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Endoscopic treatment of small bowel hemangiomas via doubleballoon enteroscopy:A single-center comparative study 认领 引用
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作者 Wen-Bo Zhu Hua-Bing Huang +5 位作者 Yi-Fan Qiu Yuan-Hang Dong Xin-Tong Zhao Xian-Zhu Zhou Zhao-Shen Li Yi-Qi Du 《World Journal of Gastroenterology》 SCIE CAS 2026年第23期56-66,共11页
BACKGROUND Previous studies have not clarified a universally acknowledged treatment approach that can eradicate small bowel hemangiomas while minimizing harm to patients.Although studies have indicated that endoscopic... BACKGROUND Previous studies have not clarified a universally acknowledged treatment approach that can eradicate small bowel hemangiomas while minimizing harm to patients.Although studies have indicated that endoscopic interventions have promising treatment effects with minimal invasiveness,no comparison of different types of endoscopic therapies has been conducted.AIM To compare the clinical efficacy,safety,and procedural outcomes of lauromacrogol injection,argon plasma coagulation(APC),and endoscopic ligation via double-balloon enteroscopy for the treatment of small bowel hemangiomas,and to identify lesion-specific optimal endoscopic strategies.METHODS Seventy-five participants were enrolled in this study.Thirteen patients received conservative treatment,20 received lauromacrogol injection,22 underwent APC,18 underwent endoscopic ligation therapy,and two received hemostatic clip therapy.Key indicators and prognostic information for different treatment methods were compared between conservative-interventional and within interventional therapies.Categorical variables were compared using theχ2 or Fisher’s exact test,and continuous variables were compared using the Student’s ttest or Wilcoxon rank sum test.RESULTS Compared with conservative therapy,interventional therapy was associated with a lower rebleeding rate.Compared with ligation therapy,lauromacrogol therapy was associated with less intraprocedural bleeding and showed a higher technical success rate and shorter operative duration.Compared with lauromacrogol and ligation therapies,APC was associated with a shorter procedure duration,a higher technical success rate,and less intraprocedural bleeding.CONCLUSION Our observational data suggest that lauromacrogol injection may be a more suitable option for raised small bowel hemangiomas,while APC may be preferable for flat lesions. 展开更多
关键词 Small bowel hemangioma Double-balloon enteroscopy Lauromacrogol injection Argon plasma coagulation Endoscopic ligation Obscure gastrointestinal bleeding
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Research on Integrating Deep Learning-Based Vehicle Brand and Model Recognition into a Police Intelligence Analysis Platform 认领 引用
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作者 Shih-Lin Lin Cheng-Wei Li 《Computers, Materials & Continua》 SCIE EI 2026年第2期785-804,共20页
This study focuses on developing a deep learning model capable of recognizing vehicle brands and models,integrated with a law enforcement intelligence platform to overcome the limitations of existing license plate rec... This study focuses on developing a deep learning model capable of recognizing vehicle brands and models,integrated with a law enforcement intelligence platform to overcome the limitations of existing license plate recognition techniques—particularly in handling counterfeit,obscured,or absent plates.The research first entailed collecting,annotating,and classifying images of various vehiclemodels,leveraging image processing and feature extraction methodologies to train themodel on Microsoft Custom Vision.Experimental results indicate that,formost brands and models,the system achieves stable and relatively high performance in Precision,Recall,and Average Precision(AP).Furthermore,simulated tests involving illicit vehicles reveal that,even in cases of reassigned,concealed,or missing license plates,the model can rely on exterior body features to effectively identify vehicles,reducing dependence on plate-specific data.In practical law enforcement scenarios,these findings can accelerate investigations of stolen or forged plates and enhance overall accuracy.In conclusion,continued collection of vehicle images across broadermodel types,production years,and modification levels—along with refined annotation processes and parameter adjustment strategies—will further strengthen themethod’s applicability within law enforcement intelligence platforms,facilitating more precise and comprehensive vehicle recognition and control in real-world operations. 展开更多
关键词 Deep learning vehicle brand-model recognition license plate anomalies(counterfeit/obscured) law enforcement intelligence data augmentation
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This enterprise dazzles the big screen with its functional gear 认领 引用
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作者 Qiu Shuchen 《China Textile》 2026年第2期24-25,共2页
What is the most unforgettable moment in the film Pegasus 3?It is not the boisterous cheers from the podium,but rather the scene where Zhang Chi—played by Shen Teng—finds his vision completely obscured during the ra... What is the most unforgettable moment in the film Pegasus 3?It is not the boisterous cheers from the podium,but rather the scene where Zhang Chi—played by Shen Teng—finds his vision completely obscured during the race,yet continues to speed across the gravel track,relying solely on his navigator and the tactile instincts honed over years of practice.This represents a skill etched into his very bones—experience forged through countless trials and refinements. 展开更多
关键词 tactile instincts Shen Teng Zhang Chi vision obscured unforgettable moment gravel track navigator Pegasus
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Deep learning meets small-bowel capsule endoscopy: A step toward faster and more consistent diagnosis of obscure gastrointestinal bleeding 认领 引用 被引量：1
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作者 Heng-Rui Liu 《World Journal of Gastrointestinal Endoscopy》 2025年第10期1-3,共3页
Small-bowel capsule endoscopy(SBCE)is the first-line diagnostic tool for obscure gastrointestinal bleeding but is limited by labor-intensive review,reader dependency,and interobserver variability.In this issue,Kwon et... Small-bowel capsule endoscopy(SBCE)is the first-line diagnostic tool for obscure gastrointestinal bleeding but is limited by labor-intensive review,reader dependency,and interobserver variability.In this issue,Kwon et al present a convolutional neural network-based system capable of both gastrointestinal segment localization and multi-lesion detection,erosions/ulcers,angiodysplasia,and bleeding,using full-length SBCE videos.The model achieved>97%localization accuracy and approximately 99%lesion detection accuracy in internal testing,and in external validation reduced reading time from nearly one hour to nine minutes without compromising detection performance.Methodological strengths include a two-step detection-classification pipeline,temporal smoothing,and ensemble learning,closely simulating human reading workflow.Compared with previous artificial intelligence(AI)-SBCE studies,this integrated“localization+detection”approach represents a step toward clinically deployable AI assistance.However,generalizability remains limited by single-platform training,a focus on three lesion types,and modest external validation size.Wider lesion coverage,multiplatform validation,and real-time integration will be essential for broader adoption.This study underscores the potential of AI to improve efficiency and consistency in SBCE interpretation and marks meaningful progress toward its routine clinical use. 展开更多
关键词 Lesion detection Artificial intelligence Deep learning Obscure gastrointestinal bleeding Capsule endoscopy
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Deep learning-based localization and lesion detection in capsule endoscopy for patients with suspected small-bowel bleeding 认领 引用 被引量：3
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作者 Yeong Seok Kwon Tae Yong Park +7 位作者 So Eui Kim Yehyun Park Jae Gon Lee Sang Pyo Lee Kyeong Ok Kim Hyun Joo Jang Young Joo Yang Bum-Joo Cho 《World Journal of Gastroenterology》 SCIE CAS 2025年第27期66-76,共11页
BACKGROUND Small-bowel capsule endoscopy(SBCE)is widely used to evaluate obscure gastrointestinal bleeding;however,its interpretation is time-consuming and reader-dependent.Although artificial intelligence(AI)has emer... BACKGROUND Small-bowel capsule endoscopy(SBCE)is widely used to evaluate obscure gastrointestinal bleeding;however,its interpretation is time-consuming and reader-dependent.Although artificial intelligence(AI)has emerged to address these limitations,few models simultaneously perform small-bowel(SB)loca lization and abnormality detection.AIMTo develop an AI model that automatically distinguishes the SB from the stomach and colon and diagnoses SBabnormalities.METHODSWe developed an AI model using 87005 CE images (11925, 33781, and 41299 from the stomach, SB, and colon,respectively) for SB localization and 28405 SBCE images (1337 erosions/ulcers, 126 angiodysplasia, 494 bleeding,and 26448 normal) for abnormality detection. The diagnostic performances of AI-assisted reading and conventionalreading were compared using 32 SBCE videos in patients with suspicious SB bleeding.RESULTSRegarding organ localization, the AI model achieved an area under the receiver operating characteristic curve(AUC) and accuracy exceeding 0.99 and 97%, respectively. For SB abnormality detection, the performance was asfollows: Erosion/ulcer: 99.4% accuracy (AUC, 0.98);angiodysplasia: 99.8% accuracy (AUC, 0.99);bleeding: 99.9%accuracy (AUC, 0.99);normal: 99.3% accuracy (AUC, 0.98). In external validation, AI-assisted reading (8.7 minutes)was significantly faster than conventional reading (53.9 minutes;P < 0.001). The SB localization accuracies (88.6% vs72.7%, P = 0.07) and SB abnormality detection rates (77.3% vs 77.3%, P = 1.00) of the conventional reading and AIassistedreading were comparable.CONCLUSIONOur AI model decreased SBCE reading time and achieved performance comparable to that of experiencedendoscopists, suggesting that AI integration into SBCE reading enables efficient and reliable SB abnormalitydetection. 展开更多
关键词 Artificial intelligence Obscure gastrointestinal bleeding Capsule endoscopy Detection Localization Small bowel
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Capsule endoscopy:Do we still need it after 24 years of clinical use? 认领 引用
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作者 Ahmed Tawheed Alaa Ismail +2 位作者 Mohab S Amer Osama Elnahas Tawhid Mowafy 《World Journal of Gastroenterology》 SCIE CAS 2025年第5期140-147,共8页
In this letter,we comment on a recent article published in the World Journal of Gastroenterology by Xiao et al,where the authors aimed to use a deep learning model to automatically detect gastrointestinal lesions duri... In this letter,we comment on a recent article published in the World Journal of Gastroenterology by Xiao et al,where the authors aimed to use a deep learning model to automatically detect gastrointestinal lesions during capsule endoscopy(CE).CE was first presented in 2000 and was approved by the Food and Drug Administration in 2001.The indications of CE overlap with those of regular diagnostic endoscopy.However,in clinical practice,CE is usually used to detect lesions in areas inaccessible to standard endoscopies or in cases of bleeding that might be missed during conventional endoscopy.Since the emergence of CE,many physiological and technical challenges have been faced and addressed.In this letter,we summarize the current challenges and briefly mention the proposed methods to overcome these challenges to answer a central question:Do we still need CE? 展开更多
关键词 Capsule endoscopy Wireless capsule endoscopy Obscure gastrointestinal bleeding Artificial intelligence in gastroenterology Therapeutic capsule endoscopy
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Diagnostic yield of video capsule endoscopy vs simple balloon enteroscopy in small intestinal disorders:A systematic review 认领 引用
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作者 Eyad Gadour Bogdan Miutescu +2 位作者 Hussein Hassan Okasha Ana Maria Ghiuchici Mohammed S AlQahtani 《World Journal of Gastrointestinal Endoscopy》 2025年第7期172-180,共9页
BACKGROUND Small-bowel disorders,including obscure gastrointestinal bleeding(OGIB),Crohn's disease,and tumors,require accurate diagnostic approaches for effective treatment.Video capsule endoscopy(VCE)and simple b... BACKGROUND Small-bowel disorders,including obscure gastrointestinal bleeding(OGIB),Crohn's disease,and tumors,require accurate diagnostic approaches for effective treatment.Video capsule endoscopy(VCE)and simple balloon enteroscopy(SBE)are widely used;however,each modality has limitations,particularly regarding therapeutic intervention and diagnostic yield.AIM To evaluate diagnostic yields of various modalities for small bowel bleeding,analyze factors affecting heterogeneity,and improve understanding of clinical outcomes associated with different diagnostic approaches.METHODS A comprehensive search of four databases(PubMed,Embase,Cochrane Library,and Scopus)revealed over 600 citations related to the use of capsule endoscopy and balloon enteroscopy for diagnosing small intestine disorders with wall thickening.Based on predetermined eligibility criteria,seven moderateto-high-quality retrospective studies were analyzed to evaluate the diagnostic performance of VCE and SBE in patients with small bowel disorders.Quality Assessment of Diagnostic Accuracy Studies was applied to evaluate the risk of bias and overall methodological quality.RESULTS Analysis of seven moderate-to-high-quality retrospective studies revealed comparable overall detection rates for small bowel lesions between VCE and SBE.VCE demonstrated superior performance in detecting vascular lesions.Conversely,SBE exhibited a higher efficacy in detecting ulcerative lesions.The overall diagnostic yield varied across studies,with VCE showing a range of 32%–83%for small bowel bleeding,whereas SBE demonstrated a higher overall detection rate of 69.7%compared to 57.6%for VCE(P<0.05).Notably,SBE showed superior performance in diagnosing Crohn's disease,with a detection rate of 35%,compared to 11.3%for VCE(P<0.001).The diagnostic concordance between VCE and SBE was influenced by the lesion type.Strong agreement was observed for inflammatory lesions(κ=0.82,95%CI:0.75-0.89),whereas moderate agreement was noted for tumors(κ=0.61,95%CI:0.52-0.70)and angiectasias(κ=0.58,95%CI:0.49-0.67).SBE demonstrated significant advantages in therapeutic interventions,particularly in overt bleeding.Patient tolerability was generally higher for VCE,with a completion rate of 95%(95%CI:92%-98%),compared to 85%for SBE(95%CI:80%-90%).However,the capsule retention rate for VCE was 1.4%(95%CI:0.8%-2.0%),necessitating subsequent intervention.CONCLUSION VCE and SBE are complementary techniques for evaluating small intestinal disorders.Although VCE remains the initial test of choice for patients with stable OGIB,SBE should be considered in patients requiring therapeutic intervention.Thus,combining both modalities enhances diagnostic accuracy and patient management. 展开更多
关键词 Single balloon enteroscopy Video capsule endoscopy Obscure gastrointestinal bleeding Small intestine disorders Diagnostic yield
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Small bowel ulcers and bleeding:An overlooked yet critical clinical challenge 认领 引用
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作者 Orivaldo Alves Barbosa 《World Journal of Clinical Cases》 2025年第30期1-4,共4页
Gastrointestinal(GI)bleeding originating from the small bowel represents a diagnostic and therapeutic challenge,often demanding advanced imaging techniques for accurate identification.Maity et al present a case of a b... Gastrointestinal(GI)bleeding originating from the small bowel represents a diagnostic and therapeutic challenge,often demanding advanced imaging techniques for accurate identification.Maity et al present a case of a benign ulcerated jejunal GI stromal tumor(GIST)manifesting as overt bleeding,underscoring the importance of considering small bowel neoplasms in obscure GI hemorrhage.Furthermore,recent studies highlight that small intestinal GISTs exhibit more aggressive clinical features compared to gastric GISTs,correlating with worse relapse-free survival and higher rates of GI bleeding.This editorial discusses the implications of these findings and the necessity for comprehensive diagnostic workup in small bowel bleeding. 展开更多
关键词 Gastrointestinal hemorrhage Small intestine neoplasms Intestinal ulcer Gastrointestinal stromal tumor Obscure gastrointestinal bleeding
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Laboratory Application of Laser Grain-Size Analyzer in Determining Suspended Sediment Concentration 认领 引用 被引量：1
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作者 LIU Xiao FENG Xiuli +1 位作者 LIU Jie LIN Lin 《Journal of Ocean University of China》 SCIE CAS 2014年第3期375-380,共6页
Suspended sediment concentration(SSC) is an important parameter in marine sedimentology. With the development of technology, many acoustic and optical devices, such as the Laser In-Situ Scattering and Transmissometry,... Suspended sediment concentration(SSC) is an important parameter in marine sedimentology. With the development of technology, many acoustic and optical devices, such as the Laser In-Situ Scattering and Transmissometry, have been designed to measure in situ SSC and grain size distribution. But due to fund or other restrictions, many experiments were only conducted in laboratory, using an indoor laser grain-size analyzer and gravimetric method to measure grain size distribution and concentration, respectively. In this study the laboratory experiment is simplified by omitting the tiring step of gravimetric method. The connections between SSC and other parameters(obscuration, D50 and sorting index) were investigated based on 124 surface sediment samples collected from different offshore areas. A new method is developed for determining SSC in laboratory using a laser grain-size analyzer. 展开更多
关键词 suspended sediment concentration laser grain-size analyzer grain size parameters obscuration
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Negative capsule endoscopy in patients with obscure gastrointestinal bleeding reliable: Recurrence of bleeding on long-term follow-up 认领 引用 被引量：16
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作者 Maria Elena Riccioni Riccardo Urgesi +4 位作者 Rossella Cianci Gianluca Rizzo Luca D'Angelo Riccardo Marmo Guido Costamagna 《World Journal of Gastroenterology》 SCIE CAS 2013年第28期4520-4525,共6页
AIM: To assess the rate of recurrent bleeding of the small bowel in patients with obscure bleeding already undergone capsule endoscopy (CE) with negative results. METHODS: We reviewed the medical records related to 69... AIM: To assess the rate of recurrent bleeding of the small bowel in patients with obscure bleeding already undergone capsule endoscopy (CE) with negative results. METHODS: We reviewed the medical records related to 696 consecutive CE performed from December 2002 to January 2011, focusing our attention on patients with recurrence of obscure bleeding and negative CE. Evaluating the patient follow-up, we analyzed the recurrence rate of obscure bleeding in patient with a negative CE. Actuarial rates of rebleeding during follow-up were calculated, and factors associated with rebleeding were assessed through an univariate and multivariate analysis. A P value of less than 0.05 was regarded as statistically significant. The sensitivity, specificity, and positive and negative predictive values (PPV and NPV) of negative CE were calculated. RESULTS: Two hundred and seven out of 696 (29.7%) CE studies resulted negative in patient with obscure/overt gastrointestinal bleeding. Overall, 489 CE (70.2%) were positive studies. The median follow-up was 24 mo (range 12-36 mo). During follow-up, recurrence of obscure bleeding was observed only in 34 out of 207 negative CE patients (16.4%); 26 out of 34 with obscure overt bleeding and 8 out of 34 with obscure occult bleeding. The younger age (< 65 years) and the onset of bleeding such as melena are independent risk factors of rebleeding after a negative CE (OR = 2.6703, 95%CI: 1.1651-6.1202, P = 0.0203; OR 4.7718, 95%CI: 1.9739-11.5350, P = 0.0005). The rebleeding rate (CE+ vs CE-) was 16.4% vs 45.1% (χ 2 test, P = 0.00001). The sensitivity, specificity, and PPV and NPV were 93.8%, 100%, 100%, 80.1%, respectively. CONCLUSION: Patients with obscure gastrointestinal bleeding and negative CE had a significantly lower rebleeding rate, and further invasive investigations can be deferred. 展开更多
关键词 Capsule endoscopy Enteroscopy Anemia Obscure gastrointestinal bleeding Rebleeding
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Bleeding Dieulafoy's-like lesions of the gut identified by capsule endoscopy 认领 引用 被引量：10
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作者 Lidia Ciobanu Oliviu Pascu +3 位作者 Brindusa Diaconu Daniela Matei Cristina Pojoga Marcel Tantu 《World Journal of Gastroenterology》 SCIE CAS 2013年第29期4823-4826,共4页
Dieulafoy's-like lesions (DLs-like) represent a cause of obscure gastrointestinal bleeding, enteroscopy being the main diagnostic and therapeutic procedure. Frequently, more than one enteroscopy is needed to ident... Dieulafoy's-like lesions (DLs-like) represent a cause of obscure gastrointestinal bleeding, enteroscopy being the main diagnostic and therapeutic procedure. Frequently, more than one enteroscopy is needed to identify the bleeding vessel. In our practice, video capsule endoscopy (VCE) identified and guided therapy in four cases of DLs-like; three of them were localized on the small bowel. We report, for the first time, a diagnosis of colonic DL-like performed by colon capsule endoscopy. Two patients presented with severe cardiovascular disorders, being hemodynamically unstable during VCE examination. Based on the VCE findings, only one invasive therapeutic procedure per patient was necessary to achieve hemostasis. VCE and enteroscopy may be regarded as complementary procedures in patients with gut DLs-like. 展开更多
关键词 Obscure gastrointestinal bleeding Dieulafoy’ s-like lesion Video capsule endoscopy Enteroscopy Small bowel
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Double-balloon enteroscopy for obscure gastrointestinal bleeding: A single center experience in China 认领 引用 被引量：16
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作者 Chen, Li-Hua Chen, Wen-Guo +10 位作者 Cao, Hai-Jun Zhang, Hong Shan, Guo-Dong Li, Lin Zhang, Bing-Ling Xu, Cheng-Fu Ding, Kai-Li Fang, Ying Cheng, Ying Wu, Chen-Jiao Xu, Guo-Qiang 《World Journal of Gastroenterology》 SCIE CAS 2010年第13期1655-1659,共5页
AIM: To evaluate the diagnostic value of double-balloon enteroscopy (DBE) for obscure gastrointestinal bleeding (OGIB). METHODS: The data about 75 OGIB patients who underwent DBE in January 2007-June 2009 in our hospi... AIM: To evaluate the diagnostic value of double-balloon enteroscopy (DBE) for obscure gastrointestinal bleeding (OGIB). METHODS: The data about 75 OGIB patients who underwent DBE in January 2007-June 2009 in our hospital were retrospectively analyzed. RESULTS: DBE was successfully performed in all 75 patients without complication. Of the 75 patients, 44 (58.7%) had positive DBE findings, 22 had negative DBE findings but had potential bleeding at surgery and capsule endoscopy, etc . These 66 patients were finally diagnosed as OGIB which was most commonly caused by small bowel tumor (28.0%), angiodysplasia (18.7%) and Crohn’s disease (10.7%). Lesions occurred more frequently in proximal small bowel than in distal small bowel (49.3% vs 33.3%, P = 0.047). CONCLUSION: DBE is a safe, effective and accurate procedure for the diagnosis of OGIB. 展开更多
关键词 Double-balloon enteroscopy Capsule endoscopy Obscure gastrointestinal bleeding Diagnosis
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How much helpful is the capsule endoscopy for the diagnosis of small bowel lesions? 认领 引用 被引量：16
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作者 Osman Ersoy Bulent Sivri +2 位作者 Serap Arslan Figen Batman Yusuf Bayraktar 《World Journal of Gastroenterology》 SCIE CAS 2006年第24期3906-3910,共5页
AIM： To assess the practically usefulness and diagnostic yield of this new method in a group of patients with suspected small bowel lesions. METHODS： Capsule endoscopic （CE） examination by using M2A capsule endosc... AIM： To assess the practically usefulness and diagnostic yield of this new method in a group of patients with suspected small bowel lesions. METHODS： Capsule endoscopic （CE） examination by using M2A capsule endoscope TM （Given Imaging, Yoqneam, Israel） was performed in thirty nine patients （26 males, 13 females） with suspected small intestinal lesions. The composing of the patients was as follows： obscure gastrointestinal bleeding in twenty three patients, known Crohn＇s disease in 6 patients, in whom CE was used to evaluate the severity and extension of the diseases, chronic diarrhea in 8 patients, abdominal pain in one patient and malignancy in one patient with unknown origin. RESULTS： In two patients CE failed. Different abnormalities were revealed in 26 patients overall. Detection rate of abnormalities was highest among patients with obscure gastrointestinal bleeding and the source of bleeding was demonstrated in 17 of 23 patients with obscure bleeding （73.9%）. Entero-Behcet was diagnosed in two patients by CE as a source of obscure gastrointestinal bleeding. In 6 patients with known Crohn＇s disease, CE revealed better evaluation of the disease extension. In 3 of 8 （37.5%） patients with chronic diarrhea; CE revealed some mucosal abnormalities as the cause of chronic diarrhea. In a patient with unexplained abdominal pain and in a cancer patient with unknown origin, CE examination was normal. CONCLUSION： In our relatively small series, we found that capsule endoscopy is a useful diagnostic tool particularly in diagnosis of obscure gastrointestinal bleeding, chronic diarrhea and in estimating the extension of Crohn＇s disease. 展开更多
关键词 Capsule endoscopy Obscure gastrointestinalbleeding Crohn＇s disease Behcet＇s disease
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Role of videocapsule endoscopy for gastrointestinal bleeding 认领 引用 被引量：13
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作者 Cristina Carretero Ignacio Fernandez-Urien +1 位作者 Maite Betes Miguel Muoz-Navas 《World Journal of Gastroenterology》 SCIE CAS 2008年第34期5261-5264,共4页
Obscure gastrointestinal bleeding (OGIB) is defi ned as bleeding of an unknown origin that persists or recurs after negative initial upper and lower endoscopies. Several techniques, such as endoscopy, arteriography, s... Obscure gastrointestinal bleeding (OGIB) is defi ned as bleeding of an unknown origin that persists or recurs after negative initial upper and lower endoscopies. Several techniques, such as endoscopy, arteriography, scintigraphy and barium radiology are helpful for recognizing the bleeding source; nevertheless, in about 5%-10% of cases the bleeding lesion cannot be determined. The development of videocapsule endoscopy (VCE) has permitted a direct visualization of the small intestine mucosa. We will analyze those techniques in more detail. The diagnostic yield of CE for OGIB varies from 38% to 93%, being in the higher range in those cases with obscure-overt bleeding. 展开更多
关键词 Capsule endoscopy Bleeding Small bowel Obscure Hemorrhage
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Diagnosis and therapeutic strategies for small bowel vascular lesions 认领 引用 被引量：15
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作者 Eiji Sakai Ken Ohata +1 位作者 Atsushi Nakajima Nobuyuki Matsuhashi 《World Journal of Gastroenterology》 SCIE CAS 2019年第22期2720-2733,共14页
Small bowel vascular lesions, including angioectasia (AE), Dieulafoy’s lesion (DL) and arteriovenous malformation (AVM), are the most common causes of obscure gastrointestinal bleeding. Since AE are considered to be ... Small bowel vascular lesions, including angioectasia (AE), Dieulafoy’s lesion (DL) and arteriovenous malformation (AVM), are the most common causes of obscure gastrointestinal bleeding. Since AE are considered to be venous lesions, they usually manifest as a chronic, well-compensated condition. Subsequent to video capsule endoscopy, deep enteroscopy can be applied to control active bleeding or to improve anemia necessitating blood transfusion. Despite the initial treatment efficacy of argon plasma coagulation (APC), many patients experience re-bleeding, probably because of recurrent or missed AEs. Pharmacological treatments can be considered for patients who have not responded well to other types of treatment or in whom endoscopy is contraindicated. Meanwhile, a conservative approach with iron supplementation remains an option for patients with mild anemia. DL and AVM are considered to be arterial lesions;therefore, these lesions frequently cause acute life-threatening hemorrhage. Mechanical hemostasis using endoclips is recommended to treat DLs, considering the high re-bleeding rate after primary APC cauterization. Meanwhile, most small bowel AVMs are large and susceptible to re-bleeding therefore, they usually require surgical resection. To achieve optimal diagnostic and therapeutic approaches for each type of small bowel lesion, the differences in their epidemiology, pathology and clinical presentation must be understood. 展开更多
关键词 Angiodysplasia Angioectasia Dieulafoy's lesion Arteriovenous malformation Obscure gastrointestinal bleeding Video capsule endoscopy Deep enteroscopy Argon plasm coagulation
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Small-bowel mucosal injuries in low-dose aspirin users with obscure gastrointestinal bleeding 认领 引用 被引量：13
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作者 Junichi Iwamoto Yuji Mizokami +4 位作者 Yoshifumi Saito Koichi Shimokobe Akira Honda Tadashi Ikegami Yasushi Matsuzaki 《World Journal of Gastroenterology》 SCIE CAS 2014年第36期13133-13138,共6页
AIM: To investigate the clinical differences between small intestinal injuries in low-dose aspirin (LDA) users and in non-steroidal anti-inflammatory drug (NSAID) users who were examined by capsule endoscopy (CE) for ... AIM: To investigate the clinical differences between small intestinal injuries in low-dose aspirin (LDA) users and in non-steroidal anti-inflammatory drug (NSAID) users who were examined by capsule endoscopy (CE) for obscure gastrointestinal bleeding (OGIB). 展开更多
关键词 Non-steroidal anti-inflammatory drugs Low-dose aspirin Small-bowel mucosal injuries Obscure gastrointestinal bleeding Capsule endoscopy
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Wireless capsule endoscopy in the investigation of patients with chronic renal failure and obscure gastrointestinal bleeding (preliminary data) 认领 引用 被引量：10
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作者 Stephanos Karagiannis Spyros Goulas +5 位作者 Georgios Kosmadakis Petros Galanis Dimitrios Arvanitis John Boletis Evangelos Georgiou Christos Mavrogiannis 《World Journal of Gastroenterology》 SCIE CAS 2006年第32期5182-5185,共4页
AIM： To investigate the role of wireless capsule endoscopy （WCE） in detection of small bowel （SB） pathology in patients with chronic renal failure （CRF） and obscure bleeding. METHODS： Consecutive CRF patients ... AIM： To investigate the role of wireless capsule endoscopy （WCE） in detection of small bowel （SB） pathology in patients with chronic renal failure （CRF） and obscure bleeding. METHODS： Consecutive CRF patients with obscure bleeding were prospectively studied. Patients with normal renal function and obscure bleeding, investigated during the same period with WCE, were used for the interpretation of results. RESULTS： Seventeen CRF patients （11 overt, 6 occult bleeding） and 51 patients （33 overt, 18 occult bleeding） with normal renal function were enrolled in this study. Positive SB findings were detected in 70.6% of CRF patients and in 41.2% of non-CRF patients （P〈0.05）. SB angiodysplasia was identified in 47% of CRF patients and in 17.6% of non-CRF patients. Univariate logistic regression revealed CRF as a significant predictive factor for angiodysplasia （P〈0.05）. Therapeutic measures were undertaken in 66% of the patients with the positive findings. CONCLUSION： According to our preliminary results, SB angiodysplasia was found in an increased prevalence among CRF patients with obscure bleeding. WCE is useful in diagnosis of gastrointestinal pathologies and in planning appropriate therapeutic intervention and, therefore, should be included in the work-up of this group of patients. 展开更多
关键词 Chronic renal failure Obscure gastrointestinalbleeding Wireless capsule endoscopy Angiodysplasia
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Different roles of capsule endoscopy and double-balloon enteroscopy in obscure small intestinal diseases 认领 引用 被引量：14
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作者 Zhi-Hong Zhang Chun-Hua Qiu Yi Li 《World Journal of Gastroenterology》 SCIE CAS 2015年第23期7297-7304,共8页
AIM: To compare the roles of capsule endoscopy(CE)and double-balloon enteroscopy(DBE) in the diagnosis of obscure small bowel diseases.METHODS: From June 2009 to December 2014, 88 patients were included in this study;... AIM: To compare the roles of capsule endoscopy(CE)and double-balloon enteroscopy(DBE) in the diagnosis of obscure small bowel diseases.METHODS: From June 2009 to December 2014, 88 patients were included in this study; the patients had undergone gastroscopy, colonoscopy, radiological small intestinal barium meal, abdominal computed tomography or magnetic resonance imaging scan and mesenteric angiography, but their diagnoses were still unclear. The patients with gastrointestinal obstructions,fistulas, strictures, or cardiac pacemakers, as well as pregnant women, and individuals who could not accept the capsule-retention or capsule-removal surgery were excluded. Patients with heart, lung and other vital organ failure diseases were also excluded. Everyone involved in this study had undergone CE and DBE. The results were divided into:(1) the definite diagnosis(the diagnosis was confirmed at least by one of the biopsy,surgery, pathology or the drug treatment effects with follow-up for at least 3 mo);(2) the possible diagnosis(a possible diagnosis was suggested by CE or DBE,but not confirmed by the biopsy, surgery or follow-up drug treatment effects); and(3) the unclear diagnosis(no exact causes were provided by CE and DBE for the disease). The detection rate and the diagnostic yield of the two methods were compared. The differencein the etiologies between CE and DBE was estimated,and the different possible etiologies caused by the age groups were also investigated.RESULTS: CE exhibited a better trend than DBE for diagnosing scattered small ulcers(P = 0.242, Fisher's test), and small vascular malformations(χ 2 = 1.810,P = 0.179, Pearson χ 2 test), but with no significant differences, possible due to few cases. However,DBE was better than CE for larger tumors(P =0.018, Fisher's test) and for diverticular lesions with bleeding ulcers(P = 0.005, Fisher's test). All three hemangioma cases diagnosed by DBE in this study(including sponge hemangioma, venous hemangioma,and hemangioma with hamartoma lesions) were all confirmed by biopsy. Two parasite cases were found by CE, but were negative by DBE. This study revealed no obvious differences in the detection rates(DR) of CE(60.0%, 53/88) and DBE(59.1%, 52/88). However,the etiological diagnostic yield(DY) difference was apparent. The CE diagnostic yield was 42.0%(37/88),and the DBE diagnostic yield was 51.1%(45/88).Furthermore, there were differences among the age groups(χ 2 = 22.146, P = 0.008, Kruskal Wallis Test). Small intestinal cancer(5/6 cases), vascular malformations(22/29 cases), and active bleeding(3/4cases) appeared more commonly in the patients over50 years old, but diverticula with bleeding ulcers were usually found in the 15-25-year group(4/7cases). The over-25-year group accounted for the stromal tumors(10/12 cases).CONCLUSION: CE and DBE each have their own advantages and disadvantages. The appropriate choice depends on the patient's age, tolerance, and clinical manifestations. Sometimes CE followed by DBE is necessary. 展开更多
关键词 Capsule endoscopy Double-balloon enteroscopy Obscure small intestinal diseases
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Emergent single-balloon enteroscopy for overt bleeding of small intestinal vascular malformation 认领 引用 被引量：10
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作者 Chen-Shuan Chung Kuan-Chih Chen +1 位作者 Yueh-Hung Chou Kuo-Hsin Chen 《World Journal of Gastroenterology》 SCIE CAS 2018年第1期157-160,共4页
A 28-year-old man presented with anemia symptoms and intermittent tarry stool passage for three days. No stigmata of hemorrhage were identified using esophagogastroduodenoscopy, ileocolonoscopy, and contrast-enhanced ... A 28-year-old man presented with anemia symptoms and intermittent tarry stool passage for three days. No stigmata of hemorrhage were identified using esophagogastroduodenoscopy, ileocolonoscopy, and contrast-enhanced computed tomography. He then developed massive tarry stool passage with profound hypovolemic shock and hypoxic respiratory failure. Emergent angiography revealed active bleeder, probably from the jejunal branches of the superior mesenteric artery, but embolization was not performed due to possible subsequent extensive bowel ischemia. His airway was secured via endotracheal intubation with ventilator support, and emergent antegrade singleballoon enteroscopy was performed at 8 h after clinical overt bleeding occurrence; the procedure revealed a 2-cm pulsating subepithelial tumor with a protrudingblood plug at the distal jejunum. Laparoscopic segmental resection of the jejunum with end-to-end anastomosis was performed after emergent endoscopic tattooing localization. Pathological examination revealed a vascular malformation in the submucosa with an organizing thrombus. He was uneventfully discharged 5 d later. This case report highlights the benefit of early deep enteroscopy for the treatment of small intestinal bleeding. 展开更多
关键词 Early endoscopy Small intestine Deep enteroscopy Device-assisted enteroscopy Obscure gastrointestinal bleeding Vascular malformation
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Capsule endoscopy in neoplastic diseases 认领 引用 被引量：17
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作者 Marco Pennazio Emanuele Rondonotti Roberto de Franchis 《World Journal of Gastroenterology》 SCIE CAS 2008年第34期5245-5253,共9页
Until recently, diagnosis and management of small-bowel tumors were delayed by the diffi culty of access to the small bowel and the poor diagnostic capabilities of the available diagnostic techniques. An array of new ... Until recently, diagnosis and management of small-bowel tumors were delayed by the diffi culty of access to the small bowel and the poor diagnostic capabilities of the available diagnostic techniques. An array of new methods has recently been developed, increasing the possibility of detecting these tumors at an earlier stage. Capsule endoscopy (CE) appears to be an ideal tool to recognize the presence of neoplastic lesions along this organ, since it is non-invasive and enables the entire small bowel to be visualized. High- quality images of the small-bowel mucosa may be captured and small and ? at lesions recognized, without exposure to radiation. Recent studies on a large population of patients undergoing CE have reported small-bowel tumor frequency only slightly above that reported in previous surgical series (range, 1.6%-2.4%) and have also confirmed that the main clinical indication to CE in patients with small-bowel tumors is obscure gastrointestinal (GI) bleeding. The majority of tumors identified by CE are malignant; many were unsuspected and not found by other methods. However, it remains difficult to identify pathology and tumor type based on the lesion’s endoscopic appearance. Despite its limitations, CE provides crucial information leading in most cases to changes in subsequent patient management. Whether the use of CE in combination with other new diagnostic (MRI or multidetector CT enterography) and therapeutic (Push- and-pull enteroscopy) techniques will lead to earlier diagnosis and treatment of these neoplasms, ultimately resulting in a survival advantage and in cost savings,remains to be determined through carefully-designed studies. 展开更多
关键词 Capsule endoscopy Enteroscopy Obscure gastrointestinal bleeding Small-bowel tumors Polyposis syndromes
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