期刊文献+
任意字段
题名或关键词
题名
关键词
摘要
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息
共找到12,811篇文章
< 1 2 … 250 >
每页显示 20 50 100
已选0条
引用分析
参考文献
引证文献
 统计分析
检索结果
已选文献
显示方式：
The Fully Interactive Martian Dust Cycle Simulations by the GoMars Model 认领 引用 被引量：3
1
作者 Shuai LIU Li DONG +9 位作者 Xiangyu XI Xuan CHENG Juanjuan LIU Ye PU Yiyuan LI Hongbo LIU Mingyu LIU Wei XUE Junji CAO Bin WANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2026年第3期461-476,共16页
The dust cycle is a crucial component of the present-day Martian climate system.This study examines its multitimescale variability using an optimized 50-year simulation with the fully interactive scheme from the Globa... The dust cycle is a crucial component of the present-day Martian climate system.This study examines its multitimescale variability using an optimized 50-year simulation with the fully interactive scheme from the Global Open Planetary Atmospheric Model for Mars(GoMars),a newly developed Mars General Circulation Model(MGCM).GoMars is able to reproduce the diurnal,seasonal,and interannual characteristics of the dust cycle in several key aspects,with high repeatability in diurnal and seasonal variations during non-global dust storm(non-GDS)years.The model’s“climatology”(non-GDS years ensemble mean)captures the seasonal pattern and magnitude of the vertical–meridional dust distribution,validated against Mars Climate Database and Mars Climate Sounder observations.In the absence of direct observations,the GoMars-simulated near-surface wind stress lifting flux is evaluated through comparisons with other MGCMs(e.g.,MarsWRF),revealing consistent seasonal and spatial patterns.As for the diurnal cycle,the peak dust devil lifting flux occurs at 1200–1300 local time,matching the Mars Pathfinder measurements.The model also successfully captures the intense dust devil activity in Amazonis,a region identified as a major dust devil hotspot based on observational data.In GDS years,GoMars effectively reproduces spontaneous GDSs,capturing their observed onset times,locations,and dust transport patterns as exhibited in specific Martian years.The model also simulates significant interannual variability,with irregular GDS intervals along with reasonable dust–atmosphere interactions. 展开更多
关键词 GoMars dust cycle fully interactive dust interannual variability
暂未订购 下载PDF
Molecular kinetic modelling of confined fluid transport-a mesoscopic approach 认领 引用 被引量：1
2
作者 Baochao Shan Shaokang Li +3 位作者 Guihua Tang Manuel Torrilhon Yonghao Zhang Zhaoli Guo 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第2期83-104,共22页
Accurate modelling of confined fluid transport requires addressing the fluid-fluid and fluid-surface interactions across multiple scales,particularly when molecular sizes are comparable to the fluid mean free path and... Accurate modelling of confined fluid transport requires addressing the fluid-fluid and fluid-surface interactions across multiple scales,particularly when molecular sizes are comparable to the fluid mean free path and the confinement dimension.Advances in nanotechnology have sparked tremendous interest in the combined effects of non-equilibrium,real-fluid properties,and confinement on multiscale flows,where the Knudsen number or confinement dimension can vary widely.This review discusses molecular kinetic modelling approaches for:(1)fluid density ranging from dilute,where non-equilibrium effects dominate,to dense,where real fluid effects become critical;(2)flow domains ranging from macroscale to nanoscale,necessitating confinement-specific treatments;(3)fluid-surface interactions at various densities and confinements.The pronounced non-equilibrium and confinement effects introduce both intrinsic and apparent non-hydrodynamic effects,which require careful consideration in developing a molecular kinetic model. 展开更多
关键词 Multiscale simulation Non-equilibrium flow Fluid-surface interaction Confinement Slip flow
暂未订购 下载PDF
Studies and analysis of drug-target interactions by affinity chromatography and related techniques:A review 认领 引用 被引量：1
3
作者 David S.Hage Sadia Sharmeen +5 位作者 B.K.Sajeeb Harshana Olupathage Md Masudur Rahman Isaac Kyei Samiul Alim Nigar Sultana Pinky 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2026年第2期330-346,共17页
The characterization of drug-target interactions is a key component of drug discovery,testing,and development.Affinity chromatography is one approach that can be used for this type of analysis.For instance,this may be... The characterization of drug-target interactions is a key component of drug discovery,testing,and development.Affinity chromatography is one approach that can be used for this type of analysis.For instance,this may be done by using an immobilized target as a stationary phase and a drug as the applied solute.This review will discuss the various ways in which affinity chromatographic methods have been used to examine drug-target interactions,with an emphasis on high-performance methods.The general principles of this approach and factors to consider in its use for drug-target interaction analysis will first be examined.Methods based on zonal elution or frontal analysis for binding and competition studies will then be discussed.Various techniques for kinetic studies will next be considered,along with approaches that employ secondary binding agents and hybrid techniques.In each case,the general principles and theory of an approach will be given along with examples of its use in drug-target interaction studies.Advantages or limitations of each approach will be provided as well.This information should make it possible in the future to extend these techniques to other drug-target systems of interest in biomedical research and drug testing or development. 展开更多
关键词 Affinity chromatography High-performance affinity chromatography Drug-target interactions Drug-protein binding Kinetic analysis Biointeraction analysis
暂未订购 下载PDF
Support engineering of single-atom electrocatalysis:Mechanism analysis and application expansion 认领 引用 被引量：1
4
作者 Mingying Chen Junjie Ma +3 位作者 Xiyong Chen Qian Liu Yanhong Feng Xijun Liu 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第4期117-127,共11页
Electrocatalysis stands as a cornerstone in the pursuit of clean energy conversion and environmental sustainability,with single-atom catalysts(SACs)emerging as a transformative paradigm for enhancing electrocatalytic ... Electrocatalysis stands as a cornerstone in the pursuit of clean energy conversion and environmental sustainability,with single-atom catalysts(SACs)emerging as a transformative paradigm for enhancing electrocatalytic efficiency.In the architectural design of SACs,supports transcend conventional roles as mere supports,actively governing catalytic performance via robust metal-support interactions(SMSI).This review comprehensively analyses the key role of support engineering in modulating SACs performance.The study begins with a systematic assessment of currently popular SACs synthesis strategies,critically comparing their advantages and limitations.Through a hierarchical analysis,it reveals the impact of various support materials,such as carbon-based materials,metal oxides,MXenes,and metal-organic frameworks(MOFs),on the catalytic performance of SACs,with emphasis on their structural characteristics,electronic properties,and interaction mechanisms with active sites.The review further explores applications in energy conversion/storage and environmental remediation,while addressing current challenges and proposing future research directions for SACs development.By providing actionable insights,this work aims to guide the design of next-generation SACs and advance sustainable electrocatalysis. 展开更多
关键词 Electrocatalysis Single-atom catalysts Strong metal-support interactions Support engineering
暂未订购 下载PDF
Novel Ketone-Based IPDA Phase Change Absorbents for Highly Efficient Wide-Concentration-Range CO2 Capture and Low-Energy Regeneration 认领 引用 被引量：1
5
作者 Qingrui Zeng Ziang Jia +3 位作者 Yingyang Song Yiwen Fan Xu Liu Jinping Cheng 《Engineering》 SCIE EI CSCD 2026年第3期221-236,共16页
Carbon dioxide capture and storage (ccs) is an important technological path for realizing "carbon neutrality," where carbon capture is one of the three key CcS technologies. At present, mature carbon capture... Carbon dioxide capture and storage (ccs) is an important technological path for realizing "carbon neutrality," where carbon capture is one of the three key CcS technologies. At present, mature carbon capture technologies still have technical shortcomings and difficulties, such as low capture efficiency and high energy consumption, which limit their large-scale popularization and application. In this study, a solid liquid phase change absorbent (PCA) system with isophorone diamine (IPDA) as the only carbon dioxide (CO2) capture carrier and ketone-based organic molecules as the phase change medium was developed.The solid-liquid PCA system has a wide range of applicability,with highly efficient CO2 capture (1.11 mol·mol-1) at concentrations ranging from typical values in air to those in coal-fired industrial emissions (400 to 150000 ppm) and low-energy consumption regeneration, as revealed by a two-phase integrated engineering model. The CO2 absorption product IPDA(NHCOO-)2 was characterized by materials science analysis, molecular dynamics (MD) calculations, and quantum chemistry. The results indicate that in noncyclic ketone-based phase-change media, the hydrogen bonding in IPDA(NHCOO-)2 is modulated by noncovalent bond interaction (NCI) forces to form a small-scale hydrogen-bonding network. These properties ensure that the product can be easily regenerated by low-temperature thermal treatment (333 K,60℃), and characterization and calculations revealed a reaction mechanism different from that of the aqueous system. The technoeconomic evaluation (TEA) results show that this type of ketone-based PCA has an obvious low-cost advantage over traditional carbon capture technologies. This study provides a new perspective on the application and practical feasibility of PCAs for direct air capture of carbon dioxide. 展开更多
关键词 CO2capture Phase change absorbents IPDA Molecular dynamics Noncovalent interactions
暂未订购 下载PDF
Different poisoning behaviors of impurity gases on AB2-type Ti-based hydrogen storage alloys and their mechanisms 认领 引用 被引量：1
6
作者 Yongpeng Chen Panpan Zhou +7 位作者 Jiapeng Bi Liuhui Zhu Lingchao Zhang Chengguo Yan Yuxiao Jia Xuezhang Xiao Xinhua Wang Lixin Chen 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第3期350-361,共12页
AB2-type Ti-based hydrogen storage alloys(HSAs)are promising for industrial hydrogen feeding systems due to their moderate operating conditions and high hydrogen storage capacity.However,their practical application... AB2-type Ti-based hydrogen storage alloys(HSAs)are promising for industrial hydrogen feeding systems due to their moderate operating conditions and high hydrogen storage capacity.However,their practical application is hindered by unavoidable impurity gases in hydrogen feedstocks,which significantly impair the performance of HSAs.Furthermore,the absence of clear evaluation criteria for poisoning behaviors and mechanisms hinders efforts to develop effective mitigation strategies.To address this gap,we used calculated surface interaction energy changes(ΔE)and experimental investigations to classify and rank the poisoning potential of impurity gases on a C14 Laves-phase Ti0.86Zr0.15Mn1.5Cr0.07(VFe)0.43 alloy.Impurity gases were classified into two types of weak-adsorption and strong-adsorption impurity gases by comparing theirΔE with that of H2(ΔE_(H2)=-1.6001 eV).AsΔE>ΔE_(H2) ,weak-adsorption impurity gases(Ar,He,CH4,and N2)induce poisoning by forming enriched blocking layers that impede H2 diffusion.This blocking effect can be alleviated under gas flow conditions.AsΔE<ΔE_(H2),strong adsorption gases are further divided into two types based on their reactivity with the alloy.Non-reactive strong-adsorption impurity gases(CO and CO2 )preferentially occupy surface active sites,blocking H2 adsorption and dissociation.In contrast,reactive strong-adsorption impurity gases(such as O2)form dense passivation layers that completely prevent hydrogen ingress.Accordingly,surface modification offers an effective approach to mitigate gas-induced poisoning by altering the interaction mechanism.This study establishes the parameter-based criteria for classifying impurity gas poisoning mechanisms in AB2-type Ti-based HSAs.It provides fundamental insights for guiding the design of poisoning-resistant materials and the development of mitigation strategies. 展开更多
关键词 Ti-based hydrogen storage alloys Impurity gas Surface interaction energy change Poisoning mechanisms
暂未订购 下载PDF
Improvements in Fracture Parameter Evaluation of Mixed-Mode Problems Using Modified Peridynamics 认领 引用 被引量：1
7
作者 Hanlin Wang Lei Ju +5 位作者 Yanzhuo Xue Lihao Yuan Qing Wang Duanfeng Han Satoyuki Tanaka Erkan Oterkus 《哈尔滨工程大学学报（英文版）》 CSCD 2026年第3期684-692,共9页
Peridynamics(PD),which underpins many meshfree methods,has found widespread applications in fracture mechanics.However,its accuracy in simulating shear behavior remains limited,particularly for mixed-mode fracture pro... Peridynamics(PD),which underpins many meshfree methods,has found widespread applications in fracture mechanics.However,its accuracy in simulating shear behavior remains limited,particularly for mixed-mode fracture problems.To address this,we propose a modified formulation of ordinary state-based PD(OSPD)that incorporates bond rotation behavior,including shear deformation and rigid body rotation(RBR).Using the peridynamic differential operator,the stress-free RBR component is identified and removed from the total displacement.The enhanced formulation is validated through classical benchmark problems,with stress intensity factors evaluated using the interaction integral method.Numerical results demonstrate excellent agreement with reference solutions from the literature and the original OSPD model,confirming the improved accuracy of the modified OSPD model.Notably,the modified model exhibits superior performance in simulating shear deformation,establishing its reliability in mixed-mode fracture analysis. 展开更多
关键词 Fracture analysis Peridynamics Stress intensity factors Interaction integral Shear deformation
暂未订购 下载PDF
Breaking the boundaries of affinity selection-mass spectrometry:From ligand screening to target-ligand interaction insights 认领 引用 被引量：1
8
作者 Pamella Christina Ortega de Oliveira Bruno Sergio do Amaral +2 位作者 Carmen Lucia Cardoso Quezia Bezerra Cass Marcela Cristina De Moraes 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2026年第2期347-358,共12页
Affinity selection mass spectrometry(AS-MS)has emerged as a powerful label-free technique for identifying and characterizing ligand-target interactions.This review explores the diverse applications of AS-MS in drug di... Affinity selection mass spectrometry(AS-MS)has emerged as a powerful label-free technique for identifying and characterizing ligand-target interactions.This review explores the diverse applications of AS-MS in drug discovery,including its role in selective screening,binding site characterization,and quantitative affinity determination.We discuss the use of AS-MS for determining equilibrium dissociation constants(KD)and competitive binding parameters(affinity competition experiment 50%(ACE50)),highlighting its ability to rank ligand affinities efficiently.The review also examines AS-MS applications in fragment-based drug discovery(FBDD),screening for molecular glues,and investigating interactions with membrane proteins.Moreover,we address key technical challenges,including competitive binding effects,protein stability,and ligand dissociation kinetics,along with recent advancements in automation and artificial intelligence(AI)integration.Rather than providing a comprehensive literature review,this work aims to broaden the applicability of AS-MS assays and encourage researchers to explore its use in underutilized contexts.By providing rapid and high-sensitivity affinity measurements,AS-MS continues to expand its role in drug discovery and structural biology,complementing conventional biophysical techniques. 展开更多
关键词 Affinity selection mass spectrometry Competition assays Drug discovery Fragment screening KD determination Ligand-target interactions Molecular glues
暂未订购 下载PDF
A survey of panel aeroelasticity in shock-dominated flow:Perspectives from fluid-structure interactions and shock wave-boundary layer interactions 认领 引用 被引量：1
9
作者 Aiming SHI Yiwen HE 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2026年第1期210-229,共20页
As a multidisciplinary phenomenon,panel aeroelasticity in shock-dominated flow is featured by two primary interactions:Fluid-Structure Interactions(FSIs)and Shock-Boundary Layer Interactions(SBLIs).The former raises s... As a multidisciplinary phenomenon,panel aeroelasticity in shock-dominated flow is featured by two primary interactions:Fluid-Structure Interactions(FSIs)and Shock-Boundary Layer Interactions(SBLIs).The former raises structural concerns,and the latter is of aerodynamic interest.Thus,panel aeroelasticity in shock-dominated flow represents a vital topic for the development and optimization of supersonic vehicles and propulsion systems.This review systematically summarizes recent advances in the methodologies applied to capture structural and fluid dynamics,including theoretical models,numerical simulations,and wind tunnel experiments.The application of data-driven modal decomposition,an advanced technique to extract physically crucial features,on the topic is introduced.From the perspective of FSIs,the distinctive aeroelastic behaviors in shock-dominated flow,including hysteresis phenomena and nonlinear responses,are highlighted.From the perspective of SBLIs,the modifications in their spatial and temporal characteristics imposed by the aeroelastic responses are emphasized.Motivated by the interaction between the shock waves and structural response,different strategies have been proposed to implement aeroelastic suppression and shock control,which have the potential to enhance structural safety and aerodynamic performance in the next generation of high-speed flight vehicles. 展开更多
关键词 Aeroelasticity Fluid structure interaction Modal decomposition Shock boundary layer interactions Shock waves
暂未订购 下载PDF
Evaluation of vehicle-track-bridge interacted system for the continuous CRTS-II non-ballast track slab 认领 引用 被引量：17
10
作者 ZHANG Nan ZHOU Shuang +1 位作者 XIA He SUN Lu 《Science China(Technological Sciences)》 SCIE EI CAS 2014年第10期1895-1901,共7页
Considering the CRTS-II track slab,which is commonly used in the Chinese high-speed railway system,a vehicle-track-bridge dynamic analysis method is proposed in which the vehicle subsystem equations are established by... Considering the CRTS-II track slab,which is commonly used in the Chinese high-speed railway system,a vehicle-track-bridge dynamic analysis method is proposed in which the vehicle subsystem equations are established by the rigid body dynamics method,the track subsystem and the bridge subsystem equations are established by the FEM,the wheel-rail contact relation is defined by the corresponding assumption in vertical direction and the Kalker linear creep theory in lateral direction.The in-span spring element is derived to model the track-bridge interaction;the equal-band-width storage is adopted to fit the track structure with multilayer uniform section beam;and the dynamic equilibrium equations are solved by the inter-history iteration method.As a case study,the response of a CRH2 high-speed train transverses a simply-supported bridge with successive 31.5m double bound pre-stress beams is simulated.The result shows that using the vehicle-track-bridge interaction model instead of the vehicle-bridge interaction model helps predict the rotation angle at beam ends and choose an economic beam vertical stiffness. 展开更多
关键词 vehicle-track-bridge interacted system CRTS-II track slab in-span spring element equal-band-width storage
暂未订购 下载PDF
A Review on Circumferential Crack Method Used for Simulating Ice-Structure Interaction 认领 引用 被引量：3
11
作者 ZHOU Li 《China Ocean Engineering》 SCIE EI CSCD 2026年第1期1-14,共14页
Structure-ice interaction problems have attracted increasing attention,yet accurately predicting the loads exerted by sea ice on ship hulls remains a significant challenge.Over the past few decades,various numerical m... Structure-ice interaction problems have attracted increasing attention,yet accurately predicting the loads exerted by sea ice on ship hulls remains a significant challenge.Over the past few decades,various numerical methods have been employed to simulate ice resistance on ships and evaluate their manoeuvrability during ice-structure interaction.Among these approaches,the circumferential crack method has demonstrated both high efficiency and accuracy.This paper provides a detailed introduction to the fundamental theory of this method,including the numerical modeling of different failure modes and the dynamic ice motion responses.Furthermore,it reviews existing studies on predicting ice resistance and assessing the manoeuvrability of icebreakers navigating through ice-covered regions using the circumferential crack method.Several recommendations for future research in this field are also presented. 展开更多
关键词 ice forces circumferential crack method ice resistance ice-structure interaction ice failure modes polar ship
暂未订购 下载PDF
Human‑robot interaction design with augmented reality in construction:A systematic review of frameworks,applications,and future directions 认领 引用
12
作者 Tan TAN Xin LIU +2 位作者 Alexander N.WALZER Ming Shan NG Daniel M.HALL 《ENGINEERING Management》 CSCD 2026年第1期85-104,共20页
Research in human‑robot Interaction(HRI)has increasingly demonstrated how Augmented Reality(AR)enables better interactions between humans and robots.However,the design of HRI remains less understood.Through a systemat... Research in human‑robot Interaction(HRI)has increasingly demonstrated how Augmented Reality(AR)enables better interactions between humans and robots.However,the design of HRI remains less understood.Through a systematic literature review of 53 related papers,this research provides an overview of the emerging applications and trends for AR and identifies three types of AR interfaces as follows:1)remote modular interface,2)proximal modular interface,and 3)proximal integral interface.The review indicates potential future directions of construction‑oriented and human‑centric interaction design studies,leading to four pairs of subsystems,which are frequently modularised or integrated,and three conceptual frameworks for HRI interfaces are proposed.Moreover,this research contributes to the theoretical exploration of interaction design.Future applications can adapt to various tasks by using the proposed three conceptual frameworks for interfaces,as well as combining the four proposed subsystem pairs to suit specific task requirements in the construction sector. 展开更多
关键词 augmented reality human‑robot interaction interaction design human‑computer interaction literature review
暂未订购 下载PDF
Host-guest interaction mediated low-shrinkage photosensitive positioning adhesive 认领 引用
13
作者 Zhao Liu Junjian Xie +3 位作者 Xiaoming Ren Muhammad Tahir Shixin Fa Qiuyu Zhang 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第2期501-504,共4页
As a common electronic adhesive,ultraviolet(UV)curing polyurethane acrylate adhesive has both flexibility and wear resistance of polyurethane,excellent weather resistance and optical properties of acrylate.Despite the... As a common electronic adhesive,ultraviolet(UV)curing polyurethane acrylate adhesive has both flexibility and wear resistance of polyurethane,excellent weather resistance and optical properties of acrylate.Despite the extensive applications,it is still difficult to solve the problems caused by the shrinkage of adhesive.Here,a new type of photosensitive adhesive for bonding electronic components based on supramolecular interaction was designed and synthesized.The supramolecular interaction of cyclodextrin and adamantane moieties introduced into the adhesive polymer entitles the viscosity of the adhesive to rise rapidly during use,thereby preventing adhesive loss and dislocation of electronic components.UV light could further cure the adhesive and position the electronic components.The adhesive shrunk<2%when cured by UV light,so it can be used for electronic packaging and high-resolution,defect-free lithography. 展开更多
关键词 Adhesive Host-guest interaction UV-curing Low-shrinkage Lithography
暂未订购 下载PDF
Integrated multi-omics analysis unveils metabolites-mediated microbial interactions:dynamic regulation and metabolic division of A.flavus SU-16 and S.cerevisiae HJ during co-fermentation 认领 引用
14
作者 Shuangping Liu Mingliang Li +5 位作者 Hailong Sun Zhuoyue Zheng Yuezheng Xu Xiao Han Zhilei Zhou Jian Mao 《Food Science and Human Wellness》 SCIE CAS CSCD 2026年第4期1757-1773,共17页
This study aimed to gain insight into the interaction and metabolic mechanism between Aspergillus flavus U-16 and Saccharomyces cerevisiae HJ during co-fermentation.Despite the suppressed transcriptional activity of S... This study aimed to gain insight into the interaction and metabolic mechanism between Aspergillus flavus U-16 and Saccharomyces cerevisiae HJ during co-fermentation.Despite the suppressed transcriptional activity of SU-16,its metabolites exerted a pivotal regulatory influence.The metabolites produced by SU-16 significantly increased the ethanol content to 17.0%.They also significantly increased the contents of crucial flavor substances,including amino acids(at least 5 times)and esters(up to 1100 mg/L).SU-16 produced 130 metabolites that may affect flavor compounds,while HJ mainly controlled the synthesis of 161 compounds.Metabolites of SU-16 with different molecular weights were observed to exert differential regulatory effects on the fermentation process and the metabolic pathway of HJ.The small molecule metabolites of SU-16 promoted the growth of HJ significantly.In contrast,its macromolecular metabolites were found to mainly affect the expression of genes related to carbohydrate and amino acid metabolism in the HJ genome. 展开更多
关键词 Co-fermentation Metabolites Interaction Dual RNA-seq Transcriptomic Metabolomics
暂未订购 下载PDF
Competitive mechanism of microplastic addition for the adsorption of arsenic from an aqueous solution by magnetic biochar-supported layered double hydroxide 认领 引用
15
作者 Zihan Wang Peng Lyu +4 位作者 Lianfang Li Jinli Huang Jing Ye Feng Li Xue Zhou 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第3期832-846,共15页
This study explores the competitive mechanisms of different types of microplastics(MPs)on pentavalent arsenic(As(Ⅴ))adsorption by magnetic biochar-supported layered double hydroxide composite(MBC@LDH).The effects of ... This study explores the competitive mechanisms of different types of microplastics(MPs)on pentavalent arsenic(As(Ⅴ))adsorption by magnetic biochar-supported layered double hydroxide composite(MBC@LDH).The effects of the solution pH,ionic strength,temperature,material dosage,and MP concentration on As(Ⅴ)adsorption were investigated in co-existing MPs and MBC@LDH systems.Results revealed MPs competitively occupied As(Ⅴ)adsorption sites on MBC@LDH,with varying inhibition efficiencies:polyvinyl chloride(PVC)provided 45.44%of the competitive adsorption,representing a significant reduction in adsorption affinity especially in acidic environments and higher ionic strength.The reduced percentage of adsorption capacity of MBC@LDH for As(Ⅴ)induced by polystyrene(PS)was 35.55%,and that for polyethylene(PE)was also just between PVC and PS,especially in acidic environments and higher ionic strength.Further exploration manifested that the presence of MPs decreased the crystallinity of the CaMgAl LDH in MBC@LDH,which disrupted the surface complexation and hydrogen bonding between MBC-LDH and As.In addition,the strengths of the As–O bonds in MBC@LDH were more significantly reduced by PVC with its entering into the binary system rather than PS and PE,which was ascribable to the strong negative charge and hydrophobic separation properties of PVC.Interestingly,PVC promoted the conversion of As(Ⅴ)to As(Ⅲ)on MBC@LDH but not when PE and PS were added,which might be related to the surface chemical bonding and polarity of the different MPs.This study provides a theoretical reference for MPs'competitive adsorption mechanisms of As on porous materials in aqueous environments. 展开更多
关键词 Modified biochar Microplastics Arsenic Competitive adsorption Interaction mechanism
暂未订购 下载PDF
“Dual sweet”supramolecular glycosyl-nanoproteins based on carbohydrate-protein interaction for targeted drug delivery in vivo 认领 引用
16
作者 Kun Shang Yinghua Lv +8 位作者 Yibo Yang Senyu Yang Zelong Chen Ke Yang Cong Li Shuang Chao Yuchao Lu Yuxin Pei Zhichao Pei 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第7期371-379,共9页
Biomolecular self-assembly systems form the cornerstone of biological structures,in which the interactions between carbohydrates and proteins play a crucial role in many life processes.This has driven the development ... Biomolecular self-assembly systems form the cornerstone of biological structures,in which the interactions between carbohydrates and proteins play a crucial role in many life processes.This has driven the development of biomimetic carbohydrate-protein supramolecular assemblies(BCPSAs),which show great potential in biomedical research.We successfully constructed a novel supramolecular hybrid nanocarrier with pH responsiveness and targeting capabilities based on specific interactions between carbohydrates and proteins.This system self-assembles into nanoparticles CA@MP5 in water through the specific binding of mannose clusters on glycosylated pillar[5]arene MP5 with lectin Con A.Additionally,through a host-guest assembly strategy with the synthesized β-D-galactopyranosyl pyridine derivative G,it complexes within the MP5 cavity to form a"double-sweet"supramolecular glyco-nanoprotein(CA@MP5⊃G).This system shows high affinity for the asialoglycoprotein receptor(ASGPR)on HepG2 liver cancer cells.In vitro,the doxorubicin(DOX)-loaded micelles(DCA@MP5⊃G)release drug effectively in acidic environments and significantly inhibit HepG2 cell growth,with reduced toxicity toward normal cells.In vivo,the nanocarrier targets tumors effectively,reducing systemic toxicity and inhibiting tumor growth.This study offers a novel construction strategy for drug delivery systems based on carbohydrate-protein interactions in anti-tumor applications,which is significant for enhancing therapeutic efficacy. 展开更多
关键词 Carbohydrate-protein interactions Glycosyl-nanoproteins Supramolecular self-assembly Drug-targeted delivery Chemotherapy
暂未订购 下载PDF
Gene-Environment Interaction of Rims1 and Adolescent Social Isolation on Schizophrenia-Like Behaviors in Mice 认领 引用
17
作者 Lian-Hong Lin Wei-Min Li +6 位作者 Qian-Yun Wu Shuang-Yan Li Xu-Xuan Ma Yuan Xu Si-Fu Deng Bin Zhang Ji-Hong Liu 《Neuroscience Bulletin》 SCIE CAS CSCD 2026年第5期1021-1037,共17页
Schizophrenia(SCZ)is a severe mental illness influenced by gene-environment interactions(GEI).However,little is known about how GEI mediates SCZ.The present study aimed to examine the underlying mechanism of SCZ media... Schizophrenia(SCZ)is a severe mental illness influenced by gene-environment interactions(GEI).However,little is known about how GEI mediates SCZ.The present study aimed to examine the underlying mechanism of SCZ mediated by GEI.We found that a single environmental factor(two-week adolescent social isolation)or genetic factor(the heterozygous Rims1 knockout mice)did not induce SCZ-like behaviors.Interestingly,two-week adolescent social isolation successfully caused SCZ-like behaviors in heterozygous Rims1 knockout mice,which can be rescued by anti-SCZ drugs.RNA-seq analysis further revealed that synaptic vesicle-related biological processes and target genes were enriched in the hippocampus of GEI animal model mice,which was accompanied by disturbed excitatory synaptic neurotransmission.Finally,the Nrg1 gene was decreased in our RNA-seq analysis,and supplementation of Nrg1 ameliorated SCZ-like behaviors in heterozygous Rims1 socially isolated mice.Our findings establish a novel GEI animal model and offer a potential therapeutic target in the treatment of SCZ. 展开更多
关键词 Schizophrenia Gene-environment interactions Animal model RNA-seq Nrg1
暂未订购 下载PDF
An Asymmetric Sandwich-Structured Hydrogel Enables High-Output Stable Moist-Electric Generation and Self-Powered Sensing 认领 引用
18
作者 Peng Chen Bo He +5 位作者 Huan-Huan Wei Bing-Yan Wang Jia-Wei Yang Xiao-Fei Niu Hai-Feng Xu Gang He 《Rare Metals》 SCIE EI CAS CSCD 2026年第4期950-960,共11页
Moisture-enabled electricity generation technology offers a new paradigm for sustainable energy harvesting,but its practical applications are still limited by issues such as low output power and insufficient long-term... Moisture-enabled electricity generation technology offers a new paradigm for sustainable energy harvesting,but its practical applications are still limited by issues such as low output power and insufficient long-term stability.In this paper,an asymmetric sandwich-structured hydrogel moist-electric generator(SSHMEG)with an ion concentration gradient is designed and constructed.Through dynamic exchange with moisture in ambient humidity,a stable ion diffusion direction is established inside the device,thereby achieving durable and efficient moisture-enabled electricity generation performance.The SSHMEG achieves an open-circuit voltage as high as 1.15 V and a short-circuit current density of 2350μA cm-2 at 90%relative humidity(RH),along with excellent long-term stability(maintaining>1.05 V continuously for 20 days).Featuring high integrability to meet the output requirements of electronic devices,the SSHMEG is highly sensitive to humidity and internal resistance changes(e.g.,respiration and stretching),enabling its application as a self-powered respiration/strain sensor.Combined with deep learning,the strain sensor based on SSHMEG realizes gesture recognition with 100%accuracy.Through the collaborative innovation of the material-structure mechanism,this work paves a new path for the next-generation high-performance,multifunctional,and self-powered MEG systems. 展开更多
关键词 energy human-computer interaction moist-electric generators sandwich-structured hydrogel wearable sensors
暂未订购 下载PDF
Molecular interactions and dynamics of microplastics in indoor dust with lung-inflammatory receptors:A study in academic settings 认领 引用
19
作者 Aswin Kuttykattil Shiv Basant Kumar +5 位作者 Jey Kumar Pachiyappan Sudharsanavasan Chandrasekar Sudhakaran Raja Rajendran Selvakumar Gowthamarajan Kuppusamy Thava Palanisami 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第3期384-390,共7页
Airborne microplastics(MPs)are prevalent indoors,and due to their low aerodynamic diameter,they can be inhaled,posing potential health risks.Although the toxic effects of airborne MPs have been explored using in vivo ... Airborne microplastics(MPs)are prevalent indoors,and due to their low aerodynamic diameter,they can be inhaled,posing potential health risks.Although the toxic effects of airborne MPs have been explored using in vivo and in vitro models,the interactions between MPs and cellular receptors remain understudied.In this research,dust samples from a confined space within an academic setting were investigated for microplastics(MPs)and their abundance.Further,the most prevalent microplastics were used to study receptor binding and competition interaction studies using the In-Silico method against natural agonists and antagonists of major inflammatory receptors,including the human platelet-activating factor receptor(PAFR),C-X-C motif chemokine receptor 1(CXCR1),β2-adrenergic receptor(β2-AR),and toll-like receptor 2(TLR-2).Results revealed that polyester(PE)was the predominant polymer,accounting for 23.96%of the samples.Analysis indicated that a monomer of PET,Ethylene Terephthalate(ET),exhibited a high binding affinity of-6.5 kcal/mol with the PAFR receptor.Additionally,the molecular dynamics and protein-ligand interaction study,which involves hydrogen bonding,explains the differential binding effect of ET and the control compound with the targeted receptor.The complex was formed between the ET and the receptors ofβ2-AR,CXCR1,and TLR-2,with a maximum of seven and a minimum of one hydrogen bond throughout the simulation.This research lays a foundation for understanding the potential health implications of MPs in confined office spaces,underscoring the need for further in vivo and in vitro examinations. 展开更多
关键词 Indoor dust Airborne Microplastics Polyester-receptor interaction In silico
暂未订购 下载PDF
Dynamic behavior of track(rack)-bridge system under running vehicle and temperature load in rack railway 认领 引用
20
作者 Zhihui Chen Lang Wang +2 位作者 Zhixian Chen Zhaowei Chen Jizhong Yang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2026年第1期526-536,共11页
Significant diurnal temperature variations in mountainous rack railways cause stiffness mismatches between the rack structure and simply supported bridges,leading to critical failures like bolt loosening and rack frac... Significant diurnal temperature variations in mountainous rack railways cause stiffness mismatches between the rack structure and simply supported bridges,leading to critical failures like bolt loosening and rack fractures.This study develops a dynamic model of the vehicle-rack-bridge system based on train-track-bridge interaction theory,integrating gear-rack meshing and wheel-rail contact mechanisms.The model analyzes the dynamic response of bridges with varying spans under combined thermal and dynamic loading.Numerical simulations,conducted using finite element analysis,reveal peak vibration accelerations of 1.3 m/s2for the rack,3.0 m/s2for the rail,1.2 m/s2for the sleeper,and 0.1 m/s2for the bridge,with maximum stresses of 3 MPa in the rack,8 MPa in the rail,and 25 MPa in connecting bolts.The results show significant span-dependent amplification of stress and strain in the rack system under thermo-mechanical loading,exceeding material strength limits at 60-meter spans.An innovative elastic connection method is proposed to mitigate stress concentrations effectively,en-hancing system durability.This study introduces a novel approach to modeling complex thermo-mechanical interactions in rack railway systems,validated through extensive simulations,and provides a practical solution for improving structural resilience,offering theoretical guidance for optimizing rack-bridge system design to ensure operational safety in extreme environmental conditions. 展开更多
关键词 Simply supported bridge Rack railway Bridge-track interaction Temperature loads Dynamic Mechanical
暂未订购 下载PDF
已选0条
引用分析
参考文献
引证文献
 统计分析
检索结果
已选文献
上一页 1 2 … 250 下一页 到第 页
在线咨询 使用帮助 返回顶部 意见反馈