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Pulmonary hypertension in patients with obstructive sleep apnea:Correlation with disease severity and quality of life 认领 引用
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作者 Praveen Kumar Ajay Kumar Verma +10 位作者 Jyoti Bajpai Sujita Kumar Kar Akshyaya Pradhan Surya Kant RajivGarg Santosh Kumar Ram Avadh Singh Kushwaha Sanjeev Kumar Verma Darshan Kumar Bajaj AnandSrivastava Ankit Katiyar 《World Journal of Cardiology》 2026年第1期155-162,共8页
BACKGROUND Obstructive sleep apnea(OSA)is increasingly recognized as a contributor to cardiovascular morbidity,including pulmonary hypertension(PH).AIM To assess the prevalence and severity of PH in newly diagnosed OS... BACKGROUND Obstructive sleep apnea(OSA)is increasingly recognized as a contributor to cardiovascular morbidity,including pulmonary hypertension(PH).AIM To assess the prevalence and severity of PH in newly diagnosed OSA patients and evaluate its association with disease severity and quality of life(QoL).METHODS In this cross-sectional study,113 patients newly diagnosed with OSA underwent echocardiography to assess pulmonary artery pressures and completed the World Health Organisation Quality of Life Brief Version(WHOQOL-BREF)questionnaire.OSA severity was determined via polysomnography using the apneahypopnea index(AHI).Statistical correlations between AHI,right ventricular systolic pressure(RVSP),mean pulmonary artery pressure(MPAP),and QoL domains were analyzed.RESULTS PH(defined by MPAP≥20 mmHg)was observed in 71.68%of patients(MPAP≥20 mmHg).Its prevalence increased with age and OSA severity(P<0.01).The mean RVSP(39.4 mmHg in males vs 34.1 mmHg in females)and MPAP(27.76 mmHg in males vs 24.64 mmHg in females)values were slightly higher in males but the difference was not statistically significant.AHI and oxygen desaturation index positively correlated with RVSP(r=0.677)and MPAP(r=0.543).The WHOQOL-BREF scores were significantly lower in PH patients,particularly in physical and psychological domains(P<0.01).CONCLUSION PH in OSA is strongly linked to disease severity,impairs right ventricular function,and reduces QoL.Findings are limited by the cross-sectional design and reliance on echocardiography instead of right heart catheterization. 展开更多
关键词 Apnea-hypopnea index Obstructive sleep apnea Pulmonary hypertension Quality of life World Health Organization Quality of Life Brief Version
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Association between self-compassion,meaning in life,resilience,health-related quality of life and diabetes self-management among people living with type 2 diabetes in Nigeria 认领 引用
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作者 Chinenye Joseph Aliche Erhabor Sunday Idemudia Ike E.Onyishi 《Journal of Psychology in Africa》 2026年第1期107-115,共9页
Self-compassion is an important psychological resource that improves health-related quality of life and diabetes self-management;however,the psychological processes underlying these associations remain unclear.This st... Self-compassion is an important psychological resource that improves health-related quality of life and diabetes self-management;however,the psychological processes underlying these associations remain unclear.This study examined the roles of meaning in life and resilience in the relationship between self-compassion and both health-related quality of life and diabetes self-management.Participants were 301 individuals living with type 2 diabetes(176(58.5%)females,M age=49.69,SD=12.36)conveniently selected from two tertiary healthcare institutions in Nigeria.They completed self-report measures of self-compassion,meaning in life,resilience,health-related quality of life and diabetes selfmanagement.Multiple regression analyses indicated that self-compassion positively predicted health-related quality of life and diabetes self-management.Meaning in life and resilience independently and positively predicted health-related quality of life and diabetes self-management.Mediation analysis showed that meaning in life mediated the association between self-compassion and health-related quality of life,as well as diabetes self-management.Likewise,resilience mediated the connection between self-compassion and health-related quality of life,and diabetes self-management behaviour.Intervention for diabetes self-management should focus on promoting self-compassion,meaning in life and resilience abilities of patients,as they can potentially improve health and self-care behaviours needed for recovery. 展开更多
关键词 Diabetes self-compassion resilience meaning in life health-related quality of life and diabetes selfmanagement
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Anxiety and depression in relation to resilience and quality of life in patients with kidney calculi 认领 引用
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作者 Da-Wei Luo Hai-Liang Du 《World Journal of Psychiatry》 SCIE 2026年第3期220-228,共9页
BACKGROUND Anxiety and depression are understudied in kidney calculi despite their inverse cor-relation with clinical outcomes.AIM To investigate the correlation of anxiety and depression with resilience and quality o... BACKGROUND Anxiety and depression are understudied in kidney calculi despite their inverse cor-relation with clinical outcomes.AIM To investigate the correlation of anxiety and depression with resilience and quality of life(QoL)in patients with kidney calculi,and to identify contributors to these emotional disorders in such patients.METHODS This study included 119 patients with kidney calculi who visited the First Affiliated Hospital of Xi’an Jiaotong University from May 2022 to March 2025.Patients’anxiety[Hamilton Self-Rating Anxiety Scale(HAMA)],depression[Hamilton Self-Rating Depression Scale(HAMD)],resilience[Connor-Davidson Resilience Scale(CD-RISC)],and QoL[General QoL Inventory-74(GQOLI-74)]were assessed.Spearman correlation coefficients were calculated to analyze the correlations of anxiety and depression with resilience and QoL.Multivariate modeling identified anxiety and depression contributors in patients with kidney calculi.RESULTS Anxiety and depressive symptoms affected 49.58%and 64.71%of participants,respectively.Notably lower CD-RISC scores(across tenacity,strength,and optimism dimensions and the global scale)were observed in the anxiety/depression groups vs their corresponding non-anxietyon-depression groups.The same pattern was observed in GQOLI-74 global and subscale scores.Both HAMA and HAMD correlated inversely with CD-RISC(HAMA:r=-0.194,P=0.034;HAMD:r=-0.413,P<0.001)and GQOLI-74(HAMA:r=-0.394,P<0.001;HAMD:r=-0.347,P<0.001).As confirmed by multivariate regression,per capita monthly income[odds ratio(OR)=0.158,P=0.002],complications(risk factor,OR=3.442,P=0.032),CD-RISC(OR=0.075,P<0.001),and GQOLI-74(OR=0.081,P<0.001)each independently affected anxiety risk.Depression-associated independent predictors included income(OR=0.090,P<0.001),social support(OR=0.136,P=0.003),CD-RISC(OR=0.060,P<0.001),and GQOLI-74(OR=0.198,P=0.023).CONCLUSION Anxiety and depression exhibited an intimate connection with resilience and QoL in patients with kidney calculi.High income,great resilience,and superior QoL are protective against psychological distress. 展开更多
关键词 Kidney calculi Anxiety Depression Resilience Quality of life Determinants
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One-anastomosis gastric bypass vs sleeve gastrectomy for complications,perioperative status,and quality of life:Meta-analysis 认领 引用
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作者 Hyder Osman Mirghani 《World Journal of Gastrointestinal Surgery》 SCIE 2026年第1期358-375,共18页
BACKGROUND One-anastomosis gastric bypass(OAGB)and sleeve gastrectomy(SG)are safe and effective bariatric surgeries.Literature assessing the complications,mortality,operative time/minutes,hospital stay/days,gastroesop... BACKGROUND One-anastomosis gastric bypass(OAGB)and sleeve gastrectomy(SG)are safe and effective bariatric surgeries.Literature assessing the complications,mortality,operative time/minutes,hospital stay/days,gastroesophageal reflux(GORD),malnutrition,and quality of life is scarce.AIM To compare OAGB and SG regarding the above outcomes.METHODS We searched 4 databases from inception up to July 2025.The keywords bariatric surgery,metabolic surgery,gastric bypass,SG,complications,perioperative,quality of life,operative time,hospital stay,GORD,malnutrition,and mortality were used.Out of 1163 studies retrieved,54 full texts were reviewed,and 31 studies were included in the meta-analysis.RESULTS No significant differences were evident between OAGB and SG regarding complications,odds ratio(OR),1.37,95%confidence interval(CI):0.78-2.41.Operative time/minutes,hospital stay/days,and quality of life were similar between the two procedures,mean differences,2.55,95%CI:3.61-8.70;-0.55,95%CI:-1.12 to 0.02;and-0.37,95%CI:-1.18 to 0.43 respectively,in sub-analyses including superobesity and high diabetes,no significant differences were found regarding complications rate and operative time with higher hospital stay in patients with diabetes.Mortality and GORD were higher in SG,OR,4.70,95%CI:1.64-13.52,and OR,3.23,95%CI:1.56-6.72,while malnutrition was more common in OAGB,OR,0.46,95%CI:0.36-0.59.CONCLUSION There were no differences between OAGB and SG regarding complications,mortality,operation time/minutes,hospital stay/days,and quality of life.Mortality and GORD were higher in SG,while malnutrition was higher in OAGB.Further well-controlled trials comparing OAGB and SG regarding long-term outcomes are needed. 展开更多
关键词 One anastomosis gastric bypass Sleeve gastrectomy Complications Quality of life Operative time Mortality Hospital stay
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Prediction model for quality of life in sepsis survivors one year after discharge 认领 引用 被引量：1
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作者 Yi Yao Wenjin Li +3 位作者 Dejiang Hong Ze Chen Kai Peng Guangju Zhao 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2026年第2期105-112,共8页
BACKGROUND:Sepsis survivors experience poor long-term quality of life post-discharge.The aim of this study was to analyze the factors that impact the long-term quality of life of sepsis survivors and develop a clinica... BACKGROUND:Sepsis survivors experience poor long-term quality of life post-discharge.The aim of this study was to analyze the factors that impact the long-term quality of life of sepsis survivors and develop a clinical prediction model.METHODS:A total of 442 sepsis patients from the Emergency Intensive Care Unit of a tertiary hospital in Wenzhou were included.These patients were assigned to the training set or the validation set at a ratio of 7:3.The European Quality of Life 5 Dimensions 5 Level Version(EQ-5D-5L) questionnaire was used to evaluate the quality of life in sepsis survivors one year after discharge.Multivariate logistic regression analysis was used to identify predictors,which were then used to develop the prediction model and subsequently derive a scoring system.The model's effectiveness was assessed using an area under the receiver operating characteristic curve,calibration curves,and clinical decision analysis.RESULTS:Of the 442 patients included,70 died one year after discharge,and 372 completed the questionnaire.A total of 46.6% of sepsis survivors have poor quality of life one year after discharge in the training set.Multivariate logistic regression revealed that age,platelet,serum albumin,serum urea,and C-reactive protein were independent risk factors for poor quality of life in sepsis survivors.The area under the curve of the scoring system was 0.777(95% CI:0.726–0.828).The calibration curves showed that it was well calibrated.Decision curve analysis indicated that the scoring system provided good clinical usefulness.The internal validation also demonstrated its effectiveness.CONCLUSION:The prediction model incorporating five risk factors may predict quality of life one year after discharge in sepsis survivors,which provides a measure to develop post-discharge rehabilitation and follow-up plans for this patient population. 展开更多
关键词 Sepsis Sepsis survivors Quality of life EQ-5D-5L Prediction model
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Psychological burden of bone and joint infections:Systematic review on mental health and quality of life implications 认领 引用
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作者 Daniele De Meo Tommaso Accinni +5 位作者 Davide Staccini Flavia Petrucci Paolo Martini Vittorio Candela Carmine Zoccali Stefano Gumina 《World Journal of Orthopedics》 2026年第3期113-122,共10页
BACKGROUND Bone and joint infections(BJIs),such as periprosthetic joint infections and fracture-related infections,are severe complications in orthopedic surgery with profound physical,social,and psychological consequ... BACKGROUND Bone and joint infections(BJIs),such as periprosthetic joint infections and fracture-related infections,are severe complications in orthopedic surgery with profound physical,social,and psychological consequences.While their physical and economic impacts are well documented,the psychological burden remains underrecognized.AIM To systematically review the existing literature on the impact of BJIs on mental health and quality of life,and to identify validated tools used to assess these outcomes.METHODS Systematic review was conducted on PubMed and Scopus database.Seventeen studies published between 2010 and 2024 were included(5 qualitative,12 quantitative).RESULTS Qualitative findings revealed consistent emotional suffering,including fear,helplessness,depression,and social withdrawal,especially during the interim phase of two-stage revisions.Quantitative studies confirmed a significant deterioration in mental health,even after clinical resolution of the infection.Among the tools employed,the International Classification of Diseases-10-Symptom Rating and the Hospital Anxiety and Depression Scale emerged as the most sensitive for detecting psychological distress.CONCLUSION Despite growing awareness,there is still a lack of specific psychological interventions and standardized assessment protocols for this vulnerable patient population.These findings underscore the urgent need for integrating mental health evaluation and support into comprehensive BJI treatment strategies to improve outcomes and long-term quality of life. 展开更多
关键词 Mental health Bone infection Periprosthetic joint infection Fracture related infection Anxiety Depression Quality of life Psychopathology
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Significant quality of life improvement following total knee replacement for end-stage osteoarthritis:Retrospective cohort study 认领 引用
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作者 Mohammed H Abushal Osama M Embaby +2 位作者 Mahmoud Mersal Emran Badghish Mohamed Elalfy 《World Journal of Orthopedics》 2026年第3期64-70,共7页
BACKGROUND Total knee replacement(TKR)is a cornerstone intervention for advanced knee osteoarthritis(OA),yet real-world data directly comparing its impact on healthrelated quality of life(HRQoL)against non-surgical ma... BACKGROUND Total knee replacement(TKR)is a cornerstone intervention for advanced knee osteoarthritis(OA),yet real-world data directly comparing its impact on healthrelated quality of life(HRQoL)against non-surgical management using standardized patient-reported outcome measures remains limited,particularly from the Middle East.This study addresses this gap by evaluating HRQoL changes in a Saudi Arabian cohort.AIM To compare the change in HRQoL,measured by the EuroQol five-dimension,fivelevel questionnaire(EQ-5D-5 L)instrument,between patients undergoing TKR and those receiving conservative treatment for severe knee OA.METHODS This retrospective cohort study was conducted at a tertiary orthopedic center in Saudi Arabia,analyzing data from patients with Kellgren-Lawrence grade III-IV knee OA between January 2018 and December 2022.This study is reported following the STROBE guidelines.Patients were allocated into two groups:The TKR group(n=480)and the conservative management group(n=400).The primary outcome was the change in the EQ-5D-5 L index score from baseline to one-year post-intervention.Statistical analyses included paired and independent t-tests,with a P value<0.05 considered significant.RESULTS A total of 880 patients were included in the final analysis.The TKR group demonstrated a substantial and clinically significant improvement in mean EQ-5D-5 L scores,from 0.35±0.08 at baseline to 0.76±0.09 at one year(mean change:+0.41;95%confidence interval:0.39-0.43;P<0.001).This improvement far exceeded the minimal clinically important difference of 0.07-0.12.In contrast,the conservative management group showed a minimal,nonsignificant improvement from 0.36±0.07 to 0.42±0.08(mean change:+0.06;95%confidence interval:0.04-0.08;P=0.07),which did not meet the minimal clinically important difference.The between-group difference in HRQoL improvement was statistically significant(P<0.001).CONCLUSION This study provides strong evidence that TKR leads to substantial and clinically meaningful improvements in HRQoL for patients with severe knee OA,whereas conservative management offers limited benefits.These findings reinforce the effectiveness of TKR in the management of advanced OA,support timely surgical referral,and validate the use of the EQ-5D-5 L as a robust patient-reported outcome measure in this patient population. 展开更多
关键词 Total knee replacement Knee osteoarthritis Health-related quality of life Patient-reported outcome measures Conservative management Retrospective cohort study
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Anxiety,depression,and quality of life in hepatocellular carcinoma treated with drug-eluting microspheres plus lenvatinib:A prospective study 认领 引用
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作者 Jian-Yu Liu Zhi-Hui Liang +3 位作者 Jing-Lei Liu Liang Li Bao Cui Tie-Gang Li 《World Journal of Psychiatry》 SCIE 2026年第4期369-381,共13页
BACKGROUND Patients with hepatocellular carcinoma(HCC)often experience considerable psychological distress that affects their quality of life(QoL).AIM To investigate the effects of drug-eluting microsphere-transcathet... BACKGROUND Patients with hepatocellular carcinoma(HCC)often experience considerable psychological distress that affects their quality of life(QoL).AIM To investigate the effects of drug-eluting microsphere-transcatheter arterial chemoembolization(DEM-TACE)combined with lenvatinib on anxiety,depression,and QoL.METHODS This prospective study enrolled 126 patients with primary HCC treated with DEM-TACE combined with lenvatinib from October 2022 to October 2025.Anxiety and depression assessment with the Hospital Anxiety and Depression Scale(HADS)and QoL evaluation with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30(EORTC QLQC30)and HCC-specific module were conducted at baseline and at 3-,6-,and 12-month.Clinical outcomes,including overall survival,progression-free survival,and adverse events(AEs),were recorded.RESULTS Overall,58.7%and 61.1%of patients exhibited anxiety and depression at baseline,respectively.After treatment,both psychological status and QoL significantly improved.At 12 months,the prevalence rates of anxiety and depression decreased to 31.0%and 28.6%,respectively(both P<0.001).The EORTC QLQ-C30 global health status score increased from 52.3±15.7 to 71.2±14.3(P<0.001).Physical,role,and emotional functioning scores also significantly improved(all P<0.001).Treatment-related AEs were generally manageable.Multivariate analysis showed that baseline HADS score,Barcelona Clinic Liver Cancer stage,and tumor response were independent predictors of QoL outcomes(P<0.05).CONCLUSION DEM-TACE combined with lenvatinib shows an acceptable safety profile and favorable efficacy in improving anxiety,depression,and QoL in patients with HCC.Early psychological assessment and intervention may optimize outcomes. 展开更多
关键词 Anxiety Depression Drug-eluting microspheres Hepatocellular carcinoma Lenvatinib Quality of life
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Beyond survival:Pain as the main determinant of long-term quality of life after thoracic trauma surgery 认领 引用
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作者 Federico Raveglia Sara Degiovanni +12 位作者 Luca Bertolaccini Andrea Cara Enrico Mario Cassina Federica Danuzzo Lidia Libretti Emanuele Pirondini Maria Chiara Sibilia Francesca Spinelli Antonio Tuoro Matilde De Simone Marco Chiarelli Ugo Cioffi Francesco Petrella 《World Journal of Clinical Cases》 2026年第13期10-18,共9页
BACKGROUND Thoracic trauma is a major cause of trauma-related morbidity and mortality,often resulting from blunt mechanisms.While advances in acute management have improved short-term outcomes,long-term results-partic... BACKGROUND Thoracic trauma is a major cause of trauma-related morbidity and mortality,often resulting from blunt mechanisms.While advances in acute management have improved short-term outcomes,long-term results-particularly health-related quality of life(QoL)after chest wall surgery-remain poorly defined.Identifying factors influencing long-term QoL is essential to optimize patient care.AIM To investigate long-term QoL and identify clinical factors influencing outcomes.METHODS Forty-one consecutive patients underwent chest wall surgery for thoracic trauma between November 2016 and November 2024 at our Hospital.Data collected for this retrospective cohort study included demographics,trauma characteristics,surgical details,postoperative complications,hospital and intensive care unit stay,and long-term patient-reported outcomes[EuroQol 5-Dimension 3-Level Questionnaire(EQ-5D-3 L),Numerical Rating Scale(NRS)for pain,and dyspnea scores].Univariable and multivariable linear regression analyses were performed to identify predictors of QoL and pain.RESULTS At a median follow-up of 14 months(range 1-72),the median EQ-5D-3 L score was 0.68(range 0.027-1),with no significant correlation with follow-up duration(Spearman’s rho=-0.05,P=0.78).Pain was the only independent predictor of lower QoL(β=-0.079 per NRS unit,P=0.016).Age,male gender,and comorbidities showed nonsignificant negative trends with QoL.For pain,a greater number of comorbidities was significantly associated with lower pain scores(β=-0.810,P=0.041),while male sex was non-significantly associated with less pain.Dyspnea and perioperative variables were not significantly related to either outcome.CONCLUSION Long-term QoL after chest wall surgery is lower than the general population;pain is the main determinant.Effective pain control and comorbidity management are essential for personalized postoperative care. 展开更多
关键词 Quality of life Chest trauma Rib fixation Surgery Age Pain EuroQol 5-Dimension 3-Level Questionnaire
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Analysis of quality of life and reflux oesophagitis following Billroth Ⅱ and Roux-en-Y gastrointestinal reconstruction for gastric cancer 认领 引用
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作者 Xin-Xing Duan Xiong Yu Jin Gan 《World Journal of Gastrointestinal Surgery》 SCIE 2026年第1期228-235,共8页
BACKGROUND The choice between Billroth Ⅱ and Roux-en-Y reconstruction after radical gastrectomy for gastric cancer(GC)affects the occurrence of reflux and the quality of life(QoL)in patients.AIM To investigate the Qo... BACKGROUND The choice between Billroth Ⅱ and Roux-en-Y reconstruction after radical gastrectomy for gastric cancer(GC)affects the occurrence of reflux and the quality of life(QoL)in patients.AIM To investigate the QoL and reflux oesophagitis incidence in patients who underwent Billroth Ⅱ or Roux-en-Y gastrointestinal reconstruction after radical gastrectomy for GC.METHODS One hundred patients with GC who underwent radical resection at our hospital between January 2023 and December 2024 were enrolled.The patients were divided into two groups based on the postoperative gastrointestinal reconstruction technique:The Billroth Ⅱ group and the Roux-en-Y group,comprising 50 patients each.The incidence of gastroesophageal reflux within two weeks postoperatively was compared between the groups,including 24-hour reflux episodes,frequency of reflux episodes lasting>5 minutes,and maximum reflux duration.The reflux symptom scores were measured.Nutritional indicators,including serum albumin(ALB),prealbumin(PA),and haemoglobin(Hb),were assessed 4 and 8 weeks postoperatively.The QoL was evaluated using the QLQ-C30 questionnaire.The incidence of reflux oesophagitis was monitored at 3 months of follow-up.RESULTS No significant differences were observed between the groups in terms of baseline clinical characteristics(P>0.05).At 2 weeks postoperatively,the Roux-en-Y group exhibited significantly lower 24-hour reflux episodes,episodes lasting>5 minutes,and maximum reflux duration than the Billroth Ⅱ group(P0.05).The QLQ-C30 scores at 4 and 8 weeks postoperatively were significantly higher in the Roux-en-Y group than in the Billroth Ⅱ group(P<0.05).At the 3-month postoperative follow-up,the incidence of reflux oesophagitis was 4.0%in the Roux-en-Y group,significantly lower than the 16.0%observed in the Billroth Ⅱ group(P<0.05).CONCLUSION Among patients with GC undergoing gastrointestinal reconstruction,Roux-en-Y procedures resulted in fewer cases of gastroesophageal reflux and milder symptoms than Billroth Ⅱ procedures.Nutritional status was comparable postoperatively between the two reconstruction techniques.However,the former significantly affects the patients'QoL less favourably and exhibits a lower incidence of reflux oesophagitis,demonstrating considerable clinical significance. 展开更多
关键词 Gastric cancer Gastrointestinal reconstruction BillrothⅡprocedure Roux-en-Y procedure Quality of life Reflux oesophagitis
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Midwifery-coordinated care:Improving quality of life,maternal satisfaction,and medication adherence in pregnancy-induced hypertension 认领 引用
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作者 Madhusmita NAYAK Pravati TRIPATHY Prasanta Kumar NAYAK 《Journal of Integrative Nursing》 2026年第1期30-37,共8页
Objective:The objective of this study is to evaluate the impact of a midwifery-coordinated care model on quality of life,maternal satisfaction,and medication adherence among women with pregnancy-induced hypertension.M... Objective:The objective of this study is to evaluate the impact of a midwifery-coordinated care model on quality of life,maternal satisfaction,and medication adherence among women with pregnancy-induced hypertension.Materials and Methods:A quasi-experimental,post-test-only control group design was employed.A total of 100 antenatal women diagnosed with pregnancy-induced hypertension(PIH)after 20 weeks of gestation were recruited using convenience sampling from the antenatal OPD and labor room of IMS and SUM Hospital,Bhubaneswar.Participants were equally allocated to an experimental group(n=50)and a control group(n=50).The experimental group received a structured midwifery-coordinated care intervention delivered through five modules at 20-22,28-29,32-33,and 36-37 weeks of gestation,with a final session before delivery,while the control group received routine hospital care.Data were collected using a structured sociodemographic and obstetric pro forma,the Satisfaction of Mothers with Midwifery Care Questionnaire,WHOQOL-BREF,and the Medication Adherence Report Scale.Results:After intervention,the experimental group showed significantly higher maternal satisfaction(t(98)=5.11,P=0.001),quality of life(t(98)=8.31,P=0.001),and medication adherence(t(148)=2.12,P=0.035)compared to the control group,along with significantly lower DBP at 32 weeks(t(148)=4.83,P=0.001)and higher maternal weight at 20 weeks(t(98)=7.44,P=0.013).Conclusion:The midwifery-coordinated care model significantly improved maternal satisfaction,quality of life,and medication adherence among women with PIH,highlighting its potential to enhance maternal and fetal outcomes. 展开更多
关键词 Maternal satisfaction medication adherence midwifery‑coordinated care model pregnancy‑induced hypertension quality of life
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Parallel Mediating Roles of Illness Acceptance Attitudes Between Physical Symptoms and Quality of Life in Patients with Gastrointestinal Cancers 认领 引用
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作者 Yue-jiao Fan Jian-li Hu 《Current Medical Science》 SCIE CAS CSCD 2026年第2期496-505,共10页
Objective Physical symptoms severely impair quality of life(QoL)in patients with gastrointestinal cancers(GICs).Although illness acceptance is recognized as a key mediator,the distinct roles of its two dimensions—act... Objective Physical symptoms severely impair quality of life(QoL)in patients with gastrointestinal cancers(GICs).Although illness acceptance is recognized as a key mediator,the distinct roles of its two dimensions—active acceptance and negative acceptance—remain underexplored in the symptom-QoL pathway.This study aimed to explore their parallel mediating roles.Methods In this cross-sectional study,301 inpatients with GICs completed the MD Anderson Symptom Inventory(MDASI),the 12-item Short Form Health Survey(SF-12),the Illness Cognition Questionnaire-Acceptance subscale(ICQ-A,measuring active acceptance),and the Medical Coping Modes Questionnaire(MCMQ,measuring negative acceptance).Parallel mediation analysis was performed using PROCESS Model 4 with bootstrap resampling(5,000 iterations).Results Symptom severity was negatively correlated with QoL(r=-0.69,P<0.01)and active acceptance(r=-0.47,P<0.01),and positively correlated with negative acceptance(r=0.56,P<0.01).Active acceptance was positively(r=0.60)and negative acceptance negatively(r=-0.60)correlated with QoL(both P<0.01).Mediation analysis revealed two significant indirect pathways:symptoms→reduced active acceptance→lower QoL,accounting for 23.92%of total effect(95%bootstrap CI[−0.068,−0.033]),and symptoms→increased negative acceptance→lower QoL,accounting for 25.36%of total effect(95%bootstrap CI[−0.074,−0.035]).Neither confidence interval contained zero.Conclusion Both active acceptance and negative acceptance independently mediate the relationship between physical symptoms and QoL in patients with GICs.Active acceptance buffers the impact of symptoms,whereas negative acceptance exacerbates it.These findings support integrating psychological interventions that foster active acceptance and mitigate negative acceptance as a core component of symptom management to optimize QoL in this population. 展开更多
关键词 Gastrointestinal cancer Illness acceptance Quality of life Physical symptoms Mediation analysis Psychological adjustment
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Impact of bundle care on quality of life and nutrition after transarterial chemoembolization 认领 引用
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作者 Gui-Yun Zhao Jie Yu 《World Journal of Gastrointestinal Oncology》 SCIE 2026年第6期177-188,共12页
BACKGROUND The absence of standard postoperative protocols for patients with hepatocellular carcinoma(HCC)undergoing transarterial chemoembolization(TACE)may negatively affect health and quality of life(QoL).Bundle ca... BACKGROUND The absence of standard postoperative protocols for patients with hepatocellular carcinoma(HCC)undergoing transarterial chemoembolization(TACE)may negatively affect health and quality of life(QoL).Bundle care is a multidisciplinary,evidence-based model that offers a structured approach.Yet,its effects on this population remain underexplored.The hypothesis in this study was that the implementation of the bundle care protocol can improve QoL and nutritional status after TACE.AIM To examine the effects of a multidisciplinary bundle care protocol on the QoL and nutritional status of post-TACE HCC patients.METHODS A tertiary hospital conducted a retrospective study on 80 HCC patients who underwent TACE from June 2023 to January 2025.They were included in the routine care group(control group;n=40),routine care and bundle care group(intervention group;n=40).The bundle care protocol included multidisciplinary coordination,dynamic assessments[Patient-Generated Subjective Global Assessment(PG-SGA),Hospital Anxiety and Depression Scale(HADS),Numerical Rating Scale],stepwise analgesia,stratified nutrition support,and intelligent follow-up with WeChat.The nutritional status(PG-SGA),psychological scores(HADS),post-embolization symptoms,and laboratory parameters were outcome measures.Independent t-tests,χ2 tests and non-parametric tests were used to analyze data.RESULTS Post-intervention,the bundle care group showed significantly lower PG-SGA scores than the control group(1.86±0.89 vs 4.46±2.13,P<0.001),lower anxiety(HADS-Anxiety:0.36±0.49 vs 4.25±2.03,P<0.001)and depression scores(HADS-Depression:0.00 vs 5.00,P<0.001).Albumin levels(38.33±4.09 g/L vs 35.60±4.87 g/L,P=0.008)and body mass index(24.24±2.45 vs 21.67±2.63,P<0.001)were significantly higher in the bundle care group.Nausea resolution was 97.5%in the bundle care group vs 87.5%in controls(P<0.05).CONCLUSION In patients with HCC after TACE,bundle care can significantly improve nutritional status,psychological status,and symptom control to make a case for further clinical use. 展开更多
关键词 Bundle care Transarterial chemoembolization Hepatocellular carcinoma Nutritional status Quality of life
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Incidence of readmission,mortality,and quality of life in patients with heart failure:a comprehensive assessment at a tertiary care hospital in India 认领 引用
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作者 Mahesh Bhupal Chendake Abhijeet Bhausaheb Shelke Vaishali Rajsinh Mohite 《Frontiers of Nursing》 2026年第1期121-129,共9页
Objective:Heart failure(HF)is a complex clinical syndrome that affects nearly 64 million individuals globally.Frequent hospital readmissions lead to poor health outcomes,impact quality of life(QoL),and are associated ... Objective:Heart failure(HF)is a complex clinical syndrome that affects nearly 64 million individuals globally.Frequent hospital readmissions lead to poor health outcomes,impact quality of life(QoL),and are associated with high mortality rates.This study assessed readmissions,mortality,and QoL outcomes in patients with HF in a tertiary care hospital setting.Methods:Patients aged≥18 years with HF,who visited the tertiary care hospital in Karad,India were included in the study(November2019 to October 2021).Demographics,disease characteristics,and condition at discharge were recorded using the medical records of patients.The quantitative data included readmission rates and mortality rates.The qualitative aspects describing patients'QoL were assessed using a patient-reported 21-question QoL questionnaire.Results:A total of 98 patients,predominantly male(63.3%),with a mean age of 62.9 years were included.The majority of the patients(80.6%)required<15 days of hospitalization.The 2-year readmission rate was 24.4%,while the mortality rate was 43.9%.Self-care pattern showed that patients seemed to be taking mild to average care while taking good care was rare.The QoL data showed that 22.4% were living a good quality life,44.9% average,while 32.7% were living a low-quality life.Better education and better self-care were associated with a low rate of readmission.Conclusions:We were able to assess the incidence of readmission,mortality,and QoL in patients with HF in a tertiary care hospital setting.The study showed that HF impacts patients'physical,emotional,and psychological wellbeing. 展开更多
关键词 heart failure mortality quality of life readmission standard of living
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Psychological burden of hemorrhoidal disease:Association with depression,anxiety,and quality of life impairment 认领 引用
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作者 Bahadır Ondeş Osman G Gökdere +1 位作者 Kerim Uğur Burhan H Kanat 《World Journal of Psychiatry》 SCIE 2026年第7期83-91,共9页
BACKGROUND Hemorrhoidal disease(HD)is one of the most common benign anorectal conditions worldwide.It is typically diagnosed by physical symptoms such as pain,bleeding,pruritus,and discomfort;however,its psychological... BACKGROUND Hemorrhoidal disease(HD)is one of the most common benign anorectal conditions worldwide.It is typically diagnosed by physical symptoms such as pain,bleeding,pruritus,and discomfort;however,its psychological and psychosocial impact is not well understood.Chronic anorectal symptoms often cause psychological distress driven by pain-related anxiety,embarrassment,and social withdrawal.While psychological comorbidities are well-documented in other gastrointestinal conditions,there is limited evidence directly investigating the impact of depression,anxiety,and quality of life(QoL)in patients with HD.AIM To investigate the association between HD and depression,anxiety,and QoL.METHODS This cross-sectional case-control study included 74 patients with grade Ⅰ-Ⅱ HD and 74 age-and sex-matched healthy controls at Malatya Training and Research Hospital.Participants completed the Beck Depression Inventory,Beck Anxiety Inventory,and World Health Organization Quality of Life Instrument-Short Form questionnaire.Group comparisons were performed using parametric or nonparametric tests as appropriate.Spearman correlation and path analysis were used to evaluate the associations between HD and psychological outcomes.RESULTS Patients with HD demonstrated significantly higher depression(11.92±10.48 vs 5.54±4.16)and anxiety(11.76±10.13 vs 6.77±5.07)scores compared with healthy controls(P<0.001 for both).QoL analysis revealed significantly lower scores in the general health,physical,and social domains(P<0.05).No significant differences were observed in the psychological or environmental domains.Correlation analysis demonstrated that HD had a low-to-moderate positive correlation with anxiety and depression,while inversely correlating with specific aspects of QoL.Path analysis confirmed significant direct effects of HD on depression,anxiety,and several QoL domains.CONCLUSION HD is associated with increased depression and anxiety and reduced QoL,highlighting the importance of psychosocial assessment in clinical management. 展开更多
关键词 Hemorrhoidal disease Depression Anxiety Quality of life Psychosocial impact
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Smartphone-based mobile health impact on oral anticoagulation adherence,quality of life,and healthcare utilization in adult atrial fibrillation 认领 引用
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作者 Muhammad Farhan Tirath Patel +9 位作者 Waleed Harazeen Yara Mohamed Abdullah Al Azzawi Heba Intabli Nada Ahmed Mohammed Al-Hadi Naseer Obais Mohammad Riyad Alkhazali Bhumi Daishik Patel Asfaq Ahmad Ayoola Awosika 《World Journal of Methodology》 2026年第3期290-303,共14页
BACKGROUND Atrial fibrillation(AF)is a prevalent arrhythmia associated with increased stroke risk,morbidity,and healthcare burden.Oral anticoagulation(OAC)is essential for stroke prevention,but adherence is often subo... BACKGROUND Atrial fibrillation(AF)is a prevalent arrhythmia associated with increased stroke risk,morbidity,and healthcare burden.Oral anticoagulation(OAC)is essential for stroke prevention,but adherence is often suboptimal.Smartphone-based mobile health(mHealth)applications offer potential to enhance adherence,quality of life(QoL),and reduce healthcare utilization.AIM To systematically review randomized controlled trials(RCTs)evaluating the impact of smartphone-based mHealth interventions on OAC adherence,health-related QoL,and healthcare utilization in adults with AF.METHODS Following PRISMA guidelines and a PROSPERO-registered protocol(CRD420251169904),databases(PubMed,Scopus,Web of Science,EMBASE,Cochrane CENTRAL,CINAHL,ClinicalTrials.gov)were searched from January 1,2000,to July 30,2025.Eligible studies were RCTs of mHealth apps for AF management in adults(≥18 years).Two reviewers screened records,extracted data,and assessed risk of bias using Cochrane risk of bias 2.Narrative synthesis was used due to heterogeneity.RESULTS Of 968 records,16 RCTs(n=209-3324 participants)were included,primarily from China,United States,Taiwan,and South Korea.Integrated interventions(e.g.,mAFA-II aligning with AF better care pathway)improved OAC adherence(e.g.,higher self-reported scores,P<0.05;increased OAC persistence,P<0.001),enhanced QoL(e.g.,EQ-5D improvements,P<0.001),and reduced healthcare utilization(e.g.,rehospitalizations hazard ratio=0.32,P<0.001)without increasing bleeding risks.Simpler apps showed inconsistent benefits.Heterogeneity in designs,adherence measures,and follow-up(3 months to 2 years)limited generalizability.Risk of bias was high in 10 studies due to open-label designs and post-hoc analyses.CONCLUSION mHealth apps,especially comprehensive ones,can improve OAC adherence,QoL,and reduce utilization in AF patients.Future research should focus on long-term efficacy,cost-effectiveness,and equitable implementation for diverse populations. 展开更多
关键词 Atrial fibrillation Mobile health Oral anticoagulation Adherence Quality of life Healthcare utilization Systematic review
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Impact of anxiety and depression on quality of life in gastric cancer patients receiving SOX neoadjuvant chemotherapy 认领 引用
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作者 Bo-Yang Cui Zhen Zhang 《World Journal of Gastrointestinal Oncology》 SCIE 2026年第7期190-199,共10页
BACKGROUND Gastric cancer(GC)is a leading cause of cancer mortality globally.The SOX neoadjuvant chemotherapy regimen is standard for early-to-mid-stage disease,but chemotherapy-related stress often induces psychologi... BACKGROUND Gastric cancer(GC)is a leading cause of cancer mortality globally.The SOX neoadjuvant chemotherapy regimen is standard for early-to-mid-stage disease,but chemotherapy-related stress often induces psychological distress.AIM To investigate the prevalence,risk factors of anxiety and depression in stage II-III GC patients receiving SOX neoadjuvant chemotherapy,and clarify their independent impacts on quality of life(QoL).METHODS A retrospective analysis was conducted on 153 patients with stage II-III GC receiving SOX regimen NACT at The Second Affiliated Hospital of Kunming Medical University Hospital.Anxiety and depression were assessed using the Zung Self-Rating Anxiety(SAS)and Zung Self-Rating Depression Scale(SDS)scales.QoL was evaluated with the QoL Questionnaire Core 30 questionnaire.Demographic,clinical data,and adverse reactions were collected.Multivariate logistic regression identified risk factors for anxiety/depression.Multiple linear regression analyzed the independent impact of psychological distress on global QoL.RESULTS The prevalence of anxiety(SAS≥50)and depression(SDS≥53)was 37.91%(58/153)and 39.87%(61/153),respectively;47.71%(73/153)had either symptom(anxiety-depression group).Independent risk factors for anxiety/depression included female gender[odds ratio(OR)=2.13,95%confidence interval(CI):1.03-4.40],unmarried/divorced/widowed status(OR=3.17,95%CI:1.28-7.85),primary school education or below(OR=3.50,95%CI:1.33-9.21),and clinical stage III(OR=2.69,95%CI:1.32-5.46).The anxiety-depression group had higher Grade III–IV gastrointestinal reactions(20.55%vs 8.75%,P=0.021).SAS/SDS scores negatively correlated with emotional(r=-0.552/-0.599),social(r=-0.403/-0.471),physical functioning(r=-0.369/-0.404),and global QoL(r=-0.539/-0.574,all P<0.001).After adjusting confounders,anxiety(β=-0.12,P=0.013)and depression(β=-0.14,P<0.001)independently predicted lower global QoL.CONCLUSION Anxiety and depression are common in early-to-mid-stage GC patients receiving SOX neoadjuvant chemotherapy,associated with specific demographic/clinical factors,severe gastrointestinal reactions,and poor QoL,highlighting the need for routine psychological screening and intervention. 展开更多
关键词 Anxiety Depression Gastric cancer Neoadjuvant chemotherapy Quality of life
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Failure mode and effects analysis nursing model improves recovery and quality of life post-laparoscopic extended radical colectomy for colorectal cancer 认领 引用 被引量：1
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作者 Qian-Qian Yang Zhen-Kun Wu 《World Journal of Gastrointestinal Surgery》 SCIE 2026年第2期93-104,共12页
BACKGROUND Postoperative gastrointestinal recovery is a critical factor influencing patient rehabilitation.AIM To investigate the effects of conventional care compared with the failure mode and effects analysis(FMEA)p... BACKGROUND Postoperative gastrointestinal recovery is a critical factor influencing patient rehabilitation.AIM To investigate the effects of conventional care compared with the failure mode and effects analysis(FMEA)protocol on postoperative recovery in patients undergoing surgery.METHODS A retrospective cohort study analyzed 225 patients with colorectal cancer(conventional care group:n=122;FMEA group:n=103)treated between June 2021 and June 2024.Outcomes included gastrointestinal recovery(time to flatus/bowel movement and diet tolerance),functional capacity(6-minute walk distance test and sit-to-stand test),complications,quality of life(General Comfort Questionnaire,Barthel index,and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30),and satisfaction.RESULTS The FMEA group demonstrated significantly accelerated recovery:Shorter hospital stays(4.49±0.38 days vs 4.66±0.42 days,P=0.002),earlier flatus(18.58±1.86 hours vs 19.09±1.93 hours,P=0.045),and improved 6-minute walk distance at 8 weeks(526.16±88.71 m vs 495.29±94.82 m,P=0.013).Complication rates decreased(nausea/vomiting:12.62%vs 22.95%,P=0.046;bowel obstruction:2.91%vs 10.66%,P=0.024).Quality of life metrics significantly favored FMEA:Total comfort score(91.66±4.71 vs 89.27±4.87,P<0.001),Barthel index(67.93±3.19 vs 66.71±3.35,P=0.006),and higher“very satisfied”rates(61.17%vs 47.54%,P=0.041).CONCLUSION FMEA-based nursing significantly enhances postoperative functional recovery,reduces complications,and improves quality of life in patients undergoing extended colectomy. 展开更多
关键词 Failure mode and effects analysis Postoperative recovery Functional recovery Gastrointestinal function Postoperative quality of life Nursing intervention
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Psychological intervention and health education effects on quality of life in patients after pancreatic cancer surgery:A meta-analysis 认领 引用
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作者 Xiao-Lan Shi Jia-Ping Chen +3 位作者 He Li Bi-Rong Zhao Dong-Mei Xu Lu-Qing Xu 《World Journal of Gastrointestinal Surgery》 SCIE 2026年第5期352-366,共15页
BACKGROUND Pancreatic cancer is one of the most aggressive malignancies,and surgery remains the only potentially curative treatment.However,postoperative complications,psychological distress,and treatment-related symp... BACKGROUND Pancreatic cancer is one of the most aggressive malignancies,and surgery remains the only potentially curative treatment.However,postoperative complications,psychological distress,and treatment-related symptoms can severely impair quality of life(QoL)of patients.Although psychological interventions and health education have shown beneficial effects in other cancer populations,their effectiveness in postoperative patients with pancreatic cancer remains inconsistent and inadequately synthesized.We hypothesized that structured psychological and educational support would improve global health status,functional outcomes,and the symptom burden of postoperative patients with pancreatic cancer compared to standard care.AIM To determine how psychological intervention and health education affects the QoL of postoperative patients with pancreatic cancer.METHODS We searched PubMed,EMBASE,Cochrane Library,Web of Science,CINAHL,and MEDLINE from inception to October 2025.Two investigators independently screened studies,extracted data,and assessed bias.Quality was appraised using the Cochrane Risk of Bias tool(RoB 2.0),and the primary effect measure was the standardized mean difference(SMD)derived from a meta-analysis using RevMan 5.4.RESULTS Of the 1613 records initially identified,six studies involving 712 patients were included in the final analysis after applying exclusion criteria.The meta-analysis revealed that,compared with usual care,psychological interventions and health education significantly improved patients’global health status[MD=7.12,95%confidence interval(CI):4.91 to 9.32,P<0.001],physical functioning(SMD=0.61,95%CI:0.37 to 0.85,P<0.001),role functioning(SMD=0.64,95%CI:0.33 to 0.94,P<0.001),emotional functioning(SMD=1.03,95%CI:0.78 to 1.28,P<0.001),dietary digestion(MD=-2.37,95%CI:-3.12 to-1.63,P<0.001),and nursing satisfaction(MD=0.69,95%CI:0.50 to 0.88,P<0.001).CONCLUSION Psychological interventions combined with health education can improve global health status,alleviate symptom burden,and enhance functional outcomes compared to standard care among postoperative patients with pancreatic cancer. 展开更多
关键词 Psychological intervention Health education Pancreatic cancer Quality of life Systematic review Meta-analysis
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Risk factors for anxiety and depression in patients with epilepsy and their relationship with quality of life 认领 引用
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作者 Ning Zong Xu-Ying Liu Fang Chen 《World Journal of Psychiatry》 SCIE 2026年第8期233-243,共11页
BACKGROUND Epilepsy is frequently complicated by anxiety and depression,which severely undermine patients’quality of life(QoL).However,the independent risk factors for these psychiatric comorbidities and their combin... BACKGROUND Epilepsy is frequently complicated by anxiety and depression,which severely undermine patients’quality of life(QoL).However,the independent risk factors for these psychiatric comorbidities and their combined effect on QoL in Chinese patients with epilepsy remain to be comprehensively elucidated.AIM To identify risk factors for epilepsy-related anxiety/depression and their QoL correlation.METHODS A single-center,retrospective study was conducted involving 106 adult patients with epilepsy.Demographic and clinical data were collected.Standardized selfrating scales were used to assess anxiety and depressive symptoms,and QoL was evaluated using the Quality of Life in Epilepsy-31 inventory.Univariate and multivariate logistic regression analyses identified independent risk factors.The performance of the predictive model for comorbidity was evaluated using receiver operating characteristic analysis,calibration,and decision curve analysis.Correlations between psychological symptoms and QoL domains were assessed using Pearson correlation.RESULTS The rates for anxiety,depression,and their co-occurrence were 38.68%,34.91%,and 26.42%,respectively.Multivariate analysis identified unemployment and high seizure frequency(>2/month)as independent risk factors for anxiety.For depression,unemployment,polytherapy(>2 antiepileptic drugs),and high seizure frequency were significant risk factors.Incorporation of unemployment,polytherapy,high seizure frequency,and long duration of disease in the comorbidity model predicted outcome well(area under the receiver operating characteristic curve=0.81)thereby indicating its good clinical utility.Patients who had comorbidity scored significantly lower on the Quality of Life in Epilepsy-31 across all domains.Anxiety and depression severity correlated significantly negatively with all domains of QoL(P<0.05).The strongest correlation was found between depression and total QoL which had(r=-0.65,P<0.001).CONCLUSION Anxiety and depression are highly prevalent in Chinese epilepsy patients,driven by unemployment,uncontrolled seizures,polytherapy,and chronicity,and profoundly impair QoL,underscoring the need for integrated care. 展开更多
关键词 Patients with epilepsy Anxiety Depression Risk factors Quality of life
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