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Acupuncture therapy for angina pectoris:a systematic review 认领 引用 被引量：13
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作者 Ji Chen Yulan Ren +2 位作者 Yong Tang Zhengjie Li Fanrong Liang 《Journal of Traditional Chinese Medicine》 SCIE CSCD 2012年第4期494-501,共8页
OBJECTIVE： To assess the effectiveness and safety of acupuncture therapy for angina pectoris. METHODS： Randomized controlled trials （RCTs） concerned with acupuncture treatment of angina pectoris were identified by... OBJECTIVE： To assess the effectiveness and safety of acupuncture therapy for angina pectoris. METHODS： Randomized controlled trials （RCTs） concerned with acupuncture treatment of angina pectoris were identified by searching Academic Source Premier, MEDLINE, Science Citation Index Expanded, and three Chinese databases （China biol- ogy medicine database, China national knowledge infrastructure, and VlP database for Chinese techni- cal periodicals）. The valid data were extracted in ac- cordance with our inclusion and exclusion criteria. The main outcomes of the included studies were synthesized using Revman 5.1. RESULTS： Twenty-one articles on 16 individual studies were included and evaluated as having high or moderate risk of bias according to the stan- dards of the Cochrane Collaboration. Meta-analysis indicated that acupuncture combined with conven- tional drugs （ACCD） was superior to conventional drugs alone in reducing the incidence of acute myocardial infarction （AMI） [0R=0.18, 95%CI （0.04,0.84）, P=0.03]. Moreover, ACCD was superior to con- ventional drugs in the relief of angina symptoms [0R=4.23, 95%C/（2.73, 6..56）, P〈0.00001], and im- provement of electrocardiography （ECG） [0R=2.61, 95%C/（1.83, 3.73）, P〈0.00001]. Acupuncture by it- self was also superior to conventional drugs for angi- na symptoms [0R=3.59, 95%C/（1.76, 7.92）, P=0.0004] and ECG improvement [0R=3.07, 95%C/（1.54, 6.10）, P=0.001]. ACCD was superior to conventional drugs in shortening the time to onset of angina relief [WMD=-1.40, 95% CI （-1.65, -1.15）, P〈 0.00001]. However, the time to onset was signifi- cantly longer for acupuncture treatment than for conventional treatment alone [WMD=2A3, 95%O （1.63, 3.23）, P〈0.000 01]. CONCLUSION： ACCD reduced the occurrence of AMI, and both acupuncture and ACCD relieved an- gina symptoms and improved ECG. However, com- pared with conventional treatment, acupuncture showed a longer delay before its onset of action. This indicates that acupuncture is not suitable for emergency treatment of heart attack. Owing to the poor quality of the current evidence, the findings of this systematic review need to be verified by more RCTs to enhance statistical power. 展开更多
关键词 Acupuncture therapy Randomizedcontrolled trial Efficacy Review Meta-analysis
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Safety and efficacy of carbon dioxide insufflation during gastric endoscopic submucosal dissection 认领 引用 被引量：9
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作者 Jun Takada Hiroshi Araki +5 位作者 Fumito Onogi Takayuki Nakanishi Masaya Kubota Takashi Ibuka Masahito Shimizu Hisataka Moriwaki 《World Journal of Gastroenterology》 SCIE CAS 2015年第26期8195-8202,共8页
AIM: To compare the safety and efficacy of carbon dioxide(CO2) and air insufflation during gastric endoscopic submucosal dissection(ESD).METHODS: This study involved 116 patients who underwent gastric ESD between Janu... AIM: To compare the safety and efficacy of carbon dioxide(CO2) and air insufflation during gastric endoscopic submucosal dissection(ESD).METHODS: This study involved 116 patients who underwent gastric ESD between January and December 2009.After eliminating 29 patients who fit the exclusion criteria,87 patients,without known pulmonary dysfunction,were randomized into the CO2 insufflation(n = 36) or air insufflation(n = 51) groups.Standard ESD was performed with a CO2 regulation unit(constant rate of 1.4 L/min) used for patients undergoing CO2 insufflation.Patients received diazepam for conscious sedation and pentazocine for analgesia.Transcutaneous CO2 tension(Ptc CO2) was recorded 15 min before,during,and after ESD with insufflation.Ptc CO2,the correlation between Ptc CO2 and procedure time,and ESD-related complications were compared between the two groups.Arterial blood gases were analyzed after ESD in the first 30 patients(12 with CO2 and 18 with air insufflation) to assess the correlation between arterial blood CO2 partial pressure(Pa CO2) and Ptc CO2.RESULTS: There were no differences in respiratoryfunctions,median sedative doses,or median procedure times between the groups.Similarly,there was no significant difference in post-ESD blood gas parameters,including Pa CO2,between the CO2 and air groups(44.6 mm Hg vs 45 mm Hg).Both groups demonstrated median p H values of 7.36,and none of the patients exhibited acidemia.No significant differences were observed between the CO2 and air groups with respect to baseline Ptc CO2(39 mm Hg vs 40 mm Hg),peak Ptc CO2 during ESD(52 mm Hg vs 51 mm Hg),or median Ptc CO2 after ESD(50 mm Hg vs 50 mm Hg).There was a strong correlation between Pa CO2 and Ptc CO2(r = 0.66; P < 0.001).The incidence of Mallory-Weiss tears was significantly lower with CO2 insufflation than with air insufflation(0% vs 15.6%,P = 0.013).CO2 insufflation did not cause any adverse events,such as CO2 narcosis or gas embolisms.CONCLUSION: CO2 insufflation during gastric ESD results in similar blood gas levels as air insufflation,and also reduces the incidence of Mallory-Weiss tears. 展开更多
关键词 Carbon dioxide Gastric endoscopic submucosaldissection Insufflation Mallory-Weiss tear Randomizedcontrolled trial
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Observation on clinical efficacy of acupuncture combined with direct moxibustion with fine-strip moxa for 62 cases of herpes zoster 认领 引用 被引量：3
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作者 李梦 苟春雁 王毅刚 《World Journal of Acupuncture-Moxibustion》 CAS 2014年第2期15-18,24,共4页
Objective To evaluate the clinical effect of acupuncture combined with direct moxibustion with fine-strip moxa for herpes zoster. Methods Sixty-two patients with herpes zoster were randomly divided into two groups acc... Objective To evaluate the clinical effect of acupuncture combined with direct moxibustion with fine-strip moxa for herpes zoster. Methods Sixty-two patients with herpes zoster were randomly divided into two groups according to attendance number, 32 in acupuncture group and 30 in western medicine group. The patients in the acupuncture group were treated by acupuncture at the nidus-related nerve segments Jiaji （夹脊 EX-B2） in combination with direct moxibustion with fine-strip moxa, while the patients in the western medicine group were treated by oral valaciclovir hydrochloride, vitamin B1, vitamin B12. The times of response, incrustation and decrustation were observed respectively, and pain relief degree of the two groups were compared. Results The response time, incrustation time and decrustation time of the acupuncture group were all less than those of the western medicine group [（1.74±0.43） days vs （3.86±0.58） days, （2.03±0.52） days vs （5.46±0.65） days, （5.14±0.33） days vs （8.34±0.59） days, all P〈O.05]. The pain relief degree （VAS score）, and pain duration in the acupuncture group were all higher obviously than those of the western medicine group [（10.41±12.1） vs （15.63±11.39）, （4.78±0.45） days vs （8.12±0.63） days, all P〈O.05]. The total effective rate of the acupuncture group was 96.9% （31/32）and that of the western medicine group was 90% （27/30）, thus the therapeutic effect of acupuncture group was better than that of western medicine group （P〈0.05）. Conclusion The therapeutic effect of acupuncture combined with direct moxibustion with fine-strip moxa is remarkable. It can effectively control the development of herpes zoster, alleviate pain and shorten therapy periods. It is worthy to be promoted and applied. 展开更多
关键词 herpes zoster acupuncture therapy fine-strip moxa randomizedcontrolled trial
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The Clinical Randomized Controlled Trial on the Safety and Efficacy of Polyethersulfone Membrane Dialyzer in the Maintenance of Hemodialysis Patients 认领 引用
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作者 GU Ying-li LIN Fu-jun ZHU Chun JIANG Geng-ru 《Chinese Journal of Biomedical Engineering(English Edition)》 CAS 2010年第4期148-155,共8页
Objective： To observe the safety and efficacy of polyethersulfone membrane dialyzer used by chronic renal failure patients in clinical maintenance hemodialysis （MHD）. Methods： From January to February 2009, 36 pat... Objective： To observe the safety and efficacy of polyethersulfone membrane dialyzer used by chronic renal failure patients in clinical maintenance hemodialysis （MHD）. Methods： From January to February 2009, 36 patients were recruited from Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine. The experiment was approved by the ethnical committee of Xinhua Hospital and under permissions fronl patients. All the patients were randomized into polyethersulfone group （PES, n=18） and polysulfone group （PS, n=18）. Hemodialysis was given by using Fresenius 4008S capacity-controlled dialyser and ultra-purified bicarbonate dialysate, more than 3.5 h each time, three times per-week, followed by heparin anticoagulation for a week, three times totally. Changes in blood urea nitrogen （BUN）, serum creatinine （Set）, phosphate （p2＋）, hemoglobin and albumin levels were determined for the efficacy and safety evahlation. Results： The serum BUN, Set and p2＋ concentrations significantly reduced after hemodialysis with different dialyzers, and the decrease amplitude of two groups was equivalent（P〉0.05）. The clearance rate of the serum BUN and Scr had no significant difference among two groups（P〉O.05）. The clearance rate （ml/min） of the sermn P^2＋ was 144.57 ±27.83 v.s. 117.15 ±22.77 in two groups. The clearance rate of the serum p^2＋ in PES group was more than that in PS group, and the difference was significant between two groups （P=0.0001）. It was indicated that PES and PS membrane could efficiently eliminate serum mieromolecule solute in MHD patients, so PES membrane excelled PS membrane in eliminating serum p2＋. The hemodialysis safety index, for example serum hemoglobin, albumin and blood pressure, had no significant difference between the two groups before and after hemodialysis （P〉0.05）. Conclusion： The efficacy and safety of the PES hollow fiber membrane dialyzer is equivalent to that of the imported PS membrane dialyzer in hemodialysis for MHD patients. The PES membrane excels PS membrane in eliminating sermn p^2＋. 展开更多
关键词 hemodialysis polyethersulfone membrane dialyzer randomizedcontrolled trial solute blood phosphate
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A meta-analysis of Duhuo Jisheng decoction combined with non-operative therapy on lumbar disc herniation 认领 引用
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作者 Chen-Yang Zhang Ling Li +2 位作者 Zhao-Yong Li Xiao-Nan Wu Shao-Feng Yang 《TMR Clinical Research》 2019年第3期115-124,共10页
Objective:To systematically evaluate the cllinical efficacy of Duhuo Jisheng decoction(DHJSD)combined with non-surgical therapy on lumbar disc herniation(LDH).Methods:China Science and Technology Journal Database(VIP)... Objective:To systematically evaluate the cllinical efficacy of Duhuo Jisheng decoction(DHJSD)combined with non-surgical therapy on lumbar disc herniation(LDH).Methods:China Science and Technology Journal Database(VIP),Chinese National Knowledge Infrastructure(CNKI),WanFang Data,PubMed were searched and eligible randomized controlled clinical trials(RCTs)were included.Two reviewers evaluated the quality of the included RCTs and extracted data independently.Then,data analysis was performed with RevMetn 4.2 software.Results:A total of 18 RCTs were enrolled,including 1682 patients.Meta-analysis results showed that the overall response rate of DHJSD combined with non-operative therapy group(treatment group)in the treatment of LDH was better than that of the non-operative therapy group(control group)[OR=4.29,95%CI(3.19,5.76),P<0.001].JOA score of the treatment group was significantly higher than that of control group[OR=3.96,95%CI(3.4,4.52),P<0.001].VAS score was dramatically lower in the treatment group than the control group[OR=-1.58,95%CI(-1.97,-1.18),P<0.001].Conclusion:The clinical efficacy of DHJSD combined with non-surgical therapy is better than that of non-surgical therapy alone.However,due to the low quality of the included literatures,large-scale and high-quality RCTs are still needed for further confirmation. 展开更多
关键词 Duhuo Jisheng decoction(DHJSD) Lumbar disc herniation(LDH) Meta-Analysis Randomizedcontrolled trials(RCTs)
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Electroacupuncture in Treating Depression:A Randomized Controlled Study 认领 引用 被引量：5
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作者 Chen Xiu-ling Xu Kai +2 位作者 Luo Ren-han Lin Miao-jun Hong Jue 《Journal of Acupuncture and Tuina Science》 CAS 2013年第1期42-45,共4页
Objective: To observe the clinical efficacy of electroacupuncture in treating depression. Methods: By a randomized controlled study method, sixty patients with depression were randomized into an electroacupuncture gro... Objective: To observe the clinical efficacy of electroacupuncture in treating depression. Methods: By a randomized controlled study method, sixty patients with depression were randomized into an electroacupuncture group and a medication group, 30 in each. The electroacupuncture group was treated with electroacupuncture, and the medication group was orally administrated Paroxetine tablets. They were evaluated by using Hamilton Depression Scale (HAMD) before and after treatments and the safety was also assessed. Results: The total effective rate was 83.3% in the electroacupuncture group versus 60.0% in the medication group, and the difference was statistically significant (P<0.05). The electroacupuncture group was superior to the medication group in comparing the improvement of HAMD scores after treatment (P<0.05). Conclusion: Electroacupuncture is an effective approach in treating depression. 展开更多
关键词 Acupuncture Therapy Electroacupuncture Depression RandomizedControlled Trial
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No Additional Cholesterol-Lowering Effect Observed in the Combined Treatment of Red Yeast Rice and Lactobacillus Casei in Hyperlipidemic Patients:A Double-Blind Randomized Controlled Clinical Trial 认领 引用 被引量：1
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作者 Chien-Ying Lee Min-Chien Yu +8 位作者 Wu-Tsun Perng Chun-Che Lin Ming-Yung Lee Ya-Lan Chang Ya-Yun Lai Yi-Ching Lee Yu-Hsiang Kuan James Cheng-Chung Wei Hung-Che Shih 《Chinese Journal of Integrative Medicine》 SCIE CAS CSCD 2017年第8期581-588,共8页
Objective：To observe the effect of combining red yeast rice and Lactobacillus casei（L.casei）in lowering cholesterol in patients with primary hyperlipidemia,the later has also been shown to remove cholesterol in in ... Objective：To observe the effect of combining red yeast rice and Lactobacillus casei（L.casei）in lowering cholesterol in patients with primary hyperlipidemia,the later has also been shown to remove cholesterol in in vitro studies.Methods：A double-blind clinical trial was conducted to evaluate the cholesterol-lowering effect of the combination of red yeast rice and L.casei.Sixty patients with primary hyperlipidemia were recruited and randomized equal y to either the treatment group（red yeast rice＋L.casei）or the control group（red yeast rice＋placebo）.One red yeast rice capsule and two L.casei capsules were taken twice a day.The treatment lasted for 8 weeks,with an extended follow-up period of 4 weeks.The primary endpoint was a difference of serum low-density lipoprotein cholesterol（LDL-C）level at week 8.Results：At week 8,the LDL-C serum level in both groups was lower than that at baseline,with a decrease of 33.85±26.66 mg/dL in the treatment group and 38.11±30.90 mg/dL in the control group;however,there was no statistical difference between the two groups（P〉0.05）.The total cholesterol was also lower than the baseline in both groups,yet without a statistical difference between the two groups.The only statistical y significant difference between the two groups was the average diastolic pressure at week 12,which dropped by 2.67 mm Hg in the treatment group and increased by 4.43 mm Hg in the placebo group（P〈0.05）.The antihypertensive activity may be associated with L.casei.Red yeast rice can significantly reduce LDL-C,total cholesterol and triglyceride.Conclusion：The combination of red yeast rice and L.casei did not have an additional effect on lipid profiles. 展开更多
关键词 red yeast rice Lactobacillus casei,low-density lipoprotein cholesterol randomizedcontrolled trial
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