In response to the challenges of inadequate predictive accuracy and limited generalization capability in data-driven modeling for the mechanical properties of the cold-rolled strip steel,a predictive modeling method n...In response to the challenges of inadequate predictive accuracy and limited generalization capability in data-driven modeling for the mechanical properties of the cold-rolled strip steel,a predictive modeling method named RFR-WOA is developed based on random forest regression(RFR)and whale optimization algorithm(WOA).Firstly,using Pearson and Spearman correlation analysis and Gini coefficient importance ranking on an actual production dataset containing 37,878 samples,22 key variables are selected as model inputs from 112 variables that affect mechanical properties.Subsequently,an RFR-based predictive model for the mechanical properties of cold-rolled strip steel is constructed.Then,with the combination of the coefficient of determination(R2)and root mean square error as the optimization objective,the hyperparameters of RFR model are iteratively optimized using WOA,and better predictive effectiveness is obtained.Finally,the mechanical properties prediction model based on RFR-WOA is compared with models established using deep neural networks,convolutional neural networks,and other methods.The test results on 9469 samples of actual production data show that the model developed present has better predictive accuracy and generalization capability.展开更多
A switch from avian-typeα-2,3 to human-typeα-2,6 receptors is an essential element for the initiation of a pandemic from an avian influenza virus.Some H9N2 viruses exhibit a preference for binding to human-typeα-2,...A switch from avian-typeα-2,3 to human-typeα-2,6 receptors is an essential element for the initiation of a pandemic from an avian influenza virus.Some H9N2 viruses exhibit a preference for binding to human-typeα-2,6 receptors.This identifies their potential threat to public health.However,our understanding of the molecular basis for the switch of receptor preference is still limited.In this study,we employed the random forest algorithm to identify the potentially key amino acid sites within hemagglutinin(HA),which are associated with the receptor binding ability of H9N2 avian influenza virus(AIV).Subsequently,these sites were further verified by receptor binding assays.A total of 12 substitutions in the HA protein(N158D,N158S,A160 N,A160D,A160T,T163I,T163V,V190T,V190A,D193 N,D193G,and N231D)were predicted to prefer binding toα-2,6 receptors.Except for the V190T substitution,the other substitutions were demonstrated to display an affinity for preferential binding toα-2,6 receptors by receptor binding assays.Especially,the A160T substitution caused a significant upregulation of immune-response genes and an increased mortality rate in mice.Our findings provide novel insights into understanding the genetic basis of receptor preference of the H9N2 AIV.展开更多
Stand age plays a crucial role in forest biomass estimation and carbon cycle modeling.Assessing the uncertainty of stand age prediction models and identifying the key driving factors in the modeling process have becom...Stand age plays a crucial role in forest biomass estimation and carbon cycle modeling.Assessing the uncertainty of stand age prediction models and identifying the key driving factors in the modeling process have become major challenges in forestry research.In this study,we selected the Shaanxi-Gansu-Ningxia region of Northeast China as the research area and utilized multi-source datasets from the summer of 2019 to extract information on spectral,textural,climatic,water balance,and stand characteristics.By integrating the Random Forest(RF)model with Monte Carlo(MC)simulation,we constructed six regression models based on different combina-tions of features and evaluated the uncertainty of each model.Furthermore,we investigated the driving factors influencing stand age modeling by analyzing the effects of different types of features on age inversion.Model performance and accuracy were assessed using the root mean square error(RMSE),mean absolute error(MAE),and the coefficient of determination(R2),while the relative root mean square error(rRMSE)was employed to quantify model uncertainty.The results indicate that the scenarios with more obvious improve-ment in accuracy and effective reduction in uncertainty were Scenario 3 with the inclusion of climate and water balance information(RMSE=25.54 yr,MAE=18.03 yr,R2=0.51,rRMSE=19.17%)and Scenario 5 with the inclusion of stand characterization informa-tion(RMSE=18.47 yr,MAE=13.05 yr,R2=0.74,rRMSE=16.99%).Scenario 6,incorporating all feature types,achieved the highest accuracy(RMSE=17.60 yr,MAE=12.06 yr,R2=0.77,rRMSE=14.19%).In this study,elevation,minimum temperature,and diameter at breast height(DBH)emerged as the key drivers of stand-age modeling.The proposed method can be used to identify drivers and to quantify uncertainty in stand-age estimation,providing a useful reference for improving model accuracy and uncertainty assessment.展开更多
During shield tunneling,ground deformation poses significant safety risks.The full optimization strategy ignores interactions between parameters,resulting in suboptimal performance in the pre-control of settlement in ...During shield tunneling,ground deformation poses significant safety risks.The full optimization strategy ignores interactions between parameters,resulting in suboptimal performance in the pre-control of settlement in earth pressure balance shields.To address this problem,this paper proposes an integrated strategy that combines optimization and inversion,minimizing parameter interaction interference through adaptive adjustment of shield operation parameters.This mechanism performs an optimization search on the key operation parameters for settlement control,while the remaining operation parameters are predicted through inversion.Taking the Changchun Metro Line 6 project as an example,a bidirectional long short-term memory(Bi-LSTM)model enhanced by a multi-head self-attention(MHSA)mechanism is used to predict shield tunneling-induced settlement with spatiotemporal sequence dependency relationships.Particle swarm optimization and a random forest algorithm are used for optimization and inversion operations in the integrated mechanism,respectively.Subsequent ring position tests showed that the integrated mechanism-based adaptive adjustment strategy limited the average fluctuation of uncontrollable parameters to±13.95%compared to±34.27%for the full optimization strategy.The actual average settlement was only 3.81 mm compared to 4.72 mm for the full optimization strategy through collaborative parameter adjustment.The application validated the feasibility and applicability of the integrated mechanism,providing important references for the adaptive adjustment of shield parameters and tunnel construction automation.展开更多
基金supported by National Natural Science Foundation of China(Grant 62573375)the Natural Science Foundation of Hebei Province(Grant F2024203038)+2 种基金the Science and Technology Research and Development Plan Project of Qinhuangdao City(Grant 202302B048)the Provincial Key Laboratory Performance Subsidy Project(Grant 22567612H)the Shandong Provincial Natural Science Foundation Youth Project(ZR2023QF044)。
摘要In response to the challenges of inadequate predictive accuracy and limited generalization capability in data-driven modeling for the mechanical properties of the cold-rolled strip steel,a predictive modeling method named RFR-WOA is developed based on random forest regression(RFR)and whale optimization algorithm(WOA).Firstly,using Pearson and Spearman correlation analysis and Gini coefficient importance ranking on an actual production dataset containing 37,878 samples,22 key variables are selected as model inputs from 112 variables that affect mechanical properties.Subsequently,an RFR-based predictive model for the mechanical properties of cold-rolled strip steel is constructed.Then,with the combination of the coefficient of determination(R2)and root mean square error as the optimization objective,the hyperparameters of RFR model are iteratively optimized using WOA,and better predictive effectiveness is obtained.Finally,the mechanical properties prediction model based on RFR-WOA is compared with models established using deep neural networks,convolutional neural networks,and other methods.The test results on 9469 samples of actual production data show that the model developed present has better predictive accuracy and generalization capability.
基金supported by the National Natural Science Foundation of China(32273037 and 32102636)the Guangdong Major Project of Basic and Applied Basic Research(2020B0301030007)+4 种基金Laboratory of Lingnan Modern Agriculture Project(NT2021007)the Guangdong Science and Technology Innovation Leading Talent Program(2019TX05N098)the 111 Center(D20008)the double first-class discipline promotion project(2023B10564003)the Department of Education of Guangdong Province(2019KZDXM004 and 2019KCXTD001).
摘要A switch from avian-typeα-2,3 to human-typeα-2,6 receptors is an essential element for the initiation of a pandemic from an avian influenza virus.Some H9N2 viruses exhibit a preference for binding to human-typeα-2,6 receptors.This identifies their potential threat to public health.However,our understanding of the molecular basis for the switch of receptor preference is still limited.In this study,we employed the random forest algorithm to identify the potentially key amino acid sites within hemagglutinin(HA),which are associated with the receptor binding ability of H9N2 avian influenza virus(AIV).Subsequently,these sites were further verified by receptor binding assays.A total of 12 substitutions in the HA protein(N158D,N158S,A160 N,A160D,A160T,T163I,T163V,V190T,V190A,D193 N,D193G,and N231D)were predicted to prefer binding toα-2,6 receptors.Except for the V190T substitution,the other substitutions were demonstrated to display an affinity for preferential binding toα-2,6 receptors by receptor binding assays.Especially,the A160T substitution caused a significant upregulation of immune-response genes and an increased mortality rate in mice.Our findings provide novel insights into understanding the genetic basis of receptor preference of the H9N2 AIV.
基金Under the auspices of the Natural Science Foundation of China(No.32371875,32001249)。
摘要Stand age plays a crucial role in forest biomass estimation and carbon cycle modeling.Assessing the uncertainty of stand age prediction models and identifying the key driving factors in the modeling process have become major challenges in forestry research.In this study,we selected the Shaanxi-Gansu-Ningxia region of Northeast China as the research area and utilized multi-source datasets from the summer of 2019 to extract information on spectral,textural,climatic,water balance,and stand characteristics.By integrating the Random Forest(RF)model with Monte Carlo(MC)simulation,we constructed six regression models based on different combina-tions of features and evaluated the uncertainty of each model.Furthermore,we investigated the driving factors influencing stand age modeling by analyzing the effects of different types of features on age inversion.Model performance and accuracy were assessed using the root mean square error(RMSE),mean absolute error(MAE),and the coefficient of determination(R2),while the relative root mean square error(rRMSE)was employed to quantify model uncertainty.The results indicate that the scenarios with more obvious improve-ment in accuracy and effective reduction in uncertainty were Scenario 3 with the inclusion of climate and water balance information(RMSE=25.54 yr,MAE=18.03 yr,R2=0.51,rRMSE=19.17%)and Scenario 5 with the inclusion of stand characterization informa-tion(RMSE=18.47 yr,MAE=13.05 yr,R2=0.74,rRMSE=16.99%).Scenario 6,incorporating all feature types,achieved the highest accuracy(RMSE=17.60 yr,MAE=12.06 yr,R2=0.77,rRMSE=14.19%).In this study,elevation,minimum temperature,and diameter at breast height(DBH)emerged as the key drivers of stand-age modeling.The proposed method can be used to identify drivers and to quantify uncertainty in stand-age estimation,providing a useful reference for improving model accuracy and uncertainty assessment.
基金supported by the National Natural Science Foundation of China(No.51578263)the Jilin Provincial Department of Transport Project,China.
摘要During shield tunneling,ground deformation poses significant safety risks.The full optimization strategy ignores interactions between parameters,resulting in suboptimal performance in the pre-control of settlement in earth pressure balance shields.To address this problem,this paper proposes an integrated strategy that combines optimization and inversion,minimizing parameter interaction interference through adaptive adjustment of shield operation parameters.This mechanism performs an optimization search on the key operation parameters for settlement control,while the remaining operation parameters are predicted through inversion.Taking the Changchun Metro Line 6 project as an example,a bidirectional long short-term memory(Bi-LSTM)model enhanced by a multi-head self-attention(MHSA)mechanism is used to predict shield tunneling-induced settlement with spatiotemporal sequence dependency relationships.Particle swarm optimization and a random forest algorithm are used for optimization and inversion operations in the integrated mechanism,respectively.Subsequent ring position tests showed that the integrated mechanism-based adaptive adjustment strategy limited the average fluctuation of uncontrollable parameters to±13.95%compared to±34.27%for the full optimization strategy.The actual average settlement was only 3.81 mm compared to 4.72 mm for the full optimization strategy through collaborative parameter adjustment.The application validated the feasibility and applicability of the integrated mechanism,providing important references for the adaptive adjustment of shield parameters and tunnel construction automation.