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Mitochondrial heterogeneity:subpopulations with distinct metabolic activities 认领 引用
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作者 Fabian den Brave Swadha Mishra Thomas Becker 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2025年第3期1102-1103,共2页
In a recent study published in Nature,Ryu et al.1demonstrate the presence of metabolically distinct mitochondrial subpopulations within one cell.One mitochondrial subpopulation contains the FiFo-ATP synthase for oxida... In a recent study published in Nature,Ryu et al.1demonstrate the presence of metabolically distinct mitochondrial subpopulations within one cell.One mitochondrial subpopulation contains the FiFo-ATP synthase for oxidative phosphorylation(OXPHOS),while a second population performs reductive biosynthesis of proline and ornithine.The separation of mitochondria into two functionally distinct pools is reversible and depends on their fusion and fission. 展开更多
关键词 oxidative phosphorylation oxphos metabolically distinct mitochondrial subpopulations functionally distinct pools proline ornithinethe reductive biosynthesis fusion fission oxidative phosphorylation mitochondrial heterogeneity
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