which integrates four categories of TCM-specific evidence.32 rec-ommendations were established through five rounds of Delphi consensus,covering four major TCM syndromes and both internal and external therapeutic interventions.This article presents the English interpretation of the guidelines.Beyond summarizing the core recommen-dations,it focuses on the methodological innovations underpinning the guidelines,the epistemological dis-tinctions between Chinese and Western medical paradigms,and the regulatory and practical challenges associated with its implementation in predominantly Western healthcare contexts.展开更多
Purpose:This research sets out to explore the practical application value of an innovative teaching mode that organically combines evidence-based medicine(EBM)with artificial intelligence(AI),and analyze its applicati...Purpose:This research sets out to explore the practical application value of an innovative teaching mode that organically combines evidence-based medicine(EBM)with artificial intelligence(AI),and analyze its application effect on undergraduate medical students during their ophthalmology internship.Methods:This research team independently built a multi-functional online teaching platform integrating EBM and AI technologies,which incorporates specialized evidence resource libraries,AI auxiliary diagnosis tools,and simulated clinical case modules.A total of 30 fifth-year clinical undergraduates receiving ophthalmology internship training were enrolled as research subjects and randomly assigned into two groups with 15 participants each.The experimental group adopted the newly developed EBM-AI integrated teaching method,while the control group received the conventional offline teaching mode.Multiple indicators were adopted to evaluate the teaching effect,covering students’professional theoretical reserves,EBM and AI-related comprehensive abilities,clinical decision-making level,autonomous learning enthusiasm,and subjective evaluation of teaching quality.Results:Before the intervention,there was no statistical difference in the basic ophthalmology knowledge reserve between the two groups(P>0.05).After the implementation of different teaching schemes,the experimental group outperformed the control group in all evaluation indicators.To be specific,the experimental group obtained higher scores in overall theoretical assessment(86.12±4.05 vs.74.93±5.62,P<0.001)and EBM/AI specialized knowledge test(36.25±2.31 vs.26.80±3.17,P<0.001).Meanwhile,the group also achieved better results in the Script Concordance Test(SCT)for clinical decision-making ability(81.60±5.24 vs.63.87±6.08,P<0.001).In terms of learning initiative,the weekly self-study duration of students in the experimental group was obviously longer than that of the control group(4.02±0.71 vs.1.68±0.44,P<0.001).Additionally,the student satisfaction rate of the new teaching model reached 93.3%,which was notably higher than 73.3%of the traditional teaching group(P=0.031).Conclusion:The integrated teaching model combining EBM and AI can effectively help interns consolidate EBM and AI professional knowledge,optimize clinical case analysis and decision-making capabilities,and stimulate their enthusiasm for independent learning.Importantly,the new teaching method will not affect students’mastery of basic ophthalmology knowledge.This optimized teaching scheme can serve as a reliable reference for promoting the innovative reform of modern ophthalmology higher education.展开更多
BACKGROUND Intensive care unit(ICU)-hospitalized patients have a high risk of developing delirium;however,the related diagnosis and treatment remain inadequate.AIM To clarify the preventive effect of evidence-based,no...BACKGROUND Intensive care unit(ICU)-hospitalized patients have a high risk of developing delirium;however,the related diagnosis and treatment remain inadequate.AIM To clarify the preventive effect of evidence-based,non-pharmacological care bundles on delirium in ICU-hospitalized patients.METHODS A total of 149 ICU patients(May 2022-May 2025)were enrolled,including 72 patients in the control group receiving routine nursing and 77 patients in the research group receiving evidence-based,non-pharmacological care bundles.Comparative analyses were conducted regarding delirium occurrence(incidence,time of first occurrence,and duration),nursing complications(deep venous thrombosis,ventilator-associated pneumonia,and unplanned extubation),clinical indices(mechanical ventilation duration,ICU length of stay,hospitalization time,and sedative duration),cognitive function(Chinese version of the Johns Hopkins Adapted Cognitive Exam),sleep quality(Richards-Campbell Sleep Questionnaire),sedation level(Richmond Agitation and Sedation Scale),health status(Acute Physiology and Chronic Health Evaluation II),anxiety and depression(Hamilton Anxiety Scale/Hamilton Depression Scale),and nursing satisfaction.RESULTS Compared with the controls,the research group showed lower delirium inci dence,fewer overall nursing complications,and shorter time of first delirium occurrence,delirium duration,mechanical ventilation duration,ICU stay,and hospitalization time.The research group also demonstrated reduced sedative and analgesic dosages;lower Richmond Agitation and Sedation Scale,Acute Physiology and Chronic Health Evaluation II,Hamilton Anxiety Scale,and Hamilton Depression Scale scores;and higher postinterventional Adapted Cognitive Exam and Richards-Campbell Sleep Questionnaire scores,as well as higher overall nursing satisfaction.CONCLUSION Evidence-based,non-pharmacological care bundles are highly effective in preventing delirium in ICU-hospitalized patients.展开更多
BACKGROUND Brain tumor resection under general anesthesia is the core treatment for intracranial tumors in children,but postoperative pain,anxiety,and poor compliance with rehabilitation care have become key factors a...BACKGROUND Brain tumor resection under general anesthesia is the core treatment for intracranial tumors in children,but postoperative pain,anxiety,and poor compliance with rehabilitation care have become key factors affecting the prognosis of children.Because children’s cognitive development is immature,they have a stronger fear response to surgical trauma,which may cause long-term psychological trauma.As a mature behavioral change theoretical framework,the informationmotivation-behavior(IMB)skills model is still blank in neurosurgery research.Based on this model,this study integrates evidence-based nursing and cognitive behavioral intervention to explore its impact on children after brain tumor resection under general anesthesia.AIM To study the application of evidence-based nursing and cognitive behavioral intervention based on the IMB model in the children.METHODS Ninety children undergoing brain tumor resection under general anesthesia at the hospital between January 2024 and January 2025 were randomly divided into a control group and an observation group,45 cases in each group.The control group received routine perioperative care.The observation group,on the other hand,received an integrated program based on the IMB model,supported by evidencebased nursing.SPSS22.0 software was used for data analysis,and P<0.05 was regarded as a statistically significant difference.RESULTS Following attrition,40 controls and 42 intervention subjects finished follow-up.Eight weeks later,the intervention cohort showed markedly superior Functional Independence Measure for Children and Gesell Developmental Scales results(P<0.05)and outperformed controls on all PedsQL™dimensions:Physical,emotional,social,and role functioning(P<0.05).Parents’overall disease knowledge mastery rate was 97.62%in the observation group,higher than 80.00%in the control group(P<0.05).Parent satisfaction was 97.62%in the observation group,higher than 77.50%in the control group(P<0.05).CONCLUSION The IMB model-based integrated care effectively promotes neurological recovery,improves quality of life,and enhances parental knowledge and satisfaction in children after brain tumor surgery.展开更多
Colorectal cancer is a high-incidence malignant tumor of the digestive tract worldwide.Colonoscopic screening and complete resection of early lesions serve as the core strategies to reduce its morbidity and mortality....Colorectal cancer is a high-incidence malignant tumor of the digestive tract worldwide.Colonoscopic screening and complete resection of early lesions serve as the core strategies to reduce its morbidity and mortality.Conventional white-light endoscopy(WLE)exhibits a high missed diagnosis rate for minute adenomas,flat lesions,laterally spreading tumors(LSTs),and inflammatory bowel disease(IBD)-associated dysplasia,which fails to meet the demands of precise early diagnosis.Chromoendoscopy(CE)enhances the fine mucosal microstructure,crypt morphology,and lesion boundaries via topical mucosal spraying of staining agents,thereby significantly improving lesion detection efficacy.Based on evidence-based medical data,this study systematically summarizes the mechanism of action,characteristics of commonly used staining agents,standardized operating procedures,and quality control key points of CE.By integrating randomized controlled trials(RCTs),meta-analyses,and domestic and international authoritative guidelines,this paper hierarchically evaluates its clinical value in adenoma detection,early colorectal cancer diagnosis,LST assessment,IBD-related dysplasia screening,and postoperative follow-up.It further conducts an evidence-based comparison of the diagnostic efficacy among CE,WLE,virtual chromoendoscopy,magnifying endoscopy,and artificial intelligence(AI)-assisted endoscopy.Additionally,the current limitations of existing studies are objectively summarized,and future research directions of this technology are prospected,aiming to provide evidence-based references for the standardized implementation of enhanced colonoscopy and the construction of a stratified early screening strategy for colorectal cancer.展开更多
Objective:To evaluate the efficacy of a perioperative pain management protocol based on evidence-based nursing principles in patients undergoing thoracoscopic surgery for lung cancer.Methods:A total of 112 patients un...Objective:To evaluate the efficacy of a perioperative pain management protocol based on evidence-based nursing principles in patients undergoing thoracoscopic surgery for lung cancer.Methods:A total of 112 patients undergoing thoracoscopic lung cancer surgery in the Department of Thoracic Surgery at a specific hospital between August 2025 and March 2026 were selected and randomly assigned to either a control group or an observation group,with 56 patients in each group.The control group received standard pain management,while the observation group received a pain management protocol based on evidence-based nursing.Results:At various postoperative time points,the observation group demonstrated significantly lower pain scores,both at rest and during activity,compared to the control group.Furthermore,within the first 48 hours post-surgery,the observation group consumed fewer opioids,mobilized out of bed earlier,experienced shorter postoperative hospital stays,and had a lower overall incidence of complications than the control group;all these differences were statistically significant(p<0.05).Conclusion:A perioperative pain management protocol established upon evidence-based nursing principles can effectively alleviate postoperative pain in patients undergoing thoracoscopic lung cancer surgery,reduce opioid consumption,facilitate postoperative recovery,lower the incidence of complications,and enhance patient satisfaction with nursing care.展开更多
Objective: This study aimed to investigate the effectiveness of integrating the concept of "evidence-based medicine" into the curriculum design and practice of residency training. Methods: A total of 35 medi...Objective: This study aimed to investigate the effectiveness of integrating the concept of "evidence-based medicine" into the curriculum design and practice of residency training. Methods: A total of 35 medical residents were randomly assigned to either a control group (n=17) or an observation group (n=18). The control group received traditional teaching methods, while the observation group incorporated evidence-based medicine principles into their training. Teaching outcomes were evaluated based on examination scores, teaching satisfaction, post rotation questionnaire responses, and comprehensive competency scores. Results: The observation group demonstrated significantly higher scores in basic theory, clinical case analysis, and clinical skill assessments compared to the control group (P<0.05). In the teaching satisfaction survey, the observation group achieved a 100% satisfaction rate, significantly higher than that of the control group (P=0.0397). Post rotation questionnaire results showed that the observation group exhibited markedly better improvements in clinical thinking, personal communication skills, self-learning ability, learning interest, and teamwork spirit compared to the control group (P<0.05). Comprehensive competency scores also revealed significantly superior performance in all categories for the observation group (P<0.05). Conclusion: Integrating evidence-based medicine principles into residency training curriculum design and practice significantly enhances teaching quality and outcomes, strengthens students' clinical thinking and comprehensive competencies, and warrants widespread adoption in medical education.展开更多
With the intensification of population aging,knee and hip joint replacement surgeries have become core methods for treating end-stage joint diseases,with over a million cases performed globally each year.Postoperative...With the intensification of population aging,knee and hip joint replacement surgeries have become core methods for treating end-stage joint diseases,with over a million cases performed globally each year.Postoperative rehabilitation nursing,as a crucial aspect of enhancing surgical outcomes,reducing complications,and facilitating patients’return to normal life,has its scientific and effective protocols directly influencing patient prognosis.This article systematically reviews the core research findings on rehabilitation nursing after joint replacement surgery based on the concept of evidence-based medicine,aiming to provide references for the formulation of standardized and personalized rehabilitation nursing plans in clinical settings.展开更多
Lower limb fractures are common orthopedic injuries in clinical practice.Due to factors such as prolonged bed rest,immobilization,and vascular injury,patients are at a higher risk of developing deep vein thrombosis(DV...Lower limb fractures are common orthopedic injuries in clinical practice.Due to factors such as prolonged bed rest,immobilization,and vascular injury,patients are at a higher risk of developing deep vein thrombosis(DVT),which can lead to pulmonary embolism in severe cases,endangering their lives and affecting their prognosis and quality of life.Evidence-based nursing,guided by clinical problems,integrates high-quality clinical evidence,nursing expertise,and individual patient needs to develop scientific and standardized nursing plans,offering greater effectiveness compared to traditional empirical nursing.Evidence-based multidimensional nursing interventions break through the limitations of single nursing approaches by constructing a comprehensive prevention system from multiple dimensions,including physiology,medication,rehabilitation,psychology,and health education,precisely targeting the risk factors for DVT formation.This article reviews the implementation content of multidimensional nursing interventions for patients with lower limb fractures and analyzes their application effectiveness in DVT prevention,providing a reference for optimizing clinical DVT prevention nursing plans,improving nursing quality,and enhancing patient prognosis for those with lower limb fractures.展开更多
Objective: To improve the clinical rehabilitation outcomes of patients after radial artery coronary intervention, this study aimed to analyze the application value of evidence-based nursing combined with planned decom...Objective: To improve the clinical rehabilitation outcomes of patients after radial artery coronary intervention, this study aimed to analyze the application value of evidence-based nursing combined with planned decompression intervention in reducing postoperative complication rates, enhancing comfort, and improving sleep quality. Methods: A total of 671 patients who underwent radial artery coronary intervention at the Department of Cardiology of a tertiary hospital in Yili, Xinjiang, from April 2023 to December 2023 were randomly selected using a sampling method. They were divided into a control group (n=219), Experimental Group 1 (n=223), and Experimental Group 2 (n=229) based on admission time. The control group received conventional clinical care, while the experimental groups received evidence-based nursing combined with planned decompression intervention in addition to routine care. Postoperative complications in the affected limbs were compared among the three groups, and postoperative comfort and sleep quality were assessed using the Kolcaba Comfort Questionnaire (GCQ) and the SPIEGEL scale, respectively. Results: The incidence of postoperative complications such as bleeding, swelling, and cyanosis in the experimental group was significantly lower than that in the control group (P<0.001). After intervention, the sleep quality score in the experimental group was markedly lower than that in the control group (P<0.001). Patient comfort scores showed a progressive improvement, rising from 77.64±5.96 in the control group to 86.41±5.04 in Experimental Group 2 (P<0.001). Conclusion: After coronary artery intervention and treatment via the radial artery, the application of evidence-based nursing combined with stress reduction intervention can reduce the risk of postoperative complications, improve postoperative comfort and sleep quality, and provide practical evidence for the optimization of clinical postoperative care plans.展开更多
Objective:To explore the application effect of evidence-based nursing in the postoperative care of patients with ureteral calculi undergoing holmium laser lithotripsy,analyze its impact on the incidence of postoperati...Objective:To explore the application effect of evidence-based nursing in the postoperative care of patients with ureteral calculi undergoing holmium laser lithotripsy,analyze its impact on the incidence of postoperative complications,the degree of stress response,and nursing satisfaction,and provide evidence-based support for optimizing clinical nursing practices.Methods:A total of 100 patients with ureteral calculi who underwent holmium laser lithotripsy in our hospital from January 2023 to June 2025 were selected and divided into an observation group(50 cases)and a control group(50 cases)using a random number table method.The control group received routine nursing interventions,while the observation group adopted an evidence-based nursing model.The incidence of postoperative complications(hematuria,urinary tract infection,renal colic,ureteral stricture),stress response indicators(heart rate,systolic blood pressure,diastolic blood pressure,Self-Rating Anxiety Scale(SAS)score,Self-Rating Depression Scale(SDS)score)before surgery and 24 hours after surgery,and nursing satisfaction were compared between the two groups.Results:The total incidence of postoperative complications in the observation group was significantly lower than that in the control group(p<0.05).At 24 hours after surgery,the heart rate,systolic blood pressure,diastolic blood pressure,SAS score,and SDS score in the observation group were significantly lower than those in the control group(all p<0.01).Nursing satisfaction in the observation group was significantly higher than that in the control group(p<0.01).Conclusion:Evidence-based nursing can effectively reduce the incidence of postoperative complications in patients with ureteral calculi undergoing holmium laser lithotripsy,alleviate patients’stress responses,and improve nursing satisfaction,demonstrating significant clinical application value.展开更多
基金supported by the Traditional Chinese Medicine Innovation Team and Talent Support Program-National Traditional Chinese Medicine Multidisciplinary Cross-Innovation Team Project。
摘要Objectives This study aimed to develop a competency-oriented ecological education model and evaluate the feasibility and preliminary outcomes of its implementation for enhancing evidence-based practice competencies among undergraduate nursing students.Methods An ecological education model was developed based on educational ecology theory and the input–environment–output(IEO)theoretical framework,and implemented from 2019 to 2024.The model integrated three core components:a four-year progressive competency development pathway(ranging from evidence-based thinking in year one to comprehensive practice application in year four);a three-tier ecological environment(comprising physical,classroom,and practice environments that incorporates six best practice spotlight organization guidelines into eight core courses);and multidimensional practice platforms,including health science communication and guideline translation.The reform was conducted at a nursing school of a double first-class university in Beijing,China.A naturalistic longitudinal cohort design was employed,which included 1,223 undergraduate nursing students at baseline(2019,pre-reform)and 1,237 at post-implementation(2024).A convergent parallel mixed-methods approach was used to evaluate the implementation outcomes.Quantitative data on academic performance and innovation outcomes were collected at both time points,baseline and post-implementation.Semi-structured interviews with 18 students were conducted to supplement the exploration of their learning experiences.Results Academic engagement increased from 78.5%to 97.3%,evidence-based graduation theses rose from 18.6%to 30.0%,and innovation and entrepreneurship projects increased from 40 to 150.Qualitative analysis revealed four themes and twelve subthemes,revealing enhanced critical appraisal skills(88.9%),evidence synthesis capabilities(94.4%),and professional confidence(83.3%)among students.Integrated mixed-methods analysis revealed stage-specific characteristics across academic years:a complementarity pattern in Year 1(foundational awareness building),a convergence pattern in Years 2–3(systematic competency construction),an expansion pattern during the Year 3 transition(role adaptation challenges),and a convergence pattern in Year 4(comprehensive transformation and professional confidence enhancement).Conclusions This feasibility study demonstrated that the ecological education model could be successfully implemented in undergraduate nursing education with promising preliminary outcomes.This study provides an initial framework for nursing education innovation and establishes foundational evidence warranting future rigorous controlled studies to examine the model’s effectiveness.
摘要Reflexology has recently gained attention as a complementary therapy, but existing evidence on its effectiveness for blood pressure (BP) remains scattered and inconsistent. This study aimed to synthesize and critically evaluate published systematic reviews and meta-analyses examining the impact of reflexology on BP. A comprehensive search was conducted in PubMed, Scopus, Web of Science, and Epistemonikos up to unti August 25, 2025. Eligible studies included systematic reviews and meta-analyses assessing the effects of reflexology on adult systolic BP and diastolic BP. Methodological quality was evaluated using the A MeaSurement Tool to Assess Systematic Reviews 2 tool, and overlap among primary studies was measured using the Corrected Covered Area (CCA) index. The review process followed the Preferred Reporting Items for Overviews of Reviews checklist. Nine reviews (five meta-analyses and four systematic reviews), including 43 primary studies, were identified.Meta-analytic results showed considerable heterogeneity, with findings ranging from no significant effect to mild or moderate BP reduction after reflexology. All included reviews were rated as critically low quality, mainly due to inadequate assessment of publication bias and insufficient evaluation of risk of bias in primary studies. Primary study overlap was low (CCA = 3.77%). The current evidence on the efficacy of reflexology for BP control remains uncertain and low in certainty. While reflexology appears safe and may contribute to small BP reductions, the evidence is insufficient to support strong clinical recommendations. Robust, large-scale randomized controlled trials and methodologically sound systematic reviews are needed to clarify the role of reflexology in hypertension management.
基金Supported by Suzhou Hepatobiliary Surgery Clinical Medical Center Construction Fund Project,No.szlcyxzxj202107。
摘要BACKGROUND With an aging society,older patients undergoing cholecystectomy often have multiple chronic diseases and require long-term multi-medication.Medication complexity significantly increases the risk of medication errors and adverse reactions,and effective nursing interventions are urgently required to ensure medication safety.AIM To investigate the efficacy of evidence-based nursing practices in mitigating polypharmacy risks among Suzhou Municipal Hospital Road Front Yard Area,thereby providing clinical guidance.METHODS The sixty older patients who underwent cholecystectomy between September 2024 and September 2025 treated with polypharmacy were enrolled.Using random number tables,hey were divided into study and control groups(n=30 each),who received routine medication nursing and evidence-based nursing,respectively.Pre-intervention and post-intervention comparisons were made between groups for medication knowledge,competence,and adherence scores.The incidences of duplicate medications,missed doses,self-discontinuation,unauthorized alterations,schedule changes,and adverse reaction rates assessed potential medication risks.RESULTS Both the study and control groups showed significant increases in medication knowledge,management competence,and adherence scores after intervention(all P<0.05).The study group had higher post-intervention scores(medication knowledge:87.29±5.09 vs 70.62±5.38;medication management competence:63.22±3.11 vs 56.19±4.08;medication adherence:7.13±1.04 vs 6.05±1.03,all P<0.05).The incidence of duplicate medication,missed doses,self-discontinuation,unauthorized dose alterations,and schedule modifications decreased in both groups post-intervention(all P<0.05),with lower rates in the study group(duplicate medication:13.33%vs 30.0%;missed doses:10.0%vs 26.67%;all P<0.05).The study group had a lower adverse reaction rate(3.33%vs 26.67%,P<0.05)and more patients with potential medication hazard level 0(83.33%vs 53.33%),while fewer patients had level 2 and 3 hazards(3.33%vs 16.67%and 0%vs 10.00%,respectively;all P<0.05).CONCLUSION Evidence-based nursing for polypharmacy risks in older adults undergoing cholecystectomy can enhance medication awareness,improve management and adherence,reduce adverse behaviors,and lower adverse reactions and hazard levels.
基金Gansu Provincial Health Industry Science and Technology Program(grant number:GSWSQN 2024-12)。
摘要Objective This study aimed to explore the facilitators of and barriers to the clinical translation of evidence-based nursing guidelines.Methods A convergent mixed-methods study design.First,206 nurses from 12 hospitals were selected as study participants,and the Chinese version of the Organizational Readiness to Change Assessment(ORCA)scale was administered to assess the current readiness for guideline implementation.Subsequently,for the qualitative study,purposive sampling was used to select 15 nurses from the quantitative study sample for semistructured interviews.The framework analysis method was applied to code the transcribed texts using the Consolidated Framework for Implementation Research(CFIR),and thematic analysis was employed to identify facilitators and barriers to guideline implementation.Finally,all facilitating and barrier factors were systematically synthesized,and implementation strategies were matched using the Consolidated Framework for Implementation Research–Expert Recommendations for Implementing Change(CFIR–ERIC)tool.Results The organizational change readiness score was moderate-to-high(248.77±33.35).The quantitative study identified 25 facilitating factors(such as the scientific rigor of guideline implementation and a positive departmental culture)and 16 barriers(including insufficient resources to address patient awareness or needs and inadequate communication among team members).The qualitative study identified 25 facilitating factors(such as high self-efficacy in evidence-based practice and leadership support)and 11 barriers(such as implementation complexity and resource constraints).From a mixed-methods analysis,the top three barriers were identified as a lack of incentives,insufficient resources,and interdepartmental communication barriers.Based on the CFIR-ERIC mapping,implementation recommendations targeting the main barriers were identified,including tailoring implementation strategies,modifying incentive mechanisms or compensation structures,and establishing communication networks among team members.Conclusion This study systematically revealed,through a mixed-methods approach,the current status of nurses’readiness to participate in guideline implementation in China,as well as the facilitating factors and barriers.In the future,targeted strategies should be developed based on the identified barriers to promote the sustained implementation of guidelines.
摘要Objectives We aimed to describe the implementation process and provide a baseline characterization of suicidal behavior during the first year of implementing the Registered Nurses’Association of Ontario(RNAO)Best Practice Guideline(BPG)for suicide prevention in a tertiary occupational hospital in Santiago,Chile.Methods A cross-sectional descriptive study was guided by the Knowledge-to-Action(KTA)framework.The implementation process included:1)assessment of the local context;2)adaptation of 26 RNAO BPG recommendations through the first four phases of the KTA cycle;and 3)use of institutional data from April 2024 to April 2025 to establish a baseline of suicidal behavior.Data sources included Emergency Department(ED)consultations,hospital admissions,liaison psychiatry referrals,patient safety reports,and staff training records.Data were analyzed using descriptive statistics.Results The preliminary assessment identified variable levels of compliance with the RNAO BPG recommendations,with 9 fully met,12 partially met,and 4 unmet.Contextual analysis revealed key barriers and facilitators at the individual,team,and organizational levels,and identified priority stakeholders.Based on these findings,context-adapted strategies were developed,including protocol standardization,staff training,structured referral pathways,and environmental safety measures.Institutional data showed 7,936 ED consultations,of which 577(7.3%)involved suicidal behavior.Among 368 admitted patients with primary mental health diagnoses,336(91.3%)were linked to suicide risk.Liaison psychiatry documented 7 cases from medical-surgical wards,while patient safety records identified three suicide-related sentinel events associated with mild to moderate harm.Conclusions Implementation demonstrated that evidence-based nursing,guided by the KTA framework,supports standardized detection and management of suicide risk.These findings provide an initial characterization of suicidal behavior in an occupational health setting and underscore the importance of context-adapted strategies,continuous training,and institutional cultural change to support implementation.
摘要Objective:To describe the implementation of evidence-based practice(EBP)and identify the associated factors among clinical nurses working at an oncology hospital in Central Vietnam.Methods:A cross-sectional study was conducted with 190 clinical nurses recruited from an oncology hospital in Central Vietnam.The self-administered Evidence-Based Practice Questionnaire(EBPQ)was employed to assess the nurses'knowledge/skills,attitudes,and implementation of EBP.Data analysis utilized descriptive statistics,the Mann-Whitney test,the Kruskal-Wallis test,and Spearman's rho correlation.Results:The mean total score for EBP implementation among the nurses was 29.52(SD=7.14)out of 42 scores.The most frequently undertaken activity was sharing evidence with colleagues,whereas finding relevant evidence was the least performed.The level of EBP implementation significantly varied based on the nurses'role types and their participation in related courses(P<0.05).Moreover,a strong positive correlation was observed between EBP implementation and both knowledge/skills(r=0.703,P<0.001)and attitudes toward EBP(r=0.536,P<0.001).Conclusions:The implementation of EBP by oncology nurses is generally moderate and is significantly positively correlated with their knowledge/skills and attitudes toward EBP.These findings underscore the importance of enhancing educational programs and facilitating suppor tive institutional policies to fur ther encourage the adoption of EBP among nurses.
基金supported by a postdoctoral fellowship from the Social Sciences and Humanities Research Council of Canadastipends from his postdoctoral supervisor+1 种基金through her Tier I Canada Research Chairsupported by Cumming School of Medicine through the Achievers in Medical Sciences Postdoctoral Fellowship。
摘要Despite the established need for evidence-based practice(EBP),its implementation in nursing remainsinconsistent due to organizational,presentation,and individual barriers.Mentorship is frequently citedas a solution,yet its mechanisms for bridging evidence to practice are underexplored.This studyaimed to examine how mentorship functions as a strategy to support EBP implementation.First,wediscuss how mentorship addresses nurse-related barriers by providing just-in-time coaching and rolemodeling,enabling mentors to build mentees’critical appraisal skills and clinical Second,we examine how mentorship mitigates presentation-related barriers by enabling mentors to act asknowledge brokers,translating complex evidence into accessible,conteguidance for thebedside.Third,we outline how mentorship addresses organizational or setting-related barriers byembedding EBP into formalized structures,including mentor roles,protected time,and evaluation metrics.To operationalize these mechanisms,we propose an implementation mapping frameworkthat key actors,targeted actions,and measurable outcomes while addressing structuralchallenges such as limited protected time.We conclude that formalized mentorship is essential fortransforming theoretical evidence into sustainable bedside practice and fostering a culture of excellencethat directly improves patient outcomes.
摘要Objectives Evidence-based practice(EBP)is widely accepted as central to high-quality nursing care,yet integration into acute care settings remains uneven.Nurses play a vital role in applying evidence,but organizational hierarchies,time constraints,and limited interprofessional collaboration often restrict their ability to lead or sustain EBP.This study explored how nurses enact,adapt,and promote EBP through interprofessional collaboration,everyday clinical leadership,and access to continuing professional development.Methods An embedded comparative case study design was used,informed by interpretive and ethnographic principles.The research was conducted across two large hospitals in England with differing leadership and governance structures.Twenty-five participants were included,consisting of nurses,nurse managers,and physicians.Data were collected over six years through 25 semi-structured interviews,60 h of non-participant observation,and review of policy and quality improvement documents.Data were analyzed using reflexive thematic analysis.Results Five key themes were identified:leadership practices and organizational support;professional identity and EBP ownership;interprofessional collaboration and communication;structural barriers and resource constraints;and capacity building through learning and feedback.Nurses enacted EBP through informal leadership,peer mentorship,and grassroots innovation.Structural barriers such as limited time,unequal access to continuing professional development,and fragmented collaboration significantly affected implementation.Conclusions Nurses play an active and sustained role in leading EBP through their relationships,clinical judgment,and commitment to care quality.However,their efforts are shaped by the broader organizational systems in which they work.Supporting interprofessional collaboration,distributed leadership,establishing EBP mentoring roles,and ensuring equitable access to continuing professional development are essential for consistent and inclusive evidence use.Hospital managers and policymakers should prioritize structural investment in team-based learning,inclusive governance and digital access.
基金Supported by National Natural Science Foundation of China,No.82271956Shanghai Municipal Science and Technology Explorer Project,No.23TS1400500.
摘要BACKGROUND The Liver Imaging Reporting and Data System(LI-RADS)is widely used for the diagnosis of hepatocellular carcinoma,but feature scoring by radiologists is subjective and time-consuming.An urgent need exists for an objective and efficient radiologist-supervised automated LI-RADS categorization system.AIM To develop an evidence-based radiologist-supervised automated LI-RADS grade 3(LR-3),4(LR-4)and 5(LR-5)categorization system(Evi-LIRADS)through quantitative feature characterization,following LI-RADS v2018.METHODS This retrospective multicenter study(April 2012-November 2022)included untreated patients with suspected hepatocellular carcinoma undergoing gadoxetic acid-enhanced magnetic resonance imaging.Lesions from center 1 were partitioned into a development set(275 lesions used for five-fold cross-validation)and an internal testing set(62 lesions).Lesions from centers 2(85 lesions)and 3(104 lesions)constituted two external testing sets.Evi-LIRADS was designed by emulating the decision-making process of radiologists through a series of image processing algorithms,to recognize nonrim arterial phase hyper-enhancement,nonperipheral washout,and enhancing capsule,which provided detailed assessments of feature locations and patterns,improving the transparency of feature classification.Based on the three major image features and the automatically segmented lesion size,LIRADS categories were assigned using LI-RADS v2018 algorithm.Feature classification was evaluated using area under the receiver operating characteristic curve.LI-RADS categorization was assessed by accuracy.RESULTS The internal dataset included 337 patients from center 1,while external datasets comprised 76 patients from center 2 and 97 patients from center 3.For feature classification,areas under the receiver operating characteristic curves were 0.975,0.898,and 0.940 for arterial phase hyper-enhancement;0.803,0.824,and 0.850 for washout;0.759,0.800,and 0.784 for capsule across three datasets.Three-class LI-RADS categorization among LR-3,LR-4 and LR-5 achieved accuracies of 80.6%,74.1%,and 77.9%,respectively,surpassing comparison methods(58.6%-69.6%).LIRADS categorization between LR-3 and combined LR-4/LR-5 achieved 95.2%,88.2%,and 90.4%accuracies for the three datasets,respectively.The visualization provided detailed feature locations and patterns.Evi-LIRADS saved an average of 21.1 seconds per patient(58.8%of the time)compared with radiologists,excluding radiologists’quality control time.CONCLUSION Following LI-RADS guidelines and radiologists’decision-making process,Evi-LIRADS was developed through quantitative feature characterization,demonstrating good accuracy,robust generalization,improved efficiency,enhanced clinical relevance,and improved transparency.
基金World Federation of Chinese Medicine Societies(WFCMS)International Standard Develop-ment Project(SCM NP 2020-0097)National Natural Science Foun-dation of China(No.82474587)+1 种基金Sichuan Natural Science Foundation Project(23NSFSC0668)Xinglin Scholars Scientific Research Pro-motion Plan of Chengdu University of Traditional Chinese Medicine(No.XKTD2021003).
摘要Allergic rhinitis(AR)is a prevalent chronic inflammatory disorder that significantly impairs quality of life worldwide.In 2024,the World Federation of Chinese Medicine Societies(WFCMS)released the International Clinical Practice Guidelines of Chinese Medicine:Allergic Rhinitis(SCM 80-2024),the first globally standardized evidence-based clinical practice guidelines for comprehensive TCM management of AR.Developed through a transparent,prospectively registered process on the PREPARE platform(Registration No.2023CN081),the guidelines synthesized data from 351 randomized controlled trials involving 43,276 patients and applied the GRADE-TCM framework,which integrates four categories of TCM-specific evidence.32 rec-ommendations were established through five rounds of Delphi consensus,covering four major TCM syndromes and both internal and external therapeutic interventions.This article presents the English interpretation of the guidelines.Beyond summarizing the core recommen-dations,it focuses on the methodological innovations underpinning the guidelines,the epistemological dis-tinctions between Chinese and Western medical paradigms,and the regulatory and practical challenges associated with its implementation in predominantly Western healthcare contexts.
基金Sichuan Province 2025 High-Quality Educational and Teaching Resource Construction Project-High-Quality Textbook Cases for Professional Degree Graduate Programs(Rong Li)。
摘要Purpose:This research sets out to explore the practical application value of an innovative teaching mode that organically combines evidence-based medicine(EBM)with artificial intelligence(AI),and analyze its application effect on undergraduate medical students during their ophthalmology internship.Methods:This research team independently built a multi-functional online teaching platform integrating EBM and AI technologies,which incorporates specialized evidence resource libraries,AI auxiliary diagnosis tools,and simulated clinical case modules.A total of 30 fifth-year clinical undergraduates receiving ophthalmology internship training were enrolled as research subjects and randomly assigned into two groups with 15 participants each.The experimental group adopted the newly developed EBM-AI integrated teaching method,while the control group received the conventional offline teaching mode.Multiple indicators were adopted to evaluate the teaching effect,covering students’professional theoretical reserves,EBM and AI-related comprehensive abilities,clinical decision-making level,autonomous learning enthusiasm,and subjective evaluation of teaching quality.Results:Before the intervention,there was no statistical difference in the basic ophthalmology knowledge reserve between the two groups(P>0.05).After the implementation of different teaching schemes,the experimental group outperformed the control group in all evaluation indicators.To be specific,the experimental group obtained higher scores in overall theoretical assessment(86.12±4.05 vs.74.93±5.62,P<0.001)and EBM/AI specialized knowledge test(36.25±2.31 vs.26.80±3.17,P<0.001).Meanwhile,the group also achieved better results in the Script Concordance Test(SCT)for clinical decision-making ability(81.60±5.24 vs.63.87±6.08,P<0.001).In terms of learning initiative,the weekly self-study duration of students in the experimental group was obviously longer than that of the control group(4.02±0.71 vs.1.68±0.44,P<0.001).Additionally,the student satisfaction rate of the new teaching model reached 93.3%,which was notably higher than 73.3%of the traditional teaching group(P=0.031).Conclusion:The integrated teaching model combining EBM and AI can effectively help interns consolidate EBM and AI professional knowledge,optimize clinical case analysis and decision-making capabilities,and stimulate their enthusiasm for independent learning.Importantly,the new teaching method will not affect students’mastery of basic ophthalmology knowledge.This optimized teaching scheme can serve as a reliable reference for promoting the innovative reform of modern ophthalmology higher education.
基金Supported by Chongqing Municipal Science and Technology Health Joint Medical Research Project(General Program),No.2023MSXM052.
摘要BACKGROUND Intensive care unit(ICU)-hospitalized patients have a high risk of developing delirium;however,the related diagnosis and treatment remain inadequate.AIM To clarify the preventive effect of evidence-based,non-pharmacological care bundles on delirium in ICU-hospitalized patients.METHODS A total of 149 ICU patients(May 2022-May 2025)were enrolled,including 72 patients in the control group receiving routine nursing and 77 patients in the research group receiving evidence-based,non-pharmacological care bundles.Comparative analyses were conducted regarding delirium occurrence(incidence,time of first occurrence,and duration),nursing complications(deep venous thrombosis,ventilator-associated pneumonia,and unplanned extubation),clinical indices(mechanical ventilation duration,ICU length of stay,hospitalization time,and sedative duration),cognitive function(Chinese version of the Johns Hopkins Adapted Cognitive Exam),sleep quality(Richards-Campbell Sleep Questionnaire),sedation level(Richmond Agitation and Sedation Scale),health status(Acute Physiology and Chronic Health Evaluation II),anxiety and depression(Hamilton Anxiety Scale/Hamilton Depression Scale),and nursing satisfaction.RESULTS Compared with the controls,the research group showed lower delirium inci dence,fewer overall nursing complications,and shorter time of first delirium occurrence,delirium duration,mechanical ventilation duration,ICU stay,and hospitalization time.The research group also demonstrated reduced sedative and analgesic dosages;lower Richmond Agitation and Sedation Scale,Acute Physiology and Chronic Health Evaluation II,Hamilton Anxiety Scale,and Hamilton Depression Scale scores;and higher postinterventional Adapted Cognitive Exam and Richards-Campbell Sleep Questionnaire scores,as well as higher overall nursing satisfaction.CONCLUSION Evidence-based,non-pharmacological care bundles are highly effective in preventing delirium in ICU-hospitalized patients.
摘要BACKGROUND Brain tumor resection under general anesthesia is the core treatment for intracranial tumors in children,but postoperative pain,anxiety,and poor compliance with rehabilitation care have become key factors affecting the prognosis of children.Because children’s cognitive development is immature,they have a stronger fear response to surgical trauma,which may cause long-term psychological trauma.As a mature behavioral change theoretical framework,the informationmotivation-behavior(IMB)skills model is still blank in neurosurgery research.Based on this model,this study integrates evidence-based nursing and cognitive behavioral intervention to explore its impact on children after brain tumor resection under general anesthesia.AIM To study the application of evidence-based nursing and cognitive behavioral intervention based on the IMB model in the children.METHODS Ninety children undergoing brain tumor resection under general anesthesia at the hospital between January 2024 and January 2025 were randomly divided into a control group and an observation group,45 cases in each group.The control group received routine perioperative care.The observation group,on the other hand,received an integrated program based on the IMB model,supported by evidencebased nursing.SPSS22.0 software was used for data analysis,and P<0.05 was regarded as a statistically significant difference.RESULTS Following attrition,40 controls and 42 intervention subjects finished follow-up.Eight weeks later,the intervention cohort showed markedly superior Functional Independence Measure for Children and Gesell Developmental Scales results(P<0.05)and outperformed controls on all PedsQL™dimensions:Physical,emotional,social,and role functioning(P<0.05).Parents’overall disease knowledge mastery rate was 97.62%in the observation group,higher than 80.00%in the control group(P<0.05).Parent satisfaction was 97.62%in the observation group,higher than 77.50%in the control group(P<0.05).CONCLUSION The IMB model-based integrated care effectively promotes neurological recovery,improves quality of life,and enhances parental knowledge and satisfaction in children after brain tumor surgery.
基金Intramural Research Projects of Foshan Greater Bay Area General Hospital(Project No.:FX2025016)。
摘要Colorectal cancer is a high-incidence malignant tumor of the digestive tract worldwide.Colonoscopic screening and complete resection of early lesions serve as the core strategies to reduce its morbidity and mortality.Conventional white-light endoscopy(WLE)exhibits a high missed diagnosis rate for minute adenomas,flat lesions,laterally spreading tumors(LSTs),and inflammatory bowel disease(IBD)-associated dysplasia,which fails to meet the demands of precise early diagnosis.Chromoendoscopy(CE)enhances the fine mucosal microstructure,crypt morphology,and lesion boundaries via topical mucosal spraying of staining agents,thereby significantly improving lesion detection efficacy.Based on evidence-based medical data,this study systematically summarizes the mechanism of action,characteristics of commonly used staining agents,standardized operating procedures,and quality control key points of CE.By integrating randomized controlled trials(RCTs),meta-analyses,and domestic and international authoritative guidelines,this paper hierarchically evaluates its clinical value in adenoma detection,early colorectal cancer diagnosis,LST assessment,IBD-related dysplasia screening,and postoperative follow-up.It further conducts an evidence-based comparison of the diagnostic efficacy among CE,WLE,virtual chromoendoscopy,magnifying endoscopy,and artificial intelligence(AI)-assisted endoscopy.Additionally,the current limitations of existing studies are objectively summarized,and future research directions of this technology are prospected,aiming to provide evidence-based references for the standardized implementation of enhanced colonoscopy and the construction of a stratified early screening strategy for colorectal cancer.
摘要Objective:To evaluate the efficacy of a perioperative pain management protocol based on evidence-based nursing principles in patients undergoing thoracoscopic surgery for lung cancer.Methods:A total of 112 patients undergoing thoracoscopic lung cancer surgery in the Department of Thoracic Surgery at a specific hospital between August 2025 and March 2026 were selected and randomly assigned to either a control group or an observation group,with 56 patients in each group.The control group received standard pain management,while the observation group received a pain management protocol based on evidence-based nursing.Results:At various postoperative time points,the observation group demonstrated significantly lower pain scores,both at rest and during activity,compared to the control group.Furthermore,within the first 48 hours post-surgery,the observation group consumed fewer opioids,mobilized out of bed earlier,experienced shorter postoperative hospital stays,and had a lower overall incidence of complications than the control group;all these differences were statistically significant(p<0.05).Conclusion:A perioperative pain management protocol established upon evidence-based nursing principles can effectively alleviate postoperative pain in patients undergoing thoracoscopic lung cancer surgery,reduce opioid consumption,facilitate postoperative recovery,lower the incidence of complications,and enhance patient satisfaction with nursing care.
摘要Objective: This study aimed to investigate the effectiveness of integrating the concept of "evidence-based medicine" into the curriculum design and practice of residency training. Methods: A total of 35 medical residents were randomly assigned to either a control group (n=17) or an observation group (n=18). The control group received traditional teaching methods, while the observation group incorporated evidence-based medicine principles into their training. Teaching outcomes were evaluated based on examination scores, teaching satisfaction, post rotation questionnaire responses, and comprehensive competency scores. Results: The observation group demonstrated significantly higher scores in basic theory, clinical case analysis, and clinical skill assessments compared to the control group (P<0.05). In the teaching satisfaction survey, the observation group achieved a 100% satisfaction rate, significantly higher than that of the control group (P=0.0397). Post rotation questionnaire results showed that the observation group exhibited markedly better improvements in clinical thinking, personal communication skills, self-learning ability, learning interest, and teamwork spirit compared to the control group (P<0.05). Comprehensive competency scores also revealed significantly superior performance in all categories for the observation group (P<0.05). Conclusion: Integrating evidence-based medicine principles into residency training curriculum design and practice significantly enhances teaching quality and outcomes, strengthens students' clinical thinking and comprehensive competencies, and warrants widespread adoption in medical education.
摘要With the intensification of population aging,knee and hip joint replacement surgeries have become core methods for treating end-stage joint diseases,with over a million cases performed globally each year.Postoperative rehabilitation nursing,as a crucial aspect of enhancing surgical outcomes,reducing complications,and facilitating patients’return to normal life,has its scientific and effective protocols directly influencing patient prognosis.This article systematically reviews the core research findings on rehabilitation nursing after joint replacement surgery based on the concept of evidence-based medicine,aiming to provide references for the formulation of standardized and personalized rehabilitation nursing plans in clinical settings.
摘要Lower limb fractures are common orthopedic injuries in clinical practice.Due to factors such as prolonged bed rest,immobilization,and vascular injury,patients are at a higher risk of developing deep vein thrombosis(DVT),which can lead to pulmonary embolism in severe cases,endangering their lives and affecting their prognosis and quality of life.Evidence-based nursing,guided by clinical problems,integrates high-quality clinical evidence,nursing expertise,and individual patient needs to develop scientific and standardized nursing plans,offering greater effectiveness compared to traditional empirical nursing.Evidence-based multidimensional nursing interventions break through the limitations of single nursing approaches by constructing a comprehensive prevention system from multiple dimensions,including physiology,medication,rehabilitation,psychology,and health education,precisely targeting the risk factors for DVT formation.This article reviews the implementation content of multidimensional nursing interventions for patients with lower limb fractures and analyzes their application effectiveness in DVT prevention,providing a reference for optimizing clinical DVT prevention nursing plans,improving nursing quality,and enhancing patient prognosis for those with lower limb fractures.
摘要Objective: To improve the clinical rehabilitation outcomes of patients after radial artery coronary intervention, this study aimed to analyze the application value of evidence-based nursing combined with planned decompression intervention in reducing postoperative complication rates, enhancing comfort, and improving sleep quality. Methods: A total of 671 patients who underwent radial artery coronary intervention at the Department of Cardiology of a tertiary hospital in Yili, Xinjiang, from April 2023 to December 2023 were randomly selected using a sampling method. They were divided into a control group (n=219), Experimental Group 1 (n=223), and Experimental Group 2 (n=229) based on admission time. The control group received conventional clinical care, while the experimental groups received evidence-based nursing combined with planned decompression intervention in addition to routine care. Postoperative complications in the affected limbs were compared among the three groups, and postoperative comfort and sleep quality were assessed using the Kolcaba Comfort Questionnaire (GCQ) and the SPIEGEL scale, respectively. Results: The incidence of postoperative complications such as bleeding, swelling, and cyanosis in the experimental group was significantly lower than that in the control group (P<0.001). After intervention, the sleep quality score in the experimental group was markedly lower than that in the control group (P<0.001). Patient comfort scores showed a progressive improvement, rising from 77.64±5.96 in the control group to 86.41±5.04 in Experimental Group 2 (P<0.001). Conclusion: After coronary artery intervention and treatment via the radial artery, the application of evidence-based nursing combined with stress reduction intervention can reduce the risk of postoperative complications, improve postoperative comfort and sleep quality, and provide practical evidence for the optimization of clinical postoperative care plans.
摘要Objective:To explore the application effect of evidence-based nursing in the postoperative care of patients with ureteral calculi undergoing holmium laser lithotripsy,analyze its impact on the incidence of postoperative complications,the degree of stress response,and nursing satisfaction,and provide evidence-based support for optimizing clinical nursing practices.Methods:A total of 100 patients with ureteral calculi who underwent holmium laser lithotripsy in our hospital from January 2023 to June 2025 were selected and divided into an observation group(50 cases)and a control group(50 cases)using a random number table method.The control group received routine nursing interventions,while the observation group adopted an evidence-based nursing model.The incidence of postoperative complications(hematuria,urinary tract infection,renal colic,ureteral stricture),stress response indicators(heart rate,systolic blood pressure,diastolic blood pressure,Self-Rating Anxiety Scale(SAS)score,Self-Rating Depression Scale(SDS)score)before surgery and 24 hours after surgery,and nursing satisfaction were compared between the two groups.Results:The total incidence of postoperative complications in the observation group was significantly lower than that in the control group(p<0.05).At 24 hours after surgery,the heart rate,systolic blood pressure,diastolic blood pressure,SAS score,and SDS score in the observation group were significantly lower than those in the control group(all p<0.01).Nursing satisfaction in the observation group was significantly higher than that in the control group(p<0.01).Conclusion:Evidence-based nursing can effectively reduce the incidence of postoperative complications in patients with ureteral calculi undergoing holmium laser lithotripsy,alleviate patients’stress responses,and improve nursing satisfaction,demonstrating significant clinical application value.