Abstract Objective To explore the effects of governor vessel moxibustion-based characteristic nursing combined with meridian moxibustion on bone metabolism, bone mineral density (BMD), quality of life (QoL) and safety...Abstract Objective To explore the effects of governor vessel moxibustion-based characteristic nursing combined with meridian moxibustion on bone metabolism, bone mineral density (BMD), quality of life (QoL) and safety in patients with postmenopausal osteoporosis (PMOP). Methods A total of 96 patients with PMOP admitted to our hospital from January 2024 to December 2025 were selected and divided into a control group and an observation group by random number table method, with 48 cases in each group. The control group received routine nursing intervention for osteoporosis, while the observation group was additionally administered governor vessel moxibustion-based characteristic nursing combined with meridian moxibustion on the basis of routine nursing, with an intervention period of 12 weeks. Bone metabolism indicators (bone gla protein [BGP], C-terminal telopeptide of type I collagen [CTX-Ⅰ], bone alkaline phosphatase [BALP]), BMD of lumbar spine L1-L4, BMD of femoral neck, scores of the 36-item Short-Form Health Survey (SF-36) and incidence of adverse reactions were compared between the two groups before and after intervention. Results Before intervention, there were no statistically significant differences in bone metabolism indicators, BMD and QoL scores between the two groups (P>0.05). After intervention, the observation group showed significantly increased BGP level, significantly decreased CTX-Ⅰ and BALP levels, significantly improved BMD of lumbar spine and femoral neck, and higher scores in all SF-36 dimensions than the control group, with all differences statistically significant (P<0.05). The incidence of adverse reactions in the observation group was 6.25%, lower than 18.75% in the control group (P<0.05). Conclusion Governor vessel moxibustion-based characteristic nursing combined with meridian moxibustion can effectively improve bone metabolism, increase BMD, enhance QoL and ensure good safety in PMOP patients, which is worthy of clinical promotion.展开更多
Mesenchymal stem cell transplantation is a novel means of treating cerebral ischemiaeper- fusion, and can promote angiogenesis and neurological functional recovery. Acupuncture at Conception and Governor vessels also ...Mesenchymal stem cell transplantation is a novel means of treating cerebral ischemiaeper- fusion, and can promote angiogenesis and neurological functional recovery. Acupuncture at Conception and Governor vessels also has positive effects as a treatment for cerebral ischemia/ reperfusion. Therefore, we hypothesized that electro-acupuncture at Conception and Governor vessels plus mesenchymal stem cell transplantation may have better therapeutic effects on the promotion of angiogenesis and recovery of neurological function than either treatment alone. In the present study, human umbilical cord blood-derived mesenchymal stem cells were isolated, cultured, identified and intracranially transplanted into the striatum and subcortex of rats at 24 hours following cerebral ischemiaeperfusion. Subsequently, rats were electro-acupunctured at Conception and Governor vessels at 24 hours after transplantation. Modified neurological severity scores and immunohistochemistry findings revealed that the combined interventions of electro-acupuncture and mesenchymal stem cell transplantation clearly improved neurological impairment and up-regulated vascular endothelial growth factor expression around the isch- emic focus. The combined intervention provided a better outcome than mesenchymal stem cell transplantation alone. These findings demonstrate that electro-acupuncture at Conception and Governor vessels and mesenchymal stem cell transplantation have synergetic effects on promot- ing neurological function recovery and angiogenesis in rats after cerebral ischemiaeperfusion.展开更多
Objective: To explore influence of electroacupuncture(EA) therapy of tonifying the kidney and regulating governor vessel on amyloid beta(Aβ) related degradation enzymes in the hippocampus of a rat model of Alzhe...Objective: To explore influence of electroacupuncture(EA) therapy of tonifying the kidney and regulating governor vessel on amyloid beta(Aβ) related degradation enzymes in the hippocampus of a rat model of Alzheimer's disease(AD) induced by Aβ(1-42).Methods: Forty Wistar male rats were randomly divided into 4 groups: a normal group, a sham operation group, a model group and an EA group, 10 rats in each one. The rats in normal group were normally fed. The rats in sham operation group were bilaterally injected in the hippocampus with 5 μL of saline and they were normally fed after the injection. The rats in the model group and the EA group were bilaterally injected in the hippocampus with 5 μL of Aβ(1-42) on each side. Rats in the EA group received EA of 5 Hz continuous wave at the "Bǎihuì(百会 GV20)" and bilateral "Shènshū(肾俞 BL23)" for a duration of 15 min per time every day and continuously for 15 days. After 15 days, the hippocampal expression levels of insulin degrading enzyme(IDE), lipoprotein(LPL), transthyretin(TTR), apolipoprotein E(APoE),a2 macroglobulin(a2 M) and Aβ(1-42) of the 4 groups were tested by Western blot.Results: Compared with the sham operation group, the expression levels of IDE, LPL, TTR, APoE and a2 M in the hippocampus were significantly lower(P〈 0.05, P〈 0.01) and the expression of Aβ(1-42) was significantly higher(P〈 0.01) in the model group. Compared with the model group, the expression levels of IDE, LPL, TTR,APoE and a2 M in the hippocampus of these rats were significantly lower(P〈 0.05,P〈 0.01), the expression of Aβ(1-42) was significantly higher(P〈 0.01) in the EA group.Conclusion: EA therapy of tonifying the kidney and regulating governor vessel can enhance the expression of IDE, LPL, TTR, APoE, and a2 M in the hippocampus of AD rats injected by Aβ(1-42), and may consequently promote the degradation of aβ(1-42) to help improve the pathological manifestations of AD and therefore delay its progression.展开更多
Decompression is the major therapeutic strategy for acute spinal cord injury,but there is some debate about the time window for decompression following spinal cord injury.An important goal and challenge in the treatme...Decompression is the major therapeutic strategy for acute spinal cord injury,but there is some debate about the time window for decompression following spinal cord injury.An important goal and challenge in the treatment of spinal cord injury is inhibiting or reversing secondary injury.Governor Vessel electroacupuncture can improve symptoms of spinal cord injury by inhibiting cell apoptosis and improving the microenvironment of the injured spinal cord.In this study,Governor Vessel electroacupuncture combined with decompression at different time points was used to treat acute spinal cord injury.The rat models were established by inserting a balloon catheter into the atlanto-occipital space.The upper cervical spinal cord was compressed for 12 or 48 hours prior to decompression.Electroacupuncture was conducted at the acupoints Dazhui(GV14) and Baihui(GV 20)(2 Hz,15 minutes) once a day for 14 consecutive days.Compared with decompression alone,hind limb motor function recovery was superior after decompression for 12 and 48 hours combined with electroacupuncture.However,the recovery of motor function was not significantly different at 14 days after treatment in rats receiving decompression for 12 hours.Platelet-activating factor levels and caspase-9 protein expression were significantly reduced in rats receiving electroacupuncture compared with decompression alone.These findings indicate that compared with decompression alone,Governor Vessel electroacupuncture combined with delayed decompression(48 hours) is more effective in the treatment of upper cervical spinal cord injury.Governor Vessel electroacupuncture combined with early decompression(12 hours) can accelerate the recovery of nerve movement in rats with upper cervical spinal cord injury.Nevertheless,further studies are necessary to confirm whether it is possible to obtain additional benefit compared with early decompression alone.展开更多
OBJECTIVE: To investigate the combinatorial effects of conception and governor vessel electroacupuncture(EA) and human umbilical cord blood-derived mesenchymal stem cells(HUCB-MSCs) on pathomorphologic lesion and cell...OBJECTIVE: To investigate the combinatorial effects of conception and governor vessel electroacupuncture(EA) and human umbilical cord blood-derived mesenchymal stem cells(HUCB-MSCs) on pathomorphologic lesion and cellular apoptosis in rats with cerebral ischemiaeperfusion. METHODS: With the HUCB-MSCs isolated, cultured and identified and the models of cerebral ischemia-reperfusion established, the HUCB-MSCs of passage three were intracranially transplanted and the EA at conception and governor vessels was applied. The pathomorphologic lesion by hematoxylin-eosin staining and the cellular apoptosis by terminal deoxynucleotidyl transferase-mediated nick-end labeling method around the ischemic focus were observed. RESULTS: The cultured adherent HUCB-MSCs exhibited a spindle shape and expressed MSC-specific markers, with the cell purity and proliferation rate significantly increasing after the primary passage. HE staining showed that there were no pathological changes observed in the sham surgery group. However, in the PBS transplantation group, degeneration and necrosis of a great number of nerve cells were seen. In both the HUCB-MSCs transplantation group and the HUCB-MSCs transplantation + EA group, reparative changes of the pathomorphism of the tissue were found. Both combination treatment and simple MSCs treatment were able to improve the pathomorphorlogic lesion following cerebral ischemia and reduce the abnormal TUNEL-positive numbers, with former better than latter. CONCLUSION: HUCB-MSCs improve pathological lesions and inhibit the cellular apoptosis around the cerebral ischemic area. EA at conception and governor vessels also improve pathological lesion and inhibit the cellular apoptosis in rats treated with HUCB-MSCs transplantation, which effects were superior to that of simple HUCB-MSCs transplantation.展开更多
Objective: To observe the comprehensive curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain for post stroke depression associated with anxiety.Methods: Sixty-four patients ...Objective: To observe the comprehensive curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain for post stroke depression associated with anxiety.Methods: Sixty-four patients with post stroke depression associated with anxiety were randomly divided into 2 groups according to the random numbers generated by spss16.0 software, the group of acupuncture manipulation of regulating governor vessel and unblocking brain(group A) and medication group(group B), with 32 patients in each group. Acupuncture manipulation of regulating governor vessel and unblocking brain was performed in group A.Bǎihuì(百会GV 20), Shéntíng(神庭GV 24), Yǎmén(哑门GV 15) and Dànzhōng(膻中CV 17), Gānshū(肝俞BL 18). Xīnshū(心俞BL 15). Shènshū(肾俞BL 23),Tàichōng(太冲LR 3), Tàixī(太溪KI 3), Shénmén(神门HT 7) and Nèiguān(内关PC 6) were selected. The treatment was conducted for once a day, and 5 times a week. Escitalopram oxalate tablets were given orally to the patients in group B for once a day. The treatment was conducted for 8 consecutive weeks in each group. The scores of Hamilton depression scale(HAMD), Hamilton anxiety scale(HAMA), Barthel index(BI) and Fugl-Meyer assessment(FMA) in the two groups before and after treatment were compared.Results: Comparison with the same group before treatment, HAMD score and HAMA sore in the two groups after treatment for 4 weeks and 8 weeks were all obviously lower than that in the same group before treatment(all P〈0.01); after treatment for 8 weeks, B1 score and FMA score in the two groups were all significantly higher than that in the same group before treatment(all P〈0.01). Comparison between two groups after treatment. HAMD score and HAMA sore in group A after treatment for 4 weeks were significantly lower than that in group B(both P〈0.05); only the HAMA sore in group A after treatment for 8 weeks was lower than that in group B(P〈0.05), and there was no significant difference in HAMD score in the two groups(P〉0.05); after treatment for 8 weeks, FMA score in group A was obviously higher than that in group B(P〈0.05), and there was no significant difference in BI score in the two groups(P〉 0.05).Conclusion: The curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain on the anxiety state and motor function of the patients with post stroke depression is superior to that of escitalopram. With regard to the improvement of depression, this acupuncture manipulation was provided with the characteristic of rapid onset, and its long-term efficacy is equivalent to that of escitalopram. In terms of the improvement of activities of daily living, the curative effect of the two methods is equally well.展开更多
Objective To observe the effects on the range of motion (ROM) of ankle joint and muscular spasm of the lower limbs treated with Chinese massage for promoting the Governor Vessel, benefiting the kidney and strengthen...Objective To observe the effects on the range of motion (ROM) of ankle joint and muscular spasm of the lower limbs treated with Chinese massage for promoting the Governor Vessel, benefiting the kidney and strengthening the spleen combined with music therapy in infantile cerebral palsy (CP). Methods In 286 cases of spasmodic CP, 7 kinds of Chinese massage were adopted, named massage on acupoints to promote circulation of the Governor Vessel, massage for strengthening the spleen and benefiting qi, spine-pinching therapy, segmental massage, foot massage, massage for promoting the recovery of muscle strength and massage for promoting ROM of joints. Chinese massage was applied in musical background. Buddha music and five-element music of Chinese medicine (music of the Heart, Liver and Kidney Meridians) were optioned. The treatment was given once or twice a day and 30 days made one course. The angles of femoral adductor and dorsal flexion of foot as well as the score of composite spasticity scale (CSS) were observed before and after treatment so that the therapeutic effect was assessed. Results In 30 days of treatment, 106 cases (37. 1%) were effective markedly, 172 cases (60. 1%) effective and 8 cases (2.8%) failed. The angle of dorsal flexion of foot was (105.64± 12.66)° and (76.58± 9.89)° before and after treatment respectively; the angle of femoral adductor was (119.89±25.47)° and (158.99± 18.66)° before and after treatment respectively; the score of CSS was (12.39±2.56) and (7. 069 ± 2.97) before and after treatment respectivel, there was significant difference before and after treatment (all P〈0.01). Conclusion Chinese massage for promoting the Governor Vessel, benefiting the kidney and strengthening the spleen combined with music therapy brings the extremely active effect into play on the recovery of sitting, kneeling, standing and walking for children with CP.展开更多
Objective:To observe the clinical therapeutic effect of acupuncture at the dorsal section of the governor vessel in the patients with gastroesophageal reflux disease(GERD)combined with sleep disorder.Methods:A total o...Objective:To observe the clinical therapeutic effect of acupuncture at the dorsal section of the governor vessel in the patients with gastroesophageal reflux disease(GERD)combined with sleep disorder.Methods:A total of 30 patients with GERD combined with sleep disorder were included.Acupuncture was applied to the dorsal section of the governor vessel,inferior to the spinous process from T3 to T12,once every two days,3 times a week,totally for 8 weeks.Before and after treatment,the scores of the reflux disease questionnaire(RDQ)and the Pittsburgh sleep quality index(PSQI)were evaluated.After treatment,the clinical effect was evaluated in the patients.Results:The mean score of RDQ was 21.57±5.91 before treatment and was 3.75±4.92 after treatment,indicating the statistical significance(P<0.05).After treatment,the score of every dimension of PSQI was lower than that before treatment,indicating the statistical significance(P<0.05).Of 30 patients,23 cases were effective and the total effective rate was 76.7%.Conclusion:Acupuncture at the inferior of the spinous process from T3 to T12,on the dorsal section of the governor vessel,achieves the significant clinical effect on GERD combined with sleep disorder and this therapy deserves to be promoted in clinic.展开更多
Objective: To investigate the distribution and permeability of blood vessels on the Conception Vessel and the Governor Vessel in the physiological state. Methods: Evans blue (EB) solution was injected into the margina...Objective: To investigate the distribution and permeability of blood vessels on the Conception Vessel and the Governor Vessel in the physiological state. Methods: Evans blue (EB) solution was injected into the marginal ear vein of healthy rabbits. Three hours after injection, the rabbits were sacrificed and the skin on the Conception Vessel and the Governor Vessel and the corresponding bilateral non-channels was collected. EB was extracted with 7:3 acetone: physiological saline, and the absorbance of EB at each skin tissue was measured with a spectrophotometer. Results: The A value of EB absorbance at the Conception Vessel on the abdominal skin was lower than that of the corresponding bilateral non-channels with a statistically significant difference (P0.05). Conclusion: There were differences in capillary distribution and permeability between the Conception Vessel, the Governor Vessel and the corresponding bilateral non-meridians.展开更多
Objective To explore the effect of electroacupuncture at conception vessel and governor vessel on correlative signals of inflammatory response stressinjury-repair in cerebral ischemia reperfusion rats. Methods A total...Objective To explore the effect of electroacupuncture at conception vessel and governor vessel on correlative signals of inflammatory response stressinjury-repair in cerebral ischemia reperfusion rats. Methods A total of 216 rats were included in the experiment, of which 192 rats were randomly divided into four groups, including sham operation group(group A), model group(group B), governor vessel group(group C), and conception vessel and governor vessel group(group D), 48 rats in each group. The rats in each group were further divided into six sub-groups, including 12 h group, 24 h group, 48 h group, 72 h group, 96 h group and 144 h group. MCAO operation course was simulated in group A, and the common carotid artery, internal carotid artery and external carotid artery on the right side were exposed, without insertion of suture or treatment. After completion of modeling in group B, treatment was not conducted. After completion of modeling in group C, "Shuǐgōu(水沟 GV 26)", "Bǎihuì(百会 GV 20)" and "Dàzhuī(大椎 GV 14)" of governor vessel were selected, and electroacupuncture device was connected with "GV 14" and "GV 20". After completion of modeling in group D, "GV 26", "GV 20" and "GV 14" of governor vessel, and "Qìhǎi(气海 CV 6)", "Guānyuán(关元 CV 4)" and "Chéngjiāng(承浆 CV 24)" of conception vessel were selected; electroacupuncture device was connected with "GV 14" and "GV 20", "CV 4" and "CV 6". Neurological severity score was conducted.Enzyme linked immunosorbent assay(ELISA) was applied to determine the concentration of peripheral serum adrenocorticotropic hormone(ACTH) of rats, and immunohistochemical method was adopted to detect the expression levels of tumor necrosis factor α(TNF-α) and transforming growth factor β1(TGF-β1) in brain tissue of rats. The other 24 rats were also randomly divided into four groups mentioned above, 6 rats in each group, to detect cerebral ischemie volume. Results Compared with group B, the ischemia volume in brain tissue at 144 h after cerebral ischemia reperfusion decreased significantly in group C and group D(P〈0.05), and the ischemia volume in group D was less than that in group C(P〈0.05). The neurological impairment scores of group C and group D at all time points were lower than those of group B, and the differences were statistically significant(all P〈0.05). The scores of group D at all time points were lower than those of group C, and the differences since 24 h were statistically significant(all P〈0.05). Compared with group B, the excessive expression of ACTH was suppressed dynamically and generally in group C and group D(P〈0.05); the expression level of TNF-α was down-regulated and TGF-β1 was up-regulated as well in group C and group D(P〈0.05). The effect in group D was superior to that in group C. Conclusion Electroacupuncture at conception vessel and governor vessel can protect brain through the intervention of the expression of correlative signals of inflammatory response stress-injury-repair of cerebral ischemia reperfusion.展开更多
Objective: To report the clinical effect of traditional acupuncture and moxibustion in the treatment of neurogenic bladder.Methods: A single case of a 57-year-old female with neurogenic bladder retention of urine co...Objective: To report the clinical effect of traditional acupuncture and moxibustion in the treatment of neurogenic bladder.Methods: A single case of a 57-year-old female with neurogenic bladder retention of urine considering governor vessel in the use of acupuncture and moxibustion. Acupoints selected: Shenshū(肾俞BL 23),Pángguāngshū(膀胧俞 BL 28). Yāoyángguan(腰阳关GV 3), Mìngmén(命门 GV 4). Moxibustion was applied on Guānyuán(关元 CV4) at the same time.Results: After 6 times of treatment, the patient’s urination function return to normal, avoid the adverse effect of retention catheterization.Conclusion: It is suggested that the combination of acupuncture and moxibustion, and the integration of syndrome differentiation and disease differentiation can effectively treat retention of urine due to neurogenic bladder of patient with diabetes.展开更多
Objective To explore the effects of sliding-cup with different parameters on energy metabolism in the body by observing the effect of sliding-cup along the governor vessel on transcutaneous partial pressures of oxygen...Objective To explore the effects of sliding-cup with different parameters on energy metabolism in the body by observing the effect of sliding-cup along the governor vessel on transcutaneous partial pressures of oxygen and carbon dioxide in Mìngmén(命门 GV 4) in sub-healthy people. Methods A total of 10 sub-healthy adults at rest were observed and sliding-cup along the governor vessel were conducted with three different parameters, jar-pressure of –0.01~ –0.02 MPa with sliding-cup for 5 min, jar-pressure of –0.02~ –0.03 MPa with sliding-cup for 5 min and jar-pressure of –0.02~ –0.03 MPa with slidingcup for 3 min. Peri Flux System5000 PF5040 module was employed to monitor the changes of transcutaneous partial pressures of oxygen(tcp O2) and carbon dioxide(tcp CO2) in GV 4 at 0 min, 5 min, 10 min, 15 min, 20 min, 25 min and 30 min after sliding-cup with above different interventions in sub-healthy subjects. Results After sliding-cup, tcp O2 increased at first and then decreased over time; there was no difference in tcp O2 after sliding-cupping with different parameters(all P0.05). After sliding-cup, tcp CO2 decreased; there was no difference in tcp CO2 after sliding-cup with different parameters(all P0.05). Conclusion Sliding-cup has a sustained effect on the body and can speed up the energy metabolism in the body.展开更多
Objective To observe the effect of governor vessel moxibustion on improving cardiopulmonary fitness in patients with stable chronic obstructive pulmonary disease(COPD) of qi deficiency of lung and kidney.Methods A tot...Objective To observe the effect of governor vessel moxibustion on improving cardiopulmonary fitness in patients with stable chronic obstructive pulmonary disease(COPD) of qi deficiency of lung and kidney.Methods A total of 40 patients with stable COPD of qi deficiency of lung and kidney were randomized into an observation group(20 cases) and a control group(20 cases).展开更多
Objective To observe the clinical efficacy of moxibustion and acupuncture at acupoints of the governor vessel combined with repeated transcranial magnetic stimulation(rTMS)in the treatment of post-stroke fatigue(PSF)....Objective To observe the clinical efficacy of moxibustion and acupuncture at acupoints of the governor vessel combined with repeated transcranial magnetic stimulation(rTMS)in the treatment of post-stroke fatigue(PSF).Methods A total of 78 patients with PSF were randomized into an observation group(39 cases,1 case dropped out)and a control group(39 cases,1 case dropped out).The patients in bothh groups received conventional medical basic treatment.In the control group,rTMS was adopted,20 min each time.On the basis of the treatment in the control group,therapy of moxibustion and acupuncture at acupoints of the governor vessel was delivered in the observation group,Baihui(GV 20),Dazhui(GV 14),Shenting(GV 24),Fengfu(GV 16),Zhiyang(GV 9),Mingmen(GV 4)and Yaoyangguan(GV 3)were selected,Baihui(GV 20)was treated with moxibustion,Dazhui(GV 14)was treated with collateral-pricking,other acupointswere treated with conventional acupuncture,moxibustion and acupuncture were sustained for 30 min.The treatment in both groups was given once a day for continuous two weeks.Before and after treatment,the scores of fatigue severity scale(FSS),Pittsburgh sleep quality index(PSQI)and Fugl-Meyer motor function assessment(FMA)were observed,and the serum levels of Creactive protein(CRP),interleukin(IL)-1βand IL-6 were detected in both groups.Results After treatment,in the two groups,the FSS and PSQI scores,as well as the serum levels of CRP,IL-1βand IL-6 were decreased compared with those before treatment(P<0.05),while FMA scores were increased compared with those before treatment(P<0.05).After treatment,in the observation group,FSS and PSQI scores,as well as the serum levels of CRP,IL-1βand IL-6 were lower than those in the control group(P<0.05),while FMA score was higher than that in the control group(P<0.05).The serum levels of CRP,IL-1βand IL-6 were positively correlated with FSS score in the observation group(P<0.01).Conclusion Moxibustion and acupuncture at acupoints of the governor vessel combined with rTMS can effectively alleviate the fatigue,improve the sleep quality and limb function in PSF patients,whose mechanism on alleviating fatigue may be related to the down-regulation of serum inflammatory factors.展开更多
Objective:To observe the effect of Governor Vessel-unblocking and mind-calming acupuncture on insomnia and further develop the academic idea on Gao's lineage acupuncture.Methods:A total of 68 insomnia cases were ra...Objective:To observe the effect of Governor Vessel-unblocking and mind-calming acupuncture on insomnia and further develop the academic idea on Gao's lineage acupuncture.Methods:A total of 68 insomnia cases were randomly allocated into an acupuncture group(n=34) and a medication group(n=34) according to their sequences of consultation.Patients in the acupuncture group received acupuncture treatment once a day,5 d a week,for 4 weeks.Patients in the medication group took 1 mg of Estazolam before sleep for each dose,one dose a day,for 4 weeks.Before and after treatment,the sleep quality was evaluated using the Pittsburgh sleep quality index(PSQI),and the efficacy was assessed using the PSQI reductive rate.Results:After treatment,the global PSQI score and scores of each component in the acupuncture group were significantly decreased(all P〈0.01).The global PSQI score in the medication group was significantly decreased(P〈0.01).Except for sleep disturbance,scores of the rest of components were significantly decreased(P〈0.01 or P〈0.05).The between-group difference was statistically significant in global PSQI score(P〈0.01).Except for sleep latency and duration,scores of the sleep quality,efficiency,disturbance and daytime dysfunction in the acupuncture group were significantly lower than those in the medication group(all P〈0.05).In addition,the recovery and marked effect rate in the acupuncture group was significantly higher than that in the medication group(P〈0.05).Conclusion:The Governor Vessel-unblocking and mind-calming acupuncture is safe,reliable for insomnia and has better efficacy than Estazolam.展开更多
Objective:To observe the instant analgesic effect of Governor Vessel-regulating and collateral-unblocking acupuncture method in treating primary headache and to inherit and carry forward the academic achievements of G...Objective:To observe the instant analgesic effect of Governor Vessel-regulating and collateral-unblocking acupuncture method in treating primary headache and to inherit and carry forward the academic achievements of Gao's acupuncture school in Yanzhao(Hebei Province)area.Methods:Eighty eligible primary headache patients were randomized into an observation group and a control group following their visiting sequence,40 patients in each group.The observation group was intervened by Yanzhao Gao's Governor Vessel-regulating and collateral-unblocking acupuncture,and the control group was intervened by ordinary acupuncture method.The visual analogue scale(VAS)was used to evaluate the headache intensity before and after the first treatment session in the two groups,to compare the instant analgesic effect of the two acupuncture methods.Results:After the first treatment session,the VAS scores dropped significantly in both groups(both P〈0.05).The change of VAS score after the initial treatment in the observation group was significantly different from that in the control group(P〈0.05).The percentage of patients with headache completely vanished instantly after the first treatment was markedly higher in the observation group than that in the control group(P〈0.05).Conclusion:The two acupuncture methods both can produce a significant instant analgesic effect in treating primary headache,while Yanzhao Gao's Governor Vessel-regulating and collateral-unblocking acupuncture method is superior to ordinary acupuncture method.展开更多
Objective:To observe the clinical efficacy of herb-insulated moxibustion on the Governor Vessel in dog days of summer for postpartum pantalgia.Methods:A total of 64 patients with postpartum pantalgia were randomized i...Objective:To observe the clinical efficacy of herb-insulated moxibustion on the Governor Vessel in dog days of summer for postpartum pantalgia.Methods:A total of 64 patients with postpartum pantalgia were randomized into an observation group and a control group,with 32 cases in each group.Both groups were treated with herb-insulated moxibustion on the Governor Vessel.The control group was treated in non-dog days,and the observation group was treated in dog days of summer.Both groups were treated with moxibustion once every 3 d,3 times as one course of treatment,for a total of 3 courses.The range and degree of pain were evaluated by the 45-region body surface area score and visual analog scale(VAS)score before treatment,after treatment,1 month after treatment,and around the Winter Solstice.The revised fibromyalgia impact questionnaire(FIQR)was used to evaluate the quality of life of the patients.The clinical efficacy was compared between the two groups after treatment.Results:During the trial,there were 2 dropout cases in the observation group,and 2 cases were eliminated from the control group.After treatment,the total effective rate in the observation group was 93.3%,which was higher than 76.6%in the control group(P<0.05).Compared with before treatment,the number of pain sites and pain areas of the patients in both groups decreased after treatment,1 month after treatment,and around the Winter Solstice(P<0.05),and the FIQR score decreased(P<0.05).The score of each item in the observation group was lower than that in the control group(P<0.05).Compared with before treatment,the VAS score in the observation group decreased after treatment,1 month after treatment,and around the Winter Solstice(P<0.01),and was lower than that in the control group at the same time point(P<0.05).Conclusion:Herb-insulated moxibustion on the Governor Vessel can improve the range and degree of pain in patients with postpartum pantalgia and improve their quality of life.The total efficacy of the moxibustion performed in dog days is superior to that in non-dog days,and the effect lasts longer.展开更多
Governor Vessel is one of eight extraordinary Meridians, and been also called "the sea of Yang Meridians". It masters the Yin and Yang of the body cooperating with Conception Vessel. Acupoints on Governor Vessel hav...Governor Vessel is one of eight extraordinary Meridians, and been also called "the sea of Yang Meridians". It masters the Yin and Yang of the body cooperating with Conception Vessel. Acupoints on Governor Vessel have been used widely in clinic. The author expounded the functional feature of Yaoyangguan (GV 3), Mingmen (GV 4), Zhiyang (GV 9), Dazhui (GV 14) and Baihui (GV 20), which can show the characteristic of Governor Vessel and provide reference for clinical application.展开更多
Objective:To observe the clinical efficacy of row needling at the Governor Vessel on the head for poststroke insomnia,analyze the changes of sleep structure,serum amino acid neurotransmitters,vascular endothelial cell...Objective:To observe the clinical efficacy of row needling at the Governor Vessel on the head for poststroke insomnia,analyze the changes of sleep structure,serum amino acid neurotransmitters,vascular endothelial cell function and cognitive function,in order to explore the mechanism of this therapy.Methods:A total of 41 patients with poststroke insomnia were included in an observation group and treated with row needing at the Governor Vessel on the head;33 patients with poststroke insomnia were included in a control group and given routine acupuncture treatment.The patients in both groups were treated consecutively for one month.The efficacy was observed and the changes of related indicators were compared.Results:After treatment,the efficacy of the observation group was better than that of the control group(P<0.05).The sleep latency in the observation group was shorter than that in the control group(P<0.05);the total sleep duration,deep sleep duration,light sleep duration and rapid eye movement sleep duration in the observation group were significantly longer than those in the control group(P<0.05);the total waking duration and the waking times over 5 min were significantly less than those in the control group(P<0.05).The serum glutamic acid,γ-aminobutyric acid,calcitonin gene-related peptide,brain-derived neurotrophic factor,nerve growth factor and nitric oxide levels were significantly higher than those in the control group(P<0.01).The tumor necrosis factor-α,interleukin-6,bradykinin,and endothelin-1 levels were lower than those in the control group(P<0.01).The Pittsburgh sleep quality index score in the observation group was lower than that in the control group(P<0.01),and the mini-mental state examination score was higher than that in the control group(P<0.05).Conclusion:Row needling at the Governor Vessel on the head can effectively improve the sleep structure,cognitive function,and sleep quality of patients with poststroke insomnia.The possible mechanisms are regulating serum amino acid neurotransmitters and improving the function of vascular endothelial cells.展开更多
Moxibustion is an ancient therapeutic technique used in Chinese medicine. Governor Vessel moxibustion(GVM) was developed from long snake moxibustion, a popular technique used in China's Jiangsu and Zhejiang Provinc...Moxibustion is an ancient therapeutic technique used in Chinese medicine. Governor Vessel moxibustion(GVM) was developed from long snake moxibustion, a popular technique used in China's Jiangsu and Zhejiang Provinces, and is significantly more effective than general moxibustion. We aimed to review GVM, including its theoretical basis, choices of moxibustion points and materials, operation procedures, clinical applications, and contraindications. This information could increase the appropriate use of GVM and support further in-depth research.展开更多
摘要Abstract Objective To explore the effects of governor vessel moxibustion-based characteristic nursing combined with meridian moxibustion on bone metabolism, bone mineral density (BMD), quality of life (QoL) and safety in patients with postmenopausal osteoporosis (PMOP). Methods A total of 96 patients with PMOP admitted to our hospital from January 2024 to December 2025 were selected and divided into a control group and an observation group by random number table method, with 48 cases in each group. The control group received routine nursing intervention for osteoporosis, while the observation group was additionally administered governor vessel moxibustion-based characteristic nursing combined with meridian moxibustion on the basis of routine nursing, with an intervention period of 12 weeks. Bone metabolism indicators (bone gla protein [BGP], C-terminal telopeptide of type I collagen [CTX-Ⅰ], bone alkaline phosphatase [BALP]), BMD of lumbar spine L1-L4, BMD of femoral neck, scores of the 36-item Short-Form Health Survey (SF-36) and incidence of adverse reactions were compared between the two groups before and after intervention. Results Before intervention, there were no statistically significant differences in bone metabolism indicators, BMD and QoL scores between the two groups (P>0.05). After intervention, the observation group showed significantly increased BGP level, significantly decreased CTX-Ⅰ and BALP levels, significantly improved BMD of lumbar spine and femoral neck, and higher scores in all SF-36 dimensions than the control group, with all differences statistically significant (P<0.05). The incidence of adverse reactions in the observation group was 6.25%, lower than 18.75% in the control group (P<0.05). Conclusion Governor vessel moxibustion-based characteristic nursing combined with meridian moxibustion can effectively improve bone metabolism, increase BMD, enhance QoL and ensure good safety in PMOP patients, which is worthy of clinical promotion.
基金supported by the National Natural Science Foundation of China,No.81072877Key Laboratory Project of Condition and Platform Construction Plan of Shenzhen Scientific Research Fund,No.CXB201111250113AShenzhen Scientific and Technology Development Program,No.201203149
摘要Mesenchymal stem cell transplantation is a novel means of treating cerebral ischemiaeper- fusion, and can promote angiogenesis and neurological functional recovery. Acupuncture at Conception and Governor vessels also has positive effects as a treatment for cerebral ischemia/ reperfusion. Therefore, we hypothesized that electro-acupuncture at Conception and Governor vessels plus mesenchymal stem cell transplantation may have better therapeutic effects on the promotion of angiogenesis and recovery of neurological function than either treatment alone. In the present study, human umbilical cord blood-derived mesenchymal stem cells were isolated, cultured, identified and intracranially transplanted into the striatum and subcortex of rats at 24 hours following cerebral ischemiaeperfusion. Subsequently, rats were electro-acupunctured at Conception and Governor vessels at 24 hours after transplantation. Modified neurological severity scores and immunohistochemistry findings revealed that the combined interventions of electro-acupuncture and mesenchymal stem cell transplantation clearly improved neurological impairment and up-regulated vascular endothelial growth factor expression around the isch- emic focus. The combined intervention provided a better outcome than mesenchymal stem cell transplantation alone. These findings demonstrate that electro-acupuncture at Conception and Governor vessels and mesenchymal stem cell transplantation have synergetic effects on promot- ing neurological function recovery and angiogenesis in rats after cerebral ischemiaeperfusion.
基金Supported by National Natural Science Foundation of China Project:No.81473786
摘要Objective: To explore influence of electroacupuncture(EA) therapy of tonifying the kidney and regulating governor vessel on amyloid beta(Aβ) related degradation enzymes in the hippocampus of a rat model of Alzheimer's disease(AD) induced by Aβ(1-42).Methods: Forty Wistar male rats were randomly divided into 4 groups: a normal group, a sham operation group, a model group and an EA group, 10 rats in each one. The rats in normal group were normally fed. The rats in sham operation group were bilaterally injected in the hippocampus with 5 μL of saline and they were normally fed after the injection. The rats in the model group and the EA group were bilaterally injected in the hippocampus with 5 μL of Aβ(1-42) on each side. Rats in the EA group received EA of 5 Hz continuous wave at the "Bǎihuì(百会 GV20)" and bilateral "Shènshū(肾俞 BL23)" for a duration of 15 min per time every day and continuously for 15 days. After 15 days, the hippocampal expression levels of insulin degrading enzyme(IDE), lipoprotein(LPL), transthyretin(TTR), apolipoprotein E(APoE),a2 macroglobulin(a2 M) and Aβ(1-42) of the 4 groups were tested by Western blot.Results: Compared with the sham operation group, the expression levels of IDE, LPL, TTR, APoE and a2 M in the hippocampus were significantly lower(P〈 0.05, P〈 0.01) and the expression of Aβ(1-42) was significantly higher(P〈 0.01) in the model group. Compared with the model group, the expression levels of IDE, LPL, TTR,APoE and a2 M in the hippocampus of these rats were significantly lower(P〈 0.05,P〈 0.01), the expression of Aβ(1-42) was significantly higher(P〈 0.01) in the EA group.Conclusion: EA therapy of tonifying the kidney and regulating governor vessel can enhance the expression of IDE, LPL, TTR, APoE, and a2 M in the hippocampus of AD rats injected by Aβ(1-42), and may consequently promote the degradation of aβ(1-42) to help improve the pathological manifestations of AD and therefore delay its progression.
基金supported by the Capital Characteristic Clinical Application Research Projects of Beijing Municipal Science and Technology Plan of China,No.Z16110000516009
摘要Decompression is the major therapeutic strategy for acute spinal cord injury,but there is some debate about the time window for decompression following spinal cord injury.An important goal and challenge in the treatment of spinal cord injury is inhibiting or reversing secondary injury.Governor Vessel electroacupuncture can improve symptoms of spinal cord injury by inhibiting cell apoptosis and improving the microenvironment of the injured spinal cord.In this study,Governor Vessel electroacupuncture combined with decompression at different time points was used to treat acute spinal cord injury.The rat models were established by inserting a balloon catheter into the atlanto-occipital space.The upper cervical spinal cord was compressed for 12 or 48 hours prior to decompression.Electroacupuncture was conducted at the acupoints Dazhui(GV14) and Baihui(GV 20)(2 Hz,15 minutes) once a day for 14 consecutive days.Compared with decompression alone,hind limb motor function recovery was superior after decompression for 12 and 48 hours combined with electroacupuncture.However,the recovery of motor function was not significantly different at 14 days after treatment in rats receiving decompression for 12 hours.Platelet-activating factor levels and caspase-9 protein expression were significantly reduced in rats receiving electroacupuncture compared with decompression alone.These findings indicate that compared with decompression alone,Governor Vessel electroacupuncture combined with delayed decompression(48 hours) is more effective in the treatment of upper cervical spinal cord injury.Governor Vessel electroacupuncture combined with early decompression(12 hours) can accelerate the recovery of nerve movement in rats with upper cervical spinal cord injury.Nevertheless,further studies are necessary to confirm whether it is possible to obtain additional benefit compared with early decompression alone.
基金Supported by the National Natural Science Foundation of China(No.81072877)Shenzhen Municipal Science and Technology Research Development and Funds and Platform Construction Plan Key Laboratory Program(No.CXB201111250113A)Shenzhen Municipal Science and Technology Plan Project(No.201203149)
摘要OBJECTIVE: To investigate the combinatorial effects of conception and governor vessel electroacupuncture(EA) and human umbilical cord blood-derived mesenchymal stem cells(HUCB-MSCs) on pathomorphologic lesion and cellular apoptosis in rats with cerebral ischemiaeperfusion. METHODS: With the HUCB-MSCs isolated, cultured and identified and the models of cerebral ischemia-reperfusion established, the HUCB-MSCs of passage three were intracranially transplanted and the EA at conception and governor vessels was applied. The pathomorphologic lesion by hematoxylin-eosin staining and the cellular apoptosis by terminal deoxynucleotidyl transferase-mediated nick-end labeling method around the ischemic focus were observed. RESULTS: The cultured adherent HUCB-MSCs exhibited a spindle shape and expressed MSC-specific markers, with the cell purity and proliferation rate significantly increasing after the primary passage. HE staining showed that there were no pathological changes observed in the sham surgery group. However, in the PBS transplantation group, degeneration and necrosis of a great number of nerve cells were seen. In both the HUCB-MSCs transplantation group and the HUCB-MSCs transplantation + EA group, reparative changes of the pathomorphism of the tissue were found. Both combination treatment and simple MSCs treatment were able to improve the pathomorphorlogic lesion following cerebral ischemia and reduce the abnormal TUNEL-positive numbers, with former better than latter. CONCLUSION: HUCB-MSCs improve pathological lesions and inhibit the cellular apoptosis around the cerebral ischemic area. EA at conception and governor vessels also improve pathological lesion and inhibit the cellular apoptosis in rats treated with HUCB-MSCs transplantation, which effects were superior to that of simple HUCB-MSCs transplantation.
基金Supported by Project of Hebei Provincial Science and Technology Department:Clinical study of the acupuncture manipulation of regulating governor vessel andunblocking brain for treatment of dominant diseases of acupuncture-moxibustion":14277706D~~
摘要Objective: To observe the comprehensive curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain for post stroke depression associated with anxiety.Methods: Sixty-four patients with post stroke depression associated with anxiety were randomly divided into 2 groups according to the random numbers generated by spss16.0 software, the group of acupuncture manipulation of regulating governor vessel and unblocking brain(group A) and medication group(group B), with 32 patients in each group. Acupuncture manipulation of regulating governor vessel and unblocking brain was performed in group A.Bǎihuì(百会GV 20), Shéntíng(神庭GV 24), Yǎmén(哑门GV 15) and Dànzhōng(膻中CV 17), Gānshū(肝俞BL 18). Xīnshū(心俞BL 15). Shènshū(肾俞BL 23),Tàichōng(太冲LR 3), Tàixī(太溪KI 3), Shénmén(神门HT 7) and Nèiguān(内关PC 6) were selected. The treatment was conducted for once a day, and 5 times a week. Escitalopram oxalate tablets were given orally to the patients in group B for once a day. The treatment was conducted for 8 consecutive weeks in each group. The scores of Hamilton depression scale(HAMD), Hamilton anxiety scale(HAMA), Barthel index(BI) and Fugl-Meyer assessment(FMA) in the two groups before and after treatment were compared.Results: Comparison with the same group before treatment, HAMD score and HAMA sore in the two groups after treatment for 4 weeks and 8 weeks were all obviously lower than that in the same group before treatment(all P〈0.01); after treatment for 8 weeks, B1 score and FMA score in the two groups were all significantly higher than that in the same group before treatment(all P〈0.01). Comparison between two groups after treatment. HAMD score and HAMA sore in group A after treatment for 4 weeks were significantly lower than that in group B(both P〈0.05); only the HAMA sore in group A after treatment for 8 weeks was lower than that in group B(P〈0.05), and there was no significant difference in HAMD score in the two groups(P〉0.05); after treatment for 8 weeks, FMA score in group A was obviously higher than that in group B(P〈0.05), and there was no significant difference in BI score in the two groups(P〉 0.05).Conclusion: The curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain on the anxiety state and motor function of the patients with post stroke depression is superior to that of escitalopram. With regard to the improvement of depression, this acupuncture manipulation was provided with the characteristic of rapid onset, and its long-term efficacy is equivalent to that of escitalopram. In terms of the improvement of activities of daily living, the curative effect of the two methods is equally well.
摘要Objective To observe the effects on the range of motion (ROM) of ankle joint and muscular spasm of the lower limbs treated with Chinese massage for promoting the Governor Vessel, benefiting the kidney and strengthening the spleen combined with music therapy in infantile cerebral palsy (CP). Methods In 286 cases of spasmodic CP, 7 kinds of Chinese massage were adopted, named massage on acupoints to promote circulation of the Governor Vessel, massage for strengthening the spleen and benefiting qi, spine-pinching therapy, segmental massage, foot massage, massage for promoting the recovery of muscle strength and massage for promoting ROM of joints. Chinese massage was applied in musical background. Buddha music and five-element music of Chinese medicine (music of the Heart, Liver and Kidney Meridians) were optioned. The treatment was given once or twice a day and 30 days made one course. The angles of femoral adductor and dorsal flexion of foot as well as the score of composite spasticity scale (CSS) were observed before and after treatment so that the therapeutic effect was assessed. Results In 30 days of treatment, 106 cases (37. 1%) were effective markedly, 172 cases (60. 1%) effective and 8 cases (2.8%) failed. The angle of dorsal flexion of foot was (105.64± 12.66)° and (76.58± 9.89)° before and after treatment respectively; the angle of femoral adductor was (119.89±25.47)° and (158.99± 18.66)° before and after treatment respectively; the score of CSS was (12.39±2.56) and (7. 069 ± 2.97) before and after treatment respectivel, there was significant difference before and after treatment (all P〈0.01). Conclusion Chinese massage for promoting the Governor Vessel, benefiting the kidney and strengthening the spleen combined with music therapy brings the extremely active effect into play on the recovery of sitting, kneeling, standing and walking for children with CP.
摘要Objective:To observe the clinical therapeutic effect of acupuncture at the dorsal section of the governor vessel in the patients with gastroesophageal reflux disease(GERD)combined with sleep disorder.Methods:A total of 30 patients with GERD combined with sleep disorder were included.Acupuncture was applied to the dorsal section of the governor vessel,inferior to the spinous process from T3 to T12,once every two days,3 times a week,totally for 8 weeks.Before and after treatment,the scores of the reflux disease questionnaire(RDQ)and the Pittsburgh sleep quality index(PSQI)were evaluated.After treatment,the clinical effect was evaluated in the patients.Results:The mean score of RDQ was 21.57±5.91 before treatment and was 3.75±4.92 after treatment,indicating the statistical significance(P<0.05).After treatment,the score of every dimension of PSQI was lower than that before treatment,indicating the statistical significance(P<0.05).Of 30 patients,23 cases were effective and the total effective rate was 76.7%.Conclusion:Acupuncture at the inferior of the spinous process from T3 to T12,on the dorsal section of the governor vessel,achieves the significant clinical effect on GERD combined with sleep disorder and this therapy deserves to be promoted in clinic.
基金supported by the National Key Basic Research Development Project (No.2005CB523306)
摘要Objective: To investigate the distribution and permeability of blood vessels on the Conception Vessel and the Governor Vessel in the physiological state. Methods: Evans blue (EB) solution was injected into the marginal ear vein of healthy rabbits. Three hours after injection, the rabbits were sacrificed and the skin on the Conception Vessel and the Governor Vessel and the corresponding bilateral non-channels was collected. EB was extracted with 7:3 acetone: physiological saline, and the absorbance of EB at each skin tissue was measured with a spectrophotometer. Results: The A value of EB absorbance at the Conception Vessel on the abdominal skin was lower than that of the corresponding bilateral non-channels with a statistically significant difference (P0.05). Conclusion: There were differences in capillary distribution and permeability between the Conception Vessel, the Governor Vessel and the corresponding bilateral non-meridians.
基金Supported by Shenzhen Municipal Scientific and Technological Innovation Committee:JCYJ 20140408152909270Project of Shenzhen Municipal Key Laboratory of Technical Research and Development Fund Conditions and Platform Construction Plan:CXB 201111250113A
摘要Objective To explore the effect of electroacupuncture at conception vessel and governor vessel on correlative signals of inflammatory response stressinjury-repair in cerebral ischemia reperfusion rats. Methods A total of 216 rats were included in the experiment, of which 192 rats were randomly divided into four groups, including sham operation group(group A), model group(group B), governor vessel group(group C), and conception vessel and governor vessel group(group D), 48 rats in each group. The rats in each group were further divided into six sub-groups, including 12 h group, 24 h group, 48 h group, 72 h group, 96 h group and 144 h group. MCAO operation course was simulated in group A, and the common carotid artery, internal carotid artery and external carotid artery on the right side were exposed, without insertion of suture or treatment. After completion of modeling in group B, treatment was not conducted. After completion of modeling in group C, "Shuǐgōu(水沟 GV 26)", "Bǎihuì(百会 GV 20)" and "Dàzhuī(大椎 GV 14)" of governor vessel were selected, and electroacupuncture device was connected with "GV 14" and "GV 20". After completion of modeling in group D, "GV 26", "GV 20" and "GV 14" of governor vessel, and "Qìhǎi(气海 CV 6)", "Guānyuán(关元 CV 4)" and "Chéngjiāng(承浆 CV 24)" of conception vessel were selected; electroacupuncture device was connected with "GV 14" and "GV 20", "CV 4" and "CV 6". Neurological severity score was conducted.Enzyme linked immunosorbent assay(ELISA) was applied to determine the concentration of peripheral serum adrenocorticotropic hormone(ACTH) of rats, and immunohistochemical method was adopted to detect the expression levels of tumor necrosis factor α(TNF-α) and transforming growth factor β1(TGF-β1) in brain tissue of rats. The other 24 rats were also randomly divided into four groups mentioned above, 6 rats in each group, to detect cerebral ischemie volume. Results Compared with group B, the ischemia volume in brain tissue at 144 h after cerebral ischemia reperfusion decreased significantly in group C and group D(P〈0.05), and the ischemia volume in group D was less than that in group C(P〈0.05). The neurological impairment scores of group C and group D at all time points were lower than those of group B, and the differences were statistically significant(all P〈0.05). The scores of group D at all time points were lower than those of group C, and the differences since 24 h were statistically significant(all P〈0.05). Compared with group B, the excessive expression of ACTH was suppressed dynamically and generally in group C and group D(P〈0.05); the expression level of TNF-α was down-regulated and TGF-β1 was up-regulated as well in group C and group D(P〈0.05). The effect in group D was superior to that in group C. Conclusion Electroacupuncture at conception vessel and governor vessel can protect brain through the intervention of the expression of correlative signals of inflammatory response stress-injury-repair of cerebral ischemia reperfusion.
摘要Objective: To report the clinical effect of traditional acupuncture and moxibustion in the treatment of neurogenic bladder.Methods: A single case of a 57-year-old female with neurogenic bladder retention of urine considering governor vessel in the use of acupuncture and moxibustion. Acupoints selected: Shenshū(肾俞BL 23),Pángguāngshū(膀胧俞 BL 28). Yāoyángguan(腰阳关GV 3), Mìngmén(命门 GV 4). Moxibustion was applied on Guānyuán(关元 CV4) at the same time.Results: After 6 times of treatment, the patient’s urination function return to normal, avoid the adverse effect of retention catheterization.Conclusion: It is suggested that the combination of acupuncture and moxibustion, and the integration of syndrome differentiation and disease differentiation can effectively treat retention of urine due to neurogenic bladder of patient with diabetes.
基金Suported by Tianjin Municipal Administration of Traditional Chinese Medicine:11028
摘要Objective To explore the effects of sliding-cup with different parameters on energy metabolism in the body by observing the effect of sliding-cup along the governor vessel on transcutaneous partial pressures of oxygen and carbon dioxide in Mìngmén(命门 GV 4) in sub-healthy people. Methods A total of 10 sub-healthy adults at rest were observed and sliding-cup along the governor vessel were conducted with three different parameters, jar-pressure of –0.01~ –0.02 MPa with sliding-cup for 5 min, jar-pressure of –0.02~ –0.03 MPa with sliding-cup for 5 min and jar-pressure of –0.02~ –0.03 MPa with slidingcup for 3 min. Peri Flux System5000 PF5040 module was employed to monitor the changes of transcutaneous partial pressures of oxygen(tcp O2) and carbon dioxide(tcp CO2) in GV 4 at 0 min, 5 min, 10 min, 15 min, 20 min, 25 min and 30 min after sliding-cup with above different interventions in sub-healthy subjects. Results After sliding-cup, tcp O2 increased at first and then decreased over time; there was no difference in tcp O2 after sliding-cupping with different parameters(all P0.05). After sliding-cup, tcp CO2 decreased; there was no difference in tcp CO2 after sliding-cup with different parameters(all P0.05). Conclusion Sliding-cup has a sustained effect on the body and can speed up the energy metabolism in the body.
摘要Objective To observe the effect of governor vessel moxibustion on improving cardiopulmonary fitness in patients with stable chronic obstructive pulmonary disease(COPD) of qi deficiency of lung and kidney.Methods A total of 40 patients with stable COPD of qi deficiency of lung and kidney were randomized into an observation group(20 cases) and a control group(20 cases).
摘要Objective To observe the clinical efficacy of moxibustion and acupuncture at acupoints of the governor vessel combined with repeated transcranial magnetic stimulation(rTMS)in the treatment of post-stroke fatigue(PSF).Methods A total of 78 patients with PSF were randomized into an observation group(39 cases,1 case dropped out)and a control group(39 cases,1 case dropped out).The patients in bothh groups received conventional medical basic treatment.In the control group,rTMS was adopted,20 min each time.On the basis of the treatment in the control group,therapy of moxibustion and acupuncture at acupoints of the governor vessel was delivered in the observation group,Baihui(GV 20),Dazhui(GV 14),Shenting(GV 24),Fengfu(GV 16),Zhiyang(GV 9),Mingmen(GV 4)and Yaoyangguan(GV 3)were selected,Baihui(GV 20)was treated with moxibustion,Dazhui(GV 14)was treated with collateral-pricking,other acupointswere treated with conventional acupuncture,moxibustion and acupuncture were sustained for 30 min.The treatment in both groups was given once a day for continuous two weeks.Before and after treatment,the scores of fatigue severity scale(FSS),Pittsburgh sleep quality index(PSQI)and Fugl-Meyer motor function assessment(FMA)were observed,and the serum levels of Creactive protein(CRP),interleukin(IL)-1βand IL-6 were detected in both groups.Results After treatment,in the two groups,the FSS and PSQI scores,as well as the serum levels of CRP,IL-1βand IL-6 were decreased compared with those before treatment(P<0.05),while FMA scores were increased compared with those before treatment(P<0.05).After treatment,in the observation group,FSS and PSQI scores,as well as the serum levels of CRP,IL-1βand IL-6 were lower than those in the control group(P<0.05),while FMA score was higher than that in the control group(P<0.05).The serum levels of CRP,IL-1βand IL-6 were positively correlated with FSS score in the observation group(P<0.01).Conclusion Moxibustion and acupuncture at acupoints of the governor vessel combined with rTMS can effectively alleviate the fatigue,improve the sleep quality and limb function in PSF patients,whose mechanism on alleviating fatigue may be related to the down-regulation of serum inflammatory factors.
基金supported by Project of Hebei Provincial Administration of Traditional Chinese Medicine(No.2015011)~~
摘要Objective:To observe the effect of Governor Vessel-unblocking and mind-calming acupuncture on insomnia and further develop the academic idea on Gao's lineage acupuncture.Methods:A total of 68 insomnia cases were randomly allocated into an acupuncture group(n=34) and a medication group(n=34) according to their sequences of consultation.Patients in the acupuncture group received acupuncture treatment once a day,5 d a week,for 4 weeks.Patients in the medication group took 1 mg of Estazolam before sleep for each dose,one dose a day,for 4 weeks.Before and after treatment,the sleep quality was evaluated using the Pittsburgh sleep quality index(PSQI),and the efficacy was assessed using the PSQI reductive rate.Results:After treatment,the global PSQI score and scores of each component in the acupuncture group were significantly decreased(all P〈0.01).The global PSQI score in the medication group was significantly decreased(P〈0.01).Except for sleep disturbance,scores of the rest of components were significantly decreased(P〈0.01 or P〈0.05).The between-group difference was statistically significant in global PSQI score(P〈0.01).Except for sleep latency and duration,scores of the sleep quality,efficiency,disturbance and daytime dysfunction in the acupuncture group were significantly lower than those in the medication group(all P〈0.05).In addition,the recovery and marked effect rate in the acupuncture group was significantly higher than that in the medication group(P〈0.05).Conclusion:The Governor Vessel-unblocking and mind-calming acupuncture is safe,reliable for insomnia and has better efficacy than Estazolam.
基金supported by Projects of Hebei Provincial Administration of Traditional Chinese Medicine,No.2014038,No.2015145~
摘要Objective:To observe the instant analgesic effect of Governor Vessel-regulating and collateral-unblocking acupuncture method in treating primary headache and to inherit and carry forward the academic achievements of Gao's acupuncture school in Yanzhao(Hebei Province)area.Methods:Eighty eligible primary headache patients were randomized into an observation group and a control group following their visiting sequence,40 patients in each group.The observation group was intervened by Yanzhao Gao's Governor Vessel-regulating and collateral-unblocking acupuncture,and the control group was intervened by ordinary acupuncture method.The visual analogue scale(VAS)was used to evaluate the headache intensity before and after the first treatment session in the two groups,to compare the instant analgesic effect of the two acupuncture methods.Results:After the first treatment session,the VAS scores dropped significantly in both groups(both P〈0.05).The change of VAS score after the initial treatment in the observation group was significantly different from that in the control group(P〈0.05).The percentage of patients with headache completely vanished instantly after the first treatment was markedly higher in the observation group than that in the control group(P〈0.05).Conclusion:The two acupuncture methods both can produce a significant instant analgesic effect in treating primary headache,while Yanzhao Gao's Governor Vessel-regulating and collateral-unblocking acupuncture method is superior to ordinary acupuncture method.
摘要Objective:To observe the clinical efficacy of herb-insulated moxibustion on the Governor Vessel in dog days of summer for postpartum pantalgia.Methods:A total of 64 patients with postpartum pantalgia were randomized into an observation group and a control group,with 32 cases in each group.Both groups were treated with herb-insulated moxibustion on the Governor Vessel.The control group was treated in non-dog days,and the observation group was treated in dog days of summer.Both groups were treated with moxibustion once every 3 d,3 times as one course of treatment,for a total of 3 courses.The range and degree of pain were evaluated by the 45-region body surface area score and visual analog scale(VAS)score before treatment,after treatment,1 month after treatment,and around the Winter Solstice.The revised fibromyalgia impact questionnaire(FIQR)was used to evaluate the quality of life of the patients.The clinical efficacy was compared between the two groups after treatment.Results:During the trial,there were 2 dropout cases in the observation group,and 2 cases were eliminated from the control group.After treatment,the total effective rate in the observation group was 93.3%,which was higher than 76.6%in the control group(P<0.05).Compared with before treatment,the number of pain sites and pain areas of the patients in both groups decreased after treatment,1 month after treatment,and around the Winter Solstice(P<0.05),and the FIQR score decreased(P<0.05).The score of each item in the observation group was lower than that in the control group(P<0.05).Compared with before treatment,the VAS score in the observation group decreased after treatment,1 month after treatment,and around the Winter Solstice(P<0.01),and was lower than that in the control group at the same time point(P<0.05).Conclusion:Herb-insulated moxibustion on the Governor Vessel can improve the range and degree of pain in patients with postpartum pantalgia and improve their quality of life.The total efficacy of the moxibustion performed in dog days is superior to that in non-dog days,and the effect lasts longer.
摘要Governor Vessel is one of eight extraordinary Meridians, and been also called "the sea of Yang Meridians". It masters the Yin and Yang of the body cooperating with Conception Vessel. Acupoints on Governor Vessel have been used widely in clinic. The author expounded the functional feature of Yaoyangguan (GV 3), Mingmen (GV 4), Zhiyang (GV 9), Dazhui (GV 14) and Baihui (GV 20), which can show the characteristic of Governor Vessel and provide reference for clinical application.
摘要Objective:To observe the clinical efficacy of row needling at the Governor Vessel on the head for poststroke insomnia,analyze the changes of sleep structure,serum amino acid neurotransmitters,vascular endothelial cell function and cognitive function,in order to explore the mechanism of this therapy.Methods:A total of 41 patients with poststroke insomnia were included in an observation group and treated with row needing at the Governor Vessel on the head;33 patients with poststroke insomnia were included in a control group and given routine acupuncture treatment.The patients in both groups were treated consecutively for one month.The efficacy was observed and the changes of related indicators were compared.Results:After treatment,the efficacy of the observation group was better than that of the control group(P<0.05).The sleep latency in the observation group was shorter than that in the control group(P<0.05);the total sleep duration,deep sleep duration,light sleep duration and rapid eye movement sleep duration in the observation group were significantly longer than those in the control group(P<0.05);the total waking duration and the waking times over 5 min were significantly less than those in the control group(P<0.05).The serum glutamic acid,γ-aminobutyric acid,calcitonin gene-related peptide,brain-derived neurotrophic factor,nerve growth factor and nitric oxide levels were significantly higher than those in the control group(P<0.01).The tumor necrosis factor-α,interleukin-6,bradykinin,and endothelin-1 levels were lower than those in the control group(P<0.01).The Pittsburgh sleep quality index score in the observation group was lower than that in the control group(P<0.01),and the mini-mental state examination score was higher than that in the control group(P<0.05).Conclusion:Row needling at the Governor Vessel on the head can effectively improve the sleep structure,cognitive function,and sleep quality of patients with poststroke insomnia.The possible mechanisms are regulating serum amino acid neurotransmitters and improving the function of vascular endothelial cells.
基金Supported by the National Special Science and Technology Program on Major Infectious Diseases of China(N o.2012ZX10005010-001 and No.2013ZX10005001-001)Research Project for Practice Development of National Traditional Chinese Medicine Clinical Research Bases,China(No.JDZX2012023)+1 种基金Henan Province Colleges and Universities Key Youth Teachers Scheme,China(No.2013GGJS-095)Henan Province Basic and Advanced Technology Research Project,China(No.132300413215)
摘要Moxibustion is an ancient therapeutic technique used in Chinese medicine. Governor Vessel moxibustion(GVM) was developed from long snake moxibustion, a popular technique used in China's Jiangsu and Zhejiang Provinces, and is significantly more effective than general moxibustion. We aimed to review GVM, including its theoretical basis, choices of moxibustion points and materials, operation procedures, clinical applications, and contraindications. This information could increase the appropriate use of GVM and support further in-depth research.