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Diterpenoids from Isodon sculponeatus 认领 引用 被引量：4
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作者 姜北 梅双喜 +3 位作者 赵爱华 孙汉董 吕扬 郑启泰 《Chinese Journal of Chemistry》 SCIE CAS 2002年第9期887-890,共4页
b Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China c Pharmaceutical Department of Dali College, Dali, Yunnan 671000, China Further investigation on the leaves of Isodon sculponea... b Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China c Pharmaceutical Department of Dali College, Dali, Yunnan 671000, China Further investigation on the leaves of Isodon sculponeatus afforded two new ent kaurane diterpenoids, sculponeatins J and K . Their structures were elucidated on the basis of their spectral properties, as well as X ray crystallographic analysis. The cytotoxicities of these two new compounds against human tumor cells K562 and T24 were also tested, and sculponeatin J showed significant inhibitory effects with IC 50 values less than 1.0 μg/mL. 展开更多
关键词 Isodon sculponeatus Labiatae ent kauranoid sculponeatins J and K cytotoxicity
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