The soil-water retention and soil shrinkage characteristics are both crucial constitutive relations for unsaturated soils.Although existing research has explored the correlation between these two characteristics to so...The soil-water retention and soil shrinkage characteristics are both crucial constitutive relations for unsaturated soils.Although existing research has explored the correlation between these two characteristics to some extent,the underlying mechanisms remain inadequately investigated.To investigate the correlation between the soil-water retention and soil shrinkage behavior,a series of soil-water retention and soil shrinkage tests is performed on compacted clays over a wide suction range(0–367 MPa).The test results show that the pore water in compacted clays is first expelled from large pores in low suction range.The drainage of pore water at low suctions is predominantly responsible for the phase of structural shrinkage in the soil shrinkage curve.The consistency between the characteristic transitional water contents in the soil shrinkage curve(SSC)and the inflection points in the soil-water retention curve(SWRC)is identified for all the compacted clays.The bimodal pore-size distributions(PSDs)of different clayey soils are obtained using the mercury intrusion porosimetry.The bimodal pore-size distribution characterization is the intrinsic factor in shaping the bimodal morphology in the SWRC over a wide suction range.The low proportion of micropores in clays is responsible to the indistinct zero-shrinkage stage of the SSC.The microstructure measured by the scanning electron microscope indicates the manifestation of aggregation effects during desaturation process.The results demonstrate that soil shrinkage is primarily caused by the contraction of inter-aggregate pores,rather than the evolution of intra-aggregate pores.The findings can greatly enhance the understanding of the soil-water retention and mechanical behavior of compacted clays in varying water content conditions.展开更多
Bacterial cells are widely accepted as nucleation sites for calcium carbonate precipitation in biomineralization based on the Microbially Induced Carbonate Precipitation(MICP)process.For MICP-based insitu biotreatment...Bacterial cells are widely accepted as nucleation sites for calcium carbonate precipitation in biomineralization based on the Microbially Induced Carbonate Precipitation(MICP)process.For MICP-based insitu biotreatment,the firstproblem to be solved is how to introduce and retain the bacterial cells in the soil,which involves the migration and retention of bacterial cells during the biogrouting process.Soil particle size,a key factor in determining pore throat size,can have a significanteffect on the migration and retention of bacterial cells in the soil and therefore on biomineralization.To investigate the effect of particle size on the migration and retention of bacterial cells in sand and its biomineralization,two sets of tests were carried out in this study,including percolation tests and sand column treatment tests.Soil urease activity(definedas urease activity per unit mass of soil)and calcium carbonate content of the biomineralized sand were measured to comprehensively assess the migration and retention of bacterial cells in the sand.The results indicate that sands with a particle size smaller than 0.25 mmwould inhibit the migration of bacteria in the sand,resulting in a nonuniform distribution of precipitated calcium carbonate and a low strength enhancement of biomineralization.On the other hand,sands with a particle size larger than 1.18 mm are unfavorable for retaining bacterial cells in the sand,resulting in low calcium conversion efficiency.Meanwhile,particle size would also affect the formation of effective calcium carbonate through interparticle contact number and interparticle pore size,and thus biomineralization.展开更多
In tailings permeated by leachate containing thallium(Tl),manganese oxides(MnO x)are recognized as critical substances in immobilizing Tl and preventing its further migration into groundwater.However,dissolved Mn(...In tailings permeated by leachate containing thallium(Tl),manganese oxides(MnO x)are recognized as critical substances in immobilizing Tl and preventing its further migration into groundwater.However,dissolved Mn(Ⅱ)and Fe(Ⅲ)also exist in micro-oxic environments.The effects and mechanisms of the increased levels of these coexisting ions,driven by environmental processes such as rainfall leaching,on Tl(Ⅰ)retention remain largely unclear.This study established two systems using natural manganese sand and limestone sand as porous media,demonstrating that the elevated Mn(Ⅱ)/Fe(Ⅲ)loadings weakened Tl(Ⅰ)retention.Redundancy analysis identified media type and depth as primary factors shaping microbial communities,which subsequently influenced Tl(Ⅰ)immobilization.Manganese sand exhibited superior recovery capacity compared to limestone sand under higher Mn(Ⅱ)and Fe(Ⅲ)loadings.Co-occurrence network analyses revealed that media-microorganism suitability governs microbial community structure and heavy metal retention efficiency.Hydraulic impact and dissolved organic/inorganic cations reduced MnO x content,while the higher retention capacity of manganese sand was attributed to the presence of microorganisms with higher activity and abundance,as well as an increased abundance of microbial-generated MnO_( x).This study offers novel insights into the mechanisms underlying Tl(Ⅰ)retention in tailings,which is crucial for comprehending its environmental fate.展开更多
Developing hydrogel electrolytes that simultaneously overcome the critical challenges of rapid dehydration,narrow operational temperature windows,poor interfacial adhesion,and irreparable mechanical damage remains an ...Developing hydrogel electrolytes that simultaneously overcome the critical challenges of rapid dehydration,narrow operational temperature windows,poor interfacial adhesion,and irreparable mechanical damage remains an urgent need for reliable supercapacitors,since these challenges significantly compromise their cycling stability.Herein,a versatile biomass hydrogel electrolyte(PSBGD-Li)is developed through dynamic borate ester crosslinking between peach gum polysaccharide and starch,integrating exceptional water retention(≥66 days,92.01%retention),wide temperature adaptability(−30℃ to 50℃),rapid subzero self-healing(99.4%recovery in 5 min at−30℃),high ionic conductivity(34.71 mS cm⁻¹ at 25℃;9.22 mS cm⁻¹ at−30℃),and excellent mechanical robustness(>1600% strain without breakage,30.7 kPa interfacial adhesion).Supercapacitors equipped with PSBGD-Li exhibit superior all-climate electrochemical cycling stability,delivering a high specific capacitance of 216 F g⁻¹ at 25℃ with 98.6%capacitance retention after 15000 cycles.Remarkably,they maintain outstanding temperature reliability,retaining 99.2%capacitance at −30℃ and 92.4% at 50℃,while preserving >99% specific capacitance after sequential thermal cycling between −30℃ and 50℃.Flexible supercapacitors also maintain stable electrochemical performance after repeated bending or cutting/healing cycles,highlighting significant potential for developing green,temperature-tolerant,reliable flexible energy storage in extreme environments.展开更多
BACKGROUND Rectal foreign bodies(RFBs),mostly due to self-insertion for sexual pleasure,are occasionally encountered in emergency departments.They are more common in young male patients,and because patients often dela...BACKGROUND Rectal foreign bodies(RFBs),mostly due to self-insertion for sexual pleasure,are occasionally encountered in emergency departments.They are more common in young male patients,and because patients often delay seeking medical attention due to embarrassment,complications such as perforation and peritonitis may be present at diagnosis.Emergency physicians must remain mindful of potential RFB insertion and conduct history-taking and physical examinations with sensitivity to patient embarrassment.Reports of penetrating peritonitis caused by long-term RFB retention are rare.CASE SUMMARY A 16-year-old male experienced persistent fever of approximately 38°C for 35 days.Although antipyretics and antibiotics were prescribed at a local clinic,his symptoms did not improve.Later,he disclosed that his condition had worsened after inserting a smartphone stand into his rectum 35 days before for sexual gratification,and he was referred to our hospital.Upon arrival,his vital signs were stable,and mild tenderness was noted in the left lower abdomen.Laboratory tests revealed leukocytosis and elevated C-reactive protein levels(5.21 mg/dL).Abdominal computed tomography revealed a spring-like foreign body and a large amount of fecal material in the rectum.Endoscopic removal was unsuccessful;therefore,laparotomy was performed for object extraction.Intraoperatively,the rectum was found to have perforated into the retroperitoneal cavity.The postoperative course was uneventful,and the patient was discharged 11 days after admission.CONCLUSION We report a case of penetrating peritonitis after long-term RFB retention,without an acute abdomen,because the perforation was retroperitoneal.展开更多
Urban blue-green infrastructure(BGI)plays a significant role in regulating stormwater management and mitigating urban flooding.However,the effectiveness of urban BGI in mitigating surface runoff remains insufficiently...Urban blue-green infrastructure(BGI)plays a significant role in regulating stormwater management and mitigating urban flooding.However,the effectiveness of urban BGI in mitigating surface runoff remains insufficiently explored,particularly in densely populated,flood-prone cities.This study presents an integrated geospatial framework to evaluate the runoff retention capacity of urban BGI and their associated flood mitigation services in Kolkata City,India.The Integrated Valuation of Ecosystem Services and Trade-Offs(InVEST)-Urban Flood Risk Mitigation(UFRM)model was applied to estimate the potential runoff generation and retention under two rainfall scenarios in Kolkata City.The model incorporated land use and land cover types,hydrological soil groups,and rainfall inputs to simulate spatial runoff patterns and runoff retention potential across different urban micro-watersheds.Flood mitigation services provided by BGI were quantified in terms of runoff retention capacity and flood volume generation.The results show that urban BGI provides substantial runoff retention capacity,with tree-covered lands and herbaceous wetlands retaining 45.0o%-60.0o%more runoff than impervious surfaces.Spatial analysis indicates that regions with permeable surfaces and dense vegetation cover enhance infiltration and water absorption,thereby demonstrating the hydrological effectiveness of BGI.The InVEST-UFRM results were validated with Synthetic Aperture Radar-derived flood data and machine learning-based models,including Random Forest(RF)model and eXtreme Gradient Boosting(XGBoost)model,with the area under curve scores(XGBoost model:0.73;RF model:0.70)confirming the model’s ability to predict flood risk.This integrated framework provides a practical tool for assessing the flood mitigation potential of BGI and offers practical insights for urban planners and policy-makers seeking to improve urban flood management and support more resilient urban landscapes.展开更多
BACKGROUND Early postoperative edema and ascites after liver resection are common;however,the endocrine drivers of water retention are not fully defined.Arginine vasopressin(AVP)promotes antidiuresis via V2-mediated a...BACKGROUND Early postoperative edema and ascites after liver resection are common;however,the endocrine drivers of water retention are not fully defined.Arginine vasopressin(AVP)promotes antidiuresis via V2-mediated aquaporin trafficking,whereas the renin-angiotensin-aldosterone system primarily modulates sodium handling.Differences in postoperative trajectories and their relationship to early fluid retention have not been clarified in patients undergoing liver resection.AIM To examine postoperative changes in plasma AVP and plasma aldosterone concentration(PAC)after liver resection,and association with fluid retention.METHODS We conducted a prospective cohort study of adults undergoing elective liver resection at a tertiary center.Blood samples were collected preoperatively,immediately post-resection,and on postoperative days(POD)1,2,3,and 5.The primary objective was characterizing postoperative dynamics of AVP and PAC.Secondary objectives evaluated their temporal alignment with early fluid retention(body weight,urine output during POD 1-3)and compared hormonal profiles between major and minor resections.Analyses used trajectory and timebased comparisons by resection extent.RESULTS AVP increased sharply immediately after resection and remained above the preoperative baseline through POD 3,showing the most pronounced and sustained elevation after major liver resection.In contrast,PAC showed a transient postoperative increase that returned to near-baseline levels by POD 2.The period of elevated AVP closely matched the time frame during which early postoperative fluid retention was most evident,as indicated by greater short-term weight gain and reduced urine output.These patterns were consistent across sensitivity analyses and showed similar directional trends in subgroup comparisons based on resection extent.CONCLUSION AVP remains elevated longer than aldosterone and coincides with early fluid retention,particularly after major resection.Vasopressin-driven antidiuresis may be important in postoperative water retention.展开更多
Oral leukoplakia(OLK)is a common and representative malignant disease of oral mucosa,and possess a higher risk of cancer.Compared with traditional surgical treatment,photodynamic therapy(PDT)has great potential in OLK...Oral leukoplakia(OLK)is a common and representative malignant disease of oral mucosa,and possess a higher risk of cancer.Compared with traditional surgical treatment,photodynamic therapy(PDT)has great potential in OLK treatment,due to its advantages of minimally invasiveness and low toxic side effects.However,traditional photosensitizer administration suffers from short retention time due to the fluid environment of saliva and extensive tongue movement,leading to poor drug(photosensitizer)utilization and limited therapeutic outcome.To address such issue,here a photosensitive guanosine(G)-based hydrogel system(G@GQD)was constructed,in which graphene quantum dots(GQDs)featuring high photosensitization activity was loaded through three dimensional(3D)fiber network physical encapsulation.The favorable adhesion of the G@GQD hydrogel on the tongue,together with sustained GQDs release,significantly enhanced the retention of GQDs within the oral cavity.As a result,G@GQD hydrogel could continuously generate high levels of reactive oxygen species(ROS)under irradiation,demonstrating a sustained therapeutic efficiency in vitro.Compared with free GQDs,G@GQD exhibited significantly improved PDT efficiency in treating 4-nitroquinoline 1-oxide(4-NQO)-induced OLK animals.This study presented a promising strategy in overcoming the drug retention barrier that caused by saliva and tongue movement,which has far-reaching significance for the future PDT therapies.展开更多
The soil-water retention curve(SWRC)plays a pivotal role in understanding water movement across numerous geological engineering applications.Despite significant advancements in theoretical modeling approaches,accurate...The soil-water retention curve(SWRC)plays a pivotal role in understanding water movement across numerous geological engineering applications.Despite significant advancements in theoretical modeling approaches,accurate prediction of SWRCs remains challenging due to the inherently sparse and incomplete nature of site-specific data.This study compiled a comprehensive dataset of SWRCs spanning a wide suction range from various published literature sources.Based on this dataset,multiple machine learning(ML)algorithms were employed to predict SWRCs.The performance of each algorithm was evaluated and ranked using four statistical indicators that quantify simulation accuracy.Feature importance analysis was subsequently conducted to reduce dimensionality by eliminating weakly correlated variables,thereby enhancing both model adaptability and computational efficiency.Following dimensionality reduction,a base learner pool was constructed and integrated through stacked generalization to create a multi-algorithm ensemble model.The proposed stacked model demonstrated robust performance in simulating SWRCs across diverse soil types,using only basic physical properties as inputs,achieving accuracy comparable to or marginally superior to the LightGBM model.The principal advantage of the stacked approach lies in its substantially improved accuracy within high suction ranges,effectively overcoming the limitations observed in LightGBM and enhancing the estimation under these conditions.This study provides valuable insights for researchers evaluating SWRCs through ML algorithms and demonstrates the potential of ensemble techniques in geotechnical prediction tasks.展开更多
Sand dust belts span approximately one-fifth of the global land surface.In these regions,dust tends to settle on vegetation surfaces,altering the observed reflectance and affecting remote sensing detections.To enhance...Sand dust belts span approximately one-fifth of the global land surface.In these regions,dust tends to settle on vegetation surfaces,altering the observed reflectance and affecting remote sensing detections.To enhance the accuracy of maize growth monitoring in dust-affected regions,this study aims to quantify the effect of sand dust retention on maize during the tasseling stage in the Kashgar Prefecture,Xinjiang Uygur Autonomous Region,China,by analyzing changes in canopy reflectance and vegetation indices.First,field sampling was conducted to measure the key canopy structure parameters and dust retention levels of maize,and laboratory spectral measurements were performed on leaf spectral properties under gradient dust retention.The measured data were then used to drive the LargE-Scale remote sensing data and image Simulation framework(LESS)model for simulating realistic maize canopy spectra across different dust levels,with validation against Sentinel-2 imagery.Second,on the basis of the simulated and satellite-derived spectra,the dust resistance of 36 common vegetation indices was systematically evaluated,and new robust dust-resistant indices were developed.The results showed that compared with dust-free maize,the canopy reflectance of dust-retained maize followed an increase–decrease–increase pattern,with critical turning points at 735 and 1325 nm.The maximum reflectance difference of–0.11755(change rate:29.002%)occurred within the 735–1325 nm range at 24 g/m2dust retention,and the minimum reflectance difference of 0.04285(change rate:148.950%)was observed in the 350–735 nm range under the same dust retention level.Among the 36 vegetation indices,only the global environment monitoring index(GEMI)and the ratio of transformed chlorophyll absorption in reflectance index to optimized soil-adjusted vegetation index(TCARI/OSAVI)exhibited dust resistance,with GEMI being effective below 6 g/m2and TCARI/OSAVI remaining stable across all levels(average ratio:0.970).The newly developed indices in this study,(RE3–RE2)/(NIR–RE2),(RE3–RE2)/(RE4–RE2),and(NIR–RE2)/(RE4–RE2),retained values within the predefined dust-resistant range over the full dust retention levels of 0–24 g/m2,thus showing a more stable dust resistance compared with the commonly used 36 vegetation indices.Specially,(RE3–RE2)/(RE4–RE2)performed the most robustly in Sentinel-2 imagery,that is,58.020%of pixels were within the dust-resistant range,and an average ratio of 0.937 was obtained for the original-spectra index.This study provides a scientific basis for crop monitoring and management in dust-affected regions.展开更多
Higher prevalence of sporadic Alzheimer’s disease in women:Alzheimer’s disease(AD)is a progressive neurodegenerative disorder caused by the accumulation of amyloid-β(Aβ)plaques and Tau neurofibrillary tangles in t...Higher prevalence of sporadic Alzheimer’s disease in women:Alzheimer’s disease(AD)is a progressive neurodegenerative disorder caused by the accumulation of amyloid-β(Aβ)plaques and Tau neurofibrillary tangles in the affected brain regions.The clearance of these pathological protein aggregates by microglia can trigger excessive neuroinflammation,which contributes to brain atrophy.AD exhibits clinical heterogeneity and is characterized by highly complex,multifactorial etiology(Lopez-Lee et al.,2024).展开更多
The deployment of specialized language models in resource-constrained edge environments(≤1 B parameters,≤2 GB memory,≤100 ms latency)faces a critical challenge:Supervised Fine-Tuning(SFT)achieves domain expertise b...The deployment of specialized language models in resource-constrained edge environments(≤1 B parameters,≤2 GB memory,≤100 ms latency)faces a critical challenge:Supervised Fine-Tuning(SFT)achieves domain expertise but suffers from irreversible catastrophic forgetting,while traditional Low-Rank Adaptation(LoRA)with conservative ranks(r≤64)often underperforms due to insufficient adaptation capacity.This work introduces H-LoRA(High-Rank LoRA)for edge-deployable models and establishes a fundamental distinction between destructive forgetting and controllable knowledge retention.Through comprehensive experiments on compact models(0.12 B Minimind and Qwen-0.5 B)across three domains(Human Resources,Medical,Mathematics)using 29,647 samples,we demonstrate that while both SFT and H-LoRA exhibit general capability degradation,they differ fundamentally:SFT completely destroys the original knowledge structure(1%topic retention),while H-LoRA maintains knowledge integrity with 90%topic retention—an 89 percentage point improvement—enabling post-deployment capability recovery.H-LoRA employs simplified scaling and strategic high-rank adaptation at approximately two-thirds of the model’s hidden dimension(r=512 for d=768),achieving SFT-level domain performance(99.81%precision)with 5×greater parameter efficiency(20.35%trainable parameters)and robust cross-domain generalization(93.5±6.8%average precision).In addition,H-LoRA reduces over-the-air(OTA)update size from 1.4 GB to 96 MB(≈93%),enabling practical and frequent deployment of specialized models in bandwidth-limited edge environments.Beyond demonstrating effectiveness,this work establishes the first comprehensive framework for characterizing specialization-retention trade-offs in parameter-efficient fine-tuning,providing practical guidance for method selection in real-world deployments.展开更多
Quantifying spatial heterogeneity in soil water retention properties(SWRP)is crucial for enhancing the accuracy of hydrogeological simulations.However,studies on the spatial heterogeneity of SWRP in the Chinese Loess ...Quantifying spatial heterogeneity in soil water retention properties(SWRP)is crucial for enhancing the accuracy of hydrogeological simulations.However,studies on the spatial heterogeneity of SWRP in the Chinese Loess Plateau(CLP)remain scarce,especially at the vertical scale.We conducted laboratory tests on undisturbed loess cores collected from boreholes in CLP to analyze soil physical parameters(SPPs)and SWRP.Measured soil water characteristic curves(SWCCs)were fitted to the Brooks-Corey(BC),Fredlund-Xing(FX),and van Genuchten(vG)models.It was revealed that the FX and vG models outperformed the BC model.The geostatistical analysis identified the Gaussian model as optimal for describing the semivariograms of both SPPs and SWCC fitting parameters(FPs).Strikingly,over 90%of these parameters exhibited strong vertical spatial dependence,with an average autocorrelation length of 213.878 cm for SPPs and 320.678 cm for FPs.Moreover,SWRP was found to be significantly influenced by both SPPs and the vertical position relative to the loess ridge slope surface.Parameters near the ridge slope surface showed significantly degraded spatial dependence.These findings provide valuable insights for parameterizing the spatial heterogeneity of soil water retention properties,which are beneficial for hydrogeological modelling in shallow CLP loess strata.展开更多
Hydrosilanes,important reagents in synthesis,typically undergo Si−H bond reactions,with selective functionalization of adjacent C−H bonds in the presence of Si−H remaining a major challenge.In this work,we present a d...Hydrosilanes,important reagents in synthesis,typically undergo Si−H bond reactions,with selective functionalization of adjacent C−H bonds in the presence of Si−H remaining a major challenge.In this work,we present a dual‑metal photocatalytic strategy that achieves a long‑standing selectivity goal:the direct radical C−H functionalization of hydrosilanes while completely preserving the reactive Si−H bond.Unlike classical transformations where hydrosilanes act solely as reductants,our method leverages their inherentβ‑silicon effect to activate adjacent C(sp3)−H bonds.By employing a cooperative system of an Fe(III)chlorideetrabutylammonium decatungstate photocatalyst and a Cu(I)cocatalyst under light,we facilitate a chemoselective hydrogen atom transfer(HAT)and radical cross‑coupling withα‑imino esters.The reaction demonstrates broad scope,accommodating a wide range ofα‑imino esters bearing diverse electronic and steric properties,as well as various alkyl‑,aryl‑,and heterocycle‑substituted silanes.Remarkably,the process exhibits excellent selectivity for theβ‑C−H bond even in substrates containing multiple Si−H bonds,with no detectable hydrosilylation byproducts.The retained Si−H functionality serves as a versatile handle for further derivatization,as demonstrated through one‑pot etherification and catalytic hydrosilylation of alkenes and alkynes.Mechanistic studies,including light‑switching experiments,radical trapping and the isolation of self‑coupling side product from theα‑imino ester substrate,support a pathway involving ligand‑to‑metal charge transfer(LMCT)from photoexcited Fe(III)to generate chlorine radicals,subsequent hydrogen abstraction to formβ‑silyl carbon radicals,and their ultimate cross‑coupling with imine‑derivedα‑amino radicals.This work establishes a platform for the modular editing of hydrosilane frameworks,introducing a valuable disconnection for synthesizing functionally dense organosilicon molecules.展开更多
This review summarizes the definition and classification,etiology and pathogenesis of postpartum urinary retention,as well as the application of Traditional Chinese Medicine(TCM)nursing techniques in its prevention an...This review summarizes the definition and classification,etiology and pathogenesis of postpartum urinary retention,as well as the application of Traditional Chinese Medicine(TCM)nursing techniques in its prevention and treatment.It also identifies the limitations and prospects of TCM nursing techniques in managing postpartum urinary retention,aiming to provide a reference for the clinical application and future research of TCM nursing techniques regarding this condition.展开更多
To elucidate the adsorption characteristics and retention mechanisms of fracturing fluids in diverse clay minerals,we conducted on-line nuclear magnetic resonance(NMR)and atomic force microscopy(AFM)experiments.The de...To elucidate the adsorption characteristics and retention mechanisms of fracturing fluids in diverse clay minerals,we conducted on-line nuclear magnetic resonance(NMR)and atomic force microscopy(AFM)experiments.The depth and extent of solid phase damage are determined by the ratio between the size of fine fractions in fracturing fluid residue and the pore-throat size in experiments.Poor physical properties(K0.5 mD)combined with a scattered distribution of retained fracturing fluid is associated with high gas phase recovery permeability,whereas a continuous sheet-like distribution results in low recovery permeability.The expansive surface area and presence of filamentous illite minerals facilitate the multiple winding and adsorption of fracturing fluids,demonstrating strong hydrogen-bonding,multi-layering and multiple adsorption properties.The geological characteristics of the main gas formations exhibit significant variation,and the severity of damage caused by fracturing fluids occurs in diverse sequences.To address this issue,a differentiated strategy for optimizing frac-turing fluids has been proposed.展开更多
As a widely used fertilizer,urea significantly promotes the leaching of dissolved organic nitrogen(DON)in soils and aggravates nitrogen contamination in groundwater.Clayminerals are considered the most important facto...As a widely used fertilizer,urea significantly promotes the leaching of dissolved organic nitrogen(DON)in soils and aggravates nitrogen contamination in groundwater.Clayminerals are considered the most important factor in retaining DON.However,the effect of urea on the retention of DON with different molecular weights by clay minerals is unknown.In this study,the retention of both low-molecular weight DON(LMWD)and high-molecular weight DON(HMWD)by clay minerals in the presence of urea was investigated.For this purpose,batch adsorption and soil column leaching experiments,characterization analysis(Fourier transform infrared spectroscopy X-ray diffraction,and X-ray photoelectron spectroscopy),and molecular dynamics simulations were carried out.Urea had a positive effect on the adsorption of LMWD,whereas a competitive effect existed for the adsorption of HMWD.The dominant interactions among DON,urea,and clay minerals included H-bonding,ligand exchange,and cation exchange.The urea was preferentially adsorbed on clay minerals and formed a complex,which provided more adsorption sites to LMWD and only a few to HMWD.The presence of urea increased the retention of LMWD and decreased the retention of HMWD in clay minerals.The retention capacity of LMWD increased by 6.9%–12.8%,while that of HMWD decreased by 6.7%–53.1%.These findings suggest that LMWD tended to be trapped in soils,while HMWD was prone to be leached into groundwater,which can be used to evaluate the leaching of DON from soil to groundwater.展开更多
Gastric retention is a common complication in individuals receiving enteral nutrition(EN)via a nasogastric tube,increasing the risk of aspiration pneumonia and causing unnecessary interruptions in nutritional support....Gastric retention is a common complication in individuals receiving enteral nutrition(EN)via a nasogastric tube,increasing the risk of aspiration pneumonia and causing unnecessary interruptions in nutritional support.Given its clinical significance,establishing effective,evidence-based,and standardized manage-ment strategies is essential for bettering patient outcomes and mitigating compli-cations.This review systematically synthesized the diagnostic criteria,assessment methods,influencing factors,management procedures,and intervention strategies for gastric retention in EN patients.Although no universal consensus exists re-garding gastric residual volume(GRV)thresholds,evidence indicates that EN can continue at high GRV levels in the absence of gastrointestinal symptoms.Bedside ultrasound emerged as a non-invasive,and precise method GRV assessment,offering potential to standardize clinical practice.Key risk factors for gastric retention include neurological disorders and EN infusion rates exceeding 100 mL/h.Effective management strategies encompass non-pharmacological inter-ventions,pharmacological agents,and traditional Chinese medicine(TCM)the-rapies.This review underscored the need for integrated,multi-modal manage-ment strategies and recommended the adoption of bedside ultrasound and stan-dardized protocols to optimize EN delivery and improve patient outcomes.Large-scale,multicenter clinical trials should be a priority for future investigation to verify the effectiveness of TCM therapies and develop personalized intervention plans for high-risk patients.展开更多
Objectives:This study aimed to explore the voices of Indonesian migrant nurses on their retention in Japanese healthcare facilities.Methods:A descriptive qualitative study was conducted between June and September 2023...Objectives:This study aimed to explore the voices of Indonesian migrant nurses on their retention in Japanese healthcare facilities.Methods:A descriptive qualitative study was conducted between June and September 2023.The snowball sampling method was utilized to recruit 22 Indonesian nurses working in healthcare facilities in seven prefectures of Japan.Semi-structured interviews were conducted based on their shared experiences.All interview data were audio-recorded,transcribed verbatim,and analyzed using thematic analysis.Results:Six prominent themes and 15 subthemes emerged:1)organizational factors(caring leader,involvement in decision making,career development,and participation in training);2)social support systems(group support,colleagues support and friend support);3)individual drive(lifelong learning and persistent);4)national policies(government support in public service and flexibility in finding a comfortable placement);5)family factors(positive support of child education and development and maintaining relationship with spouse);and 6)economic factors(staying due to high salary and increasing income streams).Conclusions:Retention of Indonesian migrant nurses in Japan is a multifaceted challenge that hinges on various interconnected factors.This study has gone some way toward enhancing our understanding of international nurse retention in the receiving countries.Corresponding supports at the individual,family,organizational,economic,social,and national policy levels should be considered to keep them in their destination countries.展开更多
For the purpose of satisfying high demands for taste,color,flavor,and storage of meat products,water retention agents(WRAs)play an important role.Phosphate has been widely used as an attractive functional material for...For the purpose of satisfying high demands for taste,color,flavor,and storage of meat products,water retention agents(WRAs)play an important role.Phosphate has been widely used as an attractive functional material for water retention in current practical applications.However,excessive phosphate addition and longterm consumption may be harmful impacts on health and the environment.Therefore,it is vital to develop safe and efficient phosphate-free WRAs for further improving water-holding capacity(WHC)efficacy and edible safety,especially in meat products.In particular,sugar water retention agents(SWRAs)are increasingly popular because of their perfect safety,excellent WHC,and superior biological properties.This review discusses the inducements and mechanisms underlying water loss in meat products.In addition,we focused on the research progresses and related mechanisms of SWRAs in the WHC of meat products and its unique biological functions,as well as the extraction technology.Finally,the future application and development of SWRA were prospected.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.52238007 and 52378354)the Research Fund Key Laboratory of Geomechanics and Geotechnical Engineering Safety,Chinese Academy of Sciences(Grant No.JBGS2405)the Science and Technology Program of Guizhou Department of Transportation(Grant No.2023-122-035).
摘要The soil-water retention and soil shrinkage characteristics are both crucial constitutive relations for unsaturated soils.Although existing research has explored the correlation between these two characteristics to some extent,the underlying mechanisms remain inadequately investigated.To investigate the correlation between the soil-water retention and soil shrinkage behavior,a series of soil-water retention and soil shrinkage tests is performed on compacted clays over a wide suction range(0–367 MPa).The test results show that the pore water in compacted clays is first expelled from large pores in low suction range.The drainage of pore water at low suctions is predominantly responsible for the phase of structural shrinkage in the soil shrinkage curve.The consistency between the characteristic transitional water contents in the soil shrinkage curve(SSC)and the inflection points in the soil-water retention curve(SWRC)is identified for all the compacted clays.The bimodal pore-size distributions(PSDs)of different clayey soils are obtained using the mercury intrusion porosimetry.The bimodal pore-size distribution characterization is the intrinsic factor in shaping the bimodal morphology in the SWRC over a wide suction range.The low proportion of micropores in clays is responsible to the indistinct zero-shrinkage stage of the SSC.The microstructure measured by the scanning electron microscope indicates the manifestation of aggregation effects during desaturation process.The results demonstrate that soil shrinkage is primarily caused by the contraction of inter-aggregate pores,rather than the evolution of intra-aggregate pores.The findings can greatly enhance the understanding of the soil-water retention and mechanical behavior of compacted clays in varying water content conditions.
基金support by the National Natural Science Foundation of China(NSFC)(Grant Nos.52178319,42477160,52338007).
摘要Bacterial cells are widely accepted as nucleation sites for calcium carbonate precipitation in biomineralization based on the Microbially Induced Carbonate Precipitation(MICP)process.For MICP-based insitu biotreatment,the firstproblem to be solved is how to introduce and retain the bacterial cells in the soil,which involves the migration and retention of bacterial cells during the biogrouting process.Soil particle size,a key factor in determining pore throat size,can have a significanteffect on the migration and retention of bacterial cells in the soil and therefore on biomineralization.To investigate the effect of particle size on the migration and retention of bacterial cells in sand and its biomineralization,two sets of tests were carried out in this study,including percolation tests and sand column treatment tests.Soil urease activity(definedas urease activity per unit mass of soil)and calcium carbonate content of the biomineralized sand were measured to comprehensively assess the migration and retention of bacterial cells in the sand.The results indicate that sands with a particle size smaller than 0.25 mmwould inhibit the migration of bacteria in the sand,resulting in a nonuniform distribution of precipitated calcium carbonate and a low strength enhancement of biomineralization.On the other hand,sands with a particle size larger than 1.18 mm are unfavorable for retaining bacterial cells in the sand,resulting in low calcium conversion efficiency.Meanwhile,particle size would also affect the formation of effective calcium carbonate through interparticle contact number and interparticle pore size,and thus biomineralization.
基金supported by the National Natural Science Foundation of China(No.52422005)the Natural Science Foundation of Chongqing,China(No.CSTB2025NSCQ-JQX0029).
摘要In tailings permeated by leachate containing thallium(Tl),manganese oxides(MnO x)are recognized as critical substances in immobilizing Tl and preventing its further migration into groundwater.However,dissolved Mn(Ⅱ)and Fe(Ⅲ)also exist in micro-oxic environments.The effects and mechanisms of the increased levels of these coexisting ions,driven by environmental processes such as rainfall leaching,on Tl(Ⅰ)retention remain largely unclear.This study established two systems using natural manganese sand and limestone sand as porous media,demonstrating that the elevated Mn(Ⅱ)/Fe(Ⅲ)loadings weakened Tl(Ⅰ)retention.Redundancy analysis identified media type and depth as primary factors shaping microbial communities,which subsequently influenced Tl(Ⅰ)immobilization.Manganese sand exhibited superior recovery capacity compared to limestone sand under higher Mn(Ⅱ)and Fe(Ⅲ)loadings.Co-occurrence network analyses revealed that media-microorganism suitability governs microbial community structure and heavy metal retention efficiency.Hydraulic impact and dissolved organic/inorganic cations reduced MnO x content,while the higher retention capacity of manganese sand was attributed to the presence of microorganisms with higher activity and abundance,as well as an increased abundance of microbial-generated MnO_( x).This study offers novel insights into the mechanisms underlying Tl(Ⅰ)retention in tailings,which is crucial for comprehending its environmental fate.
基金financial support from the Natural Science Foundation of Guangdong Province (2024A1515012372)the National Natural Science Foundation of China (21875144)the Shenzhen Science and Technology Research Grant (JCYJ20200109105003940)
摘要Developing hydrogel electrolytes that simultaneously overcome the critical challenges of rapid dehydration,narrow operational temperature windows,poor interfacial adhesion,and irreparable mechanical damage remains an urgent need for reliable supercapacitors,since these challenges significantly compromise their cycling stability.Herein,a versatile biomass hydrogel electrolyte(PSBGD-Li)is developed through dynamic borate ester crosslinking between peach gum polysaccharide and starch,integrating exceptional water retention(≥66 days,92.01%retention),wide temperature adaptability(−30℃ to 50℃),rapid subzero self-healing(99.4%recovery in 5 min at−30℃),high ionic conductivity(34.71 mS cm⁻¹ at 25℃;9.22 mS cm⁻¹ at−30℃),and excellent mechanical robustness(>1600% strain without breakage,30.7 kPa interfacial adhesion).Supercapacitors equipped with PSBGD-Li exhibit superior all-climate electrochemical cycling stability,delivering a high specific capacitance of 216 F g⁻¹ at 25℃ with 98.6%capacitance retention after 15000 cycles.Remarkably,they maintain outstanding temperature reliability,retaining 99.2%capacitance at −30℃ and 92.4% at 50℃,while preserving >99% specific capacitance after sequential thermal cycling between −30℃ and 50℃.Flexible supercapacitors also maintain stable electrochemical performance after repeated bending or cutting/healing cycles,highlighting significant potential for developing green,temperature-tolerant,reliable flexible energy storage in extreme environments.
摘要BACKGROUND Rectal foreign bodies(RFBs),mostly due to self-insertion for sexual pleasure,are occasionally encountered in emergency departments.They are more common in young male patients,and because patients often delay seeking medical attention due to embarrassment,complications such as perforation and peritonitis may be present at diagnosis.Emergency physicians must remain mindful of potential RFB insertion and conduct history-taking and physical examinations with sensitivity to patient embarrassment.Reports of penetrating peritonitis caused by long-term RFB retention are rare.CASE SUMMARY A 16-year-old male experienced persistent fever of approximately 38°C for 35 days.Although antipyretics and antibiotics were prescribed at a local clinic,his symptoms did not improve.Later,he disclosed that his condition had worsened after inserting a smartphone stand into his rectum 35 days before for sexual gratification,and he was referred to our hospital.Upon arrival,his vital signs were stable,and mild tenderness was noted in the left lower abdomen.Laboratory tests revealed leukocytosis and elevated C-reactive protein levels(5.21 mg/dL).Abdominal computed tomography revealed a spring-like foreign body and a large amount of fecal material in the rectum.Endoscopic removal was unsuccessful;therefore,laparotomy was performed for object extraction.Intraoperatively,the rectum was found to have perforated into the retroperitoneal cavity.The postoperative course was uneventful,and the patient was discharged 11 days after admission.CONCLUSION We report a case of penetrating peritonitis after long-term RFB retention,without an acute abdomen,because the perforation was retroperitoneal.
基金the financial support in the form of a Junior Research Fellowship(JRF)received from University Grants Commission(UGC)for the doctoral research(230510492097)。
摘要Urban blue-green infrastructure(BGI)plays a significant role in regulating stormwater management and mitigating urban flooding.However,the effectiveness of urban BGI in mitigating surface runoff remains insufficiently explored,particularly in densely populated,flood-prone cities.This study presents an integrated geospatial framework to evaluate the runoff retention capacity of urban BGI and their associated flood mitigation services in Kolkata City,India.The Integrated Valuation of Ecosystem Services and Trade-Offs(InVEST)-Urban Flood Risk Mitigation(UFRM)model was applied to estimate the potential runoff generation and retention under two rainfall scenarios in Kolkata City.The model incorporated land use and land cover types,hydrological soil groups,and rainfall inputs to simulate spatial runoff patterns and runoff retention potential across different urban micro-watersheds.Flood mitigation services provided by BGI were quantified in terms of runoff retention capacity and flood volume generation.The results show that urban BGI provides substantial runoff retention capacity,with tree-covered lands and herbaceous wetlands retaining 45.0o%-60.0o%more runoff than impervious surfaces.Spatial analysis indicates that regions with permeable surfaces and dense vegetation cover enhance infiltration and water absorption,thereby demonstrating the hydrological effectiveness of BGI.The InVEST-UFRM results were validated with Synthetic Aperture Radar-derived flood data and machine learning-based models,including Random Forest(RF)model and eXtreme Gradient Boosting(XGBoost)model,with the area under curve scores(XGBoost model:0.73;RF model:0.70)confirming the model’s ability to predict flood risk.This integrated framework provides a practical tool for assessing the flood mitigation potential of BGI and offers practical insights for urban planners and policy-makers seeking to improve urban flood management and support more resilient urban landscapes.
基金Supported by the Designated Scholarship Donations from Otsuka Pharmaceutical Co.,Ltd.to the Authors’Institution(2018-2019).
摘要BACKGROUND Early postoperative edema and ascites after liver resection are common;however,the endocrine drivers of water retention are not fully defined.Arginine vasopressin(AVP)promotes antidiuresis via V2-mediated aquaporin trafficking,whereas the renin-angiotensin-aldosterone system primarily modulates sodium handling.Differences in postoperative trajectories and their relationship to early fluid retention have not been clarified in patients undergoing liver resection.AIM To examine postoperative changes in plasma AVP and plasma aldosterone concentration(PAC)after liver resection,and association with fluid retention.METHODS We conducted a prospective cohort study of adults undergoing elective liver resection at a tertiary center.Blood samples were collected preoperatively,immediately post-resection,and on postoperative days(POD)1,2,3,and 5.The primary objective was characterizing postoperative dynamics of AVP and PAC.Secondary objectives evaluated their temporal alignment with early fluid retention(body weight,urine output during POD 1-3)and compared hormonal profiles between major and minor resections.Analyses used trajectory and timebased comparisons by resection extent.RESULTS AVP increased sharply immediately after resection and remained above the preoperative baseline through POD 3,showing the most pronounced and sustained elevation after major liver resection.In contrast,PAC showed a transient postoperative increase that returned to near-baseline levels by POD 2.The period of elevated AVP closely matched the time frame during which early postoperative fluid retention was most evident,as indicated by greater short-term weight gain and reduced urine output.These patterns were consistent across sensitivity analyses and showed similar directional trends in subgroup comparisons based on resection extent.CONCLUSION AVP remains elevated longer than aldosterone and coincides with early fluid retention,particularly after major resection.Vasopressin-driven antidiuresis may be important in postoperative water retention.
基金financial support from the National Key R&D Program of China(No.2022YFC2402900 and 2022YFC2402901)the National Natural Science Foundation of China(No.82373394)+1 种基金the Sichuan Science and Technology Program(No.2025NSFTD0001)the Multidisciplinary Research Program of West China Hospital of Stomatology,Sichuan University(No.RD-03–202109)。
摘要Oral leukoplakia(OLK)is a common and representative malignant disease of oral mucosa,and possess a higher risk of cancer.Compared with traditional surgical treatment,photodynamic therapy(PDT)has great potential in OLK treatment,due to its advantages of minimally invasiveness and low toxic side effects.However,traditional photosensitizer administration suffers from short retention time due to the fluid environment of saliva and extensive tongue movement,leading to poor drug(photosensitizer)utilization and limited therapeutic outcome.To address such issue,here a photosensitive guanosine(G)-based hydrogel system(G@GQD)was constructed,in which graphene quantum dots(GQDs)featuring high photosensitization activity was loaded through three dimensional(3D)fiber network physical encapsulation.The favorable adhesion of the G@GQD hydrogel on the tongue,together with sustained GQDs release,significantly enhanced the retention of GQDs within the oral cavity.As a result,G@GQD hydrogel could continuously generate high levels of reactive oxygen species(ROS)under irradiation,demonstrating a sustained therapeutic efficiency in vitro.Compared with free GQDs,G@GQD exhibited significantly improved PDT efficiency in treating 4-nitroquinoline 1-oxide(4-NQO)-induced OLK animals.This study presented a promising strategy in overcoming the drug retention barrier that caused by saliva and tongue movement,which has far-reaching significance for the future PDT therapies.
基金the National Natural Science Foundation of China(Grant No.42272312)Ningbo Youth Science and Technology Innovation Talent Project(Grant No.2024QL057)the Zhejiang Provincial Xinmiao Talents Program(Grant No.2024R405B093).
摘要The soil-water retention curve(SWRC)plays a pivotal role in understanding water movement across numerous geological engineering applications.Despite significant advancements in theoretical modeling approaches,accurate prediction of SWRCs remains challenging due to the inherently sparse and incomplete nature of site-specific data.This study compiled a comprehensive dataset of SWRCs spanning a wide suction range from various published literature sources.Based on this dataset,multiple machine learning(ML)algorithms were employed to predict SWRCs.The performance of each algorithm was evaluated and ranked using four statistical indicators that quantify simulation accuracy.Feature importance analysis was subsequently conducted to reduce dimensionality by eliminating weakly correlated variables,thereby enhancing both model adaptability and computational efficiency.Following dimensionality reduction,a base learner pool was constructed and integrated through stacked generalization to create a multi-algorithm ensemble model.The proposed stacked model demonstrated robust performance in simulating SWRCs across diverse soil types,using only basic physical properties as inputs,achieving accuracy comparable to or marginally superior to the LightGBM model.The principal advantage of the stacked approach lies in its substantially improved accuracy within high suction ranges,effectively overcoming the limitations observed in LightGBM and enhancing the estimation under these conditions.This study provides valuable insights for researchers evaluating SWRCs through ML algorithms and demonstrates the potential of ensemble techniques in geotechnical prediction tasks.
基金supported by the Fundamental Research Funds for the Central Universities(N2001020)the National Natural Science Foundation of China(41201359).
摘要Sand dust belts span approximately one-fifth of the global land surface.In these regions,dust tends to settle on vegetation surfaces,altering the observed reflectance and affecting remote sensing detections.To enhance the accuracy of maize growth monitoring in dust-affected regions,this study aims to quantify the effect of sand dust retention on maize during the tasseling stage in the Kashgar Prefecture,Xinjiang Uygur Autonomous Region,China,by analyzing changes in canopy reflectance and vegetation indices.First,field sampling was conducted to measure the key canopy structure parameters and dust retention levels of maize,and laboratory spectral measurements were performed on leaf spectral properties under gradient dust retention.The measured data were then used to drive the LargE-Scale remote sensing data and image Simulation framework(LESS)model for simulating realistic maize canopy spectra across different dust levels,with validation against Sentinel-2 imagery.Second,on the basis of the simulated and satellite-derived spectra,the dust resistance of 36 common vegetation indices was systematically evaluated,and new robust dust-resistant indices were developed.The results showed that compared with dust-free maize,the canopy reflectance of dust-retained maize followed an increase–decrease–increase pattern,with critical turning points at 735 and 1325 nm.The maximum reflectance difference of–0.11755(change rate:29.002%)occurred within the 735–1325 nm range at 24 g/m2dust retention,and the minimum reflectance difference of 0.04285(change rate:148.950%)was observed in the 350–735 nm range under the same dust retention level.Among the 36 vegetation indices,only the global environment monitoring index(GEMI)and the ratio of transformed chlorophyll absorption in reflectance index to optimized soil-adjusted vegetation index(TCARI/OSAVI)exhibited dust resistance,with GEMI being effective below 6 g/m2and TCARI/OSAVI remaining stable across all levels(average ratio:0.970).The newly developed indices in this study,(RE3–RE2)/(NIR–RE2),(RE3–RE2)/(RE4–RE2),and(NIR–RE2)/(RE4–RE2),retained values within the predefined dust-resistant range over the full dust retention levels of 0–24 g/m2,thus showing a more stable dust resistance compared with the commonly used 36 vegetation indices.Specially,(RE3–RE2)/(RE4–RE2)performed the most robustly in Sentinel-2 imagery,that is,58.020%of pixels were within the dust-resistant range,and an average ratio of 0.937 was obtained for the original-spectra index.This study provides a scientific basis for crop monitoring and management in dust-affected regions.
基金supported by Temasek Life Sciences Laboratory core funding(3160)(to CTO).
摘要Higher prevalence of sporadic Alzheimer’s disease in women:Alzheimer’s disease(AD)is a progressive neurodegenerative disorder caused by the accumulation of amyloid-β(Aβ)plaques and Tau neurofibrillary tangles in the affected brain regions.The clearance of these pathological protein aggregates by microglia can trigger excessive neuroinflammation,which contributes to brain atrophy.AD exhibits clinical heterogeneity and is characterized by highly complex,multifactorial etiology(Lopez-Lee et al.,2024).
摘要The deployment of specialized language models in resource-constrained edge environments(≤1 B parameters,≤2 GB memory,≤100 ms latency)faces a critical challenge:Supervised Fine-Tuning(SFT)achieves domain expertise but suffers from irreversible catastrophic forgetting,while traditional Low-Rank Adaptation(LoRA)with conservative ranks(r≤64)often underperforms due to insufficient adaptation capacity.This work introduces H-LoRA(High-Rank LoRA)for edge-deployable models and establishes a fundamental distinction between destructive forgetting and controllable knowledge retention.Through comprehensive experiments on compact models(0.12 B Minimind and Qwen-0.5 B)across three domains(Human Resources,Medical,Mathematics)using 29,647 samples,we demonstrate that while both SFT and H-LoRA exhibit general capability degradation,they differ fundamentally:SFT completely destroys the original knowledge structure(1%topic retention),while H-LoRA maintains knowledge integrity with 90%topic retention—an 89 percentage point improvement—enabling post-deployment capability recovery.H-LoRA employs simplified scaling and strategic high-rank adaptation at approximately two-thirds of the model’s hidden dimension(r=512 for d=768),achieving SFT-level domain performance(99.81%precision)with 5×greater parameter efficiency(20.35%trainable parameters)and robust cross-domain generalization(93.5±6.8%average precision).In addition,H-LoRA reduces over-the-air(OTA)update size from 1.4 GB to 96 MB(≈93%),enabling practical and frequent deployment of specialized models in bandwidth-limited edge environments.Beyond demonstrating effectiveness,this work establishes the first comprehensive framework for characterizing specialization-retention trade-offs in parameter-efficient fine-tuning,providing practical guidance for method selection in real-world deployments.
基金supported by the National Natural Science Foundation of China(Grant No.52379097)the National Natural Science Foundation of China(No.52509138)+2 种基金the Water Conservancy Science and Technology Project of Jiangxi Province(Grant No.202426ZDKT27)Chongqing Natural Science Foundation Doctoral Program(CSTB2025NSCQ-BSX0020)the Research and Innovation Program for Graduate Students of Chongqing Municipality(Grant No.CYB23251).
摘要Quantifying spatial heterogeneity in soil water retention properties(SWRP)is crucial for enhancing the accuracy of hydrogeological simulations.However,studies on the spatial heterogeneity of SWRP in the Chinese Loess Plateau(CLP)remain scarce,especially at the vertical scale.We conducted laboratory tests on undisturbed loess cores collected from boreholes in CLP to analyze soil physical parameters(SPPs)and SWRP.Measured soil water characteristic curves(SWCCs)were fitted to the Brooks-Corey(BC),Fredlund-Xing(FX),and van Genuchten(vG)models.It was revealed that the FX and vG models outperformed the BC model.The geostatistical analysis identified the Gaussian model as optimal for describing the semivariograms of both SPPs and SWCC fitting parameters(FPs).Strikingly,over 90%of these parameters exhibited strong vertical spatial dependence,with an average autocorrelation length of 213.878 cm for SPPs and 320.678 cm for FPs.Moreover,SWRP was found to be significantly influenced by both SPPs and the vertical position relative to the loess ridge slope surface.Parameters near the ridge slope surface showed significantly degraded spatial dependence.These findings provide valuable insights for parameterizing the spatial heterogeneity of soil water retention properties,which are beneficial for hydrogeological modelling in shallow CLP loess strata.
基金National Key Research and Development Program of China(2022YFA1506100,X.S.)National Natural Science Foundation of China(22471201,22531010,X.S.,22503064,X.H.)for financial support.
摘要Hydrosilanes,important reagents in synthesis,typically undergo Si−H bond reactions,with selective functionalization of adjacent C−H bonds in the presence of Si−H remaining a major challenge.In this work,we present a dual‑metal photocatalytic strategy that achieves a long‑standing selectivity goal:the direct radical C−H functionalization of hydrosilanes while completely preserving the reactive Si−H bond.Unlike classical transformations where hydrosilanes act solely as reductants,our method leverages their inherentβ‑silicon effect to activate adjacent C(sp3)−H bonds.By employing a cooperative system of an Fe(III)chlorideetrabutylammonium decatungstate photocatalyst and a Cu(I)cocatalyst under light,we facilitate a chemoselective hydrogen atom transfer(HAT)and radical cross‑coupling withα‑imino esters.The reaction demonstrates broad scope,accommodating a wide range ofα‑imino esters bearing diverse electronic and steric properties,as well as various alkyl‑,aryl‑,and heterocycle‑substituted silanes.Remarkably,the process exhibits excellent selectivity for theβ‑C−H bond even in substrates containing multiple Si−H bonds,with no detectable hydrosilylation byproducts.The retained Si−H functionality serves as a versatile handle for further derivatization,as demonstrated through one‑pot etherification and catalytic hydrosilylation of alkenes and alkynes.Mechanistic studies,including light‑switching experiments,radical trapping and the isolation of self‑coupling side product from theα‑imino ester substrate,support a pathway involving ligand‑to‑metal charge transfer(LMCT)from photoexcited Fe(III)to generate chlorine radicals,subsequent hydrogen abstraction to formβ‑silyl carbon radicals,and their ultimate cross‑coupling with imine‑derivedα‑amino radicals.This work establishes a platform for the modular editing of hydrosilane frameworks,introducing a valuable disconnection for synthesizing functionally dense organosilicon molecules.
摘要This review summarizes the definition and classification,etiology and pathogenesis of postpartum urinary retention,as well as the application of Traditional Chinese Medicine(TCM)nursing techniques in its prevention and treatment.It also identifies the limitations and prospects of TCM nursing techniques in managing postpartum urinary retention,aiming to provide a reference for the clinical application and future research of TCM nursing techniques regarding this condition.
基金supported by the Sichuan Youth Science and Technology Innovation Research Team Project(No.2021JDTDO017)the open Fund(PLN2022-11)of State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation(Southwest Petroleum University)+1 种基金Southwest Petroleum University Graduate Innovation Fund(No.2022KYCX021)Jian Tian would like to acknowledge the funding from the National Natural Science Foundation of China(52404023).
摘要To elucidate the adsorption characteristics and retention mechanisms of fracturing fluids in diverse clay minerals,we conducted on-line nuclear magnetic resonance(NMR)and atomic force microscopy(AFM)experiments.The depth and extent of solid phase damage are determined by the ratio between the size of fine fractions in fracturing fluid residue and the pore-throat size in experiments.Poor physical properties(K0.5 mD)combined with a scattered distribution of retained fracturing fluid is associated with high gas phase recovery permeability,whereas a continuous sheet-like distribution results in low recovery permeability.The expansive surface area and presence of filamentous illite minerals facilitate the multiple winding and adsorption of fracturing fluids,demonstrating strong hydrogen-bonding,multi-layering and multiple adsorption properties.The geological characteristics of the main gas formations exhibit significant variation,and the severity of damage caused by fracturing fluids occurs in diverse sequences.To address this issue,a differentiated strategy for optimizing frac-turing fluids has been proposed.
基金supported by the National Natural Science Foundation of China(No.42107052)Beijing Natural Science Foundation(No.JQ21031).
摘要As a widely used fertilizer,urea significantly promotes the leaching of dissolved organic nitrogen(DON)in soils and aggravates nitrogen contamination in groundwater.Clayminerals are considered the most important factor in retaining DON.However,the effect of urea on the retention of DON with different molecular weights by clay minerals is unknown.In this study,the retention of both low-molecular weight DON(LMWD)and high-molecular weight DON(HMWD)by clay minerals in the presence of urea was investigated.For this purpose,batch adsorption and soil column leaching experiments,characterization analysis(Fourier transform infrared spectroscopy X-ray diffraction,and X-ray photoelectron spectroscopy),and molecular dynamics simulations were carried out.Urea had a positive effect on the adsorption of LMWD,whereas a competitive effect existed for the adsorption of HMWD.The dominant interactions among DON,urea,and clay minerals included H-bonding,ligand exchange,and cation exchange.The urea was preferentially adsorbed on clay minerals and formed a complex,which provided more adsorption sites to LMWD and only a few to HMWD.The presence of urea increased the retention of LMWD and decreased the retention of HMWD in clay minerals.The retention capacity of LMWD increased by 6.9%–12.8%,while that of HMWD decreased by 6.7%–53.1%.These findings suggest that LMWD tended to be trapped in soils,while HMWD was prone to be leached into groundwater,which can be used to evaluate the leaching of DON from soil to groundwater.
基金Supported by Zhejiang Province Medical and Health Technology Planning Project,No.2019332856.
摘要Gastric retention is a common complication in individuals receiving enteral nutrition(EN)via a nasogastric tube,increasing the risk of aspiration pneumonia and causing unnecessary interruptions in nutritional support.Given its clinical significance,establishing effective,evidence-based,and standardized manage-ment strategies is essential for bettering patient outcomes and mitigating compli-cations.This review systematically synthesized the diagnostic criteria,assessment methods,influencing factors,management procedures,and intervention strategies for gastric retention in EN patients.Although no universal consensus exists re-garding gastric residual volume(GRV)thresholds,evidence indicates that EN can continue at high GRV levels in the absence of gastrointestinal symptoms.Bedside ultrasound emerged as a non-invasive,and precise method GRV assessment,offering potential to standardize clinical practice.Key risk factors for gastric retention include neurological disorders and EN infusion rates exceeding 100 mL/h.Effective management strategies encompass non-pharmacological inter-ventions,pharmacological agents,and traditional Chinese medicine(TCM)the-rapies.This review underscored the need for integrated,multi-modal manage-ment strategies and recommended the adoption of bedside ultrasound and stan-dardized protocols to optimize EN delivery and improve patient outcomes.Large-scale,multicenter clinical trials should be a priority for future investigation to verify the effectiveness of TCM therapies and develop personalized intervention plans for high-risk patients.
基金funded by Directorate General of Higher Education,Reserach,and Technology,Ministry of Education,Culture,Reserach,and Technology of Indonesia(Grant number:1325/UN3.LPPM/PT.01.03/2023).
摘要Objectives:This study aimed to explore the voices of Indonesian migrant nurses on their retention in Japanese healthcare facilities.Methods:A descriptive qualitative study was conducted between June and September 2023.The snowball sampling method was utilized to recruit 22 Indonesian nurses working in healthcare facilities in seven prefectures of Japan.Semi-structured interviews were conducted based on their shared experiences.All interview data were audio-recorded,transcribed verbatim,and analyzed using thematic analysis.Results:Six prominent themes and 15 subthemes emerged:1)organizational factors(caring leader,involvement in decision making,career development,and participation in training);2)social support systems(group support,colleagues support and friend support);3)individual drive(lifelong learning and persistent);4)national policies(government support in public service and flexibility in finding a comfortable placement);5)family factors(positive support of child education and development and maintaining relationship with spouse);and 6)economic factors(staying due to high salary and increasing income streams).Conclusions:Retention of Indonesian migrant nurses in Japan is a multifaceted challenge that hinges on various interconnected factors.This study has gone some way toward enhancing our understanding of international nurse retention in the receiving countries.Corresponding supports at the individual,family,organizational,economic,social,and national policy levels should be considered to keep them in their destination countries.
基金funded by National Natural Science Foundation of China(51901160)。
摘要For the purpose of satisfying high demands for taste,color,flavor,and storage of meat products,water retention agents(WRAs)play an important role.Phosphate has been widely used as an attractive functional material for water retention in current practical applications.However,excessive phosphate addition and longterm consumption may be harmful impacts on health and the environment.Therefore,it is vital to develop safe and efficient phosphate-free WRAs for further improving water-holding capacity(WHC)efficacy and edible safety,especially in meat products.In particular,sugar water retention agents(SWRAs)are increasingly popular because of their perfect safety,excellent WHC,and superior biological properties.This review discusses the inducements and mechanisms underlying water loss in meat products.In addition,we focused on the research progresses and related mechanisms of SWRAs in the WHC of meat products and its unique biological functions,as well as the extraction technology.Finally,the future application and development of SWRA were prospected.