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Premature termination in streptovaricin biosynthesis reveals unnatural short-chain analogues 认领 引用
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作者 Zi-Ru Wang Pei-Yi Liu +4 位作者 Chao Zhang Zhang-Yuan Yan Hui-Ming Ge Ren-Xiang Tan Zi-Fei Xu 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第6期484-488,共5页
This study reports the discovery of three shortened streptovaricin analogues,prestreptovaricins A–C(2–4),from Streptomyces spectabilis NA07477.Through comprehensive NMR and HRMS analysis,we elucidated their structur... This study reports the discovery of three shortened streptovaricin analogues,prestreptovaricins A–C(2–4),from Streptomyces spectabilis NA07477.Through comprehensive NMR and HRMS analysis,we elucidated their structures as a linear C13-polyketide(2),a 15-membered(3),and a 17-membered macrolactam(4),representing the first divergence from the character-istic C23 ansa chain in this antibiotic family.Gene inactivation experiments demonstrated that these truncated metabolites result from premature chain release at modules 5–7 of the polyketide synthase,rather than module skipping.Notably,the cyclized products 3 and 4 persisted upon knockout of the dedicated amide synthase stvF,implying catalysis by promiscuous cyclases.Our findings uncover premature termination as a previously unrecognized pathway for structural diversification in ansamycin biosynthesis. 展开更多
关键词 Ansamycins Streptovaricin Prestreptovaricins A-C Biosynthesis Premature termination
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Radiation hardness of 1.2 kV SiC power devices with advanced edge termination structures under proton irradiation 认领 引用
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作者 Sangyeob Kim Jeongtae Kim +3 位作者 Dong-Seok Kim Hyuncheol Bae Min-Woo Ha Ogyun Seok 《Journal of Semiconductors》 EI CAS CSCD 2026年第1期83-89,共7页
This work presents a systematic analysis of proton-induced total ionizing dose(TID)effects in 1.2 k V silicon carbide(SiC)power devices with various edge termination structures.Three edge terminations including ring-a... This work presents a systematic analysis of proton-induced total ionizing dose(TID)effects in 1.2 k V silicon carbide(SiC)power devices with various edge termination structures.Three edge terminations including ring-assisted junction termination extension(RA-JTE),multiple floating zone JTE(MFZ-JTE),and field limiting rings(FLR)were fabricated and irradiated with45 Me V protons at fluences ranging from 1×1012 to 1×1014 cm-2.Experimental results,supported by TCAD simulations,show that the RA-JTE structure maintained stable breakdown performance with less than 1%variation due to its effective electric field redistribution by multiple P+rings.In contrast,MFZ-JTE and FLR exhibit breakdown voltage shifts of 6.1%and 15.2%,respectively,under the highest fluence.These results demonstrate the superior radiation tolerance of the RA-JTE structure under TID conditions and provide practical design guidance for radiation-hardened Si C power devices in space and other highradiation environments. 展开更多
关键词 SiC proton irradiation edge termination radiation hardness TID effects
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Design of improved error-rate sliding window decoder for SC-LDPC codes: reliable termination and channel value reuse 认领 引用
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作者 JIA Xishan LI Jining +3 位作者 YAO Yuan WANG Yifan LIU Bo XU Degang 《Optoelectronics Letters》 EI 2025年第4期212-217,共6页
In this paper,an improved error-rate sliding window decoder is proposed for spatially coupled low-density parity-check(SC-LDPC)codes.For the conventional sliding window decoder,the message retention mechanism causes u... In this paper,an improved error-rate sliding window decoder is proposed for spatially coupled low-density parity-check(SC-LDPC)codes.For the conventional sliding window decoder,the message retention mechanism causes unreliable messages along the edges of belief propagation(BP)decoding in the current window to be kept for subsequent window decoding.To improve the reliability of the retained messages during the window transition,a reliable termination method is embedded,where the retained messages undergo more reliable parity checks.Additionally,decoding failure is unavoidable and even causes error propagation when the number of errors exceeds the error-correcting capability of the window.To mitigate this problem,a channel value reuse mechanism is designed,where the received channel values are utilized to reinitialize the window.Furthermore,considering the complexity and performance of decoding,a feasible sliding optimized window decoding(SOWD)scheme is introduced.Finally,simulation results confirm the superior performance of the proposed SOWD scheme in both the waterfall and error floor regions.This work has great potential in the applications of wireless optical communication and fiber optic communication. 展开更多
关键词 reliable termination message retention mechanism reliable termination method sliding window decoderthe error rate sliding window decoder belief propagation bp decoding retained messages
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The maize mTERF18 regulates transcriptional termination of the mitochondrial nad6 gene and is essential for kernel development 认领 引用
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作者 Zhengwei Guan Yong Wang Jun Yang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2025年第3期422-431,共10页
Mitochondria are semi-autonomous organelles present in eukaryotic cells,containing their own genome and transcriptional machinery.However,their functions are intricately linked to proteins encoded by the nuclear genom... Mitochondria are semi-autonomous organelles present in eukaryotic cells,containing their own genome and transcriptional machinery.However,their functions are intricately linked to proteins encoded by the nuclear genome.Mitochondrial transcription termination factors(mTERFs)are nucleic acid-binding proteins involved in RNA splicing and transcription termination within plant mitochondria and chloroplasts.Despite their recognized importance,the specific roles of mTERF proteins in maize remain largely unexplored.Here,we clone and functionally characterize the maize mTERF18 gene.Our findings reveal that mTERF18 mutations lead to severely undifferentiated embryos,resulting in abortive phenotypes.Early kernel exhibits abnormal basal endosperm transfer layer and a significant reduction in both starch and protein accumulation in mterf18.We identify the mTERF18 gene through mapping-based cloning and validate this gene through allelic tests.mTERF18 is widely expressed across various maize tissues and encodes a highly conserved mitochondrial protein.Transcriptome data reveal that mTERF18 mutations disrupt transcriptional termination of the nad6 gene,leading to undetectable levels of Nad6 protein and reduced complex I assembly and activity.Furthermore,transmission electron microscopy observation of mterf18 endosperm uncover severe mitochondrial defects.Collectively,these findings highlight the critical role of mTERF18 in mitochondrial gene transcription termination and its pivotal impact on maize kernel development. 展开更多
关键词 mTERF18 Mitochondria Zea mays Transcriptional termination Kernel development Nad6
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Prolonged seasons of compound heat-humidity extremes amplify vulnerable population exposure in eastern China 认领 引用 被引量：1
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作者 Miaoni Gao Xinyue Sun +3 位作者 Buda Su Lu Tang Xingyu Cheng Tong Jiang 《Atmospheric and Oceanic Science Letters》 CAS CSCD 2026年第3期58-63,共6页
Compound heat–humidity extremes(CTHEs)pose escalating threats to human health,particularly for vulnerable populations(children and elderly)with limited physiological adaptability.This study reveals the expansion of C... Compound heat–humidity extremes(CTHEs)pose escalating threats to human health,particularly for vulnerable populations(children and elderly)with limited physiological adaptability.This study reveals the expansion of CTHE-active seasons across eastern China from 1961 to 2022.Southern China(SC)and the Yangtze–Huaihe region(YH)exhibit earlier onsets and delayed terminations,prolonging hazardous CTHE seasons by one month post-2015 in SC.The prolonged CTHE-active seasons,coupled with population growth,have driven sharp increases in exposure across eastern China,with annual CTHE and hazardous CTHE exposure increasing by 106 million and 78 million person-days since the 2000s.Vulnerable groups constitute 39%of total exposure,with 11%(CTHEs)and 34%(hazardous CTHEs)attributable to season prolongation.Mechanistically,an intensified and westward-extended western North Pacific subtropical high enhances diabatic heating and moisture advection,driving prolonged CTHE-active seasons in SC and YH.These findings quantify climate–demographic synergies in heat–health risks,providing a scientific basis for climate-resilient health strategies targeting age-sensitive populations in eastern China’s warming and humidifying hotspots. 展开更多
关键词 Compound heat-humidity extremes Onset and termination Western north Pacific subtropical high Vulnerable population exposure
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Synergistic effect of oxygen vacancies and positively charged Ag clusters on Ag/CeO2 for efficient carboxylation of terminal alkynes with CO2 认领 引用
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作者 Jing Li Zhanwei Ma +4 位作者 Tingting Wang Chengli Song Qinsheng Zhang Xinyuan Mu Bin Hu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第2期569-578,I0013,共10页
The carboxylation of alkynes with CO2 has attracted considerable interest due to the valorization of C1resources and atomic economy.Much effort focused on active metals(e.g.,Au,Ag,Cu),while the mechanistic role of ... The carboxylation of alkynes with CO2 has attracted considerable interest due to the valorization of C1resources and atomic economy.Much effort focused on active metals(e.g.,Au,Ag,Cu),while the mechanistic role of active supports,particularly the oxygen vacancy(Ov),in modulating C-H bond carboxylation remains unknown.Herein,ultra-small silver clusters and morphologically engineered CeO2 support(nanorods,nanocubes,and nano particles)were employed to construct Ag cluster/Ov synergistic catalyst,which exhibits variations in Oy concentration by an in situ auto-reduction method.The 0.197%Ag/CeO2-NR catalyst exhibited a high reaction rate for the phenylacetylene carboxylation reaction and the maximal silver utilization efficiency.The characterization and DFT calculations demonstrated that vacancies enhanced CO2 adsorption via polarization-induced molecular bending and C-O bond elongation.Positively charged Ag clusters induced by metal-support interactions serve as deprotonation activation centers for alkynes.This synergistic interplay between dual active sites efficiently facilitates the C(sp)-H carboxylation with CO2.These findings offer critical insights for the rational selection of active supports in designing efficient C-H carboxylation catalysts. 展开更多
关键词 Carboxylation CO2 Terminal alkyne Oxygen vacancy Metal-support interaction
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Analysis and Modelling of Salt-related Deformation in the Western Sichuan Foreland Basin,China 认领 引用
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作者 QIU Dengfeng HU Zongquan +2 位作者 John J.WALSH GUO Jinrui ZHANG Zhongming 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2026年第1期265-285,共21页
The Western Sichuan Foreland Basin(WSFB)in South China,a prolific hydrocarbon province,exhibits complex structural deformation influenced by Triassic salt tectonics.This paper integrates seismic data and well data to ... The Western Sichuan Foreland Basin(WSFB)in South China,a prolific hydrocarbon province,exhibits complex structural deformation influenced by Triassic salt tectonics.This paper integrates seismic data and well data to elucidate the role of Middle-Lower Triassic evaporite layers in shaping basin structures,focusing on Xinchang Tectonic Zone(XTZ).Salt layers facilitated decoupled deformation between supra-and sub-salt sequences,forming salt pillows and fault-related folds.Three distinct structural trends were identified in XTZ.Key findings reveal that salt thickness variations correlate with deformation styles:thicker salt promoted detachment folding,while thinner salt led to hard-linked fault systems.Sub-salt E-NE trending reverse faults formed horsetail terminations associated with the Pengzhou faults(PzF),deviating from the primary Longmenshan thrust belt(LmsTB)orientation.Structural evolution occurred in three stages:(1)Indosinian salt deposition and foreland basin initiation;(2)Yanshanian eastward propagation of thrust systems with salt-driven detachment folding;(3)Himalayan reactivation overprinting earlier structures with sub-NS trending folds.This work establishes a direct link between salt layers and structural traps,demonstrating how salt acted as a critical detachment layer during multi-stage compression.Results provide insights into the gas exploration of the Late Triassic Xujiahe Formation,emphasizing the importance of salt-influenced deformation in foreland basin systems. 展开更多
关键词 salt structure fault horsetail terminations foreland basin western Sichuan
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Stiffness evaluation and experimental test of a novel redundantly actuated parallel machining robot 认领 引用
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作者 Hanliang Fang Jian Wang +2 位作者 Shuyi Ge Fufu Yang Jun Zhang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2026年第1期413-422,共10页
Parallel machining robot is a new type of robotized equipment for high-efficiency machining structural com-ponents with complex geometries.Terminal rigidity is of great importance index for such type of equipment,whic... Parallel machining robot is a new type of robotized equipment for high-efficiency machining structural com-ponents with complex geometries.Terminal rigidity is of great importance index for such type of equipment,which affects their load capacity and working accuracy.Before a parallel machining robot can be used for heavy-load and high-efficiency machining,its terminal rigidity should be evaluated systematically.The present study is to quantitatively reveal the stiffness properties of a previously invented Z4 redundantly actuated parallel ma-chining robot(RAPMR).For this purpose,two critical issues,i.e.,stiffness modelling and index construction,are clarified to carry out stiffness evaluation of the Z4 RAPMR.Firstly,drawing on the screw theory,a semi-analytic stiffness model of the proposed RAPMR is established at a component level.Secondly,a set of virtual work-based stiffness indices is constructed to evaluate the terminal rigidity of parallel robots.Those indices have a consistent physical unit in describing linear and angular terminal rigidity.With these indices,the local and the global stiffness performance of the Z4 RAPMR are predicted.Thirdly,a laboratory prototype of the proposed RAPMR is fabricated.And the experimental test is performed to verify the correctness of the established stiffness model.The present work is expected to provide fundamental information for further light-weight design and rigidity enhancement. 展开更多
关键词 Parallel machining robot Redundantly actuated Terminal rigidity Stiffness model Experimental test
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Diquafosol ophthalmic solution on ocular surface parameters in visual display terminal-associated dry eye disease 认领 引用
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作者 Ting-Ting Yang Hong-Yu Duan +7 位作者 Yi-Fan Zhou Bai-Kai Ma Lu Zhao Qian-Qian Lan Jia-Wei Chen Xiao-Yu Wang Kyung Chul Yoon Hong Qi 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2026年第4期673-680,共8页
AIM:To evaluate 3%diquafosol ophthalmic solution on ocular surface parameters and the alterations of lipid and muco-aqueous layer in tear film of patients with visual display terminal(VDT)-associated dry eye disease(D... AIM:To evaluate 3%diquafosol ophthalmic solution on ocular surface parameters and the alterations of lipid and muco-aqueous layer in tear film of patients with visual display terminal(VDT)-associated dry eye disease(DED).METHODS:This study included patients with VDTassociated DED.It was a prospective single-arm interventional clinical trial.Patients were provided with 3%diquafosol ophthalmic solution for 3mo and were followed up in 1,2 and 3mo after treatment.Tear breakup time(TBUT),ocular surface staining score,and ocular surface disease index(OSDI)score were ocular surface characteristics.Lipid layer thickness(LLT),tear meniscus height(TMH),and mucin mRNA expression levels(MUC1,MUC4,MUC5AC,MUC16,and MUC20)were used to measure changes in the tear film.The LipiView interferometer was used to measure the partial blink rate(PBR).RESULTS:Sixty-eight eyes of 68 participants(54 females;mean age 25.12±4.10y;mean spherical equivalent-4.35±2.69 D)were enrolled.Compared with the pre-treatment,OSDI scores and TBUT improved significantly at all follow-up time points(all P<0.01),and TMH increased significantly at 1 and 3mo(P<0.01,P<0.001,respectively).Conjunctival lissamine green staining improved only at 2mo(P<0.05),while corneal fluorescein staining showed no significant changes.Overall LLT remained unchanged,but the PBR<1 subgroup exhibited significant LLT elevation at 3mo(P<0.05),unlike the PBR=1 subgroup.Conjunctival mRNA expression of MUC1,MUC5AC,MUC16,and MUC20 was significantly upregulated at 1 and 3mo(all P<0.01),and MUC4 expression increased significantly only at 1mo(P<0.001).CONCLUSION:In patients with VDT-associated DED,3%diquafosol ophthalmic solution dramatically reduced symptoms and enhanced tear film stability by promoting ocular surface muco-aqueous secretion.Patients with better blinking habits(PBR<1)demonstrate greater LLT improvement than those with poorer habits. 展开更多
关键词 dry eye disease visual display terminal diquafosol mucin
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Microbial Diversity in Airport Terminal Environments and Potential Aerosol Transmission Risks 认领 引用
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作者 Zhuona Zhang Qin Wang +3 位作者 Xiaoyan Dong Xia Li Bo Lu Dongqun Xu 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2026年第5期512-528,共17页
Objective To characterize the distribution of bacterial and fungal pathogens in airport terminal environments,compare airborne aerosol sampling methods,identify high-abundance pathogenic species based on the WHO prior... Objective To characterize the distribution of bacterial and fungal pathogens in airport terminal environments,compare airborne aerosol sampling methods,identify high-abundance pathogenic species based on the WHO priority pathogens list,and provide a scientific basis for optimizing microbiological monitoring and control measures.Methods Sampling was conducted in the transit transfer area(A1),domestic arrivals area(A2),and domestic departures area(A3).Airborne aerosols were collected using cyclonic and filtration samplers,and surface samples were collected using sterile swabs.DNA analysis was performed using 2bRAD sequencing for microbiome profiling(2bRAD-M).Microbial community diversity and compositional differences were assessed usingα-diversity indices(Chao1,Shannon,and Simpson)andβ-diversity metrics.Results Bacteria dominated the indoor air microbiota of the airport terminal(98.4%),with Pseudomonadota(39.4%–62.9%)and Actinomycetota(18.9%–32.9%)as the predominant phyla.Microbial diversity was significantly higher in surface samples than in airborne aerosols.High-frequency contact surfaces(e.g.,handrails)were enriched with human commensal bacteria,including Cutibacterium acnes(9.71%–19.4%).Multiple WHO-prioritized pathogens were detected,including Acinetobacter baumannii(0.3%–1.4%)and Pseudomonas aeruginosa(0.01%–1.24%).The transit transfer area(A1),characterized by poorer ventilation,showed higher microbial richness.Filtration samplers captured more microorganisms per unit volume than cyclonic samplers,with significant differences in detection profiles.Conclusion Sampling methods,sample types,and environmental conditions influence microbial distribution patterns across terminals.Detection of WHO Critical and High priority pathogens indicates potential risks of aerosol and contact transmission.Enhanced ventilation and disinfection of highfrequency contact surfaces can mitigate public health risks. 展开更多
关键词 Airport terminal Microbial diversity Aerosol and surface sampling 2bRAD-M WHO priority pathogens Transmission risk
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Preparation Process and Performance Evaluation of Terminal Blend Composite-modified Asphalt 认领 引用
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作者 YUAN Yan WANG Yefei +2 位作者 CHEN Hongyu XU Song ZHENG Zhidong 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2026年第1期200-209,共10页
To explore the best preparation process for terminal blend(TB)composite-modified asphalt and to filter its formulation with excellent performance,this study evaluates the performance of TB composite modified asphalt b... To explore the best preparation process for terminal blend(TB)composite-modified asphalt and to filter its formulation with excellent performance,this study evaluates the performance of TB composite modified asphalt by physical property index,microscopic morphology,rheological testing,and infrared spectroscopy on multiple scales.The results show that the best preparation process for TB-modified asphalt is stirring at 260℃ for 4 h at 400 rpm,which significantly reduces the modification time of the asphalt.From a physical property viewpoint,the TB composite-modified asphalt sample with 5% styrene-butadiene-styrene(SBS)+1% aromatics+0.1% sulfur exhibits high-comprehensive,high-and low-temperature properties.More-over,its crosslinked mesh structure comprises black rubber particles uniformly interwoven in the middle,which further enhances the performance of the asphalt and results in an excellent performance formulation.In addition,the sample with 5%SBS content has a higher G*value and smaller δ value than that with 3%SBS content,indicating that its high-temperature resistance is improved.The effect of adding 3%SBS content on the viscoelastic ratio is,to some extent,less than that caused by 20% rubber powder. 展开更多
关键词 road engineering terminal blend rubberized asphalt preparation process modification mechanism
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Letter to the Editor:Gut microbiota–bile acid crosstalk-Prevotellaceae NK3B31 and 7-ketolithocholic acid drive metabolic benefits of distal bowel resection with preservation of terminal ileum 认领 引用
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作者 Xu Cui Long-Yao Xu +3 位作者 Bing-Qian Yin Liu Chen Zheng Liang Chao-Ming Zhou 《World Journal of Hepatology》 2026年第5期313-317,共5页
This letter commends on the study published in World Journal of Gastroenterology by Xu et al,which elucidated the mechanism by which distal bowel resection with terminal ileum preservation(DBRPI)improves hepatic gluco... This letter commends on the study published in World Journal of Gastroenterology by Xu et al,which elucidated the mechanism by which distal bowel resection with terminal ileum preservation(DBRPI)improves hepatic gluconeogenesis via the Prevotellaceae NK3B31_group/7-ketolithocholic acid(7-KLCA)/farnesoid X receptor(FXR)axis.Using multiomics and functional assays,Xu et al identified this microbial–bile acid(BA)axis as central to the metabolic benefits of DBRPI,linking microbial enrichment(e.g.,Prevotellaceae NK3B31_group)to increased 7-KLCA levels and FXR activation,thereby suppressing gluconeogenic gene expression.We highlight the novelty of this work in its focus on taxon-specific microbial and BA dynamics,which advances the understanding of postoperative glucose regulation.Additionally,we note its translational potential—targeting this axis via probiotics or 7-KLCA analogs—and raise several open questions,including causal validation of the microbial taxon,serum 7-KLCA dynamics,and glucagon-likepeptide-1/FXR interplay.Overall,this study bridges gut microbiota and BA crosstalk,offering actionable insights for the treatment of metabolic disease. 展开更多
关键词 Distal bowel resection with terminal ileum preservation Gut microbiota Bile acid metabolism Prevotellaceae NK3B31_group 7-ketolithocholic acid Glucose homeostasis
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基于直流大母线的大规模海上风电混合多端直流并网系统 认领 引用 被引量：4
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作者 涂睿 向往 +4 位作者 郑双燕 雷雅珺 韩杏宁 张文嘉 文劲宇 《电网技术》 EI CSCD 北大核心 2026年第5期1937-1946,I0052,共10页
随着海上风电并网规模的不断扩大,沿海通道资源日趋紧张,常规的点对点输电方式已难以满足风电扩建需求,并且传统的交流主干网架也难以消纳大规模新能源。提出了一种基于直流大母线的大规模海上风电直流并网系统,充分考虑了不同海上风电... 随着海上风电并网规模的不断扩大,沿海通道资源日趋紧张,常规的点对点输电方式已难以满足风电扩建需求,并且传统的交流主干网架也难以消纳大规模新能源。提出了一种基于直流大母线的大规模海上风电直流并网系统,充分考虑了不同海上风电接入方式的集中汇集方法。海上风电场与滩涂光伏场站发出的电能通过汇集海缆整流输送至陆上直流大母线,再分散送出至各陆上电网。首先介绍了系统的拓扑结构,分析了系统的6种运行模式。考虑系统短路故障应对方案的技术经济性,提出了设备配置优选方案。随后,提出了系统的协调控制策略及交直流故障穿越策略。在PSCAD/EMTDC中搭建了并网系统的仿真模型,验证了该系统在启动、功率波动与直流故障工况下的运行特性。 展开更多
关键词 海上风电 多端直流输电系统 直流大母线 控制策略 故障穿越
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面向配电网计算推演的智能终端部署优化方法 认领 引用 被引量：1
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作者 钟加勇 王雪文 +2 位作者 刘丁豪 崔秋实 冉茂菊 《电力系统保护与控制》 EI CSCD 北大核心 2026年第3期177-187,共11页
当前配电网智能终端部署存在感知终端配置覆盖水平不足与重复部署共存的问题,且“一台区一终端”尚未实现,缺乏智能配电终端配置标准,导致运维工作量增加。对此,提出了面向智能配电网计算推演的终端部署优化方法。首先,提出“最小化精... 当前配电网智能终端部署存在感知终端配置覆盖水平不足与重复部署共存的问题,且“一台区一终端”尚未实现,缺乏智能配电终端配置标准,导致运维工作量增加。对此,提出了面向智能配电网计算推演的终端部署优化方法。首先,提出“最小化精准采集+数字系统计算推演”的智能终端部署优化方法,通过优化终端部署、强化专业协同、深化数据应用的“三措并举”策略,制定面向智能配电终端部署的差异化配置策略。然后,基于上述部署优化方法提出了面向智能配电网的计算推演方法,通过建立基于智能终端的配电网计算推演流程,提升配电网智能化水平,支持分布式能源、储能和电动汽车的发展。最后,通过仿真实验证明了所提方法的有效性。 展开更多
关键词 计算推演 智能配电终端 精准数据采集 智能配电网
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一种结合ZigBee与OneNET云平台的多终端室内无线消防数据采集与预警系统 认领 引用 被引量：2
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作者 田军南 陈樟柯 +1 位作者 李伟 蒋吉慧 《机械设计与制造》 北大核心 2026年第4期264-271,共8页
针对当前火灾隐患不易发觉、消防检查数据采集难、消防检查工作量大等问题,设计了一种结合ZigBee与OneNET云平台的多终端室内无线消防数据采集与预警系统。该系统以STM32为核心主控制器,硬件部分包括ZigBee模块、GSM模块、GPS定位模块... 针对当前火灾隐患不易发觉、消防检查数据采集难、消防检查工作量大等问题,设计了一种结合ZigBee与OneNET云平台的多终端室内无线消防数据采集与预警系统。该系统以STM32为核心主控制器,硬件部分包括ZigBee模块、GSM模块、GPS定位模块、显示模块、WiFi模块、电动水阀控制模块、报警模块以及温湿度等环境数据采集传感器。软件部分利用ZigBee模块通信驱动程序、数据存储与分析模块以及OneNET云平台等实现所设计的功能。系统通过传感器采集数据,并借助卡尔曼-指数平滑滤波进行数据预处理,再传输至主控制器,利用基于阈值的火灾探测算法进行判断,并实时将监测数据上传至OneNET云平台进行数据存储、分析和预警。测试结果表明,该设计方案稳定可靠,实现了消防数据采集和预警的智能化、简便化及科学化,能够有效保障消防安全和人员的生命安全。 展开更多
关键词 ZigBee OneNET云平台 数据预处理 火灾预警 多终端
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高比例新能源大送端基地风光火储容量优化配置 认领 引用 被引量：3
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作者 张爱军 刘会强 +2 位作者 慕腾 王秀丽 文福拴 《现代电力》 CSCD 北大核心 2026年第2期356-367,I0019,I0020,共12页
在双碳能源战略目标背景下,为应对内蒙古电力系统新能源接纳能力的不断提升,提高沙漠基地环境下投资风光火储的能源利用率,提出一种考虑不同典型日和不同场景下多耦合变量的优化模型。首先,建立风光火储荷的优化模型。其次,在考虑风光... 在双碳能源战略目标背景下,为应对内蒙古电力系统新能源接纳能力的不断提升,提高沙漠基地环境下投资风光火储的能源利用率,提出一种考虑不同典型日和不同场景下多耦合变量的优化模型。首先,建立风光火储荷的优化模型。其次,在考虑风光火储投资及运行成本的基础上,根据投资容量和负荷功率的耦合特性,构建考虑内用负荷和外送通道容量需求的优化双层模型。最后,构建对应四大沙漠的4种运行场景,通过Matlab软件平台进行仿真,并用Cplex进行求解,获得风光火储的最优容量配置。算例仿真结果表明,该文所配置的风光火储可以协调电力系统运行,兼顾内用和外送负荷的需求,提高系统的能源供给平衡度。 展开更多
关键词 送端基地 风光火储 容量布局优化 外送容量 内需负荷
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Current status and prospects of guidance techniques for intercepting hypersonic glide vehicles:A review 认领 引用 被引量：2
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作者 Feng Wang Qiankun Qu +3 位作者 Hao Yang Shou Zhou Xibin Bai Shifeng Zhang 《Defence Technology（防务技术）》 SCIE EI CAS CSCD 2026年第4期241-259,共19页
Hypersonic vehicles present formidable challenges to existing air and missile defence systems due to their extreme velocity,extended-range strike capability,and exceptional maneuverability,driving the need for advance... Hypersonic vehicles present formidable challenges to existing air and missile defence systems due to their extreme velocity,extended-range strike capability,and exceptional maneuverability,driving the need for advanced guidance technologies of interceptors.To address the requirements for defensive operations against hypersonic vehicles,this review focuses on hypersonic glide vehicles(HGVs)as the primary object of study.Their flight characteristics are simulated,and critical interception challenges are analyzed.Then,key technological advancements in interceptor guidance,including midcourse guidance techniques,mid-terminal guidance handover,and terminal guidance laws,are reviewed,providing a comparative analysis of their respective strengths and limitations.Finally,the research summarizes the pivotal scientific problems confronting interceptor guidance technology and provides prospects for the research directions of related technologies.These findings provide a valuable reference for subsequent research on interceptor guidance technology and facilitate the development of next-generation aerospace defence architectures. 展开更多
关键词 Hypersonic glide vehicles interception Trajectory planning Trajectory tracking control Mid-terminal guidance handover Terminal guidance law Cooperative guidance
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重度子痫前期患者血清Endocan水平变化对心功能的影响 认领 引用 被引量：1
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作者 杨维 蔡凤娥 +2 位作者 李景姗 杨博 谭家余 《中国妇幼保健》 CAS 2026年第2期243-246,共4页
目的探讨重度子痫前期(PE)患者血清Endocan水平的变化及对心功能的影响。方法选择2021年1月—2023年6月于中山市博爱医院产科和ICU收治的重度PE患者169例(重度PE组),另选择同期收治的PE患者93例(PE组)、慢性高血压伴发PE(PSOCH)84例(PS... 目的探讨重度子痫前期(PE)患者血清Endocan水平的变化及对心功能的影响。方法选择2021年1月—2023年6月于中山市博爱医院产科和ICU收治的重度PE患者169例(重度PE组),另选择同期收治的PE患者93例(PE组)、慢性高血压伴发PE(PSOCH)84例(PSOCH组)、正常孕妇113例(正常孕妇组)为研究对象。检测4组孕妇血清Endocan的水平及采用受试者工作特征曲线分析Endocan的诊断价值,对重度PE组和正常孕妇组的心功能指标[血清氨基末端脑钠肽前体(NT-proBNP)、二尖瓣口舒张早期血流速度峰值/二尖瓣环根部运动速度峰值(E/Ea)、射血分数(EF)]进行比较,采用相关分析法分析重度PE组患者中血清Endocan水平与心功能指标的相关性。结果(1)正常孕妇组、PE组、重度PE组及PSOCH组的Endocan水平中位数值分别为1914.35 pg/ml、2031.28 pg/ml、2376.79 pg/ml、1970.05 pg/ml,与正常孕妇组相比,PE组血清Endocan水平有所增高,差异有统计学意义(P0.05)。(2)血清Endocan诊断重度PE的曲线下面积为0.852,灵敏度为82.2%,特异度为86.3%。(3)与正常孕妇组相比,重度PE组的NT-proBNP水平和E/Ea比值均明显增高,差异均有统计学意义(P<0.01),EF则降低(P<0.05)。(4)相关性分析显示,重度PE组的血清Endocan与NT-proBNP和E/Ea比值呈正相关(r=0.576,P<0.01;r=0.721,P<0.01),与EF呈负相关(r=-0.218,P<0.01)。结论血清Endocan水平在重度PE患者中明显升高,可作为重度PE的早期诊断指标,并可能与患者心功能变化有关。 展开更多
关键词 重度子痫前期 Endocan 血清氨基末端脑钠肽前体 射血分数
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生物安全三级实验室结核分枝杆菌终末消毒试验研究 认领 引用 被引量：1
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作者 王劲松 李军丽 +3 位作者 黄洋 牛群 马丽颖 陈国庆 《中国消毒学杂志》 CAS 2026年第1期18-21,共4页
目的研究生物安全三级实验室(P3实验室)结核分枝杆菌终末消毒效果,为P3实验室终末消毒方法的优化提供参考。方法采用载体定性杀菌试验方法,对某P3实验室的终末消毒效果进行观察。结果采用汽化过氧化氢消毒机,在实验室空间内过氧化氢12.8... 目的研究生物安全三级实验室(P3实验室)结核分枝杆菌终末消毒效果,为P3实验室终末消毒方法的优化提供参考。方法采用载体定性杀菌试验方法,对某P3实验室的终末消毒效果进行观察。结果采用汽化过氧化氢消毒机,在实验室空间内过氧化氢12.8 g/m3蒸汽熏蒸作用条件下,实验室内25个布点处中待检菌对照、指示菌以及操作环境中待检菌的培养结果均为无菌生长,阳性对照组培养全部有菌生长。结论采用汽化过氧化氢消毒机在本研究试验条件下,对P3实验室内环境设备和空间均达到终末消毒合格的要求。 展开更多
关键词 生物安全实验室 终末消毒 汽化过氧化氢消毒机 消毒效果
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计及多种分布式能源的多端直流配电网故障电流计算方法 认领 引用 被引量：2
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作者 贾东梨 任昭颖 +3 位作者 刘科研 叶学顺 李跃涛 徐利梅 《中国电力》 CSCD 北大核心 2026年第1期84-96,共13页
直流配电网短路故障电流将在极短时间内上升至正常运行电流的数倍,对系统保护与安全运行构成严峻挑战。直流配电网中含有多种分布式能源,其并网变流器多样、耦合关系复杂,导致故障特性分析与故障电流计算困难,不利于保护策略设计。为此... 直流配电网短路故障电流将在极短时间内上升至正常运行电流的数倍,对系统保护与安全运行构成严峻挑战。直流配电网中含有多种分布式能源,其并网变流器多样、耦合关系复杂,导致故障特性分析与故障电流计算困难,不利于保护策略设计。为此,提出含多种分布式能源的直流配电网故障电流计算模型。首先,建立电压源型变流器(voltage source converter,VSC)的故障等效回路,并分析分布式光伏Boost变换器、分布式风电机侧变流器(modular multilevel converter,MSC)、储能双有源桥变流器(dual active bridge,DAB)与VSC耦合运行下故障响应特性,建立多场景故障等效回路。其次,从故障电流多阶段暂态响应过程出发,建立故障前初始稳态阶段、直流母线放电阶段、二极管续流阶段与故障后稳态阶段的故障电流计算模型。然后,基于所建多阶段故障电流计算模型,分析影响故障峰值电流的关键因素。最后,以含多分布式能源的多端直流配电网为例,将理论计算结果与Matlab/Simulink仿真结果对比,验证所提模型的准确性。 展开更多
关键词 多端直流配电网 分布式能源 故障等效回路 故障电流计算 峰值电流
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