The management of severe tricuspid regurgitation(TR)in elderly patients has been transformed by transcatheter edge-to-edge repair(TEER),now a cornerstone for those at prohibitive surgical risk.[1]However,with increasi...The management of severe tricuspid regurgitation(TR)in elderly patients has been transformed by transcatheter edge-to-edge repair(TEER),now a cornerstone for those at prohibitive surgical risk.[1]However,with increasing procedural volumes,recurrent TR after TEER is emerging as a relevant clinical challenge.[2]Although three-dimensional(3D)echocardiography provides superior characterization of complex post-procedural orifices,its role in guiding the difficult decision between redo intervention and conservative management in octogenarians remains insufficiently defined.[3,4]展开更多
Since 2016,the number of clinical trials registered in the World Health Organization-International Clinical Trials Registry Platform has been steadily increasing.The number of clinical trials registered between 2018 a...Since 2016,the number of clinical trials registered in the World Health Organization-International Clinical Trials Registry Platform has been steadily increasing.The number of clinical trials registered between 2018 and 2022 is 39765 for BRICS countries.Though India’s contribution increased from 33%to 40%in the interim,the number of infectious disease trials registered in India is low(325)compared to the number of oncology clinical trials(1936)[1].The number of phase 3 registrational antibacterial clinical trials conducted in India is also low(Table 1).This poses a serious public health challenge given the infectious disease burden in India[2].展开更多
In section‘Track decoding’of this article,one of the paragraphs was inadvertently missed out after the text'…shows the flow diagram of the Tr2-1121 track mode.'The missed paragraph is provided below.
摘要The management of severe tricuspid regurgitation(TR)in elderly patients has been transformed by transcatheter edge-to-edge repair(TEER),now a cornerstone for those at prohibitive surgical risk.[1]However,with increasing procedural volumes,recurrent TR after TEER is emerging as a relevant clinical challenge.[2]Although three-dimensional(3D)echocardiography provides superior characterization of complex post-procedural orifices,its role in guiding the difficult decision between redo intervention and conservative management in octogenarians remains insufficiently defined.[3,4]
摘要Since 2016,the number of clinical trials registered in the World Health Organization-International Clinical Trials Registry Platform has been steadily increasing.The number of clinical trials registered between 2018 and 2022 is 39765 for BRICS countries.Though India’s contribution increased from 33%to 40%in the interim,the number of infectious disease trials registered in India is low(325)compared to the number of oncology clinical trials(1936)[1].The number of phase 3 registrational antibacterial clinical trials conducted in India is also low(Table 1).This poses a serious public health challenge given the infectious disease burden in India[2].
摘要In section‘Track decoding’of this article,one of the paragraphs was inadvertently missed out after the text'…shows the flow diagram of the Tr2-1121 track mode.'The missed paragraph is provided below.