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Functional characterization of OsLT9 in regulating rice leaf thickness 认领 引用
1
作者 Jian Wang Dagang Chen +9 位作者 Haifei Hu Yamei Ma Tifeng Yang Jie Guo Ke Chen Chanjuan Ye Juan Liu Xinqiao Zhou Chuanguang Liu Junliang Zhao 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2026年第2期223-233,共11页
Leaf thickness in rice critically influences photosynthetic efficiency and yield,yet its genetic basis remains poorly understood,with few functional genes previously characterized.In this study,we employ a pangenome-w... Leaf thickness in rice critically influences photosynthetic efficiency and yield,yet its genetic basis remains poorly understood,with few functional genes previously characterized.In this study,we employ a pangenome-wide association study(Pan-GWAS)on 302 diverse rice accessions from southern China,identifying 49 quantitative trait loci(QTLs)associated with leaf thickness.The most significant locus,qLT9,is fine-mapped to a 79-kb region on chromosome 9.Transcriptomic and genomic sequence analyses identify LOC_Os09g33480,which encodes a protein belonging to Multiple Organellar RNA Editing Factor family,as the key candidate gene.Overexpression and complementation transgenic experiments confirm LOC_Os09g33480(OsLT9)as the functional gene underlying qLT9,demonstrating a 24-bp Indel in its promoter correlates with the expression levels and leaf thickness.Notably,OsLT9 overexpression lines show not only thicker leaf,but also significantly enhanced photosynthetic efficiency and grain yield,establishing a link between leaf thickness modulation and yield enhancement.Population genomic analyses indicate strong selection for OsLT9 during domestication and breeding,with modern cultivars favoring thick leaf haplotype of OsLT9.This study establishes OsLT9 as a key regulator controlling leaf thickness in rice,and provides a valuable genetic resource for molecular breeding of high-yielding rice through optimization of plant architecture. 展开更多
关键词 Rice Leaf thickness GWAS Functional gene OsLT9
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A Coupled Elastohydrodynamic-Acoustic Framework for High-Resolution Ultrasonic Measurement of Dynamic Film Thickness in Lubricated Contacts 认领 引用
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作者 Pan Dou Yayu Li +5 位作者 Suhaib Ardah Tonghai Wu Min Yu Thomas Reddyhoff Yaguo Lei Daniele Din 《Engineering》 SCIE EI CSCD 2026年第3期291-301,共11页
The thickness of the lubricating film plays a vital role in the operational efficiency and reliability of rolling bearings.Ultrasonic reflection techniques offer a promising noninvasive approach for the in situ evalua... The thickness of the lubricating film plays a vital role in the operational efficiency and reliability of rolling bearings.Ultrasonic reflection techniques offer a promising noninvasive approach for the in situ evaluation of lubricant films.However,accurate identification of the central film thickness remains challenging because of several complex factors,which include dynamic fluctuations,localized elastic deformation,cavitation effects,and variations in the oil supply.In this study,a comprehensive theoretical and numerical framework for elucidating the effects of these factors on ultrasonic wave propagation in lubricated contacts is presented.Numerical simulations in which the elastohydrodynamic lubrication(EHL)regime and cavitation-induced effects are considered are carried out to obtain surface deformation profiles and identify cavitation regions.High-fidelity acoustic simulations are subsequently conducted to interpret the reflected ultrasound data.The reflection coefficient distribution exhibits a symmetric"double peak with central valley"pattern that is induced by the combined effect of the contact geometry and the EHL-induced oil film thickness distribution.Cavitation causes the central valley to shift toward the inlet region and increases the reflection coefficient.Accordingly,the central film thickness is extracted from the distribution of the reflection coefficient under different operating conditions.Experimental validation using both glass-oil-steel and steel-oil-steel bearing setups confirms the effectiveness of the proposed method.The high-resolution fluorescence measurement that is adopted in the glassoilsteel configuration validates the simulation of the reflection coefficient distribution.Furthermore,theoretical EHL calculations are performed for the steeloilsteel configuration to validate the measurement accuracy for the central oil film thickness. 展开更多
关键词 Rolling bearing Central film thickness Ultrasonic measurement Elastohydrodynamic lubrication Cavitation
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Optimization control of transverse thickness difference of silicon steel based on interpretable machine learning 认领 引用
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作者 Hao-Tang Qie An-Rui He +7 位作者 Mei-Tao Jiang Ting-Song Yang Chao Liu Jing-Dong Li Zi-Ming Gao Yong Wang Qing-Xiao Feng Hua-Long Li 《Journal of Iron and Steel Research International》 SCIE EI CSCD 2026年第6期325-349,共25页
Transverse thickness difference is a key indicator for evaluating the quality of cold-rolled silicon steel products,jointly determined by hot-rolled silicon steel data and cold rolling process parameters.However,there... Transverse thickness difference is a key indicator for evaluating the quality of cold-rolled silicon steel products,jointly determined by hot-rolled silicon steel data and cold rolling process parameters.However,there are“process barriers”and“data islands”between different production lines,resulting in low accuracy and poor interpretability.In addition,the transverse thickness difference mainly relies on manual sampling measurement.The lag and uncertainty of the measurement results lead to a lack of effective online control methods.To overcome this,a cold-rolled silicon steel transverse thickness difference control framework based on interpretable machine learning is proposed.First,a hot-cold rolling cross-process data platform is established to match and integrate multivariate data from different production lines,providing a data foundation.Then,an RUN-HLSSVM-AdaBoost model prediction model combining Runge-Kutta algorithm optimized hybrid kernel least squares support vector machine and AdaBoost ensemble modeling method is established.Afterward,the adaptive bandwidth kernel density estimation improved by local weighting strategy is used to construct a prediction interval,which characterizes the uncertainty of the prediction results.SHAPley Additive exPlanations interpretable method is used to break the“black box”limitation and reveal the influence of hot and cold rolling parameters on the transverse thickness difference,and finally,an online control strategy is proposed.Industrial experiments have verified the effectiveness of the above framework,and the transverse thickness difference has been significantly improved,which provides a new paradigm for solving the problem of online control of transverse thickness difference of cold-rolled silicon steel. 展开更多
关键词 Silicon steel Transverse thickness difference Interpretable machine learning Point-interval prediction Online control
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Variations in effective elastic thickness and tectonic interpretation of the Northeast Pacific 认领 引用
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作者 Long MA An YANG +4 位作者 Chenguang LIU Quanshu YAN Zhaocai WU Chongzhi DONG Haibin SONG 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2026年第4期1453-1468,共16页
A Moho topography admittance method with high-precision Moho depth inversion for calculating the effective elastic thickness(Te)of the oceanic lithosphere was established by comprehensively considering the effects ... A Moho topography admittance method with high-precision Moho depth inversion for calculating the effective elastic thickness(Te)of the oceanic lithosphere was established by comprehensively considering the effects of surface and subsurface loading.The accuracy of the method was verified through model testing and applied to the Northeast Pacific region.Te values in the study area range from 5 to 60 km,showing distinct spatial variations:regions with fracture zones such as Sedna,Surveyor,and Mendocino exhibit Te values generally<20 km.In thermally anomalous regions,the predictive capability of the standard thermal cooling model is significantly limited.Mantle plume-induced thermal anomalies disrupt the expected correlation between current heat flow and lithospheric age,resulting in a minimal correlation between Te and contemporary heat flow measurements.Earthquake distribution analysis shows that seismic events(M≥4)in the study area are concentrated within a Te of 10-60 km,of which 20% occur at Te values of 25-30 km.The Te-loading-age relationship along the Hawaii-Emperor Seamount Chain shows partial consistency with the standard thermal cooling model:in the Hawaii Ridge region,a synchronous decrease of Te with loading age;in the Emperor Seamount region,Te decreases from 47 to 10 km as the loading age decreases from 90 to 30 Ma,with a considerably lower slope than that of the Hawaii Ridge.However,the central seamounts exhibit an anomalous increase in Te(1-22 km),significantly deviating from the standard model.This study reveals that Te values cannot be predicted solely based on loading age,but are jointly influenced by multiple physical mechanisms including regional tectonic history,thermotectonic age,and crust-mantle decoupling induced by mantle plume thermal anomalies.In thermally anomalous regions,the applicability of the standard thermal cooling model is significantly limited,and predictions of lithospheric strength require region-specific corrections based on the regional tectonic background. 展开更多
关键词 Northeast Pacific effective elastic thickness(Te) lithosphere Moho undulation sliding window admittance
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Probing the Neutron-Skin Thickness Through J/ψPhotoproduction in Ultra-Peripheral Collisions 认领 引用
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作者 Haoyuan Li Lu-Meng Liu +2 位作者 Jinhui Chen Yu-Gang Ma Chunjian Zhang 《Chinese Physics Letters》 SCIE EI CAS CSCD 2026年第5期1-8,共8页
We study the impact of neutron-skin thickness on J/ψphotoproduction in ultra-peripheral208Pb+208Pb collisions.Within the color glass condensate framework,we calculate coherent and incoherent cross sections and ... We study the impact of neutron-skin thickness on J/ψphotoproduction in ultra-peripheral208Pb+208Pb collisions.Within the color glass condensate framework,we calculate coherent and incoherent cross sections and examine their dependence on the momentum transfer|t|for different neutron-skin thicknesses.We find a clear imprint of the neutron skin on the|t|spectra:a larger neutron skin leads to a smoother and more extended colordensity profile,suppressing the coherent cross section at large|t|while enhancing the incoherent cross section through increased event-by-event configurational fluctuations in the nuclear periphery.We further show that the ratio of incoherent to coherent integrated cross sections provides a particularly sensitive and robust observable,with reduced theoretical uncertainties.These results establish diffractive vector-meson photoproduction in ultraperipheral collisions as a powerful tomographic tool to constrain the neutron-skin thickness and the transverse gluon distribution at the LHC and future electronśion colliders. 展开更多
关键词 color glass condensate frameworkwe coherent incoherent cross sections j photoproduction coherent cross section ultra peripheral collisions color glass condensate neutron skin thickness colordensity profilesuppressing
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Association between choroidal thickness and primary open angle glaucoma in highly myopic eyes 认领 引用
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作者 Pei-Yao Jin Min Tang +6 位作者 Min-Wen Zhou Ying Fan Yu-Ye Ling Jian-Feng Zhu Hai-Dong Zou Jiang-Nan He Wen-Wen Xue 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2026年第6期1088-1095,共8页
AIM:To investigate the relationship between choroidal thickness(CT)and primary open angle glaucoma(POAG)in highly myopic eyes across different categories of myopic atrophic maculopathy(MAM).METHODS:This observational ... AIM:To investigate the relationship between choroidal thickness(CT)and primary open angle glaucoma(POAG)in highly myopic eyes across different categories of myopic atrophic maculopathy(MAM).METHODS:This observational analytical case–control study enrolled highly myopic patients.All participants underwent comprehensive ophthalmic examinations.CT was measured in peripapillary and macular regions using optical coherence tomography(OCT).Each eye was classified for POAG status and MAM category.Stepwise logistic regression was performed to identify factors independently associated with POAG.RESULTS:Among 248 highly myopic subjects,37(18 males,mean age 68.25±7.16y)had POAG(25 bilateral,12 unilateral)and 211(97 males,mean age 67.09±7.63y)were non-glaucomatous.Age and sex did not differ significantly between groups(both P>0.05).Seventy-eight patients had unilateral high myopia and 170 bilateral,yielding 418 highly myopic eyes,of which 58(13.88%)had POAG.POAG prevalence across MAM categories(no lesion to complete macular atrophy)was 7.14%,16.28%,14.07%,17.86%,and 17.14%,respectively(P=0.44).In the diffuse chorioretinal atrophy subgroup,POAG eyes showed significantly thicker CT in central,inner nasal,outer superior,inner superior,and inner inferior macular regions,and thinner central corneal thickness(all P<0.05).Stepwise logistic regression showed that only parafoveal inferior CT was independently associated with POAG in this subgroup(OR=1.017;95%CI:1.005–1.028;P<0.01).No significant CT–POAG association was found in other MAM categories.CONCLUSION:Increased macular CT is independently associated with POAG in highly myopic eyes with diffuse chorioretinal atrophy.This implies distinct pathogenic mechanisms underlying POAG development across different MAM categories in high myopia. 展开更多
关键词 glaucoma primary open angle glaucoma choroidal thickness high myopia myopic atrophic maculopathy
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Prediction method of deep CBM reservoir thickness based on improved XGBoost 认领 引用
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作者 Huang Ya-ping Qi Xue-mei +1 位作者 Cheng Yan Zhou Ling-ling 《Applied Geophysics》 SCIE CSCD 2026年第2期507-516,865,共10页
Accurate prediction of coal seam thickness is the core geological basis for deep CBM(Coalbed methane)reservoir resource evaluation,sweet spot optimization and efficient development deployment.This study takes the seis... Accurate prediction of coal seam thickness is the core geological basis for deep CBM(Coalbed methane)reservoir resource evaluation,sweet spot optimization and efficient development deployment.This study takes the seismic forward modeling section of the geological model of deep CBM reservoir as the research object,constructs a data set of 100 groups of effective samples,and proposes an improved XGBoost(Extreme gradient boosting)model based on GWO(Grey wolf optimization)algorithm to carry out the research on the prediction method of deep CBM reservoir thickness.The results show that the improved model has higher prediction accuracy.Under the condition of noise,the determination coeffi cient R²of coal thickness prediction can reach 0.967,which is 0.131 higher than the conventional XGBoost algorithm,and the prediction accuracy is signifi cantly improved.The improved model is applied to the coal thickness prediction of the actual seismic data,and the results are in good agreement with the coal seam information exposed by the existing boreholes.The minimum absolute error of the predicted coal thickness is 0.36 m,and the maximum absolute error is 1.47 m,which verifi es the feasibility and eff ectiveness of the improved XGBoost algorithm in the prediction of the thickness of deep CBM reservoir.The research results can provide important technical support for the effi cient development and utilization of deep CBM reservoirs. 展开更多
关键词 deep CBM reservoir coal thickness prediction XGBoost GWO seismic attribute
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Wall Thickness Homogenization Control and Performance of Superplastically Formed Hemispherical Shell of TC4 Titanium Alloy 认领 引用
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作者 Ji Wei Zhang Zhaohuang +3 位作者 Lu Zichuan Wei Shi Qiu Xuyangfan Zhang Xuhu 《稀有金属材料与工程》 SCIE EI CAS CSCD 北大核心 2026年第7期1683-1691,共9页
Spherical and capsule-shaped surface tension tanks are widely used in satellite,spacecraft,and other fields due to their advantages of lightweight structure,high efficiency,and high reliability.With the advancement of... Spherical and capsule-shaped surface tension tanks are widely used in satellite,spacecraft,and other fields due to their advantages of lightweight structure,high efficiency,and high reliability.With the advancement of space exploration,the demands for thinner walls,more complex structures,and uniform overall performance in the hemispherical shells of these tanks present significant challenges for hemispherical shell forming technique.A hemispherical shell with uniform wall thickness was prepared using the rapid direct-and-reverse superplastic forming method.Results reveal that the properties and microstructure of each section of the formed hemisphere shell are consistent with those of the initial plate,and the overall shell thickness is highly uniform. 展开更多
关键词 hemispherical shell of storage tank control of wall thickness direct-and-reverse superplastic forming mold design
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Machine-learning models for classification of mudcake thickness in oil-based drilling fluids 认领 引用
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作者 Shadfar Davoodi Grachik Eremyan +2 位作者 Amir H.Mohammedi Mohammed Al-Shargabi Evgeny Burnaev 《Natural Gas Industry B》 2026年第2期206-227,共22页
The performance of oil-based drilling fluids(OBDFs)is critical for maintaining drilling efficiency under conditions in which water-based fluids fail to perform effectively.Mudcake or filtercake thickness(MCT)is a key ... The performance of oil-based drilling fluids(OBDFs)is critical for maintaining drilling efficiency under conditions in which water-based fluids fail to perform effectively.Mudcake or filtercake thickness(MCT)is a key property of OBDFs because it directly influences wellbore stability and the extent of formation damage.Conventional methods for determining MCT rely on manual laboratory measurements that are time-consuming and cannot represent real-time downhole conditions,thereby limiting their value for operational decision-making and motivating the development of reliable predictive methods.This study proposes a novel framework for the near-real-time classification of MCT in OBDF systems.A comprehensive field dataset was compiled from five routinely measured,rapidly acquired laboratory parameters:mud weight,temperature,alkalinity,emulsion stability,and Marsh funnel viscosity.Four machine-learning classifiers-extreme gradient boosting(XGB),support vector machine,extreme learning machine,and multi-layer perceptron-were developed to classify MCT into three operationally meaningful categories:Excellent(≤1.0 mm),Good(1.0-2.2 mm),and Poor(>2.2 mm).The developed models achieved high classification accuracy,with the XGB algorithm demonstrating the most stable and reproducible performance(test accuracy:0.98,F1-score:0.98).Comprehensive evaluation-including receiver operating characteristic analysis,model confidence assessment,learning curves,group K-fold cross-validation,and external validation-confirmed the strong generalization capability of the XGB model,which achieved 94.81% accuracy when applied to completely unseen wells.Interpretability analysis using SHapley Additive exPlanations(SHAP)identified emulsion stability as the dominant predictive feature and revealed that parameter interactions(e.g.,alkalinity-emulsion stability)vary dynamically across different MCT classes.The primary innovation of this study lies in reframing MCT prediction as a multi-class classification problem rather than a traditional regression task,enabling rapid and actionable interpretation of drilling fluid performance.The proposed framework provides a semiautomated,data-driven tool for near-real-time monitoring of MCT in OBDF systems,reducing reliance on slow laboratory measurements and supporting timely operational decisions that improve drilling efficiency and preserve wellbore integrity in complex drilling environments. 展开更多
关键词 Mudcake thickness Oil-based muds Extreme gradient boosting machine-learning modeling Drilling fluids
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A multi-tie points-based method for retrieving of the Arctic thin sea ice thickness from SMOS 认领 引用
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作者 LI Jiaxing ZHANG Shengkai +2 位作者 XIAO Feng GENG Tong LI Fei 《Advances in Polar Science》 CSCD 2026年第1期43-55,共13页
The correlation between the Soil Moisture and Ocean Salinity(SMOS)L-band brightness temperature and thin sea ice thickness has been widely exploited using semi-empirical retrieval approaches based on a single-tie poin... The correlation between the Soil Moisture and Ocean Salinity(SMOS)L-band brightness temperature and thin sea ice thickness has been widely exploited using semi-empirical retrieval approaches based on a single-tie point(STP).However,due to pronounced spatial heterogeneity in seawater and sea ice properties across the Arctic,the use of an STP often leads to regionally biased.To address this limitation,this study proposes a multi-tie point(MTP)sea ice thickness retrieval method based on SMOS brightness temperature and sea ice concentration time series.Multiple seawater and sea ice tie-point values are identified through point-by-point time series analysis,quality control,and statistical hypothesis testing,allowing spatial variability in radiometric properties to be explicitly considered.The MTP-based retrieval is applied to Arctic freeze-up conditions.Validation against independent SMOS thin sea ice thickness products shows that the MTP approach yields significantly reduced bias and root mean square error compared with the conventional STP method,with statistically significant improvements confirmed by paired t-tests.While retrieval accuracy stabilizes beyond a certain number of tie points,the preprocessing cost associated with tie-point selection increases substantially.Considering both accuracy and efficiency,the MTP framework provides a practical and robust approach for large-scale Arctic thin sea ice thickness retrieval and enables improved characterization of regional freezing processes and maximum ice thickness. 展开更多
关键词 SMOS single-tie point Arctic multi-tie point thin sea ice thickness
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Theoretical model and numerical simulation research on minimum overburden thickness of TBM excavation based on surrounding rock arching theory 认领 引用
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作者 ZHOU Zhong SUI Yuchao YAN Haitao 《Journal of Southeast University(English Edition)》 EI CAS 2026年第1期12-25,共14页
Based on the surrounding rock arching and hingeless arch structure theories,a theoretical formula for the minimum overburden thickness was derived.By substituting different mechanical parameters of multiple tunnels at... Based on the surrounding rock arching and hingeless arch structure theories,a theoretical formula for the minimum overburden thickness was derived.By substituting different mechanical parameters of multiple tunnels at home and abroad into this formula,minimum self-supporting arch formulas under different surrounding rock classes were obtained.Based on the actual engineering case of a dual-mode shield tunnel,a numerical model for the tunnel boring machine excavation mode was established to verify the theoretical formulas.Next,three surrounding rock classes,four soil layer thickness gradients,and twelve overburden thickness gradients were designed,resulting in 144 models formed by the combination of the three factors.Uniform tests were conducted,and the pressure arch heights under different surrounding rock classes were obtained.The results show that in the theoretical formulas,the tunnel radius has a linear positive correlation with the pressure arch height,while the tunnel depth has a linear positive correlation with the square of the pressure arch height.According to numerical simulation results,the pressure arch height increases with the increase of the overburden thickness and then tends toward a critical value of twice the tunnel diameter.Finally,the results of the numerical model are in good agreement with those calculated using the theoretical formulas,verifying the rationality of the established theoretical formulas. 展开更多
关键词 minimum overburden thickness tunnel boring machine(TBM) pressure arch numerical simulation self-supporting arch
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Effective Elastic Thickness of the Lithosphere in North China and Its Geodynamic Implications 认领 引用
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作者 Yu-hang Pan Hao Chen +1 位作者 Xiao-yuan Xu Ke Xu 《Applied Geophysics》 SCIE CSCD 2026年第2期681-692,869,870,共12页
The eff ective elastic thickness(Te)of the lithosphere serves as a critical parameter for characterizing the mechanical strength and structural response of the lithosphere.In this study,Te and the initial load r... The eff ective elastic thickness(Te)of the lithosphere serves as a critical parameter for characterizing the mechanical strength and structural response of the lithosphere.In this study,Te and the initial load ratio(F)were jointly estimated for the North China Craton and its surrounding regions using a combined admittance–coherence inversion approach within a Bayesian framework,incorporating Markov Chain Monte Carlo(MCMC)sampling to quantify parameter uncertainties.The results reveal signifi cant lateral variations in Te across the study area,ranging from 5 to 66 km.High Te values(30–66 km)are observed beneath the Ordos Block,indicating a stable and mechanically strong lithosphere.In contrast,the North China Block exhibits low Te values(5–25 km),suggesting lithospheric thinning and mechanical weakening.These fi ndings are further supported by seismicity patterns,lithosphere–asthenosphere boundary(LAB)depth,and mantle composition(Mg#),all of which demonstrate a strong correlation between Te and lithospheric structure and dynamic processes.Low-Te regions are associated with high seismic activity and a“thin–hot–weak”lithospheric signature,whereas high-Te regions exhibit a“thick–cold–strong”stable configuration.It is proposed that the destruction of the North China Craton has been primarily driven by asthenospheric thermal perturbation,following a geodynamic evolution involving“thermal disturbance–lithospheric thinning–compositional modification–mechanical weakening.”This study provides new mechanical constraints on the geodynamic processes responsible for craton destruction. 展开更多
关键词 Effective elastic thickness Gravity anomaly Lithospheric flexure
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Long-term observation of the endothelium morphology and corneal thickness in myopic adolescents treated with orthokeratology:a 10-year retrospective study 认领 引用
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作者 Li-Qiong Zhao Zi-Xun Wang +5 位作者 Ying Li Bi-Ying Wang Bei Du Jane Beeman Rui-Hua Wei Lin Liu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2026年第5期939-944,共6页
AIM:To assess the long-term safety of orthokeratology(ortho-k)in myopic children by evaluating changes in corneal endothelial morphology and central corneal thickness(CCT)after prolonged ortho-k lens wear.METHODS:This... AIM:To assess the long-term safety of orthokeratology(ortho-k)in myopic children by evaluating changes in corneal endothelial morphology and central corneal thickness(CCT)after prolonged ortho-k lens wear.METHODS:This study included 65 myopic children(130 eyes).The ortho-k group comprised 39 children who had worn ortho-k lenses for more than 10y.The control group included 26 children who wore single-vision spectacles for myopia correction.Clinical data and adverse events were documented throughout the follow-up period.Endothelial cell density(ECD),coefficient of variation(CV)of cell area,percentage of hexagonal cells(%SIX),and CCT were measured at baseline and at the final follow-up visit.RESULTS:The 39 participants(18 males,21 females)enrolled in the ortho-k group completed the 10-year follow-up examinations successfully.The ages ranged from 7 to 12(9.24±1.26)y.In the control group,26 participants(13 males,13 females)were successfully recalled and completed their 10th year examinations.The ages ranged from 7 to 12(9.62±1.68)y.In the ortho-k group,ECD was 3119.86±202.07 cells/mm2at baseline and 3057.42±264.52 cells/mm2at the 10-year follow-up(P=0.058).CV was 30.78%±6.70%and 32.45%±7.87%(P=0.053).%SIX was 62.23%±13.07%and 60.31%±11.59%(P=0.234).CCT decreased by 8±4μm at the 6-month visit and remained stable thereafter(538.85±43.61μm at 6mo vs 540.78±41.44μm at 10y,P=0.528).At the 10-year follow-up,no significant between-group differences were observed in ECD,CV,%SIX,or CCT(all P>0.05).CONCLUSION:This 10-year retrospective study demonstrates that long-term ortho-k lens wear has no significant adverse effects on corneal endothelial morphology or CCT compared with spectacle wear.Ortho-k shows excellent long-term safety with regard to corneal endothelial parameters and CCT,comparable to that of conventional spectacle correction in myopic children. 展开更多
关键词 myopia or thokeratology corneal endothelium morphology central corneal thickness percentage of hexagonal cells long-term safety
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Comparison of carotid intima-media thickness between hemodialysis and peritoneal dialysis patients 认领 引用
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作者 Nur Samsu Mala Hayati +1 位作者 Eden Suryoiman Winoto Hani Susianti 《World Journal of Nephrology》 2026年第2期195-202,共8页
BACKGROUND Patients with chronic kidney disease(CKD)are at high risk of developing cardiovascular disease(CVD).Carotid intima-media thickness(cIMT)is a strong predictor of CVD.Klotho has been associated with increased... BACKGROUND Patients with chronic kidney disease(CKD)are at high risk of developing cardiovascular disease(CVD).Carotid intima-media thickness(cIMT)is a strong predictor of CVD.Klotho has been associated with increased atherosclerotic plaque stability in CKD patients.AIM To investigate the association between dialysis modality and cIMT in dialysis patients.METHODS A cross-sectional study of 83 dialysis patients,40 hemodialysis(HD)patients and 43 peritoneal dialysis(PD)patients,who met the inclusion criteria.Anamnesis,carotid artery ultrasonography(USG),and laboratory tests were performed on all patients.cIMT measurements were performed in 6 carotid territories using arterial USG.RESULTS PD patients had lower cIMT[0.53(0.47;0.67)vs 0.63(0.54;0.70);P=0.005].Younger age in PD patients was independently associated with lower cIMT(β=0.006;P=0.003).PD patients had a lower FGF23/Klotho ratio compared to HD patients[26.26(13.32;69.45)vs 67.34(16.56;131.35);P=0.039].Similarly,in PD patients,a moderate positive correlation was found between calcium,phosphorus,and CaxP product levels with fibroblast growth factor 23(FGF-23)levels.However,the strength of the correlation was reduced when correlated with the FGF-23/Klotho ratio.CONCLUSION This study showed that PD patients have lower cIMT than HD patients.Younger age was independently associated with lower cIMT.On the other hand,FGF-23 and the FGF-23/Klotho ratio were significantly positively correlated with CaxP product in PD patients,but not in HD patients.Klotho reduces the strength of this correlation,thus appearing play an important role in the lower cIMT in these PD patients. 展开更多
关键词 Calcium Phosphorus Carotid artery intima-media thickness Fibroblast growth factor 23/Klotho ratio Peritoneal dialysis
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Modeling and Characterization of Residual Stress Distribution of Thin Film/Substrate Structure with Non-negligible Film Thickness from Morphology 认领 引用 被引量：1
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作者 Kunjie Sun Chen Sun Jubing Chen 《Acta Mechanica Solida Sinica》 SCIE EI CSCD 2026年第6期755-765,共11页
Thin film/substrate structures are irreplaceable in many advanced devices,and their reliability is highly dependent on the distribution of residual stress.Stoney’s formula is extensively used to analyze residual stre... Thin film/substrate structures are irreplaceable in many advanced devices,and their reliability is highly dependent on the distribution of residual stress.Stoney’s formula is extensively used to analyze residual stress of thin film/substrate structure because of its simplicity and convenience,but it encounters difficulties when considering the film thickness and arbitrary residual stress.In this paper,the arbitrarily deformed film/substrate structure is modeled and characterized;hence,the full-field distribution of residual stress considering film thickness can be calculated directly from the morphology.Based on the theory of elasticity,seven governing equations including displacements,interfacial shear stresses,and residual stresses are established.Parameterization and method of constant variation are used to decouple the equation variables,and results of residual stress are expressed by Fourier series.By excavating the coordination relationships of curvature within three directions and releasing local parameter series terms,the expressions of residual stresses reduce computational complexity.The convergence of Fourier series and the order of emphasis are calculated by a randomly generated displacement field.The effectiveness and efficiency of the theory are verified by the finite element method,and the results are compared with those of ignoring film thickness.The results demonstrate the necessity of accounting for the film thickness,which is of great significance to the measurement of residual stress of thin film/substrate structures. 展开更多
关键词 Residual stress Thin film/substrate Non-negligible film thickness Stress-curvature relations Full-field curvature Finite element method
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Effects of modulation layer thickness on microstructures and mechanical behavior of VN/TiN−Ni nano-multilayered films 认领 引用
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作者 Wen-jie CHENG Ping LIU +4 位作者 Xin-fa ZHU Yi MENG Hong-mei LU Peter K.LIAW Wei LI 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2026年第2期586-599,共14页
The dependence of interface structure and mechanical properties on the modulation layer thickness of VN/TiN−Ni nano-multilayered films deposited on Si substrates using a reactive magnetron sputtering technique was sys... The dependence of interface structure and mechanical properties on the modulation layer thickness of VN/TiN−Ni nano-multilayered films deposited on Si substrates using a reactive magnetron sputtering technique was systematically investigated. The films were characterized using X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy, transmission electron microscopy, and nanoindentation. The results show that the TiN−Ni layer grows epitaxially on the VN layer, forming a coherent interface between the two sublayers. When the deposition time ratio of the two sublayers (TTiN−Ni꞉TVN) is 10꞉12, the films exhibit remarkable mechanical properties, with hardness, elastic modulus, and fracture toughness values of 25.9 GPa, 317 GPa, and 1.88 MPa·m1/2, respectively. Meanwhile, fracture toughness is improved by approximately 50% compared to the VN monolithic film. This enhancement is attributed to the coherent interface between the sublayers and the phase separation in the TiN−Ni layer. 展开更多
关键词 nano-multilayered film modulation-layer thickness phase separation strengthening fracture toughness
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Tolerance-constrained inverse design of ceramic core configuration for precision wall thickness control in hollow turbine blades 认领 引用
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作者 Zi-chun Wang Wen-hu Wang +3 位作者 Kang Cui Rui-song Jiang Rui-zhe Dong Yuan-bin Wang 《China Foundry》 SCIE EI CAS CSCD 2026年第4期599-612,共14页
Wall thickness deviation significantly diminishes the durability and efficiency of turbine blades.It primarily results from surface deformation and positional shifts of the ceramic core during casting,which disrupts c... Wall thickness deviation significantly diminishes the durability and efficiency of turbine blades.It primarily results from surface deformation and positional shifts of the ceramic core during casting,which disrupts core-shell alignment.A novel reverse adjustment method for ceramic core positions within turbine blades based on the measurement of a batch of blades was proposed in this work.Initially,the optimal position solution model for internal ceramic cores of turbine blades on the basis of industrial computed tomography(ICT)scanning was established.Subsequently,a reverse adjustment method was developed to optimize the position and orientation of ceramic cores within the blade interior.The proposed method was verified through casting experiments,revealing a reduction of 45.5%in the maximum wall thickness error of the adjusted blades compared to their initial condition.The wall thickness error at the leading and trailing edges of the blade is reduced to less than±0.15 mm,while the wall thickness error on the concave and convex surfaces is minimized to less than±0.2 mm,which essentially satisfies the prescribed wall thickness tolerance requirements.The process system for precise shape control of hollow turbine blade wall thickness is further refined,providing robust technical support for enhancing the conformity rate of hollow turbine blade wall thickness dimensions. 展开更多
关键词 hollow turbine blade tolerance-constrained wall thickness control reverse adjustment model alignment
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Nonlinear free vibrations of functionally graded graphene origami-enabled auxetic metamaterial skew-microplates with variable thickness using isogeometric analysis 认领 引用
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作者 Vu Ngoc Anh Tran Van Ke +2 位作者 Nguyen Thi Thu Huong Nguyen Thi Hue Pham Hoang Tu 《Defence Technology（防务技术）》 SCIE EI CAS CSCD 2026年第3期85-108,共24页
The remarkable mechanical and physical characteristics of functionally graded(FG)graphene origami(GOri)-enabled auxetic metamaterial(GOEAM)structures,including their high strength-to-weight ratio,tunable stiffness and... The remarkable mechanical and physical characteristics of functionally graded(FG)graphene origami(GOri)-enabled auxetic metamaterial(GOEAM)structures,including their high strength-to-weight ratio,tunable stiffness and strength,and negative Poisson's ratio(NPR),have demonstrated significant promise for a range of engineering applications.This paper aims to investigate the nonlinear free vibrations behaviors of FG-GOEAM non-uniform thickness skew-microplate with rectangular and elliptical planform and resting on Kerr-elastic foundation in thermal environment.Within the framework of the higher-order shear deformation theory(HSDT),von Kármán assumption,modified couple stress theory(MCST)and by employing Hamilton's principle the nonlinear governing equations of motion are established.By combining an iterative technique with a displacement control strategy,an isogeometric analysis(IGA)approach used to determine the nonlinearity in free vibration,as measured by the nonlinear frequency ratio associated with the center deflection amplitude.The effects of GOri distribution patterns,weight fraction,length-scale parameter,temperature difference,skew-angle,and micro-plate dimensions on the nonlinear free vibrations behaviors of the FG-GOEAM non-uniform thickness skew-microplate are revealed through a thorough parametric study.This result can be applied in studies on the design of micro-electro-mechanical devices operating in various complex environments and conditions. 展开更多
关键词 Nonlinear free vibration FG-GOEAM skew-microplate Isogeometric analysis Non-uniform thickness Modified couple stress theory
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Free vibration of hinged FG-GPLRC magneto-electro-elastic variable-thickness folded trapezoidal sandwich panels 认领 引用
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作者 Yuangen Wan Shaowu Yang +2 位作者 Ran An Zhiquan Wang Hailong Yang 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第4期85-109,共25页
This study presents an integrated approach to investigate the free vibration characteristics of variable-thickness,seamless,hinge-folded trapezoidal sandwich panels with magneto-electro-elastic face sheets and a funct... This study presents an integrated approach to investigate the free vibration characteristics of variable-thickness,seamless,hinge-folded trapezoidal sandwich panels with magneto-electro-elastic face sheets and a functionally graded graphene platelet-reinforced composite core.The design leverages the excellent mechanical strength,high electrical conductivity,and lightweight properties of graphene,while considering multi-field coupling effects among elastic,thermal,electrical,and magnetic fields.The incorporation of hinge mechanisms significantly enhances structural flexibility and adaptability,enabling position-specific morphing under different operational conditions,thereby optimizing stress distribution and improving reliability.An enhanced Halpin-Tsai method is employed to accurately characterize composite material properties.Nonlinear equations are derived via the first-order shear deformation theory and Hamilton’s principle,comprehensively accounting for shear deformation,rotatory inertia,and providing a rigorous theoretical basis for motion equations.Double trigonometric series approximation combined with Galerkin’s method is used to calculate the natural frequencies.Through systematic analysis,the study reveals how key geometrical parameters,material properties,and thickness variations impact the intrinsic frequency.This work not only provides insights into the theoretical aspects of advanced smart composite structures but also provides practical guidelines for optimizing design parameters related to geometry,material selection,and thickness distribution.The proposed methodology offers potential applications in aerospace,micro-electromechanical systems,and other adaptive structural systems. 展开更多
关键词 Magneto-electro-elastic properties Variable thickness trapezoidal plate Free vibration analysis FGGPLRC Seamless hinge
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Measurement of the equivalent complex permittivity of electromagnetic structural materials without prior thickness 认领 引用
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作者 Xiang-Bao Zhu Yun-Peng Zhang +7 位作者 Pin-Hong Xie Yi-Hang Tu Jia-Wei Long Xue Niu Chong Gao Cheng-Yong Yu Yong Gao En Li 《Chinese Physics B》 SCIE EI CAS CSCD 2026年第4期202-212,共11页
Electromagnetic structural materials exhibit significant sensitivity to the polarization state and incidence angle of electromagnetic waves.The equivalent complex permittivity is the core parameter that describes the ... Electromagnetic structural materials exhibit significant sensitivity to the polarization state and incidence angle of electromagnetic waves.The equivalent complex permittivity is the core parameter that describes the dielectric properties of electromagnetic structural materials.Therefore,accurate characterization of their equivalent complex permittivity is essential for establishing electromagnetic models and guiding the design of functional devices.This paper proposes a broadband inversion method based solely on reflection measurements at different incident polarizations and incident angles.By establishing a set of adaptive equations for multi-reflection measurement states under oblique incidence,the proposed method directly resolves the equivalent complex permittivity without requiring prior knowledge of the sample thickness and iterative phase unwrapping,and obtains broadband measurement results in a single measurement.The simulation and experimental results show that this method has good testing consistency and accuracy.This study provides a highprecision,low-cost and efficient testing solution for dielectric property evaluation of electromagnetic structural materials.It can simplify the complex modeling design of electromagnetic structural materials into an equivalent single-layer material design,providing a reference value for rapid analysis of the scattering characteristics of complex structures. 展开更多
关键词 equivalent complex permittivity electromagnetic structural materials broadband thickness unknown
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