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Multi-Dimensional Collaborative Optimization Strategy for Control Parameters of Thermal-Energy Storage Integrated Systems Considering Frequency Regulation Losses 认领 引用
1
作者 Zezhong Liu Jinyu Guo +1 位作者 Xingxu Zhu Junhui Li 《Energy Engineering》 EI 2026年第3期361-390,共30页
With the increasing penetration of renewable energy,the coordination of energy storage with thermal power for frequency regulation has become an effective means to enhance grid frequency security.Addressing the challe... With the increasing penetration of renewable energy,the coordination of energy storage with thermal power for frequency regulation has become an effective means to enhance grid frequency security.Addressing the challenge of improving the frequency regulation performance of a thermal-storage primary frequency regulation system while reducing its associated losses,this paper proposes a multi-dimensional cooperative optimization strategy for the control parameters of a combined thermal-storage system,considering regulation losses.First,the frequency regulation losses of various components within the thermal power unit are quantified,and a calculation method for energy storage regulation loss is proposed,based on Depth of Discharge(DOD)and C-rate.Second,a thermal-storage cooperative control method based on series compensation is developed to improve the system’s frequency regulation performance.Third,targeting system regulation loss cost and regulation output,and considering constraints on output overshoot and system parameters,an improved Particle Swarm Optimization(PSO)algorithm is employed to tune the parameters of the low-pass filter and the series compensator,thereby reducing regulation losses while enhancing performance.Finally,simulation results demonstrate that the total loss cost of the proposed control strategy is comparable to that of a system with only thermal power participation.However,the thermal power loss cost is reduced by 42.16%compared to the thermal-only case,while simultaneously improving system frequency stability.Thus,the proposed strategy effectively balances system frequency stability and economic efficiency. 展开更多
关键词 Frequency regulation losses of thermal power units energy storage frequency regulation losses series compensation enhanced particle swarm optimization algorithm primary frequency regulation
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An Optimization-Based Consensus Approach for Distributed Density Regulation of Swarms 认领 引用
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作者 Di Cui Huiping Li 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2026年第5期1248-1250,共3页
Dear Editor,This letter addresses the distributed density regulation problem for large-scale robotic swarms.To accommodate swarm size,system dynamics are formulated within an Eulerian framework,modeling the swarm’s a... Dear Editor,This letter addresses the distributed density regulation problem for large-scale robotic swarms.To accommodate swarm size,system dynamics are formulated within an Eulerian framework,modeling the swarm’s actual density distribution(ADD)as a probability distribution,with state transition probabilities governed by a Markov matrix. 展开更多
关键词 markov matrix state transition probabilities eulerian frameworkmodeling distributed density regulation density distribution add probability distributionwith distributed density regulation problem robotic swarmsto
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Classification of Influencing Factors and Mechanisms Underlying Emotion Regulation Choice 认领 引用
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作者 Shi-Min Chen Li-Li Wang 《International Journal of Mental Health Promotion》 2026年第6期70-95,共26页
Backgrounds:The factors influencing emotion regulation choice(ERC)are numerous,raising the question of how to classify them systematically.Methods:This study proposed a framework of four first-order factors—the emoti... Backgrounds:The factors influencing emotion regulation choice(ERC)are numerous,raising the question of how to classify them systematically.Methods:This study proposed a framework of four first-order factors—the emotion to be regulated,emotion regulation goals,emotion regulation resources,and psychosocial context—by integrating several key theories of ERC,including the Action Control Theory of Emotion Regulation,the Extended Process Model of Emotion Regulation,the Process-specific Timing Framework Theory,the Selection,Optimization,and Compensation model of Emotion Regulation,and the Emotion as Social Information Theory.Results:This research also provided a detailed examination of the effects of multiple second-order and third-order factors—those either unaddressed or insufficiently covered in previous reviews—on ERC.These factors included the nature of the emotion,emotional intensity,hedonic versus instrumental goals,cognitive factors(such as cognitive resources,executive functions,and cognitive abilities),personality(encompassing the Big Five Personality,attachment,and self-esteem),social support,and interpersonal contexts.Conclusion:Additionally,how gender and age exert an influence on ERC through differences in goals and cognition was examined.Future studies can further explore the interactive effect of different factors on ERC,and the neural correlates of ERC. 展开更多
关键词 Emotion regulation choice emotional intensity emotional regulation goal emotional regulation resource psychosocial context
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Epigenetic mechanisms of heterosis in tea plants:insights into m6A RNA methylation and miRNA-mediated regulation 认领 引用 被引量：2
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作者 Xiansheng Liao Mengting Tang +4 位作者 Wenlong Lei Hongzheng Lin Shan Jin Pengjie Wang Naixing Ye 《Horticultural Plant Journal》 SCIE CAS CSCD 2026年第6期1479-1491,共13页
Heterosis is fundamental to modern tea breeding practices and is widely used in tea production.However,the epigenetic regulatory mechanisms underlying heterosis in tea plants remain relatively unknown.In this study,we... Heterosis is fundamental to modern tea breeding practices and is widely used in tea production.However,the epigenetic regulatory mechanisms underlying heterosis in tea plants remain relatively unknown.In this study,we integrated transcriptome,RNA methylation,and miRNA profile information to understand the epigenetic basis of heterosis in tea plants.We found that although m6A methylation modifications and miRNAs are highly conserved in tea plants,a significant number of differentially methylated and differentially expressed genes and differentially expressed miRNAs showed non-additive genetic effects in the hybrid.This non-additive expression is closely related to the synthesis of secondary metabolites and plant stress responses,implying that the regulation of these genes plays a key role in enhancing the quality and stress tolerance of hybrids.Through comprehensive analyses of the transcriptome,m6A methylation modifications,and miRNAs,we established a multi-level regulatory network,revealing the molecular mechanisms by which m6A methylation modifications and miRNAs drive heterosis in tea plants from the transcriptional to the post-transcriptional regulatory level.This multi-level regulatory network not only deepens our understanding of tea plant heterosis but also provides novel insights for further studies on the role of m6A methylation and miRNAs in tea plant heterosis. 展开更多
关键词 Camellia sinensis Heterosis Epigenetic Post-transcriptional regulation Multi-level regulatory network
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Neural Network-Based Switching Output Regulation Control for High-Speed Nano-Positioning Stages 认领 引用 被引量：1
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作者 Hongwei Sun Ning Xing +4 位作者 Jiayu Zou Yuqi Rong Yang Shi Han Ding Hai-Tao Zhang 《Engineering》 SCIE EI CSCD 2026年第2期227-235,共9页
This study establishes a high-speed nano-positioning stage composed of a symmetrically driven structure with multiple parallel-bonded thin piezoelectric ceramic layers capable of performing micro-or nanoscale manipula... This study establishes a high-speed nano-positioning stage composed of a symmetrically driven structure with multiple parallel-bonded thin piezoelectric ceramic layers capable of performing micro-or nanoscale manipulations.Accordingly,a neural-network-based switching output regulation controller(NNSORC)was developed to compensate for the associated hysteresis nonlinearity.To address the challenges of slow floating-point computation speeds and low compilation efficiency,a closed-loop control system with a field-programmable gate array–central processing unit(FPGA–CPU)dual-layer data-processing framework was developed.A feedback linearization method was designed to linearize the hysteresis nonlinearity of the framework,resulting in a switching-tracking error system.With the assistance of Lyapunov theory and an average dwell time technique,sufficient conditions were derived to ensure the asymptotic stability of the NN-SORC governing closed-loop system using the switching reference signals often encountered in realistic micro-ano-scale detection and manufacturing processes.Finally,extensive comparative experiments were conducted to verify the effectiveness and superiority of the proposed NN-SORC scheme. 展开更多
关键词 High-speed nano-positioning stage Switched system Intelligent control Output regulation control
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Pyrrolic-Nitrogen-Enriched Aerogels With Magnetic Responsiveness Enable Cooperative Hydrogen-Bond Regulation for High-Performance Solar Interfacial Evaporation 认领 引用
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作者 Dongxue Wang Rui Yan +6 位作者 Mengshu Xu Chunyu Yang Jingbo He Shuohao Shi Zhuoran Yang Jian Huang Wei Guo 《Carbon Energy》 SCIE EI CAS CSCD 2026年第4期205-218,共14页
Although solar-driven interfacial evaporation offers a sustainable pathway for desalination and wastewater remediation,its practical implementation remains limited by both the high vaporization enthalpy and rigid hydr... Although solar-driven interfacial evaporation offers a sustainable pathway for desalination and wastewater remediation,its practical implementation remains limited by both the high vaporization enthalpy and rigid hydrogen-bond network of water and performance degradation in complex water matrices.This study introduces a dual-regulation strategy that integrates internal structural optimization with external-field physical modulation.In particular,an Fe-catalyzed pyrrole polymerization process yields a carbon-based aerogel(CPP)with integrated ferromagnetism and enriched pyrrolic nitrogen sites.This synergy increases the intermediate-water fraction,reduces vaporization enthalpy,and accelerates phase-transition kinetics.Under onesun illumination(1 kW m-2),the CPP evaporator achieves an evaporation rate and efficiency of 2.78 kg m-2h-1 and 84.0%,respectively,without magnetic assistance.After applying a 10 m T magnetic field,these values increase to 3.30 kg m-2h-1 and 99.7%,respectively.Moreover,the system demonstrates stable salt self-cleaning in seawater,resilience in organic wastewater,and multifunctionality in pollutant removal,achieving a tetracycline degradation rate of 89% when coupled with a solar-driven advanced oxidation process.This study offers a generalizable framework that couples structural design with external-field modulation for next-generation solar evaporation systems. 展开更多
关键词 aerogel dual-regulation strategy hydrogen-bond regulation multifunctional water treatment solar interfacial evaporation
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Emotion-cognition dysregulation in major depression:Multidimensional biases,neural circuit imbalance,and translational opportunities 认领 引用
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作者 Yi Gu Yi-Xu Wang +1 位作者 Wen-Juan Xia Jun Wang 《World Journal of Psychiatry》 SCIE 2026年第3期78-88,共11页
Major depressive disorder is increasingly conceptualized as a disorder of emotion-cognition dysregulation.Convergent evidence shows reliable negative biases in recognition and attention(facilitated capture by threat,i... Major depressive disorder is increasingly conceptualized as a disorder of emotion-cognition dysregulation.Convergent evidence shows reliable negative biases in recognition and attention(facilitated capture by threat,impaired disengagement),overgeneral and negatively weighted autobiographical memory,blunted processing of positiveewarding stimuli,and preferential reliance on maladaptive regulation strategies(rumination,suppression).At the systems level,taskbased and resting-state functional magnetic resonance imaging support the presence of a limbic-prefrontal imbalance-amygdala/insula hyperreactivity with reduced top-down control from dorsolateral/ventromedial prefrontal cortex and anterior cingulate-accompanied by large-scale network disruption(default-mode hyperconnectivity and weakened coupling to salience and frontoparietal control networks).Electrophysiology adds temporal specificity:Enhanced early components to negative faces(e.g.,N170),reduced late positive potential to appetitive cues,diminished prefrontal theta power,altered gamma activity,and perturbed theta-gamma coupling.Mechanistic contributors include monoaminergic imbalance,hypothalamic-pituitary-adrenal-axis activation,inflammatory signaling,and excitatory-inhibitory disequilibrium,moderated by cognitive style,early adversity,sex,and age.Translational opportunities span composite behavioralneural signatures for diagnosis and stratification,risk forecasting,and treatment selection/monitoring;partial normalization of biases and circuits has been observed with cognitive behavioral therapy,selective serotonin reuptake inhibitor/serotonin-norepinephrine reuptake inhibitor,and noninvasive neuromodulation(repetitive transcranial magnetic stimulationranscranial direct current stimulation),especially with imaging-guided targeting.Priorities include stan-dardized paradigms,longitudinal multimodal designs,and mechanistic modeling to qualify biomarkers and enable mechanism-guided,precision interventions. 展开更多
关键词 Major depressive disorder Emotion-cognition dysregulation Amygdala-prefrontal circuitry Attentional bias Emotion regulation Biomarkers
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Alkalinity regulation of bauxite residue mediated by Penicillium oxalicum:Insights into carbon components dynamics 认领 引用
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作者 Shengguo Xue Ziying Zhang +5 位作者 Xinfeng Qin Yifan Jiang Zhiqiang Zhao Mingli Wang Jinglan Ma Feng Zhu 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第6期442-451,共10页
Microbially-driven alkaline neutralization during soil formation in bauxite residue is a promising technology toward sustainable management of alkaline solid-waste landscapes worldwide.However,our knowledge regarding ... Microbially-driven alkaline neutralization during soil formation in bauxite residue is a promising technology toward sustainable management of alkaline solid-waste landscapes worldwide.However,our knowledge regarding the impacts of microorganisms on the organic components dynamics involved in alkalinity regulation remains rather limited.In this study,we performed water-phase and solid-phase microcosm experiments using Penicillium oxalicum and sugarcane bagasse with gradient addition amount.Multi-spectroscopic techniques and metabolomic analysis were employed to investigate the combined effects of alkaline stabilization and carbon components dynamics in bauxite residue.An addition of 5‰of sugarcane bagasse was appropriate to reduce the pH of bauxite residue from 10.16 to30%.Spectroscopic analysis verified that sugarcane bagasse predominantly formed connections with humic substances,establishing zones rich in carbon containing fulvic and humic acids,which promoted the bio-production of lowmolecular-weight-organic acids.Metabolomic analysis identified 631 compounds,with 126 associated to carbon metabolism.Notably,tricarboxylic acid cycle(TCA)pathway involving acetate and oxalate were significantly upregulated following the combined application.Mantel-test analysis further showed positive correlations between 5-hydroxyindoleacetic acid and 5-phosphonooxy-L-lysine and alkalinity regulation,proving that the combined application regulated alkalinity by improving amino acid metabolism and carbon skeleton reutilization.Overall,our findings highlighted the metabolic mechanisms involved in alkalinity regulation during soil formation process mediated by P.oxalicum and provided an optimized solution for microbially-driven alkaline regulation within bauxite residue. 展开更多
关键词 Bauxite residue Penicillium oxalicum Carbon component Metabolomics Alkaline regulation Soilization
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Copper ion-antibiotic complexation inhibits photochemical transformation of fluoroquinolones via electron redistribution and reactivity regulation 认领 引用
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作者 Bo Gong Chang Xu +4 位作者 Shan Zhao Xiao-Min Sun Shu-Guang Wang Xian-Zheng Yuan Chao Song 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第4期584-592,共9页
The photochemical transformation of fluoroquinolones(FQs) represents a crucial environmental phenomenon eliciting growing concern. Nevertheless, the impact and mechanisms of ubiquitously coexisting copper ions, i.e.,... The photochemical transformation of fluoroquinolones(FQs) represents a crucial environmental phenomenon eliciting growing concern. Nevertheless, the impact and mechanisms of ubiquitously coexisting copper ions, i.e.,Cu(Ⅱ), remain elusive. Here, the role of Cu(Ⅱ) in the photochemical transformation of FQs was systematically investigated via experimental characterizations and theoretical simulations. Cu(Ⅱ) markedly inhibited the photolysis of levofloxacin(LEV), a representative FQs model, from 0.0078 to 0.0040 min-1 after a 100-min irradiation under simulated sunlight with the molar ratio of Cu(Ⅱ): LEV at 1:1. The micro-level mechanisms were explored, including the ligand-to-metal charge transfer in complexation, modifications to reactive sites and activities with various reactive species, and higher hole-electron separation extents. In addition, the triplet excited state, singlet oxygen, and hydroxyl radical in LEV and LEV-Cu(Ⅱ) with 1:1 molar ratio played pivotal roles in the transformation, contributing 20.77 %/20.02 %, 13.87 %/14.59 %, and 7.96 %/4.68 %, respectively. Furthermore, considering more FQs models, the inhibition of Cu(Ⅱ) on the transformation was found to universally exist in ciprofloxacin, enoxacin, enrofloxacin, norfloxacin, ofloxacin and pefloxacin, and their multiple molecular descriptors were changed with a same tendency. This work provides a comprehensive understanding of the transformation of antibiotics within complex aqueous matrices, contributing to further estimation of antibiotics removal and ecological risks. 展开更多
关键词 Fluoroquinolones Photochemical transformation Copper complexation Reactivity regulation Molecular mechanism
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Real-time regulation of zinc deposition/stripping by self-assembled molecule brush targeting proton for highly reversible Zn-ion battery 认领 引用
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作者 Zeping Liu Lijie Wang +5 位作者 Zeren Zhou Qixian Zhang Yixiang Zhang Wei Han Qiaoyan Lin Lishuang Fan 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第2期541-549,I0012,共9页
Currently,zinc anodes are facing problems such as the growth of zinc dendrites and the frequent occurrence of side reactions,while existing additive strategies are still challenging due to the poor stability of the ad... Currently,zinc anodes are facing problems such as the growth of zinc dendrites and the frequent occurrence of side reactions,while existing additive strategies are still challenging due to the poor stability of the adsorption layer and the ambiguous mechanisms of action.In this study,a highly stable Vani molecular brush additive was designed.The additive effectively inhibits H2 generation by targeting and anchoring H+in the inner Helmholtz layer,and reduces the water activity by constructing an enhanced hydrogen bonding network through the interaction with water molecules,thus inhibiting the parasitic side reactions on the zinc anode.In addition,the dynamic interfacial molecular layer can regulate and buffer the interfacial Zn2+for highly reversible plating/stripping.Experiments show that the symmetric cell cycle life is as long as 3760 h at a Vani content of only 2×10-3 g L-1 with a current density of5 mA cm-2.The cycle life of the Zn‖MnO2 and Zn‖Zn0.58V2O5 H2O full battery is significantly improved.This study deepens the understanding of the working mechanism of the zinc electrode interface and provides new ideas for non-sacrififcial trace additive design. 展开更多
关键词 Zinc ion battery Zinc Anode Dynamic regulation Molecule brush Proton
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A transformable DNA Nano-windmill for the activation and regulation of the heterodimerization receptors across RTK families 认领 引用
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作者 Kun Liu Junjun Lu +7 位作者 Jincheng Lin Yulin Cong Xiongfeng Luo Zihong Huang Tianyi Zhang Miao Wang Zhiyong Xie Hao Li 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第4期556-559,共4页
Heterodimerization of receptor tyrosine kinases(RTKs)plays unique roles in cell signaling and functions.However,engineering heterodimerization of multiple receptors remains largely unexplored.Herein,we developed an ap... Heterodimerization of receptor tyrosine kinases(RTKs)plays unique roles in cell signaling and functions.However,engineering heterodimerization of multiple receptors remains largely unexplored.Herein,we developed an aptamer-based DNA Nano-windmill(TA3)to regulate heterodimerization of three different RTK families,simultaneously activating fibroblast growth factor receptor 1(FGFR1),hepatocyte growth factor receptor(Met)and epidermal growth factor receptor(EGFR)signaling.It is the first DNA Nanowindmill that activates heterodimerization of FGFR1,Met and EGFR,leading to the down-stream signals transduction,such as the phosphorylation of protein kinase B(Akt)and extracellular regulated protein kinases(Erk),inducing the cell migration and proliferation.We further designed transformable DNA Nanowindmill(TMA)that can convert DNA Nano-windmill into DNA Nano-kite using complementary strands or small molecules to reduce the activation of specific receptor.We believe that the DNA Nano-windmill for heterodimerization of different RTK families have potential applications in biomedicine fields. 展开更多
关键词 DNA Nano-windmill Heterodimerization Receptor tyrosine kinases Aptamer Cell regulation
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Biomass-derived amphiphilic nitrogen-doped carbon dots:Molecular design,interfacial regulation,and enhanced oil recovery performance 认领 引用
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作者 Yu Wu Yan-Cheng Zheng +2 位作者 Jian Mu Fu-Chang You Zheng-Yu Li 《Petroleum Science》 SCIE EI CAS CSCD 2026年第4期2046-2065,共20页
In response to the overlooked influence of precursor molecular structure on interfacial performance in the application of amphiphilic carbon dots(CDs)for enhanced oil recovery(EOR),this study synthesized nitrogen-dope... In response to the overlooked influence of precursor molecular structure on interfacial performance in the application of amphiphilic carbon dots(CDs)for enhanced oil recovery(EOR),this study synthesized nitrogen-doped CDs(NCDs,FG,and TA series)using biomass-derived precursors via carbonization,amidation,quaternization,and alkylation.The relationships between precursor structure,surface functionality,interfacial behavior,and oil displacement performance were systematically investigated.TA-derived NCDs exhibited higher surface polarity and amphiphilicity due to abundant carboxyl groups,while increasing alkyl chain length enhanced hydrophobicity and suppressed surface defects.TA-NCDsL16 showed the best interfacial properties,with a critical micelle concentration(CMC)of 0.104 g/L,γCMC of 24.71 mN/m,and zeta potential of+67.80 mV.Under NaCl concentrations ranging from 0 to 12 wt%,the oil–water interfacial tension decreased to a minimum of 0.00151 mN/m,and the contact angle dropped to 16.3°,indicating excellent salt tolerance and wettability reversal capability.In lowpermeability core flooding tests,TA-NCDs-L16 achieved a significantly enhanced final oil recovery of 60.42%,with a 27.26%increase in recovery and a 38.71%reduction in injection pressure.The improved EOR performance was attributed to ultra-low interfacial tension,the formation of high-density polar adsorption layers,and nanoscale size effects that enabled efficient pore-throat penetration and fluid redistribution,thereby facilitating the detachment and mobilization of residual oil.In high-salinity formation water containing Ca2+/Mg2+and under elevated temperatures(50–90℃),further evaluation confirmed that the amphiphilic NCDs maintained strong interfacial activity and sustained wettability reversal.TA-NCDs-L16 retained an ultra-low interfacial tension(~0.002 mN/m)and stable wettability regulation even after 240 h of thermal aging at 80℃,while core flooding still exhibited significant reductions in injection pressure and enhancements in oil recovery.This study clarifies the correlation among precursor structure,functional group configuration,interfacial behavior,and oil displacement efficiency,providing theoretical guidance and material design concepts for the development of carbon-based amphiphilic nanofluids in low-permeability reservoir applications. 展开更多
关键词 Nanofluid flooding Amphiphilic carbon dots Surface functionalization Interfacial regulation Enhanced oil recovery Low-permeability reservoirs
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Transcriptional,epigenetic,and post-translational regulation of plant autophagy 认领 引用
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作者 Yao Wang Chao-Ying Liu +3 位作者 Liang Chen Si-Hai Guo Shi Xiao Hua Qi 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2026年第7期1180-1193,共14页
Autophagy is a highly conserved intracellular recycling process in eukaryotes that delivers cellular components to the lysosome or vacuole for degradation,thereby maintaining intracellular homeostasis.Acting as a qual... Autophagy is a highly conserved intracellular recycling process in eukaryotes that delivers cellular components to the lysosome or vacuole for degradation,thereby maintaining intracellular homeostasis.Acting as a quality control system,autophagy plays a pivotal role in plant growth,development,and adaptation to environmental challenges.The regulation of autophagy under stress conditions involves multi-layered mechanisms,including transcriptional,epigenetic,and post-translational controls.Transcription factors from families such as WRKY,NO APICAL MERISTEM/ARABIDOPSIS TRANSCRIPTION ACTIVATION FACTOR/CUP-SHAPED COTYLEDON(NAC),and basic leucine zipper(bZIP)directly bind to the promoters of autophagy-related(ATG)genes,thereby integrating stress-responsive signal pathways to orchestrate autophagic activity dynamically.Epigenetic modifications,including histone modifications,DNA methylation,N6-methyladenosine(m6A)methylation,and microRNA-mediated silencing,further fine-tune expression of ATG genes in response to changing environments.At the post-translational level,modifications such as phosphorylation,ubiquitination,acetylation,persulfidation,and S-nitrosylation serve as rapid regulatory switches that modulate autophagosome formation under stress.This review summarizes recent advances in elucidating these regulatory layers,highlighting how these regulators collectively modulate autophagy to improve plant tolerance to environmental cues.Unraveling these mechanisms will expand our understanding of the autophagy regulatory network in plants and provide potential strategies for improving stress tolerance in crops. 展开更多
关键词 Autophagy Environmental challenges Transcription factors Epigenetic regulation Post-translational modifications Regulatory network
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Solvation-interphase synergistic regulation empowering high-temperature and fast-charging lithium metal batteries 认领 引用
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作者 Liu Yang Haohan Chen +7 位作者 Yajie Hu Jinyu Tian Yupeng Feng Yuanjian Li Meng Yao Fei Li Jianping Long Anjun Hu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第1期444-452,I0010,共9页
Lithium metal batteries(LMBs)have emerged as pivotal energy storage solutions for electric vehicles and portable electronics.However,their operation under extreme conditions(high-temperature and fast-charging conditio... Lithium metal batteries(LMBs)have emerged as pivotal energy storage solutions for electric vehicles and portable electronics.However,their operation under extreme conditions(high-temperature and fast-charging conditions)faces significant challenges,including accelerated electrolyte decomposition,interfacial instability,and potential thermal runaway risks.To address these challenges,we present a solvation-interphase synergistic regulation strategy using 2-fluorobenzenesulfonamide(2-FBS)as a multifunctional electrolyte additive.The 2-FBS molecule effectively modulates the Li+solvation structure by reducing the coordination of ethylene carbonate(EC)solvent.This transformation suppresses EC-induced parasitic reactions while scavenging superoxide radicals,thereby mitigating gas evolution at electrode interfaces.Upon preferential decomposition,2-FBS further promotes the formation of a robust LiF-Li3N-Li2S-rich interphase with exceptional mechanical strength(Young’s modulus:39.4 GPa).This inorganic-rich hybrid interphase simultaneously enables dendrite-free lithium plating and enhances cathode thermal stability.Consequently,2-FBS-modified electrolyte empowers LiCoO2//Li cells to deliver 82.8%capacity retention after 800 cycles at 55°C and sustain 81.2%capacity retention after 1500 cycles at 4 C.Moreover,practical validation through nail penetration tests confirms the effectiveness of the electrolyte in preventing thermal propagation in fully charged pouch cells.This work establishes a paradigm for enabling reliable battery operation under extreme conditions through synergistic solvation and interphase engineering. 展开更多
关键词 Lithium-metal batteries Electrolyte additives Solvation structure Interphase regulation Pouch cells
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Dual regulation of antiviral IFN response by Scutellariae Radix:Therapeutic implications for influenza 认领 引用
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作者 Li Li Manjing Jiang +9 位作者 Hong Wei Linpan Liang Yunlong Song Dongni Xia Qiang Luo Huimin Huang Xu Li Haisheng Yang Lijun Ning Ying Wu 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2026年第3期756-774,共19页
Scutellariae Radix(SR)is widely used in Chinese medicine for influenza treatment;however,the mechanisms underlying its effect remain unknown.Here,we report,for the first time,that the therapeutic effects of SR on infl... Scutellariae Radix(SR)is widely used in Chinese medicine for influenza treatment;however,the mechanisms underlying its effect remain unknown.Here,we report,for the first time,that the therapeutic effects of SR on influenza involve regulation of antiviral interferons(IFNs),typeⅠand typeⅢIFNs(IFN-Is and IFN-Ⅲs,respectively),particularly through the modulation of IFN-I production and its downstream effects in a cell type-specific manner.SR treatment resulted in symptomatic improvement in A/Puerto Rico/8/34(H1N1)virus(PR8)-infected mice.It exhibited direct antiviral activity in the early stages of virus infection in A/WSN/33(H1N1)(WSN)-infected Madin-Darby canine kidney(MDCK)cells.Next,we investigated the effects of SR on the upstream antiviral IFN pathways and downstream effects in human lung adenocarcinoma(A549)cells,human monocytic leukemia(THP-1)cells,and neutrophils(Neu).SR exhibited dual regulatory roles,enhancing the production and activity of antiviral IFNs via the nuclear factor-kappaB(NF-κB)/IFN regulatory factor 3(IRF3)and Janus kinase/signal transducer and activator of transcription(JAK/STAT)signaling pathways.It also reduced IFN-I-induced neutrophil inflammation by inhibiting reactive oxygen species(ROS)and neutrophil extracellular trap(NET)production,and alleviated inflammation in A549 and THP-1 cells via NF-κB/cFOS or mitogen-activated protein kinase(MAPK)/c-Jun signaling.Subsequently,the importance of IFN-Ⅰ/IFN-Ⅲwas verified using IFN alpha receptor 1(Ifnar1)-/-and IFN lambda receptor 1(Ifnlr1)-/-mice.The absence of IFNAR or IFNLR significantly diminished the therapeutic effect of SR against influenza,highlighting its dependence on the IFN-Ⅰ/IFN-Ⅲsystems.Finally,a delayed drug administration experiment in PR8-infected mice revealed that the therapeutic effect of SR heavily relies on early induction of IFN.Overall,our findings offer valuable insights for the clinical utilization of SR,as well as for further exploration of antiviral treatments. 展开更多
关键词 Scutellariae Radix Dual regulation TypeⅠinterferon TypeⅢinterferon Influenza
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Fluorine-induced dual regulation of Co(OH)2 active sites and reactant adsorption behavior for boosted 5-hydroxymethylfurfural electrooxidation performance 认领 引用
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作者 Qin Hu Lijin Yan +7 位作者 Lingwei Feng Mengyuan Ren Chao Juan Chao Huang Siwei Li Alin Cao Zhe Liu Dan Li 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第7期543-555,I0014,共13页
Electrooxidation of 5-hydroxymethylfurfural(HMF)to 2,5-furandicarboxylic acid(FDCA)is pivotal for upgrading biomass to high-value bio-based monomers.However,this process is severely constrained by two critical challen... Electrooxidation of 5-hydroxymethylfurfural(HMF)to 2,5-furandicarboxylic acid(FDCA)is pivotal for upgrading biomass to high-value bio-based monomers.However,this process is severely constrained by two critical challenges:insufficient catalytic active sites and the intrinsic competitive adsorption between HMF and OH-,which collectively restrict reaction kinetics and impede industrial scalability.Herein,we report a fluoride-assisted anodic electric field activation strategy that enables one-step synergistic integration of F-doping into the Co(OH)2 lattice and electrochemical activation.This rational design yields F-doped Co(OH)2/NF electrocatalysts with abundant Co3+/Ni3+active species.The optimized catalyst exhibits a markedly enhanced HMF oxidation reaction(HMFOR)current density of 105 mA cm-2at 1.5 V vs.RHE,corresponding to a 170%enhancement compared with pristine Co(OH)2/NF,along with high 95%FDCA selectivity and excellent stability.Mechanistic investigations reveal that F doping exerts a dual regulatory effect:it not only facilitates the in-situ generation of reactive Co3+/Ni3+active sites but also synergistically modulates the adsorption behavior of HMF and OH-.This synergism effectively mitigates adsorption competition and accelerates the rate-determining steps of HMFOR.Collectively,this work provides a new paradigm for the rational design of high-efficiency electrocatalysts via the synergistic regulation of active sites and adsorption properties,thereby laying a solid foundation for advancing the industrialization of sustainable biomass valorization. 展开更多
关键词 Electrocatalytic oxidation 5-Hydroxymethylfurfural Fluoride doping Adsorption regulation Biomass valorization
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Phase content regulation of P2/O3-type biphasic layered oxides for stable sodium ion storage 认领 引用
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作者 Liang Gao Xue-Yan Wu +7 位作者 Xuheng Jiang Jing-Zhe Wan Jia-Ning Yang Shang-Qi Li Qinfeng Zheng Yixiao Zhang Jie-Sheng Chen Kai-Xue Wang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第4期317-325,I0008,共9页
P2/O3 composite layered transition metal oxides(LTMOs),constructed by elemental doping,markedly improve sodium storage performance.However,the influence of the doped elements,which usually contribute to electrochemica... P2/O3 composite layered transition metal oxides(LTMOs),constructed by elemental doping,markedly improve sodium storage performance.However,the influence of the doped elements,which usually contribute to electrochemical activity,on the electrochemical performance of the resulting biphasic materials could hardly be ruled out.Herein,three compositionally identical P2/O3-Na0.67Fe0.42Li0.08Mn0.45Sn0.05O2materials are synthesized by calcination at 900℃ for 14,12,and 10 h,yielding P2/O3 ratios of approximately 6:1,3:1,and 2:3,respectively.The resulting materials are designated as PO61,PO31,and PO23,respectively.Cycled at 1 C within the voltage range of 2.0-4.5 V,an initial discharge capacity of 118.3 mAh g-1is delivered by PO31,with a retention rate of 81.1%after 100 cycles,significantly outperforming those of PO61(106.8 mAh g-1,65.0%)and PO23(83.9 mAh g-1,61.5%).Systematic investigation of the charge/discharge behaviour reveals that the mitigated phase transition and enhanced cycling performance in these P2/O3 biphasic materials originate from the formation of shorter Fe-O bonds,which promote structural stabilization.This work provides fundamental insights into phase content regulation and advances the development of LTMOs. 展开更多
关键词 Sodium-ion batteries Biphasic materials Layered oxides Phase content regulation Phase transition
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Self-recovery regulation method of rotor unbalance vibration based on GWO-ALQR 认领 引用
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作者 Jiaqiao Lu Ruijie Feng +3 位作者 Xin Pan Meng Zhang Weilong Ma Jinji Gao 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2026年第1期115-124,共10页
Excessive unbalanced vibrations of rotor-bearing systems significantly affect the stability and safety of high-end rotating machinery,such as aero engines,turbo-generators,and high-end machine tools.To realize the on-... Excessive unbalanced vibrations of rotor-bearing systems significantly affect the stability and safety of high-end rotating machinery,such as aero engines,turbo-generators,and high-end machine tools.To realize the on-line self-recovery of unbalanced vibration faults in a rotor system,a self-recovery regulation method based on the grey wolf optimization-adaptive linear quadratic regulator(GWO-ALQR)is proposed.First,a self-recovery regulation system for unbalanced vibrations was constructed,with the state-space equation of the control system obtained and discretized based on the dynamic equation of the rotor-bearing system.Subsequently,a self-recovery regulation method for unbalanced vi-brations based on GWO-ALQR was designed based on the state-space equation.In this method,the parameters of the control system are optimized using grey wolf optimization(GwO),with the working conditions identified on-line.The optimization parameters were selected independently,while the control commands were generated through a linear quadratic regulator(LQR)to control the action of the actuator to achieve self-recovery of the unbalanced vibration.The experimental results indicate that the unbalanced vibration of the rotor system can be restrained below the expected vibration threshold by the self-recovery regulation system based on GWO-ALQR and the final vibration suppression effect can exceed 70%. 展开更多
关键词 Unbalanced vibration Self-recovery regulation Vibration control State-space equation GWO LQR
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Engineered macrophage membrane fusion liposomes carrying siRNA for spatiotemporal regulation of the CCL2/CCR2 axis for cardiac repair 认领 引用
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作者 Xueyi Weng Weiyan Li +16 位作者 Haipeng Tan Zhiqing Pang Jinfeng Gao Shiteng Cai Jing Chen Qiaozi Wang Qiyu Li Youran Li Hongbo Yang Zhengmin Wang Yiwen Tan Yuyuan Fu Chengzhi Han Zheyong Huang Yanan Song Junbo Ge Juying Qian 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第7期553-558,共6页
Excessive and prolonged inflammatory monocyte activity accelerates left ventricular remodeling after myocardial infarction(MI).After myocardial reperfusion,the CCL2/CCR2 axis is considered to be a key chemokine axis t... Excessive and prolonged inflammatory monocyte activity accelerates left ventricular remodeling after myocardial infarction(MI).After myocardial reperfusion,the CCL2/CCR2 axis is considered to be a key chemokine axis that initiates and modulates tissue inflammatory damage.Effectively blocking the CCL2/CCR2 axis can reduce the chemotaxis of inflammatory monocytes to the infarct area,which has important therapeutic value for the repair of myocardium after reperfusion injury(MI/R).Here,we propose a nanoparticle carrying CCL2 silencing short interfering RNA(siRNA),which is prepared by coating a lipid hybrid CCR2-overexprssion macrophage cell membrane on a siRNA-loaded mesoporous silica nanoparticle.The overexpression of CCR2 and adhesion factors on the macrophage membrane improves its targeting ability,directing nanoparticle to the myocardial infarction area of MI/R-induced mice,the overexpress CCR2 in the macrophage cell membrane also adsorb more CCL2.Then by fusing with the cell membrane,si RNA is released into the injured endothelial cells cytoplasm,silencing the expression of CCL2.In vivo administration of the formula blocked CCL2/CCR2 axis,reduce the chemotaxis of inflammatory cells,regulate the immune microenvironment,further decreasing myocardial infarction area and improving cardiac function.Targeted block of CCL2/CCR2 axis represent a new therapeutic intervention for inflammatory disease. 展开更多
关键词 CCL2 CCR2 axis Spatiotemporal regulation siRNA delivery Macrophages Myocardial ischemia-reperfusion injury
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Animal research in the UK:Regulation,implementation,welfare and development of new approach methodologies 认领 引用
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作者 Ewan St.John Smith James Bussell +4 位作者 Maggie Gentry Elliot Lilley Cathy Merry Judy MacArthur Clark William Reynolds 《Animal Models and Experimental Medicine》 CAS CSCD 2026年第5期1056-1062,共7页
Use of animals in biomedical research is still considered essential by many in aca-demia,industry and regulatory authorities.Therefore,it is important that legal,gov-ernance and welfare procedures are in place to ensu... Use of animals in biomedical research is still considered essential by many in aca-demia,industry and regulatory authorities.Therefore,it is important that legal,gov-ernance and welfare procedures are in place to ensure that only necessary procedures using animals are carried out and that this occurs within a framework with animal welfare at its core.Animal research in the United Kingdom is conducted under the Animals(Scientific Procedures)Act 1986 and animal research in the United Kingdom has long been seen as a flag bearer for high quality-high welfare research.An example of the leading role taken in supporting animal welfare in research was establishment of the National Centre for the Replacement,Refinement and Reduction of Animals in Research(NC3Rs)to support reducing the scale and impact of animal research.Here,we provide an overview of governance and licensing procedures of animal research in the United Kingdom,coupled with explanations of how excellent welfare underpins high quality research,and examine the development of new approach methodologies. 展开更多
关键词 3Rs New approach methodologies Regulation Welfare
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