期刊文献+
共找到701篇文章
< 1 2 36 >
每页显示 20 50 100
Novel therapeutic strategies for osteoarthritis:from mechanistic insights to precision medicine 认领 引用
1
作者 Muhammad Umar Ziling Wang +4 位作者 Jingwen Li Zhen Li Gang Li Liping Tong Di Chen 《Bone Research》 SCIE CAS CSCD 2026年第3期723-741,共19页
Osteoarthritis(OA)is a prevalent chronic degenerative joint disease that significantly impacts the quality of life for over 500 million individuals affected.OA is increasingly recognized as a whole-joint disorder char... Osteoarthritis(OA)is a prevalent chronic degenerative joint disease that significantly impacts the quality of life for over 500 million individuals affected.OA is increasingly recognized as a whole-joint disorder characterized by complex biochemical and cellular changes across various joint tissues.However,traditional approaches such as nonsteroidal anti-inflammatory drugs(NSAIDs)and corticosteroids often fall short in halting disease progression or restoring joint function.Thereby,recent innovations in OA management are focused on underlying pathophysiology,driving the development of regenerative therapies,targeted antiinflammatory agents and senolytic or senomorphic approaches.Accordingly,this paper reviews current progress in these areas by integrating evidence from clinical and pre-clinical studies to clarify therapeutic limitations,unresolved mechanistic and phenotypic gaps and the emerging strategies required to advance disease-modifying therapy in OA.It further outlines pathways toward precision,phenotype-aligned interventions,an integration that current literature has not yet consolidated. 展开更多
关键词 targeted anti inflammatory agents biochemical cellular changes osteoarthritis chronic degenerative joint disease mechanistic insights regenerative therapies senolytic approaches precision medicine
暂未订购 下载PDF
Genomic insights into the survival code of karst plants 认领 引用
2
作者 Xiongfang Liu Yongpeng Ma 《Plant Diversity》 SCIE CAS CSCD 2026年第2期227-230,共4页
Karst landscapes are developed on soluble rocks(primarily limestone),covering about 10-15%of Earth’s ice-free land surface(Ford and Williams,2007).Their unique geological properties have given rise to complex,heterog... Karst landscapes are developed on soluble rocks(primarily limestone),covering about 10-15%of Earth’s ice-free land surface(Ford and Williams,2007).Their unique geological properties have given rise to complex,heterogeneous,and“island-like”habitats that,combined with periodic drought,high calcium,and lownutrient stresses,foster high species diversity and endemism(Clements et al.,2006;Hao et al.,2015;Oliver et al.,2017;Monro et al.,2018).These conditions make karst ecosystems ideal“natural laboratories”for studying speciation and adaptive evolution(Clements et al.,2006;Oliver et al.,2017). 展开更多
关键词 soluble rocks soluble rocks primarily karst ecosystems genomic insights survival code karst plants limestone ice free land surface
暂未订购 下载PDF
从Tech Insights公司被制裁看如何在激烈的国际竞争中合法使用技术情报 认领 引用
3
作者 彭靖里 《竞争情报》 2026年第2期2-9,共8页
在中美科技竞争加剧和全球半导体产业战略博弈日益深化的背景下,技术情报活动的边界与风险已成为国际社会高度关注的议题。2025年,中国商务部将加拿大公司Tech Insights及其关联实体列入“不可靠实体清单”,标志着中国在半导体领域的反... 在中美科技竞争加剧和全球半导体产业战略博弈日益深化的背景下,技术情报活动的边界与风险已成为国际社会高度关注的议题。2025年,中国商务部将加拿大公司Tech Insights及其关联实体列入“不可靠实体清单”,标志着中国在半导体领域的反制措施由硬件与设备层面进一步延伸至技术情报与信息流动层面。此举引发了业界和学术界的广泛讨论。本文以Tech Insights被制裁事件为切入点,在梳理其业务模式与发展轨迹的基础上,探讨其在芯片逆向工程和技术情报服务方面的做法如何偏离国际公认的商业规范和职业道德,并分析这些做法的深层驱动因素及其对全球半导体创新生态系统及产业链和供应链安全带来的不利影响。文章指出,在大国竞争持续升级和技术民族主义势头渐起的背景下,传统上被视为商业中立的技术情报活动正愈加被工具化,并被纳入战略竞争框架。在这种情况下,仅依靠市场机制不足以化解安全与发展之间日益加剧的矛盾。本文着眼于如何在日趋激烈的国际竞争环境中合法合规地开展技术情报活动,提出有针对性的政策建议。文章强调,必须加快建立符合全球化趋势、以互利原则为基础的国家级竞争情报国际监管框架,这将为维护公平竞争和促进国际科技合作提供关键支持,具有重要的现实意义和政策价值。 展开更多
关键词 Tech Insights 技术情报 国际竞争 合法使用 风险
暂未订购 下载PDF
Chengdu’s Real Estate Market(2019-2024):An Integrated Framework for Data-Driven Insights and Policy Analysis 认领 引用
4
作者 HU Xiao WU Jing +1 位作者 WANG Yan JIANG Xinyi 《Cultural and Religious Studies》 2026年第1期26-42,共17页
This study integrates multiple sources of data(transaction data,policy text,public opinion data)with visualization techniques(such as heat maps,time-series trend charts,3D building brochures)to construct an analysis f... This study integrates multiple sources of data(transaction data,policy text,public opinion data)with visualization techniques(such as heat maps,time-series trend charts,3D building brochures)to construct an analysis framework for the Chengdu real estate market.By using the Adaptive Neuro-Fuzzy Inference System(ANFIS)prediction model,spatial GIS(Geographic Information System analysis)analysis,and interactive dashboards,this study reveals market differentiation,policy impacts,and changes in demand structure,thereby providing decision support for the government,enterprises,and homebuyers. 展开更多
关键词 Chengdu City real estate market data-driven insights policy analysis
暂未订购 下载PDF
Geothermal Energy in Jordan:Public Perception and Expert Insights from a National Survey 认领 引用
5
作者 Rashed Amireh Khaled Tarawneh +1 位作者 Feras Fraige Awwad Titi 《Journal of Geoscience and Environment Protection》 2026年第1期311-336,共26页
Jordan possesses considerable geothermal resources,predominantly within the low-enthalpy range(generally below 100˚C),which are well suited for directuse applications such as space heating,greenhouse agriculture,aquac... Jordan possesses considerable geothermal resources,predominantly within the low-enthalpy range(generally below 100˚C),which are well suited for directuse applications such as space heating,greenhouse agriculture,aquaculture,and balneological activities rather than large-scale electricity generation.These resources occur mainly as hot springs and geothermal wells distributed across several geothermal fields,with temperatures ranging from approximately 27˚C to 70˚C.Despite this potential,geothermal energy remains largely underutilized within Jordan’s national energy mix.This study investigates public perception and expert perspectives on geothermal energy as a pathway toward sustainable development in Jordan.A national survey involving 418 respondents was conducted to assess public awareness,acceptance,and willingness to adopt geothermal and other renewable energy technologies.The results indicate strong public interest in renewable energy utilization,although economic constraints,limited infrastructure,and insufficient institutional support remain key barriers.Complementary interviews with renewable energy experts confirm Jordan’s substantial geothermal potential while emphasizing the need for enhanced community awareness,supportive policy frameworks,and targeted investment.The findings highlight geothermal energy as a viable and sustainable solution for addressing Jordan’s energy challenges,particularly in reducing energy costs,supporting sustainable agriculture,and improving energy security.To fully realize these benefits,strategic measures are required,including regulatory modernization,investment incentives,stakeholder collaboration,and public outreach initiatives.Overall,geothermal energy emerges as an economically feasible and environmentally sustainable component of Jordan’s long-term energy transition strategy. 展开更多
关键词 Geothermal Energy Sustainable Development Public Perception Expert Insights Renewable Energy Policy Jordan
Genomic insights into the domestication and genetic basis of yield in papaya 认领 引用 被引量:4
6
作者 Min Yang Xiangdong Kong +6 位作者 Chenping Zhou Ruibin Kuang Xiaming Wu Chuanhe Liu Han He Ze Xu Yuerong Wei 《Horticulture Research》 SCIE CSCD 2025年第5期337-351,共15页
Papaya(Carica papaya L.)is an important tropical and subtropical fruit crop,and understanding its genome is essential for breeding.In this study,we assembled a high-quality genome of 344.17 Mb for the newly cultivated... Papaya(Carica papaya L.)is an important tropical and subtropical fruit crop,and understanding its genome is essential for breeding.In this study,we assembled a high-quality genome of 344.17 Mb for the newly cultivated papaya‘Zihui’,which contains 22250 proteincoding genes.By integrating 201 resequenced papaya genomes,we identified four distinct papaya groups and a 34 Mb genomic region with strong domestication selection signals.Within these regions,two key genes associated with papaya yield were discovered:Cp_zihui06549,encoding a leucine-rich receptor-like protein kinase,and Cp_zihui06768,encoding the accumulation of photosystem one 1(APO1)protein.Heterologous expression of Cp_zihui06549 in tomato confirmed that the total number of fruits in transgenic lines more than doubled compared to wild-type plants,resulting in a significant yield increase.Furthermore,we constructed a pan-genome of papaya and obtained a 77.41 Mb nonreference sequence containing 1543 genes.Within this pan-genome,2483 variable genes,we detected,including four genes annotated as the‘terpene synthase activity’Gene Ontology term,which were lost in cultivars during domestication.Finally,gene retention analyses were performed using gene presence and absence variation data and differentially expressed genes across various tissues and organs.This study provides valuable insights into the genes and loci associated with phenotypes and domestication processes,laying a solid foundation for future papaya breeding efforts. 展开更多
关键词 domestication selection genomic insights understanding its genome yield papaya integrating resequenced genetic basis domestication
暂未订购 下载PDF
Molecular insights into TT2-type MYB regulators illuminate the complexity of floral flavonoids biosynthesis in Freesia hybrida 认领 引用 被引量:1
7
作者 Xiaotong Shan Deyu Zhuang +10 位作者 Ruifang Gao Meng Qiu Liudi Zhou Jia Zhang Yanan Wang Qi Zhang Niu Zhai Guoyun Xu Li Wang Yueqing Li Xiang Gao 《Horticulture Research》 SCIE CSCD 2025年第3期67-79,共13页
Proanthocyanidins(PAs),anthocyanins,and flavonols are key flavonoids that play diverse roles in plant physiology and human health.Despite originating from a shared biosynthetic pathway,the regulatory mechanisms of PA ... Proanthocyanidins(PAs),anthocyanins,and flavonols are key flavonoids that play diverse roles in plant physiology and human health.Despite originating from a shared biosynthetic pathway,the regulatory mechanisms of PA biosynthesis and the cooperative regulation of different kinds of flavonoids remain elusive,particularly in flower tissues or organs.Here,we elucidated the regulatory network governing PA biosynthesis in Freesia hybrida‘Red River®’by characterizing four TT2-type MYB transcription factors,designated FhMYBPAs.Phylogenetic analysis,subcellular localization,and transactivation assays predicted their roles as PA-related activators.Pearson correlation analysis revealed significant correlations between FhMYBPAs and PA accumulation in various floral tissues and development stages.Functional studies demonstrated that FhMYBPAs activated PA biosynthesis by directly binding to the promoters of target genes,which can be enhanced by FhTT8L.Additionally,a hierarchical and feedback regulatory model involving FhTTG1,FhMYB27,and FhMYBx was proposed for PA biosynthesis.Furthermore,comparative analysis of flavonoid-related MYB factors involving FhPAP1,FhMYB5,FhMYBF1,and FhMYB21L2 highlighted their roles in regulating PA,anthocyanin,and flavonol biosynthesis,with some exhibiting versatile regulations.Overall,our findings provide insights into the spatio-temporal regulation of flavonoids in flowers and expand our understanding of MYB-mediated transcriptional regulation of specialized metabolites in plants. 展开更多
关键词 cooperative regulation regulatory network molecular insights floral flavonoids biosynthesis proanthocyanidins freesia hybrida red tt type myb regulators freesia hybrida
暂未订购 下载PDF
Genomic insights into the absence of root nodule formation and nitrogen fixation in Zenia insignis 认领 引用
8
作者 Hang Yu Yongbin Lu +4 位作者 Chao Zhang Wenyuan Yang Hongjiang Xie Huiru Liu Haifeng Wang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2025年第6期860-863,共4页
Symbiotic nitrogen fixation in members of the Fabaceae family is highly efficient and beneficial for global agriculture,but not all species in this family form root nodules with rhizobial bacteria.Nodulation mainly oc... Symbiotic nitrogen fixation in members of the Fabaceae family is highly efficient and beneficial for global agriculture,but not all species in this family form root nodules with rhizobial bacteria.Nodulation mainly occurs in plants belonging to the Papilionoideae and Caesalpinioideae subfamilies(Tederso0 et al.,2018;van Velzen et al.,2019).Nodulation mechanisms in Fabaceae are well studied(Yang et al.,2022),and genomic comparisons of nodulating and non-nodulating host species can provide valuable insights into the evolutionary and genetic basis of this key process. 展开更多
关键词 nitrogen fixation genomic insights rhizobial bacterianodulation symbiotic nitrogen fixation root nodule formation Zenia insignis genomic comparisons Fabaceae
暂未订购 下载PDF
Genomic insights into deleterious mutations and their impact on agronomic traits during pear domestication 认领 引用 被引量:2
9
作者 Xiang Zhang Bobo Song +10 位作者 Shuai Du Shiqiang Zhang Yuexing Ren Cheng Xue Shaozhuo Xu Pengfei Zheng Shulin Chen Zhiwen Qiao Jiahao Liu Wei Wei Jun Wu 《Horticulture Research》 SCIE CSCD 2025年第9期76-90,共15页
The pear(Pyrus spp.),a perennial fruit tree,is subjected to genetic alterations over decades or even centuries to adapt to complex climatic and cultivation conditions.Genome-wide studies of deleterious mutations remai... The pear(Pyrus spp.),a perennial fruit tree,is subjected to genetic alterations over decades or even centuries to adapt to complex climatic and cultivation conditions.Genome-wide studies of deleterious mutations remain limited in perennial fruit trees,particularly regarding the effects of domestication on deleterious mutations.In this study,232 pear accessions were resequenced,and 9909773 single-nucleotide polymorphisms(SNPs),and 139335 deleterious mutation sites,were identified genome wide.A higher proportion of deleterious mutations in coding regions(1.4%)were observed in the pear genome than annual crops.During domestication,a reduction in deleterious mutations in Pyrus pyrifolia/P.bretschneideri was found to be associated with their decreases in selective sweep regions.Conversely,an increase in the number of deleterious mutations in P.communis was observed,which may be related to a higher occurrence within selective sweep regions.In P.ussuriensis,an overall increasing trend in deleterious mutations was identified,which was determined to be unrelated to domestication or gene introgression but instead linked to its relatively high heterozygosity.Differential deleterious mutation genes were identified during the domestication process.Among these,the PyMYC2 gene,associated with stone cell synthesis,was identified through GWAS,overexpression of PyMYC2 in pear callus significantly promoter lignin biosynthesis,PyMYC2 contains three nonsynonymous deleterious mutations that were selected during the domestication of Asian pears.This research provides new insights into developing future breeding strategies aimed at improving agronomic traits and offers a framework for studying deleterious mutation patterns in the domestication of perennial fruit trees. 展开更多
关键词 agronomic traits genomic insights selective sweep regions single nucleotide polymorphisms deleterious mutations pear domestication genetic alterations higher proportio
暂未订购 下载PDF
Autophagy regulation and function in axon regeneration:new insights from Caenorhabditis elegans 认领 引用 被引量:1
10
作者 Su-Hyuk Ko Lizhen Chen 《Neural Regeneration Research》 SCIE CAS CSCD 2025年第12期3519-3520,共2页
Autophagy plays a crucial role in axon regeneration by maintaining cellular homeostasis and promoting the clearance of damaged organelles and proteins,which is essential for the growth and repair of axons.In response ... Autophagy plays a crucial role in axon regeneration by maintaining cellular homeostasis and promoting the clearance of damaged organelles and proteins,which is essential for the growth and repair of axons.In response to axonal injury,autophagy is upregulated to facilitate the removal of cellular debris and support the recycling of essential components needed for regeneration. 展开更多
关键词 homeostasis debris insight
暂未订购 下载PDF
Atomistic insights into dynamic evolution of solid electrolyte interface 认领 引用
11
作者 Yilin Chen Yuxin Fan +4 位作者 Yongqing Gong Chenlong Gao Yunhui Huang Wei Luo Menghao Yang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2025年第12期401-411,I0012,共11页
Lithium-ion batteries are at the forefront of modern energy storage technology.However,the accumulation of by-products such as ethylene and carbon dioxide during charging and discharging cycles reduces battery effecti... Lithium-ion batteries are at the forefront of modern energy storage technology.However,the accumulation of by-products such as ethylene and carbon dioxide during charging and discharging cycles reduces battery effective capacity and threatens large-scale safe performance.With significant advantages over ethylene carbonate(EC)electrolytes,fluorinated electrolytes can more effectively suppress internal gas evolution,thereby improving battery safety and cycling stability.To reveal the mechanism behind gas formation in lithium-ion batteries,our study investigated the transport behavior and interfacial products of fluorinated electrolytes under various operation conditions,including electrode material and electrolyte composition.Innovatively,we applied the reaction network integrator ReacNetGenerator to the analysis of the solid electrolyte interface(SEI)in lithium batteries,providing more molecular fingerprint information from the perspective of specific products.Using reactive molecular dynamics(MD)simulations with the ReaxFF force field and EChemDID,complemented by density functional theory(DFT)calculations,our results demonstrate that fluorinated electrolytes can effectively suppress the decomposition of LiPF6 to produce toxic gases PFs and PF_3.DFT analysis further reveals that highly fluorinated solvents(e.g.,FEMC)enhance the anti-reduction stability of PF6~-through synergistic regulation of molecular orbital energy levels,thermodynamic electron affinity,charge transfer,and electrostatic potential distribution,thereby mitigating LiPF6 decomposition.Additionally,fluorinated electrolytes generate significantly more LiF components than non-fluorinated ones to promote the formation of a stable and durable solid electrolyte interface(SEI).Experimental validations via XPS and GC-MS confirm reduced CO2 generation and LiF-enriched SEI formation,aligning with simulation and DFT data.The findings provide valuable insights for the design of advanced electrolytes aimed at ensuring large-scale,safe energy storage solutions. 展开更多
关键词 Atomistic insights into dynamic evolution of solid electrolyte interface
暂未订购 下载PDF
Re-evaluating drug-coated balloon use in the elderly:a need for comparative and stratified insights 认领 引用
12
作者 Syeda Fadak Zahra Hujjat 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2025年第10期886-886,共1页
Iread with great interest the recent article by Shin,et al.[1]the authors present an important exploration into the use of drug-coated balloon(DCB)in patients aged≥75 years,a demographic increasingly encountered in m... Iread with great interest the recent article by Shin,et al.[1]the authors present an important exploration into the use of drug-coated balloon(DCB)in patients aged≥75 years,a demographic increasingly encountered in modern cardiovascular practice.The authors conducted a retrospective analysis involving 2050 elderly patients(aged≥75 years)undergoing successful percutaneous coronary intervention(PCI). 展开更多
关键词 retrospective analysis elderly percutaneous coronary intervention pci stratified insights comparative analysis percutaneous coronary intervention drug coated balloon
暂未订购 下载PDF
Mechanistic Insights into Electrocatalytic Urea Oxidation Reaction Through in situ Characterizations 认领 引用
13
作者 Suzhen Bai Yi Zeng +3 位作者 Zhengshan Tian Kesheng Cao Xingwu Li Haoqi Wang 《化学进展》 SCIE CAS CSCD 北大核心 2025年第12期1769-1791,共23页
The electrocatalytic urea oxidation reaction(UOR)has emerged as an energy-efficient alternative to the traditional oxygen evolution reaction for hydrogen production,with mechanistic understanding being critical for th... The electrocatalytic urea oxidation reaction(UOR)has emerged as an energy-efficient alternative to the traditional oxygen evolution reaction for hydrogen production,with mechanistic understanding being critical for the rational design of catalysts.This review systematically summarizes recent advances in in situ characterization techniques for elucidating the dynamic reaction mechanisms of UOR.Studies reveal that phase transitions,valence state migration,and electronic structure evolution of catalysts under operational conditions are key factors governing activity and stability.Techniques such as in situ X-ray diffraction,X-ray absorption spectroscopy,Raman spectroscopy,and Fourier-transform infrared spectroscopy enable real-time monitoring of catalyst reconstruction,intermediate evolution,and interfacial adsorption behavior,overcoming the environmental deviations inherent in conventional ex situ characterization.When combined with theoretical calculations,these methods provide direct evidence for identifying active-site configurations,reaction pathways,and rate-determining steps.In addition,special emphasis is placed on multimodal in situ strategies for deciphering synergistic effects in nickel-based catalysts,while current challenges,including non-alkaline systems,real wastewater environments,and multi-metal cooperation mechanisms,are critically discussed.Future research should focus on developing novel in situ approaches for complex systems and establishing a mutually reinforcing framework integrating theoretical prediction and experimental validation,thereby advancing UOR catalyst design from empirical exploration to mechanism-guided optimization. 展开更多
关键词 urea oxidation reaction mechanistic insight in-situ characterizations active sites dynamic evolution
暂未订购 下载PDF
Improved chromosome-level donkey(Equus asinus)genome provides insights into genome and chromosome evolution 认领 引用
14
作者 Ge Yang Mian Gong +5 位作者 Qi-Meng Yang Yi-Dan Li Halima Jafari Chu-Zhao Lei Yu Jiang Rui-Hua Dang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2025年第2期269-272,共4页
The donkey is an important livestock species that can provide milk,meat,and skin and belongs to the family Equus.The first genome of a male donkey was sequenced and de novo assembled using a whole-genome shotgun strat... The donkey is an important livestock species that can provide milk,meat,and skin and belongs to the family Equus.The first genome of a male donkey was sequenced and de novo assembled using a whole-genome shotgun strategy(Huang et al.,2015).Subsequently,the donkey genome showed greater improvement in continuity and chromosome length than a previous assembly(Renaud et al.,2018). 展开更多
关键词 insight belongs
暂未订购 下载PDF
Exploring Challenges in Teaching English Through Literature Curriculum in Myanmar Higher Education:Insights from Stakeholders 认领 引用
15
作者 Mary 《Sino-US English Teaching》 2025年第12期251-262,共12页
The objectives of this qualitative research were:(a)to analyze the challenges faced by English literature teachers in teaching English through literature curriculum in English as a foreign language(EFL)classrooms of M... The objectives of this qualitative research were:(a)to analyze the challenges faced by English literature teachers in teaching English through literature curriculum in English as a foreign language(EFL)classrooms of Myanmar;and(b)to examine the insights from stakeholders towards teaching English through literature curriculum in EFL classrooms of Myanmar.The samples were composed of 27 English literature teachers from specific Arts and Science Universities,six government officials and three local business leaders.They were selected through a purposive sampling method.The research conducted through a semi-structured interview,classroom observation,and focus group discussion.Content analysis and document analysis were used to analyze the data.The findings suggest that challenges can be categorized into three groups:student-related,teacher-related,and external factors.Additionally,the study highlights the importance of students’language proficiency,linguistic,and stylistic complexity of texts,and cultural familiarity in influencing the teaching-learning process.The results contribute to a better understanding of the challenges faced by English literature teachers in Myanmar,offering insights for the improvement of teaching practices in this context. 展开更多
关键词 challenges English literature curriculum Myanmar Higher Education insights from stakeholders
暂未订购 下载PDF
A Preliminary Study of Greenhouse Gas Emissions From Transportation in Tainan City Using Google Environmental Insights Explorer(EIE) 认领 引用
16
作者 Chen Yen-Chieh Sie Cheng-Syue Chung Ta Huan 《Management Studies》 2025年第3期97-104,共8页
In recent years,with the increasing attention to issues related to carbon emissions,such as carbon tariffs and government netzero carbon emission policies,carbon emissions have become an important indicator that is be... In recent years,with the increasing attention to issues related to carbon emissions,such as carbon tariffs and government netzero carbon emission policies,carbon emissions have become an important indicator that is being prioritized by governments worldwide.The Google Environmental Insights Explorer(EIE)tool has been developed to facilitate the collection and integration of data in this context.This study focuses on Tainan City and utilizes EIE to analyze greenhouse gas emissions from transportation.By using EIE,the study obtains data on greenhouse gas emissions from transportation activities in Tainan City.EIE utilizes data collected by Google and simulation functions to estimate data based on actual measurements of transportation activities.This tool saves time and resources by eliminating the need for on-site investigations while providing data that closely represent the real emissions from transportation activities in urban areas.Transportation vehicles contribute to greenhouse gas emissions in two ways:through direct combustion of fossil fuels and through the consumption of electricity in electric vehicles(EVs).The level of greenhouse gas emissions in a city’s transportation industry depends on factors such as transportation modes,fuel types,fleet age and energy efficiency,total distance traveled,and annual mileage.EIE estimates the greenhouse gas emissions from Tainan City’s transportation industry in 2022 to be 3,320,000 metric tons,including emissions from buses,motorcycles,cars,walking,railways,bicycles,and other modes of transportation. 展开更多
关键词 Google Environmental Insights Explorer transportation industry greenhouse gas emissions
暂未订购 下载PDF
Making bridges between preclinical and clinical insights into age-related cognitive decline 认领 引用 被引量:2
17
作者 David VC Brito Clévio Nóbrega 《Neural Regeneration Research》 SCIE CAS CSCD 2025年第8期2321-2322,共2页
With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether th... With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether they are physiological or pathological. 展开更多
关键词 bridges becoming insight
暂未订购 下载PDF
Emerging insights into the function of very long chain fatty acids at cerebellar synapses 认领 引用
18
作者 Martin-Paul Agbaga Mohiuddin Ahmad 《Neural Regeneration Research》 SCIE CAS CSCD 2025年第6期1709-1710,共2页
Very long chain-saturated and-polyunsaturated fatty acids(VLC-SFA and VLC-PUFA, respectively) are a functionally important class of fatty acids containing 28 carbons or more in their acyl chain. They are synthesized b... Very long chain-saturated and-polyunsaturated fatty acids(VLC-SFA and VLC-PUFA, respectively) are a functionally important class of fatty acids containing 28 carbons or more in their acyl chain. They are synthesized by the elongation of very long fatty acids-4(ELOVL4) enzyme, expressed mainly in the brain, retina, skin, testes, and meibomian gland, where these fatty acids are found(Agbaga et al., 2008). Further, these organs exhibit tissuespecific VLC-PUFA and VLC-SFA biosynthesis and incorporation into complex lipids for specific functions. In the brain, skin, and Meibomian glands, the ELOVL4 mainly makes VLC-SFA, which are incorporated into complex sphingolipids. In the retina, the ELOVL4 makes VLC-PUFA that are incorporated into phosphatidylcholine, that are critical for visual function, while in testes and sperm, the VLC-PUFA are incorporated into sphingolipids that are critical for fertility(Yeboah et al., 2021). 展开更多
关键词 functions function insight
暂未订购 下载PDF
Genome-wide association analysis provides molecular insights into natural variation in watermelon seed size 认领 引用 被引量:5
19
作者 Chengsheng Gong Shengjie Zhao +6 位作者 Dongdong Yang Xuqiang Lu Muhammad Anees Nan He Hongju Zhu Yong Zhao Wenge Liu 《Horticulture Research》 SCIE CSCD 2022年第1期962-972,共11页
Watermelons used for seed consumption tend to have larger seeds,whereas watermelons used for flesh consumption often require relatively small seeds.Therefore,watermelon seed size has received extensive attention from ... Watermelons used for seed consumption tend to have larger seeds,whereas watermelons used for flesh consumption often require relatively small seeds.Therefore,watermelon seed size has received extensive attention from consumers and breeders.However,the natural variation and genetic mechanism of watermelon seed size remain unclear.In the present study,100-seed weight,seed hilum length,seed length,seed width,and seed thickness were examined in 197 watermelon accessions.Furthermore,association analysis was performed between seed size traits and high-quality SNP data.The results revealed that there were strong correlations among the five seed traits,and seed enlargement was an important feature during watermelon seed size domestication.The seedconsumed biological species Citrullus mucosospermus and the edible seed watermelon Citrullus lanatus had significantly larger seeds than the other species.Eleven non-repeating significant SNPs above the threshold line were obtained from GWAS analysis.Four SNPs on chromosome 5 were considered to be closely associated with seed size traits(S5:32250307,S5:32250454,S5:32256177,and S5:32260870)and could be used as potential molecular markers for the breeding of watermelon cultivars with a target seed size.In addition,based on gene annotation information and previous reports,five genes near the four significant SNPsmay regulate seed size.qRT-PCR analysis showed that two genes that may be involved in abscisic acid metabolism,Cla97C05G104360 and Cla97C05G104380,may play an important role in regulating watermelon seed size.Our findings provide molecular insights into natural variation in watermelon seed size and valuable information for molecular marker-assisted breeding. 展开更多
关键词 natural variation genetic mechanism molecular insights molecular markers seed traits SNP genetic mechanism watermelon seed size domestication
暂未订购 下载PDF
Sodium iodate induced retinal degeneration: new insights from an old model 认领 引用 被引量:9
20
作者 Ram Kannan David R.Hinton 《Neural Regeneration Research》 SCIE CAS CSCD 2014年第23期2044-2045,共2页
Studies on the selective retinal degeneration induced by sodium iodate (NaIO3) date back to 1941; Sorsby (1941) described the effect of intravenously injected NaIO3 solution on the rabbit retina. Since then, NaIO3... Studies on the selective retinal degeneration induced by sodium iodate (NaIO3) date back to 1941; Sorsby (1941) described the effect of intravenously injected NaIO3 solution on the rabbit retina. Since then, NaIO3-induced retinal degeneration has been described in different mammalian species including sheep, rabbit, rat and mouse with varying doses and routes of administration. At the present time, 展开更多
关键词 IO new insights from an old model RPE
暂未订购 下载PDF
上一页 1 2 36 下一页 到第
在线咨询 使用帮助 返回顶部 意见反馈