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A novel Angle-Constrained Optimization method of Conformal Lattice Structures 认领 引用 被引量:1
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作者 Jun Yan Weibin Xu +2 位作者 Fuhao Wang Sixu Huo Kun Yan 《Computer Modeling in Engineering & Sciences》 SCIE EI 2026年第2期269-295,共27页
Conformal truss-like lattice structures face significant manufacturability challenges in additive manufac-turing due to overhang angle limitations.To address this problem,we propose a novel angle-constrained optimizat... Conformal truss-like lattice structures face significant manufacturability challenges in additive manufac-turing due to overhang angle limitations.To address this problem,we propose a novel angle-constrained optimization method grounded in the global adjustment of nodal coordinates.First,a build direction is selected to minimize the number of violating struts.Then,an angular-constraint matrix is assembled from strut direction vectors,and analytical sensitivities with respect to nodal coordinates are derived to enable efficient constrained optimization under nonlinear angular inequality constraints.Numerical studies on two complex curved-surface lattices demonstrate that all overhang violations are eliminated while only minor changes are induced in global stiffness and strength.In particular,the maximum displacement of an ergonomic insole varies by only 2.87%after optimization.The results confirm the method’s versatility and engineering robustness,providing a practical approach for additive manufacturing-oriented lattice structure design. 展开更多
关键词 Conformal lattice structures additive manufacturing structural optimization complex structures
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A hybrid framework integrating classical computers and quantum annealers for optimisation of truss structures 认领 引用 被引量:1
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作者 Van-Dung Nguyen Erin Kuci +1 位作者 Michel Rasquin Ludovic Noels 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第6期58-75,共18页
This work proposes a hybrid framework combining classical computers with quantum annealers for structural optimisation.At each optimisation iteration of an iterative process,two minimisation problems are formulated,on... This work proposes a hybrid framework combining classical computers with quantum annealers for structural optimisation.At each optimisation iteration of an iterative process,two minimisation problems are formulated,one for the underlying mechanical boundary value problem through the minimisation of the potential energy principle and one to update the design variables.Our hybrid approach leverages the strength of quantum computing to solve these two minimisation problems at each step,thanks to the developed quantum annealing-assisted sequential programming strategy introduced in our previous research.The applicability of the proposed framework is demonstrated through several case studies of truss optimisation,highlighting its capability to perform optimisation with quantum computers.This framework offers a promising direction for future structural optimisation applications,particularly in scenarios where the quantum computer could resolve the size limitations of classical computers due to problem complexities. 展开更多
关键词 Quantum computing Quantum annealing Optimisation Truss structure
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Response of wind turbine loads to multi-scale turbulent structures:a study based on turbulence signals observed in the field 认领 引用 被引量:2
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作者 Yongfen Chai Yan Wang +2 位作者 Haolin Li Jingjing Zhang Jian Zheng 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第2期593-609,共17页
Accurately assessing the impact of turbulence structures on load fluctuation is crucial for the long-term stable operation of wind turbines.Based on turbulence signals observed at the Qingtu Lake Observed Array in Chi... Accurately assessing the impact of turbulence structures on load fluctuation is crucial for the long-term stable operation of wind turbines.Based on turbulence signals observed at the Qingtu Lake Observed Array in China,the aerodynamic load responses of the wind turbine to different turbulence scales are quantitatively analyzed in this study.The results indicate that very large-scale motions(VLSMs)are associated with significant load fluctuations due to its low frequency and high energy characteristics,increasing the risk of extreme loads.Large-scale motions coupled with the natural frequency of wind turbines in the medium frequency range,result in resonance phenomena.Small-scale motions,due to their high-frequency rapid vibration characteristics,cause instantaneous oscillations in wind turbine loads.Furthermore,correlation analysis indicates that the flapwise moment and thrust are most sensitive to VLSMs,while the edgewise moment is less affected by the scale characteristics.It is worth noting that this study is the first to explore the modulation effects of different scales of turbulent structures on the amplitude of wind turbine load fluctuation.It was found that turbulent structures exceeding a scale of 3δ have the most significant impact on modulating the load amplitudes,where δ is the boundary layer thickness,which is 99% of the flow velocity outside the boundary layer.These findings contribute to the enhancement of understanding regarding the load response of wind turbines in multi-scale turbulent environments and provide important references for the optimization of wind turbine design and load control. 展开更多
关键词 Multi-scale turbulent structures Wind turbine load response Field observation experiment Wavelet analyze
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Quantum computing-enhanced topology optimization with stress constraints for truss structures 认领 引用 被引量:2
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作者 Yan Wang Dixiong Yang +1 位作者 Zhenzeng Lei Guohai Chen 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第6期41-57,共17页
Quantum computing,leveraging the properties of quantum physics such as quantum superposition and entanglement,possesses the potential for exponential acceleration compared to classical computing.It can significantly e... Quantum computing,leveraging the properties of quantum physics such as quantum superposition and entanglement,possesses the potential for exponential acceleration compared to classical computing.It can significantly enhance solution efficiency in topology optimization and effectively avoid the entrapment in local optima.This paper proposes a hybrid classical-quantum computing framework to solve the stress-constrained topology optimization problem for truss structures.Initially,structural analyses are performed on a classical computer to determine the stresses of truss members.Then,the optimization problem is formulated through incremental updates of member cross-sectional areas to make it compatible with a quantum annealer.The update strategy consists of a directional-control function and a magnitude-control function.By embedding stress constraints directly into the directional-control function,the original optimization problem is reformulated as a quadratic unconstrained binary optimization model suitable for quantum annealing.To realize a balance between solution accuracy and iteration efficiency,a dynamic strategy for adjusting the magnitude of area increments is proposed.Thus,the quantum annealer can effectively achieve the optimal solutions.When only the access time of the quantum processing unit is considered,the results from 2D and 3D examples of truss topology optimization validate the effectiveness of the proposed framework,and demonstrate the great potential of quantum computing in structural optimization. 展开更多
关键词 Topology optimization Truss structures Quantum computing Quantum annealing algorithm Quadratic unconstrained binary optimization problem
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Large-scale model tests on inclined steel pipe pile retaining structures upon excavation 认领 引用 被引量:1
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作者 Fei Gan Gang Zheng +8 位作者 Meilin Li Junhao Liu Haizuo Zhou Teng Cao Jing Bi Yuanyin Zhang Hongwei Liu Yigang Cen Hong Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第6期4924-4939,共16页
The inclined alternating combination steel pipe pile retaining structure(IACSPPRS)is a cost-effective,environmentally friendly excavation-support system that offers advantages such as ease of construction and reusabil... The inclined alternating combination steel pipe pile retaining structure(IACSPPRS)is a cost-effective,environmentally friendly excavation-support system that offers advantages such as ease of construction and reusability.Despite its demonstrated performance in practice,research on its deformation and load-bearing mechanisms remains limited.This study presents large-scale model tests aimed at evaluating pile head displacements,bending moments,deformations,and axial force distributions during excavation.The findings indicate that,at equivalent excavation depths,IACSPPRS piles exhibit significantly reduced deformations compared to conventional cantilevered piles(CP),thereby demonstrating superior retaining performance.Furthermore,IACSPPRS benefits from the combined effects of tie-back action,gravity,and spatial structural interaction,leading to lower internal forces,reduced displacements,and improved overall stability.The system forms a spatially rigid frame,wherein the outer piles function as tensile anchors and the inner piles act as compressive struts,analogous to an internally braced support system in both load-bearing and deformation behavior.The combined effects of active friction on the outer piles,passive friction on the inner piles,and soil gravity contribute to enhanced anti-overturning capacity.Increasing the inclination angle between piles improves deformation resistance,with an optimal angle of about 20°under spatial constraints.The order of retaining performance effectiveness is as follows:vertical-inclined alternating composite piles(VICP),inclined-vertical alternating composite piles(IVCP),and inclined alternating composite piles(IICP). 展开更多
关键词 Excavations Inclined alternating combination steel pipe pile Braceless retaining structure Model tests
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Distinctive mechanical responses of strut-based and triply periodic minimal surface(TPMS)Ti-6Al-4V diamond lattice structures produced by electron beam melting 认领 引用 被引量:1
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作者 Li-Na Zhang Yu Guo +5 位作者 Wu Pan Wen-Ge Xu Cheng-Long Teng Rui-Feng Li Sheng Lu Liang-Yu Chen 《Metals Advances》 SCIE EI CAS CSCD 2026年第3期45-54,共10页
Lattice structures exhibit exceptional specific strength and energy absorption,making them ideal for aerospace and biomedical applications.While both strut-based(Strut-D)and TPMS-based(triply periodic minimal surface-... Lattice structures exhibit exceptional specific strength and energy absorption,making them ideal for aerospace and biomedical applications.While both strut-based(Strut-D)and TPMS-based(triply periodic minimal surface-D)diamond lattice structures show promising mechanical performance,the fundamental differences in their deformation mechanisms and mechanical behavior remain unclear.In this work,Ti-6Al-4V Strut-D and TPMS-D structures with 20%volume fraction were fabricated via electron beam melting(EB-PBF)and their compressive behavior and microstructure were systematically investigated.Compared to Strut-D,TPMS-D structures demonstrate superior mechanical properties:elastic modulus increased by 18.0%(1.51 GPa vs 1.28 GPa),compressive strength enhanced by 28.9%(58.4 MPa vs 45.3 MPa),and energy absorption at densification improved by 57.8%(16.1 MJ m-3vs 10.2 MJ m-3).Finite element analysis revealed that the continuous curved surfaces of TPMS-D disperse stress more uniformly,avoiding stress concentration at nodes and enabling more material to bear load.In contrast,Strut-D exhibits localized stress at strut-node junctions,leading to premature failure.This study clarifies the topological influence on mechanical responses and provides insights for designing high-performance lattice structures. 展开更多
关键词 Lattice structure Ti-6Al-4V Electron beam melting Diamond Compressive behavior
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Research progress on bio-inspired composite structures based on ceramic 3D printing:a review 认领 引用
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作者 Dekun Kong Hailong Wu +4 位作者 Qingquan Zhang Dechao Lyu Yumeng Han Zhihui Zhang Luquan Ren 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2026年第3期430-468,共39页
Ceramic materials demonstrate great application potential in multiple fields such as aerospace and biomedical engineering due to their excellent mechanical properties,high-temperature resistance,and good biocompatibil... Ceramic materials demonstrate great application potential in multiple fields such as aerospace and biomedical engineering due to their excellent mechanical properties,high-temperature resistance,and good biocompatibility,but their inherent brittleness and processing defects urgently need to be broken through.Inspired by the biological structures found in nature,the integration of biomimicry and additive manufacturing(AM)technologies offers a new pathway for the innovative design of high-performance ceramic materials.This article systematically reviews the fundamental principles and classifications of ceramic AM technology,focusing on six typical elements of biomimetic structural design:coaxial composite structures,surface reinforcement structures,layered composite structures,porous structures,composite multicomponent structures,and intelligent bionic structures.The review delves into their biomimetic principles,preparation strategies,performance advantages,and research progress.Research indicates that through multiscale topological design and functional integration,these structures can significantly enhance the mechanical properties and environmental adaptability of ceramics.Nevertheless,current technologies still face numerous challenges in balancing manufacturing precision and efficiency,controlling cracks and residual stresses caused by interface defects,ensuring long-term material stability under extreme environments,enhancing intelligent response capabilities,and guaranteeing process scalability and performance consistency in clinical applications.Future research should integrate multidisciplinary approaches to optimize structural design and dynamic response,transforming biomimetic ceramic materials from‘biological replication'to‘performance exceeding',thereby providing theoretical and technical support for the customized development of high-performance ceramic devices. 展开更多
关键词 bio-inspired composite structures ceramic additive manufacturing coaxial composite structures composite multicomponent structures intelligent bionic structures
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Acoustic Absorption Properties of Bio-inspired Stochastic Voronoi Porous Structures 认领 引用
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作者 Wenjiong Chen Hanbin Wang +1 位作者 Zhiqi Li Shutian Liu 《Journal of Bionic Engineering》 SCIE EI CSCD 2026年第3期1736-1750,共15页
Voronoi structures are widely present in nature,and highly ordered Voronoi structures such as honeycomb structures have gained extensive recognition and in-depth research in the field of sound absorption structure des... Voronoi structures are widely present in nature,and highly ordered Voronoi structures such as honeycomb structures have gained extensive recognition and in-depth research in the field of sound absorption structure design.However,Voronoi structures in biological tissues are not all highly ordered.Stochastic Voronoi structures are equally prevalent and exhibit excellent multifunctional properties.To further explore the acoustic value of stochastic Voronoi structures,this study proposes a Voronoi sound absorbing porous structure that features both structural stochasticity and performance robustness.First,a theoretical calculation model is established based on microperforated panel theory and Helmholtz resonance theory,enabling the rapid calculation of the structure’s sound absorption coefficient.Then,a systematic analysis is conducted on the effective conditions for absorption performance robustness from four dimensions:unit number,structural randomness,manufacturing errors,and boundary cutting.Results indicate that there exists a unit number threshold associated with absorption bandwidth in the Voronoi structure.When this threshold is exceeded,the structure can exhibit favorable sound absorption robustness against structural stochasticity,manufacturing errors,and boundary cutting.Experimental verification shows that under significant boundary changes,the structure still maintains an average sound absorption coefficient of approximately 0.8 within an absorption bandwidth of approximately 400 Hz.Its favorable low-frequency broadband sound absorption performance and robustness endow it with promising application prospects in engineering fields where cost control,environmental adaptability,and construction efficiency need to be balanced. 展开更多
关键词 Sound absorption structure Voronoi Structural stochasticity Performance robustness Porous structure
Multi-objective topology optimization for cutout design in deployable composite thin-walled structures 认领 引用
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作者 Hao JIN Ning AN +3 位作者 Qilong JIA Chun SHAO Xiaofei MA Jinxiong ZHOU 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2026年第1期674-694,共21页
Deployable Composite Thin-Walled Structures(DCTWS)are widely used in space applications due to their ability to compactly fold and self-deploy in orbit,enabled by cutouts.Cutout design is crucial for balancing structu... Deployable Composite Thin-Walled Structures(DCTWS)are widely used in space applications due to their ability to compactly fold and self-deploy in orbit,enabled by cutouts.Cutout design is crucial for balancing structural rigidity and flexibility,ensuring material integrity during large deformations,and providing adequate load-bearing capacity and stability once deployed.Most research has focused on optimizing cutout size and shape,while topology optimization offers a broader design space.However,the anisotropic properties of woven composite laminates,complex failure criteria,and multi-performance optimization needs have limited the exploration of topology optimization in this field.This work derives the sensitivities of bending stiffness,critical buckling load,and the failure index of woven composite materials with respect to element density,and formulates both single-objective and multi-objective topology optimization models using a linear weighted aggregation approach.The developed method was integrated with the commercial finite element software ABAQUS via a Python script,allowing efficient application to cutout design in various DCTWS configurations to maximize bending stiffness and critical buckling load under material failure constraints.Optimization of a classical tubular hinge resulted in improvements of 107.7%in bending stiffness and 420.5%in critical buckling load compared to level-set topology optimization results reported in the literature,validating the effectiveness of the approach.To facilitate future research and encourage the broader adoption of topology optimization techniques in DCTWS design,the source code for this work is made publicly available via a Git Hub link:http://gffzz188fe103f8f1460asuknoq906bx9069wf.ffgz.tsg.suse.edu.cn/jinhao-ok1/Topo-for-DCTWS.git. 展开更多
关键词 Composite laminates Deployable structures Multi-objective optimization Thin-walled structures Topology optimization
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Periosteal mitochondria DNA structures drive agingassociated poor skeletal repair 认领 引用 被引量:1
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作者 Yanlin Wu Chuyi Han +9 位作者 Xue Yang Yitian Wang Weidong Tian Quan Yuan Hui Wang Haisheng Wang Bei Yin Ling Ye Feifei Li Fanyuan Yu 《Bone Research》 SCIE CAS CSCD 2026年第3期819-831,共13页
Insufficient skeletal repair is the primary threat of health span and lifespan in elders with increasingly vast global burden;yet,to date,the knowledge of resolving this crisis remains limited.In this study,we address... Insufficient skeletal repair is the primary threat of health span and lifespan in elders with increasingly vast global burden;yet,to date,the knowledge of resolving this crisis remains limited.In this study,we addressed the specific mechanisms underlying agingassociated poor bone repair,which are driven by the mitochondrial DNA structures mitochondrial G-quadruplex(mtG4).We found that mtG4 is spatiotemporal-wisely accumulated within Pdgfra+periosteal mesenchymal stromal/stem cells(PPM)both in healthy and premature aging,which substantially increases cellular senescence and the degenerative alterations of PPM.By utilizing transgenic lineage tracking,PPM organoids formation,mitochondrial transgenic mutation,organoids transplantation,and serial cellular molecular investigations,we reveal that mtG4 in PPM restricts vital mitochondrial genes’transcription to cause mitochondrial dysfunction,which utterly leads to severe mitophagy and cell senescence.These senescent PPM demonstrates impaired stemness and disrupted fate determination,finally phenocopying aging-associated poor bone repair.This study decodes the mitochondrial genomic reasons for insufficient bone repair during aging,which offers insights for developing cell-type-and disease-specific senolytic therapies in the future. 展开更多
关键词 bone repair mitochondrial G quadruplex mitochondrial DNA periosteal mesenchymal stem cells mitochondrial dysfunction insufficient skeletal repair mitochondrial dna structures cellular senescence
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Energy absorption characteristics of additively manufactured sea sponge-inspired lattice structures under low-velocity impact loading 认领 引用
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作者 J Jefferson Andrew Jabir Ubaid +4 位作者 Mohammed Ayaz Uddin Omar Waqas Saadi Kamran Ahmed Khan Rehan Umer Andreas Schiffer 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2026年第1期118-129,共12页
Low-velocity impact tests are carried out to explore the energy absorption characteristics of bio-inspired lattices,mimicking the architecture of the marine sponge organism Euplectella aspergillum.These sea sponge-ins... Low-velocity impact tests are carried out to explore the energy absorption characteristics of bio-inspired lattices,mimicking the architecture of the marine sponge organism Euplectella aspergillum.These sea sponge-inspired lattice structures feature a square-grid 2D lattice with double diagonal bracings and are additively manufactured via digital light processing(DLP).The collapse strength and energy absorption capacity of sea sponge lattice structures are evaluated under various impact conditions and are compared to those of their constituent square-grid and double diagonal lattices.This study demonstrates that sea sponge lattices can achieve an 11-fold increase in energy absorption compared to the square-grid lattice,due to the stabilizing effect of the double diagonal bracings prompting the structure to collapse layer-bylayer under impact.By adjusting the thickness ratio in the sea sponge lattice,up to 76.7%increment in energy absorption is attained.It is also shown that sea-sponge lattices outperform well-established energy-absorbing materials of equal weight,such as hexagonal honeycombs,confirming their significant potential for impact mitigation.Additionally,this research highlights the enhancements in energy absorption achieved by adding a small amount(0.015 phr)of Multi-Walled Carbon Nanotubes(MWCNTs)to the photocurable resin,thus unlocking new possibilities for the design of innovative lightweight structures with multifunctional attributes. 展开更多
关键词 Sea sponge-inspired lattice structures Additive manufacturing Energy absorption Low-velocity impact Lattice structure Nanocomposite
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Energy absorption behavior of mild steel tube-core sandwich structures for rockfall protection 认领 引用
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作者 HUANG Fuyou ZHANG Luqing +3 位作者 ZHOU Jian HAN Zhenhua WANG Song SUN Qihao 《Journal of Mountain Science》 SCIE CSCD 2026年第1期171-187,共17页
Sandwich structures are widely favored for their lightweight,high strength and superior impact mitigation capabilities in blast mitigation and transportation safety applications.Their application in large-scale,high-e... Sandwich structures are widely favored for their lightweight,high strength and superior impact mitigation capabilities in blast mitigation and transportation safety applications.Their application in large-scale,high-energy rockfall protection remains limited due to their relatively low volumetric energy absorption efficiency and the complex fabrication processes of key energy-absorbing components.To address these limitations,this study proposes a novel sandwich structure incorporating mild steel tubes as core energy absorbers to efficiently mitigate highenergy rockfall impacts.A finite element model was developed in LS-DYNA to systematically investigate the deformation and energy absorption behaviors.Comprehensive parametric analyses were conducted to quantify the effects of key design variables,including tube wall thickness,tube spacing(number of tubes),and infill materials.The results demonstrate that increasing tube wall thickness significantly enhances ultimate energy absorption,with 12-mm-thick tubes absorbing 2.2 times more energy than 6-mm-thick tubes.Lateral constraints induced by adjacent tubes improve specific energy absorption per unit displacement by approximately 30%-45%.Furthermore,incorporating infill materials considerably enhances energy absorption,with aluminum foam infills achieving an 81%increase compared to empty tubes.Nevertheless,higher energy absorption capacity typically leads to greater peak impact forces,increasing the number of tubes offers a better balance between energy absorption and impact force,optimizing the structural performance.These findings provide valuable theoretical insights and practical guidelines for designing sandwich structures in civil and infrastructure engineering applications for effective rockfall protection. 展开更多
关键词 Sandwich structure Mild steel tube Rockfall impact Energy absorption Structural optimization
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Synthesis,crystal structures,and antitumor activity of two metal complexes of imidazolyl acylhydrazones 认领 引用
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作者 ZONG Zhihui ZHAO Zijie +5 位作者 HUANG Lei PAN Zhicheng WANG Shan LIANG Lili LIU Huaqing ZHANG Enli 《无机化学学报》 SCIE CAS CSCD 北大核心 2026年第5期1048-1062,共15页
Two complexes[Cd(L)(CH3O)(CH3COO)]·CH3OH·(CH3)2NH(C1)and[Mn(L)Cl2(CH3OH)](C2)were synthesized by reacting a new imidazole-bearing ligand 4-(1H-imidazol-1-yl)-N'-(pyridin-2-ylmethylen... Two complexes[Cd(L)(CH3O)(CH3COO)]·CH3OH·(CH3)2NH(C1)and[Mn(L)Cl2(CH3OH)](C2)were synthesized by reacting a new imidazole-bearing ligand 4-(1H-imidazol-1-yl)-N'-(pyridin-2-ylmethylene)benzohydrazide(L)with cadmium and manganese salts,respectively.The ligand was characterized by 1H NMR and 13C NMR spectroscopy,while the complexes were analyzed by single-crystal X-ray diffraction,powder X-ray diffraction,thermogravimetric analyses,and UV-Vis spectroscopy.Complex C1 features a 1D zigzag chain structure formed by alternating connections of one ligand and one metal ion.In contrast,complex C2 exhibits a mononuclear molecular structure,where each unit consists of one ligand connected to one manganese ion.Both complexes further form a 3D structure through π-π interactions and intermolecular hydrogen bonds.Cell proliferation assays conducted on four tumor cell lines and one normal cell line revealed that both C1 and C2 exhibited significantly stronger inhibition of tumor cell growth compared to the ligand L.Notably,C1 demonstrated superior anti-proliferative activity against A549 and A2780 cells relative to cisplatin,while showing comparable cytotoxicity toward SMMC-7721 cells.Further mechanistic studies indicated that C1 induces apoptosis in both SMMC-7721 and A549 tumor cells,suppresses the invasion and migration of SMMC-7721 cells,and arrests the cell cycle at the G0/G1 phase. 展开更多
关键词 crystal structure imidazole acylhydrazone antitumor apoptosis
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Realization of Polytype Heterostructures via Delicate Structural Transitions from a Doped Mott Insulator 认领 引用
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作者 Yanyan Geng Manyu Wang +9 位作者 Shumin Meng Shuo Mi Chang Li Huiji Hu Jianfeng Guo Rui Xu Fei Pang Wei Ji Weichang Zhou Zhihai Cheng 《Chinese Physics Letters》 SCIE EI CAS CSCD 2026年第3期118-135,共18页
Transition-metal dichalcogenides hosting multiple competing structural and electronic phases are thus ideal platforms for constructing polytype heterostructures with emergent quantum properties.However,controlling pha... Transition-metal dichalcogenides hosting multiple competing structural and electronic phases are thus ideal platforms for constructing polytype heterostructures with emergent quantum properties.However,controlling phase transitions to form diverse heterostructures inside a single crystal remains challenging.In this study,we realize vertical/lateral polytype heterostructures in a hole-doped Mott insulator via thermal annealing-induced structural transitions.Raman spectroscopy,atomic force microscopy and scanning Kelvin probe force microscopy confirm the coexistence of T-H polytype heterostructures.Atomic-scale scanning tunneling microscopy/spectroscopy measurements reveal the transparent effect in 1H/1T vertical heterostructures,where positive bias voltage induces in a pronounced superposition of the√13×√13 CDW of the 1T-layer on the 1H-layer.By systematically comparing the 1T/1H and 1T/1T interfaces,we demonstrate that the metallic 1H-layer induces a Coulomb screening effect on the 1T-layer,suppressing the formation of CDW domain walls and forming more ordered electronic states.These results clarify the interfacial coupling between distinct quantum many-body phases and establish a controllable pathway for constructing two-dimensional polytype heterostructures with tunable electronic properties. 展开更多
关键词 Raman spectroscopy polytype heterostructures structural electronic phases spectroscopyatomic force microscopy thermal annealing structural transitions emergent quantum propertieshowevercontrolling phase transitions constructing polytype heterostructures
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Fault activation and energy accumulation in anti-slip structures under mining disturbance 认领 引用
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作者 Jinguo Lyu Wenhe Han +5 位作者 Tao Yang Yisheng Peng Yishan Pan Lianpeng Dai Xuebin Wang Zhongbei Li 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第7期5057-5075,共19页
In deep mining,fault activation poses a significantsafety risk due to the sudden release of stored energy.Faults capable of accumulating energy often contain heterogeneous,high-shear-strength anti-slip structures that... In deep mining,fault activation poses a significantsafety risk due to the sudden release of stored energy.Faults capable of accumulating energy often contain heterogeneous,high-shear-strength anti-slip structures that markedly alter stress transfer and slip behavior.Consequently,their activation and destabilization mechanisms differ substantially from traditional fault models.This study identifies common types of anti-slip structures through comprehensive investigation and analysis,establishes a novel fault model,and explores the relationships among structure failure,strain energy accumulation,and fault activation using combined theoretical and experimental approaches.Physical similarity simulations were conducted to analyze variations in fault slip,normal stress,shear stress,and activation degree in faults with and without anti-slip structures.Complementary three-dimensional numerical simulations further elucidated the evolution of maximum shear stress and strain energy accumulation during mining.The results show that faults with anti-slip structures initially experience reduced slippage and enhanced stability,but progressive failure of anti-slip segments leads to large-scale fault sliding.Stress concentration occurs in fault zones containing anti-slip structures,which reduce the advance abutment pressure ahead of the longwall face.In contrast,models without such structures show higher stress concentration and greater energy accumulation ahead of the face.In models with anti-slip structures,peak strain energy mainly accumulates at the structure-fault interface,indicating stronger energy storage capacity and higher instability potential.These findingsprovide new insights into dynamic hazards associated with fault activation and establish a basis for predictive modeling and risk mitigation in deep mining. 展开更多
关键词 Anti-slip structure Fault activation Mining disturbance Energy accumulation Stability
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Preface to the Focus Issue on Pathways to Advanced Flexible Electronics:Materials,Structures,and Systems 认领 引用
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作者 Desheng Kong Rongrong Bao +2 位作者 La Li Chunfeng Wang Yue Liu 《Journal of Semiconductors》 EI CAS CSCD 2026年第8期1-4,共4页
Flexible electronics have established themselves as a key frontier in next-generation electronic technologies,driving sustained breakthroughs that span from material design and structural innovation to system-level in... Flexible electronics have established themselves as a key frontier in next-generation electronic technologies,driving sustained breakthroughs that span from material design and structural innovation to system-level integration. 展开更多
关键词 innovation advanced electronics materials systems flexible electronics structures integration material design structural innovation
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Germinal Center–Like Tertiary Lymphoid Structures Mark Immune Responsiveness and Enable Checkpoint Immunotherapy in Bladder Cancer 认领 引用
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作者 Zhihao Yin Xi Zhen +13 位作者 Haonan Li Haiqiang Duan Xiaowei Hu Tianxi Yu Qing Shi Ziyi Liu Yaowei Li Peng Zhang Peng Dai Meihui Zhao Ziqi Wang Changfu Li Di Wang Zhichao Tong 《Oncology Research》 SCIE 2026年第7期595-624,共30页
Backgrounds:Tertiary lymphoid structures(TLSs)are increasingly recognized as modulators of anti-tumor immunity,yet their clinical relevance in bladder cancer remains incompletely understood,partly owing to heterogenei... Backgrounds:Tertiary lymphoid structures(TLSs)are increasingly recognized as modulators of anti-tumor immunity,yet their clinical relevance in bladder cancer remains incompletely understood,partly owing to heterogeneity in their maturation states.Here,we demonstrate that germinal center(GC)–like TLS maturity,rather than TLS presence alone,is closely associated with immune activation and therapeutic response to Programmed Death-Ligand 1(PD-L1)blockade in bladder cancer.The objective of this study was to systematically investigate the clinical significance,biological function,and therapeutic potential of tertiary lymphoid structure(TLS)maturation in bladder cancer.Specifically,we aimed to determine whether GC-like TLS maturity provides prognostic and predictive value beyond TLS presence alone,to elucidate the immune programs and tumor microenvironment remodeling associated with TLS maturation,and to explore whether TLS maturation can be therapeutically induced to enhance responsiveness to PD-L1 blockade.Methods:We performed an integrative analysis combining multi-cohort transcriptomics,spatially resolved histopathology,single-cell RNA sequencing,and functional murine experiments.TLS maturation states were defined using gene-expression–based GC-like TLS signatures and validated through multiplex immunohistochemistry.Clinical relevance was assessed in public immunotherapy cohorts and an independent neoadjuvant PD-L1–treated muscle-invasive bladder cancer(MIBC)cohort.Tumor immune microenvironment remodeling and chemokine-mediated cellular crosstalk were analyzed using deconvolution,Weighted Gene Co-expression Network Analysis(WGCNA),and CellChat.The therapeutic inducibility of TLS maturation was examined using a lymphotoxin-βreceptor(LTβR)agonist in combination with PD-L1 blockade in a syngeneic bladder cancer model.Results:Across multiple transcriptomic cohorts,tumors enriched for GC-like TLS signatures exhibited significantly prolonged survival and higher objective response rates to anti–PD-L1 therapy,whereas less mature TLS phenotypes showed no consistent association with clinical association.These observations were independently validated in a neoadjuvant PD-L1–treated muscle-invasive bladder cancer cohort,in which high mature TLS density was associated with major pathological response and prolonged event-free survival,outperforming PD-L1 expression.Integrative histopathological and transcriptomic analyses indicated that GC formation marks a functional transition linking humoral immune programs with cytotoxic effector activity and shaping a memory-prone,pro-inflammatory tumor immune microenvironment.Chemokine signaling via the CC chemokine ligand 21(CCL21)–C-C chemokine receptor type 7(CCR7)and C-X-C motif chemokine ligand 12(CXCL12)–C-X-C chemokine receptor type 4(CXCR4)axes was strongly associated with TLS maturation and spatial organization.Finally,in a syngeneic bladder cancer model,pharmacological activation of lymphotoxin-βreceptor signaling promoted TLS maturation and enhanced the antitumor efficacy of PD-L1 blockade.Conclusions:Together,these findings suggest that GC-like TLS maturity represents a clinically relevant biomarker and a potential therapeutic entry point for precision immunotherapy in bladder cancer.Therapeutic strategies that promote TLS maturation may convert immune-cold tumors into checkpoint-responsive states,providing a mechanistically grounded precision immunotherapy approach. 展开更多
关键词 Tertiary lymphoid structures bladder cancer germinal center(GC)–like tertiary lymphoid structure tumor microenvironment programmed death-ligand 1
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Fabrication and performance analysis of TC4 pyramidal lattice structures via alternating pin-press and brazing:A study on truss angle optimization 认领 引用
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作者 Hui WANG Rui WANG +2 位作者 Zhongxu LIU Xingrong CHU Kongxun ZHAO 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2026年第7期630-644,共15页
The 3D lattice structure is increasingly recognized in various applications due to its high porosity and excellent mechanical properties.However,fabricating these complex structures,especially using low-plasticity mat... The 3D lattice structure is increasingly recognized in various applications due to its high porosity and excellent mechanical properties.However,fabricating these complex structures,especially using low-plasticity materials like titanium alloys,has posed significant challenges.The alternating pin-press method was successfully applied to produce titanium pyramidal 3D lattice core based on the high temperature forming mold.A brazing fixture was designed to protect the core during brazing,resulting in fully functional TC4 pyramidal 3D lattice structures.The fabrication structure achieved a compressive strength of 2.96 MPa and a relative compressive strength of108.65 MPa at a relative density of 0.0272.Metallographic analysis revealed that forming at 800℃resulted in equiaxedαphase with dispersedβphase,while brazing at 980℃,near theβ-transformation temperature,led to coarseαand strip-likeβphases.Experimental tests and finite element simulations demonstrated the variation in truss rod stiffness constant with geometry,identifying optimal truss angles of 33.4°for maximum flatwise compressive strength of 3.7 MPa and 44.8°for maximum relative compressive strength of 163.7 MPa.These findings offer valuable insights for the design of high-performance,low-density lattice structures in aerospace and related engineering fields. 展开更多
关键词 Compression testing Finite element method Lattice structures Optimization Titanium alloy
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Continuum modeling for layer jamming structures 认领 引用
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作者 Shuai Zhang Jiantao Yao +1 位作者 Shizeng Li Xinbo Chen 《Theoretical & Applied Mechanics Letters》 EI CAS CSCD 2026年第1期77-85,共9页
Layer jamming structures(LJS)are a class of variable stiffness structures that are valuable for adaptive and soft robotic systems.However,existing models for LJS often rely on discrete approximations or are tailored t... Layer jamming structures(LJS)are a class of variable stiffness structures that are valuable for adaptive and soft robotic systems.However,existing models for LJS often rely on discrete approximations or are tailored to specific configurations,limiting their generalizability and computational efficiency.In this study,we propose a contin-uum elastoplastic constitutive model for LJS based on the average-field technique.The model captures both the jamming(no interlayer slipping)and slipping states of LJS,enabling analytical expressions for yield criteria,and dissipated energy density.Finite element simulations in Abaqus incorporating periodic boundary conditions were conducted to validate the theoretical model under various deformation scenarios,including uniaxial shear,multi-directional shear,and coupled shear-normal loading.The results demonstrate strong agreement between numerical and theoretical predictions,effectively capturing the nonlinear transitions in stiffness and energy evo-lution.This continuum framework offers a unified,scalable tool for modeling the mechanical behavior of LJS and supports the design and optimization of stiffness-tunable systems in soft robotics and beyond. 展开更多
关键词 Layer jamming structure Continuum modeling Elastoplastic constitutive
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Nonlinear coupling mechanism of quasi-zero-stiffness units in multi-level structures 认领 引用
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作者 Shaokun YANG Xingxing SHI +2 位作者 Xingzhong WANG Jiuhui WU Fuyin MA 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2026年第6期1215-1240,共26页
Multilayer structures composed of quasi-zero-stiffness(QZS)units exhibit mechanical characteristics distinct from those of a single unit,and their behaviors are governed by the coupling mechanism between the QZS units... Multilayer structures composed of quasi-zero-stiffness(QZS)units exhibit mechanical characteristics distinct from those of a single unit,and their behaviors are governed by the coupling mechanism between the QZS units.This paper introduces the coupling coefficient to quantitatively describe this mechanism,classifying the system into strongly coupled and weakly coupled states.Through theoretical analysis,numerical simulation,and experimental testing,the static and dynamic responses under different coupling states are comparatively investigated.The results show that in the strongly coupled system,the deformation behavior of each QZS unit shows high consistency,leading to a wider QZS region,weaker nonlinear characteristics,and stronger dynamic response.In the weakly coupled systems,the low degree of deformation coordinations among the units results in different QZS regions,enabling low-frequency vibration isolation under varying loads.The analytical approach of the coupling mechanisms and the static and dynamic response behaviors generated by the two coupling mechanisms provide guidance for the structural design of multifunctional and highly adaptable multi-level QZS metamaterials. 展开更多
关键词 multi-level structure coupling mechanism strong coupling weak coupling deformation coordination
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