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Assessment of the value of complication risk prediction models following interventional therapy for hepatocellular carcinoma in nursing decision-making 认领 引用
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作者 Hui Wang Hao-Tian Guo +3 位作者 Jing Shen Fei Zhang Yue-Jiao Jiang Zhen-Xing Liu 《World Journal of Gastroenterology》 SCIE CAS 2026年第24期44-53,共10页
BACKGROUND Transcatheter arterial chemoembolization(TACE)is a primary interventional modality for intermediate-to-advanced hepatocellular carcinoma(HCC).However,the high incidence of post-procedural complications sign... BACKGROUND Transcatheter arterial chemoembolization(TACE)is a primary interventional modality for intermediate-to-advanced hepatocellular carcinoma(HCC).However,the high incidence of post-procedural complications significantly compromises patient recovery and prognosis.Currently,clinical nursing assessment lacks a multifaceted risk prediction tool that integrates multiple risk factors.AIM To establish a predictive model for postoperative complications in patients with HCC undergoing TACE.METHODS A retrospective analysis was conducted on 386 patients with HCC who underwent interventional therapy at our hospital from January 2023 to December 2024.Patients were divided into a complication group(n=104)and a control group(n=282)based on postoperative complication occurrence.General clinical data and nursing-related indicators were collected and compared between groups.Multivariate logistic regression analysis was used to identify independent risk factors,construct a risk prediction model,and validate its discriminatory power and calibration by using receiver operating characteristic curve and Hosmer-Lemeshow test.RESULTS The incidence of complications following interventional therapy for HCC in this study was 26.94%.Factors associated with complications included age≥60 years,liver cirrhosis,vascular invasion,procedure duration≥2 hours,TACE sessions>2,Child-Pugh grade B,tumor diameter≥5 cm,nutritional risk(Nutritional Risk Screening 2002≥3),anxiety(Self-Rating Anxiety Scale≥50),depression(Self-Rating Depression Scale≥53),caregiver burden(high Zarit Burden Interview Score),functional independence(low Exercise of Self-Care Agency Scale Score),quality of life(low Quality of Life Instruments for Cancer Patients-General Module Score),and low compliance with early postoperative activity and exercise were all independent risk factors(P<0.05).The predictive model demonstrated a C-index of 0.773,an area under the curve of 0.936,sensitivity of 93.25%,specificity of 84.96%,and good calibration(Hosmer-Lemeshow test,P=0.382).CONCLUSION The TACE postoperative complication prediction model derived during the research combines multidimensional clinical and nursing predictors,which proves a high predictive quality and clinical usefulness.It provides healthcare professionals with a scientifically grounded assessment tool to facilitate risk stratification management and precision nursing. 展开更多
关键词 Hepatocellular carcinoma Interventional therapy Transcatheter arterial chemoembolization Complication risk Risk prediction model Nursing decision-making
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Efficacy Evaluation of Interventional Therapy Combined with Intravenous Thrombolysis for Acute Cerebral Infarction 认领 引用
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作者 QIU Jichao 《外文科技期刊数据库（文摘版）医药卫生》 2026年第2期073-077,共5页
Objective To analyze the clinical efficacy of combined interventional therapy and intravenous thrombolysis in the treatment of acute cerebral infarction, and to explore the application value of this combined regimen b... Objective To analyze the clinical efficacy of combined interventional therapy and intravenous thrombolysis in the treatment of acute cerebral infarction, and to explore the application value of this combined regimen by investigating its underlying mechanisms. Methods A total of 60 patients with acute cerebral infarction admitted to our hospital from January 2024 to December 2025 were selected as study subjects and randomly divided into a combined group and a conventional group (n=30 each) using a random number table. The conventional group received only intravenous thrombolysis, while the combined group received both interventional therapy and intravenous thrombolysis. The treatment efficacy rate, neurological deficit scores, and complication rates were compared between the two groups. Results The combined group demonstrated significantly higher treatment efficacy than the conventional group, with significantly lower neurological deficit scores post-intervention and a markedly reduced complication rate (P<0.05). Conclusion Combined interventional therapy and intravenous thrombolysis significantly improve therapeutic outcomes, enhance neurological function, and reduce complication risks in acute cerebral infarction, with its efficacy advantages closely related to the synergistic mechanisms of the two treatment modalities. 展开更多
关键词 Acute cerebral infarction Interventional therapy Intravenous thrombolysis Efficacy Mechanism of action
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Discussion on Clinical Efficacy of Lenvatinib Combined with Interventional Therapy in the Treatment of Malignant Tumors 认领 引用
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作者 WEI Xiaoying 《外文科技期刊数据库（文摘版）医药卫生》 2026年第7期123-128,共6页
Objective: To systematically analyze the clinical efficacy, survival benefit and safety of lenvatinib combined with interventional therapy in the treatment of malignant tumors, and explore the clinical application val... Objective: To systematically analyze the clinical efficacy, survival benefit and safety of lenvatinib combined with interventional therapy in the treatment of malignant tumors, and explore the clinical application value and optimization potential of this combined regimen. Methods: A total of 186 patients with intermediate and advanced malignant tumors were enrolled and divided into control group (93 cases, simple interventional therapy) and study group (93 cases, lenvatinib combined with interventional therapy). Baseline indicators, short-term tumor efficacy, survival prognosis, tumor marker levels and adverse reaction incidence were compared between the two groups. Statistical analyses including independent sample t-test, chi-square test, Kaplan-Meier survival analysis and Cox risk regression model were applied for data processing. Results: The baseline data of the two groups were balanced and comparable (P>0.05). The study group presented significantly higher objective response rate and disease control rate, lower levels of serum tumor markers, longer median progression-free survival and overall survival, and acceptable and controllable adverse reaction incidence with no significant difference from the control group (P<0.05). Cox regression confirmed that combined therapy was an independent protective factor for improving tumor prognosis (HR=0.412, 95%CI: 0.275-0.618, P<0.001). Conclusion: Lenvatinib combined with interventional therapy can significantly enhance the short-term anti-tumor effect, prolong patient survival time, and maintain controllable safety, which is a reliable and high-value comprehensive treatment scheme for intermediate and advanced malignant tumors. 展开更多
关键词 Lenvatinib Interventional Therapy Malignant Tumor Clinical Efficacy
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Contrast-enhanced ultrasound in evaluating the curative effect of interventional therapy in patients with liver cancer 认领 引用
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作者 Li-Ping Chen Yan Dong +2 位作者 Jing-Guang He Qing-Qing Yang Zhi-Wen Hu 《World Journal of Gastrointestinal Oncology》 SCIE 2025年第8期256-266,共11页
BACKGROUND Contrast-enhanced ultrasonography(CEUS)is utilized to assess the therapeutic efficacy of interventional therapy in liver cancer patients,offering insights into tumor blood flow changes,angiogenesis,and tumo... BACKGROUND Contrast-enhanced ultrasonography(CEUS)is utilized to assess the therapeutic efficacy of interventional therapy in liver cancer patients,offering insights into tumor blood flow changes,angiogenesis,and tumor markers.AIM To evaluate the use of CEUS in examining the effectiveness of interventional therapy for liver cancer,we aim to investigate its diagnostic utility for tumor perfusion patterns,microvessel density,perfusion recovery,blood flow enhancement response,and alterations in tumor markers among patients receiving interventional therapy for liver cancer.METHODS The study involved 124 patients who underwent interventional therapy for liver cancer at Guangzhou First People’s Hospital from January 2022 to February 2024.All patients were examined using CEUS before treatment and at 1 month,3 months,and 6 months,and the concentrations of tumor markers were collected and statistically analyzed using Statistical Package for the Social Sciences 25.0.Receiver operating characteristic(ROC)curves were used to evaluate the diagnostic efficacy of CEUS and analyze its sensitivity,specificity,and correlation with clinical indicators.RESULTS Before treatment,tumor blood flow was primarily enhanced.After treatment,enhanced perfusion declined,while uniform and non-uniform perfusion increased,indicating reduced tumor activity.Enhanced perfusion decreased from 68.25%before treatment to 53.75%at 6 months post-treatment(F=6.123,P=0.016),indicating reduced tumor activity.The microvessel density of the tumors decreased significantly after treatment(P<0.05),and the proportion of low microvessel density increased.After treatment,perfusion recovery in the tumor area improved,the proportion of complete and partial responses gradually increased,and the proportion of stable lesions decreased(P<0.05).The levels of alphafetoprotein,carcinoembryonic antigen,and carbohydrate antigen 19-9 decreased by 68.7%,30.4%,and 41.6%,respectively,at 6 months post-treatment(P<0.05).CEUS showed a sensitivity of 85.72%,specificity of 92.31%,and area under the curve of 0.911(95%CI:0.883–0.939)for evaluating treatment response.ROC curve analysis showed that CEUS had high sensitivity and specificity and could effectively evaluate the efficacy of interventional therapy for liver cancer.CONCLUSION CEUS has high diagnostic value in evaluating therapeutic effects in patients with liver cancer following interventional therapy.It can reflect changes in tumor blood flow,angiogenesis,and tumor marker levels,providing an effective basis for real-time monitoring of treatment outcomes. 展开更多
关键词 Contrast-enhanced ultrasound Liver cancer Interventional therapy Blood perfusion Tumor microvessel density Tumor markers Alpha-fetoprotein Perfusion recovery Receiver operating characteristic curve
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Systemic complications and management strategies in liver cancer patients undergoing interventional therapy 认领 引用
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作者 Yue-Zhan Shan Yan Jiao +1 位作者 Hui-Ling Guo Ya-Hui Liu 《World Journal of Gastrointestinal Surgery》 SCIE 2025年第6期12-19,共8页
Liver cancer presents unique challenges due to its systemic impact and complex treatment modalities.Patients often experience a range of complications,including cardiovascular,renal,hematological,and metabolic abnorma... Liver cancer presents unique challenges due to its systemic impact and complex treatment modalities.Patients often experience a range of complications,including cardiovascular,renal,hematological,and metabolic abnormalities,which can significantly affect treatment outcomes and quality of life.This article emphasizes the integration of multidisciplinary strategies and artificial intelligence-driven diagnostics,which have the potential to improve patient outcomes by optimizing early detection and targeted management of these complications.A recent study on 60 liver cancer patients undergoing interventional therapy highlighted the importance of recognizing and managing these complications.This article offers an overview of systemic complications in liver cancer,focusing on pathophysiological mechanisms,risk factors,and strategies to improve care.By addressing gaps in the existing literature and proposing future research directions,it underscores the importance of comprehensive,patient-centered approaches to refine therapeutic strategies. 展开更多
关键词 Liver cancer Interventional therapy Systemic complications Risk factors Multidisciplinary care
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Observation on the Effect of Interventional Therapy Combined with Lenvatinib and Sintilimab in the Treatment of Advanced Liver Cancer 认领 引用
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作者 Yana Gao Jiao He Qiliang Xu 《Proceedings of Anticancer Research》 2025年第3期69-74,共6页
Objective:To observe the control effect of interventional therapy combined with lenvatinib and sintilimab in patients with intermediate and advanced liver cancer.Methods:82 patients with intermediate and advanced live... Objective:To observe the control effect of interventional therapy combined with lenvatinib and sintilimab in patients with intermediate and advanced liver cancer.Methods:82 patients with intermediate and advanced liver cancer who visited from January 2022 to January 2025 were selected as samples and randomly divided into two groups.Group A received interventional therapy combined with lenvatinib and sintilimab,while Group B received interventional therapy combined with lenvatinib.Disease remission rate,adverse reactions,liver function indicators,and tumor marker indicators were compared between the two groups.Results:The disease control rate(DCR)in Group A was higher than that in Group B(P0.05).Total bilirubin(TBil),aspartate aminotransferase(AST),and alanine aminotransferase(ALT)levels in Group A were lower than those in Group B(P<0.05).Carcinoembryonic antigen(CEA),alpha-fetoprotein(AFP),and alpha-L-fucosidase(AFU)levels in Group A were also lower than those in Group B(P<0.05).Conclusion:Intermediate and advanced liver cancer patients receiving interventional therapy combined with lenvatinib and sintilimab showed reduced tumor marker levels,lessened liver function damage,and a high disease control rate and treatment safety. 展开更多
关键词 Intermediate and advanced liver cancer Sintilimab Lenvatinib Interventional therapy
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Effects of Standardized Bronchoscopic Interventional Therapy on Efficacy and Degree of Stenosis in Patients with Airway Stenosis 认领 引用
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作者 Jiahe Wang Wei Ji +2 位作者 Xuehui Mou Hongjuan Lyu Chen Chen 《Journal of Clinical and Nursing Research》 2025年第5期173-179,共7页
Objective:To analyze the treatment effect of standardized bronchoscopic interventional therapy(i.e.,interventional therapy)on airway stenosis.Methods:Forty patients with airway stenosis admitted to the hospital betwee... Objective:To analyze the treatment effect of standardized bronchoscopic interventional therapy(i.e.,interventional therapy)on airway stenosis.Methods:Forty patients with airway stenosis admitted to the hospital between September 2022 and September 2024 were selected and randomly divided into two groups using a random number table.The experimental group received interventional therapy,while the reference group received conventional treatment.The total effective rate,degree of airway stenosis,shortness of breath score,and lung function indicators were compared.Results:The total effective rate in the experimental group was higher than that in the reference group.The proportion of mild stenosis in the degree of airway stenosis was higher in the experimental group than in the reference group.The shortness of breath score was lower in the experimental group than in the reference group.The lung function indicators were better in the experimental group than in the reference group(P<0.05).Conclusion:Interventional therapy is effective for patients with airway stenosis,as it can reduce the degree of stenosis,improve symptoms of shortness of breath,and protect patients’lung function. 展开更多
关键词 Standardized bronchoscopic interventional therapy Airway stenosis Therapeutic effect Degree of stenosis
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Application of MBSR Combined with Relaxation Training in the Perioperative Period of Interventional Therapy for Lumbar Disc Herniation 认领 引用
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作者 Dan Xiao Qiujin Hao +2 位作者 Yana He Zhixin Liu Xiaoqing Zhang 《Journal of Clinical and Nursing Research》 2025年第10期121-129,共9页
Objective:To explore the application effect of MBSR combined with relaxation training in the perioperative period of radiofrequency ablation combined with ozone interventional therapy for lumbar disc herniation.Method... Objective:To explore the application effect of MBSR combined with relaxation training in the perioperative period of radiofrequency ablation combined with ozone interventional therapy for lumbar disc herniation.Methods:90 patients with lumbar disc herniation who underwent radiofrequency ablation(RFA)combined with ozone interventional therapy in the Orthopedics and Traumatology Department of our hospital from January to December 2019 were included as research samples.They were randomly divided into two groups using a random number table method:the control group(45 cases)received routine perioperative nursing and health education;the experimental group(45 cases)received a comprehensive psychological intervention program consisting of MBSR combined with relaxation training in addition to the control group’s treatment.Changes in pain perception(VAS),sleep quality(PSQI),psychological state(SAS/SDS),and life satisfaction(SWLS)were compared between the two groups before and after the intervention.Results:After the intervention,both groups showed a significant decrease in SAS and SDS scores(P<0.05),with a greater decrease in the experimental group(P<0.05);the experimental group had lower PSQI total scores and scores in each dimension compared to the control group(P<0.05);the experimental group had a significantly lower VAS score(3.56±0.88)compared to the control group(5.94±0.62)(P<0.05);the experimental group had a higher SWLS score(28.59±5.61)compared to the control group(22.46±4.15)(P<0.05).Conclusion:MBSR combined with relaxation training can significantly optimize the perioperative psychological state of patients undergoing RFA combined with ozone interventional therapy,reduce pain sensitivity and stress responses,and simultaneously improve sleep quality and treatment satisfaction. 展开更多
关键词 MBSR Radiofrequency ablation combined with ozone interventional therapy Relaxation training
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Comparison of therapeutic effectiveness of combined interventional therapy for 1126 cases of primary liver cancer 认领 引用 被引量：10
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作者 Ya-Min Liu Hao Qin +2 位作者 Chong-Bao Wang Xiao-Hong Fang Qing-Yong Ma 《World Journal of Gastroenterology》 SCIE CAS 2006年第31期5060-5063,共4页
AIM： To verify the effect of combined interventiona therapy for hepatocellular carcinoma （HCC）. METHODS： The clinical data of 1126 HCC patients who received combined interventional therapy for transcatheter arteri... AIM： To verify the effect of combined interventiona therapy for hepatocellular carcinoma （HCC）. METHODS： The clinical data of 1126 HCC patients who received combined interventional therapy for transcatheter arterial chemoembolization （TACE） before or after hepatectomy, TACE and radio-frequency ablation （RFA）, Chinese medicine treatment and biotherapy after TACE or transcatheter arterial infusion （TAI）, were reviewed according to the results of their liver function, alpha-fetoprotein, image data, color-ultrosonography finding and survival rate. RESULTS： A total of 874 patients were followed up for a period of 2 to 63 mo. The overall 1-, 3- and 5- year survival rates were 67.8%, 28.7% and 18.8% respectively. The 1- 3- and 5- year survival rates of patients who received TACE were 74.7%, 41.4%, 36.9% before hepatectomy and 78.9%, 40.4%, 37.5% after hepatectomy. The effective rate （PR ＋ NC） after TACE and RFA was 93.4%, the 1- and 3- year survival rates were 74.5% and 36.8% after TACE and RFA. The effective rate of PR ＋ NC after TACE was 83.2%. The 1-, 3- and 5- year survival rates were 69.3%, 21.7%, 8.4% after TACE. The effective rate of PR ＋ NC after TAI was 27.5%, the 1- and 2- year survival rates were 11.6% and 0% after TAI. The liver function, color-ultrosonography finding and alpha-fetoprotein after TACE ＋ RFA, TACE and TAI were compared. There was no significant difference in each index between TACE and RFA or TACE as well as in liver function between TACE and RFA or between TACE and TAI. CONCLUSION： The therapeutic effectiveness of TACE before or after hepatectomy is most significant, while the effect of TACE and RFA is better than that of TACE, and the effect of TAI is minimal. 展开更多
关键词 Hepatocellular carcinoma Transcatheter arterial chemoembolization Combined interventional therapy Survival analysis
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Effect of medical care linkage-continuous management mode in patients with posterior circulation cerebral infarction undergoing endovascular interventional therapy 认领 引用 被引量：17
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作者 Fen-Xia Zhu Qian Ye 《World Journal of Clinical Cases》 SCIE 2022年第29期10478-10486,共9页
BACKGROUND Acute cerebral infarction is a severe type of ischemic stroke that can be divided into anterior circulation cerebral infarction and posterior circulation cerebral infarction(PCCI).PCCI affects the structure... BACKGROUND Acute cerebral infarction is a severe type of ischemic stroke that can be divided into anterior circulation cerebral infarction and posterior circulation cerebral infarction(PCCI).PCCI affects the structure of the posterior circulation brain,because posterior part of the brain,which has more complex anatomical structures and more prone to posterior circulation vascular variation.Therefore,improving the prognosis of PCCI patients is necessary.AIM To explore the effect of medical care linkage-continuous management mode(MCLMM)on endovascular interventional therapy(EIT)for PCCI.METHODS Sixty-nine patients with PCCI who received EIT and conventional nursing intervention were selected as the control group,and 78 patients with PCCI who received EIT and MCLMM intervention were selected as the observation group.The incidence of postoperative complications,compliance and disease selfmanagement behavior after six months of intervention,modified Rankin scale(mRS)and Barthel index(BI)scores in the acute phase and after one year of intervention,and recurrence within one year were compared between the two groups.RESULTS The total incidence rate of postoperative complications in the observation group(7.69%)was lower than that in the control group(18.84%)(P<0.05).The scores for medical compliance behavior(regular medication,appropriate diet,and rehabilitation cooperation rates)and disease self-management behavior(self-will,disease knowledge,and self-care ability)in the observation group were higher than those in the control group(P<0.05).After one year of intervention,in the observation group,the mRS score was significantly lower,and the BI score was significantly higher than those in the control group(P<0.05).The recurrence rate within one year in the observation group(3.85%)was significantly lower than that in the control group(13.04%)(P<0.05).CONCLUSION MCLMM can reduce the incidence of complications after EIT for PCCI,improve patient compliance behavior and disease self-management ability,and promote the recovery of neurological function. 展开更多
关键词 Medical care linkage-continuous management mode Posterior circulation cerebral infarction Cerebral infarction Medical care Interventional therapy
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Role of interventional therapy in hepatic artery stenosis and non-anastomosis bile duct stricture after orthotopic liver transplantation 认领 引用 被引量：2
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作者 Da-Bing Zhao Hong Shan +7 位作者 Zai-Bo Jiang Ming-Sheng Huang Kang-Shun Zhu Gui-Hua Chen Xiao-Chun Meng Shou-Hai Guan Zheng-Ran Li Jie-Sheng Qian 《World Journal of Gastroenterology》 SCIE CAS 2007年第22期3128-3132,共5页
AIM： To analyze the clinical manifestations and the effectiveness of therapy in patients with orthotopic liver bansplantation （OLT）-associated hepatic artery stenosis （HAS） and non-anastomosis bile duct stricture... AIM： To analyze the clinical manifestations and the effectiveness of therapy in patients with orthotopic liver bansplantation （OLT）-associated hepatic artery stenosis （HAS） and non-anastomosis bile duct stricture.METHODS： Nine cases were diagnosed as HAS and non-anastomosis bile duct stricture. Percutaneous transluminal angioplasty （PTA） was performed in four HAS cases, and expectant treatment in other five HAS cases, percutaneous transhepatic bile drainage, balloon dilation, stent placement were performed in all nine cases.RESULTS： Diffuse intra- and extra-bile duct stricture was observed in nine cases, which was associated with bile mud siltation and biliary infection. Obstruction of the bile duct was improved obviously or removed. Life span/ follow-up period was 13-30 mo after PTA of four HAS cases, 6-23 mo without PTA of other five cases.CONCLUSION： Progressive, non-anastomosis, and diffuse bile duct stricture are the characteristic manifestations of HAS and non-anastomosis bile duct stricture after OLT. These are often associated with bile mud siltation, biliary infection, and ultimate liver failure. Interventional therapy is significantly beneficial. 展开更多
关键词 Liver transplantation Bile duct Postoperative complication Stricture Interventional therapy
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A traditional Chinese herbal medicine compound preparation versus interventional therapy after resection of small hepatocellular carcinoma:22-year follow-up 认领 引用 被引量：13
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作者 孙振 梁水庭 +7 位作者 翟笑枫 郎庆波 周庆辉 岳小强 贺佳 徐静 朱役 凌昌全 《Journal of Traditional Chinese Medicine》 SCIE CSCD 2012年第2期156-163,共8页
OBJECTIVE:To compare the long-term effectiveness of compound Ruanjianhugan(RJH)tablets and interventional therapy(IT) in patients after resection of small hepatocellular carcinoma(HCC).METHODS:A retrospective study wa... OBJECTIVE:To compare the long-term effectiveness of compound Ruanjianhugan(RJH)tablets and interventional therapy(IT) in patients after resection of small hepatocellular carcinoma(HCC).METHODS:A retrospective study was conducted in 399 patients after resection of small HCC who were admitted between January 1987 and December 2008 in the Department of Hepatobiliary Surgery and Center of Minimlly Invasive Surgery,First Affiliated Hospital of Guangxi Medical University.Four groups were based on different therapy modes:a TCM-only(TCMO) group,a TCM combined with interventional therapy(TCM-IT) group,an interventional therapy-only(ITO) group,and a simple operation(SO) group.Prognostic factors were correlated with overall survival(OS) and OS rates were calculated with the Kaplan-Meier method,and multivariate analyses for factors affecting survival were evaluated by the Cox proportional hazard model.RESULTS:The median OS was 151.20 months in the TCM-IT group,43.87 months in the ITO group,and 20.77 months in the SO group.All survival rates of the TCMO group were higher than those of the other three groups(>50%).The 5-,10-,and 15-year OS in the TCMO and ITO patients were 83.94%,45.50%,and 71.22% and 33.34%,55.58%,and 9.26%,respectively(risk ratio,0.209;95% confidence interval,0.126-0.347;P=0.000).Multivariate analysis revealed that the independent risk factors were therapy mode(P=0.000),sex(P=0.005),family history(P=0.011),TNM Classification of Malignant Tumor staging(P=0.000),medical care-seeking behavior(P=0.021),and maximum diameter(P=0.030).CONCLUSION:Long-term oral use of compound RJH tablets may improve OS for small HCC after resection compared with IT. 展开更多
关键词 Hepatocellular carcinoma Interventional therapy Herbal therapy Traditional Chinese medicine Prognostic factors
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In advanced pancreatic cancer: The value and significance of interventional therapy 认领 引用 被引量：8
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作者 Chao Hu Maoquan Li 《Journal of Interventional Medicine》 2020年第3期118-121,共4页
Pancreatic cancer is famous as“the king of cancer”due to its high degree of malignancy,rapid course of disease development,and poor prognosis.Relevant epidemiological studies have indicated that with improvement in ... Pancreatic cancer is famous as“the king of cancer”due to its high degree of malignancy,rapid course of disease development,and poor prognosis.Relevant epidemiological studies have indicated that with improvement in people’s standard of living,the morbidity and mortality of pancreatic cancer has increased.At the same time,the disease shows an obvious upward trend worldwide.Pancreatic cancer has become a major public health problem that seriously affects the life and health of people.The present review focuses on the recent advances in interventional therapy such as transcatheter arterial infusion,radiofrequency ablation,microwave ablation,and irreversible electroporation of pancreatic cancer. 展开更多
关键词 Pancreatic cancer Interventional therapy Progress
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Landscape of transarterial chemoembolization represented interventional therapy for hepatocellular carcinoma 认领 引用 被引量：1
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作者 Yang-Yang Fu Wen-Mao Li +1 位作者 Hong-Qiao Cai Yan Jiao 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第12期3903-3906,共4页
This article discusses the article written by Tan et al.Transarterial chemoembol-ization(TACE)is one of the main treatment methods for advanced hepatocellular carcinoma(HCC).There are other vascular interventional the... This article discusses the article written by Tan et al.Transarterial chemoembol-ization(TACE)is one of the main treatment methods for advanced hepatocellular carcinoma(HCC).There are other vascular interventional therapies,including drug-eluting bead TACE,transarterial radioembolization,and hepatic arterial infusion chemotherapy.TACE combined with anti-angiogenesis therapy may improve tumor control and prolong progression free survival.The combination therapy of TACE and immunotherapy may improve the clinical efficacy of HCC.In future research,more basic and clinical studies are needed to explore the immunogenic intervention therapy. 展开更多
关键词 Transarterial chemoembolization Interventional therapy Hepatocellular carcinoma Anti-angiogenesis Immunotherapy Programmed cell death 1
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Magnesium metal and its corrosion products:Promising materials for tumor interventional therapy 认领 引用 被引量：6
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作者 Binghui Xu Yuna Song +4 位作者 Kairan Yang Yichen Li Bendong Chen Xia Liao Qingan Jia 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2023年第3期763-775,共13页
Magnesium is generally known to degrade in aqueous environments by an electrochemical reaction.The corrosion products of magnesium include hydrogen gas,Mg2+,and Mg(OH)2.Here,we summarize the published literature... Magnesium is generally known to degrade in aqueous environments by an electrochemical reaction.The corrosion products of magnesium include hydrogen gas,Mg2+,and Mg(OH)2.Here,we summarize the published literature describing the corrosion characteristics of magnesium,and the antitumor properties of magnesium-associated corrosion products,aiming to induce the therapeutic properties of magnesium and magnesium alloys in solid tumors.The therapeutic potential of corrosion products of magnesium is enormous.Hydrogen gas exhibits antioxidant and anti-inflammatory properties,which amount to potential anti-tumor characteristics.Mg(OH)2,which creates a localized alkaline microenvironment,represents a second approach for anti-tumor therapy with magnesium metal.Upregulated concentrations of Mg2+ions in the local tumor microenvironment remodelling are considered a third approach for anti-tumor therapy.Therefore,we speculate about the different physical forms of magnesium that could create an anti-tumor microenvironment upon tumor interventional therapy,a technique that precisely places anti-tumor implants like particles and stents.Finally,we present our viewpoints on the potential use of magnesium in diverse solid tumor therapies to inhibit tumor progression. 展开更多
关键词 Magnesium Hydrogen gas Mg(OH)2 Mg2+ Cancer Interventional therapy
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Minimally invasive interventional therapy for pain 认领 引用 被引量：11
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作者 Yingjie Hua Dan Wu +6 位作者 Tian Gao Lu Liu Yanyu He Yiming Ding Qiaoying Rao Qiaohong Wu Zhongwei Zhao 《Journal of Interventional Medicine》 2023年第2期64-68,共5页
Pain interventional therapy,known as the most promising medical technology in the 21st century,refers to clinical treatment technology based on neuroanatomy,neuroimaging,and nerve block technology to treat pain diseas... Pain interventional therapy,known as the most promising medical technology in the 21st century,refers to clinical treatment technology based on neuroanatomy,neuroimaging,and nerve block technology to treat pain diseases.Compared with traditional destructive surgery,interventional pain therapy is considered a better and more economical choice of treatment.In recent years,a variety of minimally invasive pain interventional therapy techniques,such as neuroregulation,spinal cord electrical stimulation,intervertebral disc ablation,and intrasheath drug infusion systems,have provided effective solutions for the treatment of patients with post-herpetic neuralgia,complex regional pain syndrome,cervical/lumbar disc herniation,and refractory cancer pain. 展开更多
关键词 Interventional therapy Nerve regulation Spinal cord stimulation Discogenic pain Intrathecal drug delivery system
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Composite Configuration Interventional Therapy Robot for the Microwave Ablation of Liver Tumors 认领 引用 被引量：5
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作者 Ying-Yu Cao Long Xue +4 位作者 Bo-Jin Qi Li-Pei Jiang Shuang-Cheng Deng Ping Liang Jia Liu 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2017年第6期1416-1425,共10页
The existing interventional therapy robots for the microwave ablation of liver tumors have a poor clinical applicability with a large volume, low positioning speed and complex automatic navigation control. To solve ab... The existing interventional therapy robots for the microwave ablation of liver tumors have a poor clinical applicability with a large volume, low positioning speed and complex automatic navigation control. To solve above problems, a composite configuration interventional therapy robot with passive and active joints is developed. The design of composite configuration reduces the size of the robot under the premise of a wide range of movement, and the robot with composite configuration can realizes rapid positioning with operation safety. The cumulative error of positioning is eliminated and the control complexity is reduced by decoupling active parts. The navigation algo- rithms for the robot are proposed based on solution of the inverse kinematics and geometric analysis. A simulation clinical test method is designed for the robot, and the functions of the robot and the navigation algorithms are verified by the test method. The mean error of navigation is 1.488 mm and the maximum error is 2.056 mm, and thepositioning time for the ablation needle is in 10 s. The experimental results show that the designed robot can meet the clinical requirements for the microwave ablation of liver tumors. The composite configuration is proposed in development of the interventional therapy robot for the microwave ablation of liver tumors, which provides a new idea for the structural design of medical robots. 展开更多
关键词 Robot Composite configuration Interventional therapy Decoupling mechanismIntelligent positioning Composite configuration
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Interventional therapy for chronic simple atherosclerotic occlusive disease of lower extremity 认领 引用
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作者 Liu Yamin Han Hui Qin Hao Yu Li Zhang Min Feng Jun 《Journal of Medical Colleges of PLA(China)》 2010年第4期212-219,共8页
Objective： To explore the efficacy of interventional therapy for chronic atherosclerotic occlusive disease of the lower extremity. Methods： Fifty-six cases of simple atherosclerotic occlusive disease of lower extrem... Objective： To explore the efficacy of interventional therapy for chronic atherosclerotic occlusive disease of the lower extremity. Methods： Fifty-six cases of simple atherosclerotic occlusive disease of lower extremity were divided into 3 types according to the location of occhision, including 17 cases of abdominal aorta-iliac artery, 18 cases of iliac-femoral artery, and 21 cases of inferior popliteal artery. Catheter and guide wire combined with blunt dissection and subtle banding were used to dredge the occluded vessels, and stents were implanted when interlayer appeared. Results： After the treatment, 46 cases of occlusion were dredged （82.1%）, 6 cases remained occluded with the same symptoms （10.7%）, and 4 cases had severer symptoms （7.1%）. Among the 46 successful cases, there were 16 cases of abdominal aorta-iliac artery （94.1%）, 16 cases of iliac-femoral artery （88.9%） and 14 cases of inferior popliteal artery, artery （66.6%）. There was no statistical difference between the abdominal aorta-iliac artery cases and iliac-femoral artery cases （P〉0.05）, but there was statistical difference between these two types and the inferior popliteal artery cases （P〈0.05）. In the successful cases, 9 cases of abdominal aorta-iliac artery （52.9%）, 10 cases of iliac-femoral artery （55.5%） and 10 cases of inferior popliteal artery （33.3%） had 5-10 cm of occlusion, with no statistical difference between the first two types （P〉0.05）, but with statistical difference between the first two types and the third type （P〈0.05）. Compared with the 14 dredged cases （71.4%）, the 7 cases （33.3%） of inferior popliteal artery cases had richer compensatory circulation （P〈0.05）. Conclusion： It＇s safe and effective to treat simple atherosclerotic occlusive disease of the lower extremity with interventional therapy. The location and length of occlusion and the abundance of compensatory circulation had effect on the therapy. 展开更多
关键词 Atherosclerosis Lower extremity occlusion Interventional therapy
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Expert consensus on interventional therapy for traumatic splenic bleeding 认领 引用 被引量：4
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作者 Huangxing Cai Lingyun Zhang Hua Xiang 《Journal of Interventional Medicine》 2020年第3期109-117,共9页
This study aims to introduce the diagnosis and treatment processes of traumatic splenic bleeding and explain its emergency,medical,interventional,and surgical treatments.Furthermore,this study aims to summarize the in... This study aims to introduce the diagnosis and treatment processes of traumatic splenic bleeding and explain its emergency,medical,interventional,and surgical treatments.Furthermore,this study aims to summarize the indications and contraindications of splenic artery embolization,interventional procedures,and precautions of complications. 展开更多
关键词 Consensus Interventional therapy Traumatic Splenic bleeding
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Medical and interventional therapy of Kasabach-Merritt phenomenon associated with Kaposiform hemangioendothelioma:A case report 认领 引用 被引量：1
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作者 Yan Zhao Ji Cheng 《Journal of Interventional Medicine》 2023年第3期130-133,共4页
An infant with Kasabach-Merritt Phenomenon(KMP)presented with a giant subcutaneous mass in the right lower limb,severe hypofibrinogenemia,and thrombocytopenia.Glucocorticoids,along with supportive treatments including... An infant with Kasabach-Merritt Phenomenon(KMP)presented with a giant subcutaneous mass in the right lower limb,severe hypofibrinogenemia,and thrombocytopenia.Glucocorticoids,along with supportive treatments including transfusion of blood products and clotting factors,were administered to reverse fatal disseminated intravascular coagulation and acute hemolysis.The glucocorticoid dose was tapered slowly,and sirolimus was added to treat the hemangiomas.The patient subsequently underwent interventional therapy.After 6 months of medical and interventional therapy,the patient was doing well with a normal platelet count,the tumor volume was markedly reduced,and the primary cutaneous lesion became pale pink.Currently,the patient remains on sirolimus,and no recurrence of thrombocytopenia or further growth of the mass was observed after six months of follow-up. 展开更多
关键词 Kasabach-Merritt phenomenon(KMP) Kaposiform hemangioendothelioma(KHE) Sirolimus Interventional therapy
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