The convergence rate is one of the key performance measures for Nash equilibrium(NE)seeking strategies.In this work,we present several novel fast decoupled/coupled time-varying neurodynamic optimization approaches wit...The convergence rate is one of the key performance measures for Nash equilibrium(NE)seeking strategies.In this work,we present several novel fast decoupled/coupled time-varying neurodynamic optimization approaches with fixed-time(FT)convergence to Nash equilibrium seeking in non-cooperative games.The dynamics trajectories are demonstrated to converge to the NE solution within a fixed time from any initial states.The proposed neurodynamic networks exhibit a faster convergence rate with appropriately selected time-varying coefficients.Additionally,the upper bounds of the convergence time of the proposed NE seeking networks are smaller than those for strategies with constant coefficients.The robustness of the proposed NE seeking neurodynamic approaches under bounded perturbations is further studied.The efficacy and practicality of the proposed NE seeking approaches are validated through simulations and field-programmable gate array(FPGA)experiments on duopoly market games.展开更多
BACKGROUND Stromal vascular fraction(SVF)derived from adipose tissue(AT)is a heterogeneous cell mixture.SVF is commonly prepared via enzymatic digestion of AT.Typically,only the initial SVF(SVF1)is harvested,and the r...BACKGROUND Stromal vascular fraction(SVF)derived from adipose tissue(AT)is a heterogeneous cell mixture.SVF is commonly prepared via enzymatic digestion of AT.Typically,only the initial SVF(SVF1)is harvested,and the remaining AT is discarded.However,residual AT may contain viable regenerative cells.AIM To explore a novel approach involving a second enzymatic digestion to maximize stem cell yield,particularly relevant for pediatric patients or those with limited adipose reserves.METHODS AT samples obtained via liposuction were digested twice using collagenase type Ⅳ to yield SVF1 and SVF2(after 1st and 2nd digestions,respectively).Both fractions were assessed for cell viability,mononuclear cell count,plating efficiency,and the expression of surface markers via flow cytometry.Gene expression analysis of vascular endothelial growth factor,stromal cell-derived factor,nitric oxide synthase-3,CD14,matrix metalloproteinase 3,interleukin-4 receptor,P16,and P53 was performed using quantitative reverse transcription polymerase chain reaction.Histology was performed on AT samples to assess structural integrity and cellular composition across different digestion stages.RESULTS Results demonstrated that SVF2 contained a significant number of mononuclear cells and exhibited a high plating efficiency.Flow cytometry and gene expression analyses further confirmed that SVF2 retained regenerative cells.Furthermore,histological evaluation using hematoxylin and eosin staining revealed the presence of intact cells within the residual tissue post-first digestion.CONCLUSION In conclusion,secondary digestion of AT(typically discarded after 1st digestion),can yield additional regenerative cells.This method enhances stem cell number for stem cell-based therapies and is particularly valuable for pediatric patients and those with low-AT reserves.展开更多
In situ recycling is one of the most effective methods to dispose of earth pressure balance(EPB)shield waste muck with residual foaming agents with high moisture content.In this context,response surface methodology(RS...In situ recycling is one of the most effective methods to dispose of earth pressure balance(EPB)shield waste muck with residual foaming agents with high moisture content.In this context,response surface methodology(RSM)was employed to quantify the effects of independent variables,including flocculant dosage,defoamer dosage,and muck drying mass(MDM)and their interactions on defoaming-flocculation-dewatering indices.The polymeric aluminum chloride(PACL)and hydroxy silicone oil-glycerol polypropylene ether(H-G)were selected as the flocculant and defoamer.The contents of surfactants and foam stabilizers in residual foaming agents were determined using the proposed empirical equation.The defoaming ratio,antifoaming ratio,turbidity,moisture content,filtration loss ratio,and fall cone penetration depth were considered as dependent variables.The accuracy of developed RSM models was verified by the analysis results of variance,residuals,and paired t-test.Combined with the desirability approach,an optimal mixing ratio of 0.078 wt%PACL,0.016 wt%H-G,and 27.882 wt%MDM was recommended,leading to a defoaming ratio of 98.34 vol%for residual foams and a moisture content of 56.72 wt%for pressure-filtration cakes.Our findings were demonstrated to be able to provide useful guidance for prediction and optimization of the in situ recycling indicators of EPB shield waste muck in metro tunnel construction sites.展开更多
Dear Editor,In this letter,we focus on the algebraic relationship between the coefficient matrices and the solution of the stochastic algebraic Riccati equation.It is revealed that,if the coefficient matrices are in a...Dear Editor,In this letter,we focus on the algebraic relationship between the coefficient matrices and the solution of the stochastic algebraic Riccati equation.It is revealed that,if the coefficient matrices are in an algebra,then the solution(and also the control gain in many cases)is also in the same algebra.The main result is verified by a numerical simulation.展开更多
Dear Editor,Pose graph optimization(PGO)is a popular optimization approach that plays a crucial role in the simultaneous localization and mapping(SLAM)back-end.However,when incorrect loop closure constraints(referred ...Dear Editor,Pose graph optimization(PGO)is a popular optimization approach that plays a crucial role in the simultaneous localization and mapping(SLAM)back-end.However,when incorrect loop closure constraints(referred to as outliers)are present in the SLAM front-end,the standard PGO algorithm fails catastrophically and can not return an accurate map.To address this issue,this letter proposes a novel algorithm that leverages classical optimization methods to effectively handle outliers.The proposed algorithm introduces a new formulation that incorporates a credibility factor model,which improves the robustness of the optimization process.Additionally,an innovative consistency classification algorithm is developed to detect outliers.Extensive experiments are conducted on multiple benchmark datasets to evaluate the consistency and accuracy of the proposed algorithm.展开更多
A sequential statistical approach was applied to optimizing the fermentation medium of epothilones(Epos)production by means of a mutant which was obtained by treating polyangium cellulosum ATCC 15384 with nitrite and ...A sequential statistical approach was applied to optimizing the fermentation medium of epothilones(Epos)production by means of a mutant which was obtained by treating polyangium cellulosum ATCC 15384 with nitrite and ultraviolet.The effects of different carbon sources and nitrogen sources on the fermentation medium were tested,and the suitable ones were selected.Then a uniform design was employed to design the experiments.A linear model was developed for identifying the significant components in fermentation medium,while a third degree polynomial model was used for studying the relationship between the concentration of the components in fermentation medium and the yield of Epos(YEPs).A pattern search method was used for searching the optimum fermentation medium in the test space,which was as follows(g/L):potassium nitrate 8.00,soybean peptone 17.60,potassium hydrogen phos-phate 1.00,beef extraction 6.46,yeast extraction 1.00,calcium chloride 0.25,sodium chloride 1.00 and ferric chloride 0.02.The optimum fermentation medium was expected to result in a yield of Epos(YEPs)of 2.48 mg/L.The validation experiments with the optimum medium were performed in triplicate and the average yield of Epos was 2.45 mg/L which was 7.78 times higher than that of Epos prepared without optimization.展开更多
A comparison of arithmetic operations of two dynamic process optimization approaches called quasi-sequential approach and reduced Sequential Quadratic Programming(rSQP)simultaneous approach with respect to equality co...A comparison of arithmetic operations of two dynamic process optimization approaches called quasi-sequential approach and reduced Sequential Quadratic Programming(rSQP)simultaneous approach with respect to equality constrained optimization problems is presented.Through the detail comparison of arithmetic operations,it is concluded that the average iteration number within differential algebraic equations(DAEs)integration of quasi-sequential approach could be regarded as a criterion.One formula is given to calculate the threshold value of average iteration number.If the average iteration number is less than the threshold value,quasi-sequential approach takes advantage of rSQP simultaneous approach which is more suitable contrarily.Two optimal control problems are given to demonstrate the usage of threshold value.For optimal control problems whose objective is to stay near desired operating point,the iteration number is usually small.Therefore,quasi-sequential approach seems more suitable for such problems.展开更多
Rechargeable magnesium-ion batteries(MIBs) are favorable substitutes for conventional lithium-ion batteries(LIBs) because of abundant magnesium reserves, a high theoretical energy density, and great inherent safety. O...Rechargeable magnesium-ion batteries(MIBs) are favorable substitutes for conventional lithium-ion batteries(LIBs) because of abundant magnesium reserves, a high theoretical energy density, and great inherent safety. Organic electrode materials with excellent structural tunability,unique coordination reaction mechanisms, and environmental friendliness offer great potential to promote the electrochemical performance of MIBs. However, research on organic magnesium battery cathode materials is still preliminary with many significant challenges to be resolved including low electrical conductivity and unwanted but severe dissolution in useful electrolytes. Herein, we provide a detailed overview of reported organic cathode materials for MIBs. We begin with basic properties such as charge storage mechanisms(e.g., n-, p-, and bipolartype), moving to recent advances in various types of organic cathodes including carbonyl-, nitrogen-, and sulfur-based materials. To shed light on the diverse strategies targeting high-performance Mg-organic batteries, elaborate summaries of various approaches are presented.Generally, these strategies include molecular design, polymerization, mixing with carbon, nanosizing and electrolyte/separator optimization.This review provides insights on exploring high-performance organic cathodes in rechargeable MIBs.展开更多
We present a new aerodynamic design method based on the lattice Boltzmann method (LBM) and the adjoint approach. The flow field and the adjoint equation are numerically simulated by the GILBM (generalized form of i...We present a new aerodynamic design method based on the lattice Boltzmann method (LBM) and the adjoint approach. The flow field and the adjoint equation are numerically simulated by the GILBM (generalized form of interpolation supplemented LBM) on non-uniform meshes. The first-order approximation for the equilibrium dis- tribution function on the boundary is proposed to diminish the singularity of boundary conditions. Further, a new treatment of the solid boundary in the LBM is described par- ticularly for the airfoil optimization design problem. For a given objective function, the adjoint equation and its boundary conditions are derived analytically. The feasibility and accuracy of the new approach have been perfectly validated by the design optimization of NACA0012 airfoil.展开更多
In the present paper,a so-called epsilon-continuation approach is proposed for the solution of singular optimum in truss topology optimization problems.This approach is an improved version of the epsilon-relaxed appro...In the present paper,a so-called epsilon-continuation approach is proposed for the solution of singular optimum in truss topology optimization problems.This approach is an improved version of the epsilon-relaxed approach developed by the authors previously.In the proposed approach, we start the optimization process from a relaxation parameter with a relatively large value and obtain a solution by applying the epsilon-relaxed approach.Then we decrease the value of the relaxation parameter by a small amount and choose the optimal solution found from the previous optimization process as the initial design for the next optimization.This continuation process is continued until a small termination value of the relaxation parameter is reached.Convergence analysis of the proposed approach is also presented.Numerical examples show that this approach can alleviate the dependence of the final solution on the initial choice of the design variable and enhance the probability of finding the singular optimum from rather arbitrary initial designs.展开更多
Realizing optimal control performance for continuum robots(CRs) poses huge challenges on traditional modelbased optimal control approaches due to their high degrees of freedom,complex nonlinear dynamics and soft conti...Realizing optimal control performance for continuum robots(CRs) poses huge challenges on traditional modelbased optimal control approaches due to their high degrees of freedom,complex nonlinear dynamics and soft continuum morphologies which are difficult to explicitly model.This paper proposes a model-free adaptive optimal control algorithm(ADAPT)for CRs.In our strategy,we consider CRs as a class of nonlinear continuous-time dynamical systems in the state space,wherein the position of the end-effector is considered as the state and the input torque is mapped as the control input.Then,the optimized Hamilton-Jacobi-Bellman(HJB) equation is derived by optimal control principles,and subsequently solved by the proposed ADAPT algorithm without requiring knowledge of the original system dynamics.Under some mild assumptions,the global stability and convergence of the closed-loop control approach are guaranteed.Several simulation experiments are conducted on a magnetic CR(MCR) to demonstrate the practicality and effectiveness of the ADAPT algorithm.展开更多
With the rapid development of intelligent navigation technology,efficient and safe path planning for mobile robots has become a core requirement.To address the challenges of complex dynamic environments,this paper pro...With the rapid development of intelligent navigation technology,efficient and safe path planning for mobile robots has become a core requirement.To address the challenges of complex dynamic environments,this paper proposes an intelligent path planning framework based on grid map modeling.First,an improved Safe and Smooth A*(SSA*)algorithm is employed for global path planning.By incorporating obstacle expansion and cornerpoint optimization,the proposed SSA*enhances the safety and smoothness of the planned path.Then,a Partitioned Dynamic Window Approach(PDWA)is integrated for local planning,which is triggered when dynamic or sudden static obstacles appear,enabling real-time obstacle avoidance and path adjustment.A unified objective function is constructed,considering path length,safety,and smoothness comprehensively.Multiple simulation experiments are conducted on typical port grid maps.The results demonstrate that the improved SSA*significantly reduces the number of expanded nodes and computation time in static environmentswhile generating smoother and safer paths.Meanwhile,the PDWA exhibits strong real-time performance and robustness in dynamic scenarios,achieving shorter paths and lower planning times compared to other graph search algorithms.The proposedmethodmaintains stable performance across maps of different scales and various port scenarios,verifying its practicality and potential for wider application.展开更多
The minimum vertex cover problem(MVCP)is a well-known combinatorial optimization problem of graph theory.The MVCP is an NP(nondeterministic polynomial)complete problem and it has an exponential growing complexity with...The minimum vertex cover problem(MVCP)is a well-known combinatorial optimization problem of graph theory.The MVCP is an NP(nondeterministic polynomial)complete problem and it has an exponential growing complexity with respect to the size of a graph.No algorithm exits till date that can exactly solve the problem in a deterministic polynomial time scale.However,several algorithms are proposed that solve the problem approximately in a short polynomial time scale.Such algorithms are useful for large size graphs,for which exact solution of MVCP is impossible with current computational resources.The MVCP has a wide range of applications in the fields like bioinformatics,biochemistry,circuit design,electrical engineering,data aggregation,networking,internet traffic monitoring,pattern recognition,marketing and franchising etc.This work aims to solve the MVCP approximately by a novel graph decomposition approach.The decomposition of the graph yields a subgraph that contains edges shared by triangular edge structures.A subgraph is covered to yield a subgraph that forms one or more Hamiltonian cycles or paths.In order to reduce complexity of the algorithm a new strategy is also proposed.The reduction strategy can be used for any algorithm solving MVCP.Based on the graph decomposition and the reduction strategy,two algorithms are formulated to approximately solve the MVCP.These algorithms are tested using well known standard benchmark graphs.The key feature of the results is a good approximate error ratio and improvement in optimum vertex cover values for few graphs.展开更多
Biodiesel is an alternative renewable fuel which is produced by using biomass resources. Its physicochemical properties are close to those of the petroleum diesel fuel. This study highlights biodiesel production from ...Biodiesel is an alternative renewable fuel which is produced by using biomass resources. Its physicochemical properties are close to those of the petroleum diesel fuel. This study highlights biodiesel production from safflower seed oil. The main aim of this experimental work is to optimize the process parameters, namely the methanolto-oil molar ratio, catalyst concentration, reaction time and reaction temperature for biodiesel production. The Taguchi robust design approach was used with an L9 orthogonal array to analyze the influence of process factors on performance parameters. The results showed that the optimum yield of biodiesel was 93.8% with viscosity 5.60 c St, with a methanol-to-oil molar ratio of 4:1, catalyst concentration of 1.5 wt%, reaction time of 90 min and reaction temperature of 60 ℃. The catalyst concentration was found to be the most influencing parameter which contributed 51.1% and 50.8% of the total effect on the yield of biodiesel, Y;, and viscosity of biodiesel, Y;, respectively.展开更多
In view of the fact that the follow-up search for an optimal topology is affected by deleting a large number of high-relative-density elements. When the typical density interpolation approach, namely, solid isotropic ...In view of the fact that the follow-up search for an optimal topology is affected by deleting a large number of high-relative-density elements. When the typical density interpolation approach, namely, solid isotropic microstructures with penalization (SIMP), is employed in the continuum structural topology optimization, a new density interpolation approach based on the logistic function is proposed in this paper. This method can weaken low-relative-density elements while enhancing high-relative-density elements by polarization, and then rationally realize polarization of the intermediate density elements. It can reduce the number of gray-scale elements as much as possible to get the optimal topology with distinct boundaries in conjunction with the sensitivity filtering method based on particle swarm optimization (PSO). Several typical numerical examples are given to demonstrate this method.展开更多
The Nesterov accelerated dynamical approach serves as an essential tool for addressing convex optimization problems with accelerated convergence rates.Most previous studies in this field have primarily concentrated on...The Nesterov accelerated dynamical approach serves as an essential tool for addressing convex optimization problems with accelerated convergence rates.Most previous studies in this field have primarily concentrated on unconstrained smooth con-vex optimization problems.In this paper,on the basis of primal-dual dynamical approach,Nesterov accelerated dynamical approach,projection operator and directional gradient,we present two accelerated primal-dual projection neurodynamic approaches with time scaling to address convex optimization problems with smooth and nonsmooth objective functions subject to linear and set constraints,which consist of a second-order ODE(ordinary differential equation)or differential conclusion system for the primal variables and a first-order ODE for the dual vari-ables.By satisfying specific conditions for time scaling,we demonstrate that the proposed approaches have a faster conver-gence rate.This only requires assuming convexity of the objective function.We validate the effectiveness of our proposed two accel-erated primal-dual projection neurodynamic approaches through numerical experiments.展开更多
In recent decades,fog computing has played a vital role in executing parallel computational tasks,specifically,scientific workflow tasks.In cloud data centers,fog computing takes more time to run workflow applications...In recent decades,fog computing has played a vital role in executing parallel computational tasks,specifically,scientific workflow tasks.In cloud data centers,fog computing takes more time to run workflow applications.Therefore,it is essential to develop effective models for Virtual Machine(VM)allocation and task scheduling in fog computing environments.Effective task scheduling,VM migration,and allocation,altogether optimize the use of computational resources across different fog nodes.This process ensures that the tasks are executed with minimal energy consumption,which reduces the chances of resource bottlenecks.In this manuscript,the proposed framework comprises two phases:(i)effective task scheduling using a fractional selectivity approach and(ii)VM allocation by proposing an algorithm by the name of Fitness Sharing Chaotic Particle Swarm Optimization(FSCPSO).The proposed FSCPSO algorithm integrates the concepts of chaos theory and fitness sharing that effectively balance both global exploration and local exploitation.This balance enables the use of a wide range of solutions that leads to minimal total cost and makespan,in comparison to other traditional optimization algorithms.The FSCPSO algorithm’s performance is analyzed using six evaluation measures namely,Load Balancing Level(LBL),Average Resource Utilization(ARU),total cost,makespan,energy consumption,and response time.In relation to the conventional optimization algorithms,the FSCPSO algorithm achieves a higher LBL of 39.12%,ARU of 58.15%,a minimal total cost of 1175,and a makespan of 85.87 ms,particularly when evaluated for 50 tasks.展开更多
The majority of topology optimization of compliant mechanisms uses linear finite element models to find the structure responses.Because the displacements of compliant mechanisms are intrinsically large,the topological...The majority of topology optimization of compliant mechanisms uses linear finite element models to find the structure responses.Because the displacements of compliant mechanisms are intrinsically large,the topological design can not provide quantitatively accurate result.Thus,topological design of these mechanisms considering geometrical nonlinearities is essential.A new methodology for geometrical nonlinear topology optimization of compliant mechanisms under displacement loading is presented.Frame elements are chosen to represent the design domain because they are capable of capturing the bending modes.Geometrically nonlinear structural response is obtained by using the co-rotational total Lagrange finite element formulation,and the equilibrium is solved by using the incremental scheme combined with Newton-Raphson iteration.The multi-objective function is developed by the minimum strain energy and maximum geometric advantage to design the mechanism which meets both stiffness and flexibility requirements,respectively.The adjoint method and the direct differentiation method are applied to obtain the sensitivities of the objective functions.The method of moving asymptotes(MMA)is employed as optimizer.The numerical example is simulated to show that the optimal mechanism based on geometrically nonlinear formulation not only has more flexibility and stiffness than that based on linear formulation,but also has better stress distribution than the one.It is necessary to design compliant mechanisms using geometrically nonlinear topology optimization.Compared with linear formulation,the formulation for geometrically nonlinear topology optimization of compliant mechanisms can give the compliant mechanism that has better mechanical performance.A new method is provided for topological design of large displacement compliant mechanisms.展开更多
In this article, a novel scalarization technique, called the improved objective-constraint approach, is introduced to find efficient solutions of a given multiobjective programming problem. The presented scalarized pr...In this article, a novel scalarization technique, called the improved objective-constraint approach, is introduced to find efficient solutions of a given multiobjective programming problem. The presented scalarized problem extends the objective-constraint problem. It is demonstrated that how adding variables to the scalarized problem, can lead to find conditions for (weakly, properly) Pareto optimal solutions. Applying the obtained necessary and sufficient conditions, two algorithms for generating the Pareto front approximation of bi-objective and three-objective programming problems are designed. These algorithms are easy to implement and can achieve an even approximation of (weakly, properly) Pareto optimal solutions. These algorithms can be generalized for optimization problems with more than three criterion functions, too. The effectiveness and capability of the algorithms are demonstrated in test problems.展开更多
In the Acoustics channel,it is incredibly challenging to offer data transfer for time-sourced applications in an energy-efficient manner due to higher error rate and propagation delay.Subsequently,conventional re-tran...In the Acoustics channel,it is incredibly challenging to offer data transfer for time-sourced applications in an energy-efficient manner due to higher error rate and propagation delay.Subsequently,conventional re-transmission over any failure generally initiates significantly larger end-to-end delay,and therefore it is not probable for time-based services.Moreover,standard techniques without any re-transmission consume enormous energy.This investigation proposes a novel multi-hop energy-aware transmission-based intelligent water wave optimization strategy.It ensures reduced end-to-end while attaining potential amongst overall energy efficiency end-to-end packet delay.It merges a naturally inspired meta-heuristic approach with multi-hop routing for data packets to reach the destination.The appropriate design of this Meta heuristic-based energy-aware scheme consumes lesser energy than the conventional one-hop transmission strategy without re-transmission.However,there is no hop-by-hop re-transmission facilitated.The proposed model shows only lesser delay than conventional methods with re-transmission.This work facilitates extensive work to carry out the proposed model performance with the MATLAB simulation environment.The results illustrate that the model is exceptionally energyefficient with lesser packet delays.With 500 nodes,the packet delivery ratio of proposed model is 100%,average delay is reduced by 2%,total energy consumption is 8 J,average packet redundancy is 1.856,and idle energy is 6.9Mwh.The proposed model outperforms existing approaches like OSF,AOR,and DMR respectively.展开更多
基金supported in part by the National Natural Science Foundation of China(62403336,62373262,62373310)the Research Grants Council of Hong Kong(CityU-11208223,CityU-11213023,CityU-11205724)+2 种基金the China Postdoctoral Science Foundation(2023M742457)the Postdoctoral Fellowship Program(Grade B)of China Postdoctoral Science Foundation(GZB20230467)the Foundation of Key Laboratory of System Control and Information Processing of Ministry of Education of China(Scip20240107)。
摘要The convergence rate is one of the key performance measures for Nash equilibrium(NE)seeking strategies.In this work,we present several novel fast decoupled/coupled time-varying neurodynamic optimization approaches with fixed-time(FT)convergence to Nash equilibrium seeking in non-cooperative games.The dynamics trajectories are demonstrated to converge to the NE solution within a fixed time from any initial states.The proposed neurodynamic networks exhibit a faster convergence rate with appropriately selected time-varying coefficients.Additionally,the upper bounds of the convergence time of the proposed NE seeking networks are smaller than those for strategies with constant coefficients.The robustness of the proposed NE seeking neurodynamic approaches under bounded perturbations is further studied.The efficacy and practicality of the proposed NE seeking approaches are validated through simulations and field-programmable gate array(FPGA)experiments on duopoly market games.
基金supported by a grant from the Higher Education Commission of Pakistan.
摘要BACKGROUND Stromal vascular fraction(SVF)derived from adipose tissue(AT)is a heterogeneous cell mixture.SVF is commonly prepared via enzymatic digestion of AT.Typically,only the initial SVF(SVF1)is harvested,and the remaining AT is discarded.However,residual AT may contain viable regenerative cells.AIM To explore a novel approach involving a second enzymatic digestion to maximize stem cell yield,particularly relevant for pediatric patients or those with limited adipose reserves.METHODS AT samples obtained via liposuction were digested twice using collagenase type Ⅳ to yield SVF1 and SVF2(after 1st and 2nd digestions,respectively).Both fractions were assessed for cell viability,mononuclear cell count,plating efficiency,and the expression of surface markers via flow cytometry.Gene expression analysis of vascular endothelial growth factor,stromal cell-derived factor,nitric oxide synthase-3,CD14,matrix metalloproteinase 3,interleukin-4 receptor,P16,and P53 was performed using quantitative reverse transcription polymerase chain reaction.Histology was performed on AT samples to assess structural integrity and cellular composition across different digestion stages.RESULTS Results demonstrated that SVF2 contained a significant number of mononuclear cells and exhibited a high plating efficiency.Flow cytometry and gene expression analyses further confirmed that SVF2 retained regenerative cells.Furthermore,histological evaluation using hematoxylin and eosin staining revealed the presence of intact cells within the residual tissue post-first digestion.CONCLUSION In conclusion,secondary digestion of AT(typically discarded after 1st digestion),can yield additional regenerative cells.This method enhances stem cell number for stem cell-based therapies and is particularly valuable for pediatric patients and those with low-AT reserves.
基金supported by the National Youth Top-notch Talent Support Program of China(Grant No.00389335)the National Natural Science Foundation of China(Grant No.52378392)the“Foal Eagle Program”Youth Top-notch Talent Project of Fujian Province(Grant No.00387088).
摘要In situ recycling is one of the most effective methods to dispose of earth pressure balance(EPB)shield waste muck with residual foaming agents with high moisture content.In this context,response surface methodology(RSM)was employed to quantify the effects of independent variables,including flocculant dosage,defoamer dosage,and muck drying mass(MDM)and their interactions on defoaming-flocculation-dewatering indices.The polymeric aluminum chloride(PACL)and hydroxy silicone oil-glycerol polypropylene ether(H-G)were selected as the flocculant and defoamer.The contents of surfactants and foam stabilizers in residual foaming agents were determined using the proposed empirical equation.The defoaming ratio,antifoaming ratio,turbidity,moisture content,filtration loss ratio,and fall cone penetration depth were considered as dependent variables.The accuracy of developed RSM models was verified by the analysis results of variance,residuals,and paired t-test.Combined with the desirability approach,an optimal mixing ratio of 0.078 wt%PACL,0.016 wt%H-G,and 27.882 wt%MDM was recommended,leading to a defoaming ratio of 98.34 vol%for residual foams and a moisture content of 56.72 wt%for pressure-filtration cakes.Our findings were demonstrated to be able to provide useful guidance for prediction and optimization of the in situ recycling indicators of EPB shield waste muck in metro tunnel construction sites.
摘要Dear Editor,In this letter,we focus on the algebraic relationship between the coefficient matrices and the solution of the stochastic algebraic Riccati equation.It is revealed that,if the coefficient matrices are in an algebra,then the solution(and also the control gain in many cases)is also in the same algebra.The main result is verified by a numerical simulation.
基金supported in part by the National Nature Science Foundation of China(62273239,62103283).
摘要Dear Editor,Pose graph optimization(PGO)is a popular optimization approach that plays a crucial role in the simultaneous localization and mapping(SLAM)back-end.However,when incorrect loop closure constraints(referred to as outliers)are present in the SLAM front-end,the standard PGO algorithm fails catastrophically and can not return an accurate map.To address this issue,this letter proposes a novel algorithm that leverages classical optimization methods to effectively handle outliers.The proposed algorithm introduces a new formulation that incorporates a credibility factor model,which improves the robustness of the optimization process.Additionally,an innovative consistency classification algorithm is developed to detect outliers.Extensive experiments are conducted on multiple benchmark datasets to evaluate the consistency and accuracy of the proposed algorithm.
基金Supported by the Science Technology Development Project of Jilin Province,China(No.20020503-2)
摘要A sequential statistical approach was applied to optimizing the fermentation medium of epothilones(Epos)production by means of a mutant which was obtained by treating polyangium cellulosum ATCC 15384 with nitrite and ultraviolet.The effects of different carbon sources and nitrogen sources on the fermentation medium were tested,and the suitable ones were selected.Then a uniform design was employed to design the experiments.A linear model was developed for identifying the significant components in fermentation medium,while a third degree polynomial model was used for studying the relationship between the concentration of the components in fermentation medium and the yield of Epos(YEPs).A pattern search method was used for searching the optimum fermentation medium in the test space,which was as follows(g/L):potassium nitrate 8.00,soybean peptone 17.60,potassium hydrogen phos-phate 1.00,beef extraction 6.46,yeast extraction 1.00,calcium chloride 0.25,sodium chloride 1.00 and ferric chloride 0.02.The optimum fermentation medium was expected to result in a yield of Epos(YEPs)of 2.48 mg/L.The validation experiments with the optimum medium were performed in triplicate and the average yield of Epos was 2.45 mg/L which was 7.78 times higher than that of Epos prepared without optimization.
基金Supported by the National Natural Science Foundation of China(20676117) the National Creative Research Groups Science Foundation of China(60421002)
摘要A comparison of arithmetic operations of two dynamic process optimization approaches called quasi-sequential approach and reduced Sequential Quadratic Programming(rSQP)simultaneous approach with respect to equality constrained optimization problems is presented.Through the detail comparison of arithmetic operations,it is concluded that the average iteration number within differential algebraic equations(DAEs)integration of quasi-sequential approach could be regarded as a criterion.One formula is given to calculate the threshold value of average iteration number.If the average iteration number is less than the threshold value,quasi-sequential approach takes advantage of rSQP simultaneous approach which is more suitable contrarily.Two optimal control problems are given to demonstrate the usage of threshold value.For optimal control problems whose objective is to stay near desired operating point,the iteration number is usually small.Therefore,quasi-sequential approach seems more suitable for such problems.
基金the support from the National Key Research & Development Program (2022YFB3803700) of ChinaNational Natural Science Foundation (No.52171186)the support from the Center of Hydrogen Science,Shanghai Jiao Tong University。
摘要Rechargeable magnesium-ion batteries(MIBs) are favorable substitutes for conventional lithium-ion batteries(LIBs) because of abundant magnesium reserves, a high theoretical energy density, and great inherent safety. Organic electrode materials with excellent structural tunability,unique coordination reaction mechanisms, and environmental friendliness offer great potential to promote the electrochemical performance of MIBs. However, research on organic magnesium battery cathode materials is still preliminary with many significant challenges to be resolved including low electrical conductivity and unwanted but severe dissolution in useful electrolytes. Herein, we provide a detailed overview of reported organic cathode materials for MIBs. We begin with basic properties such as charge storage mechanisms(e.g., n-, p-, and bipolartype), moving to recent advances in various types of organic cathodes including carbonyl-, nitrogen-, and sulfur-based materials. To shed light on the diverse strategies targeting high-performance Mg-organic batteries, elaborate summaries of various approaches are presented.Generally, these strategies include molecular design, polymerization, mixing with carbon, nanosizing and electrolyte/separator optimization.This review provides insights on exploring high-performance organic cathodes in rechargeable MIBs.
基金Project supported by the National Basic Research Program of China(No.2014CB744100)the National Natural Science Foundation of China(Nos.61403245 and 91648119)the Shanghai Municipal Science and Technology Commision(No.14500500400)
摘要We present a new aerodynamic design method based on the lattice Boltzmann method (LBM) and the adjoint approach. The flow field and the adjoint equation are numerically simulated by the GILBM (generalized form of interpolation supplemented LBM) on non-uniform meshes. The first-order approximation for the equilibrium dis- tribution function on the boundary is proposed to diminish the singularity of boundary conditions. Further, a new treatment of the solid boundary in the LBM is described par- ticularly for the airfoil optimization design problem. For a given objective function, the adjoint equation and its boundary conditions are derived analytically. The feasibility and accuracy of the new approach have been perfectly validated by the design optimization of NACA0012 airfoil.
基金The project supported by the National Natural Science Foundation of China (10102003,10032010 and 10032030)
摘要In the present paper,a so-called epsilon-continuation approach is proposed for the solution of singular optimum in truss topology optimization problems.This approach is an improved version of the epsilon-relaxed approach developed by the authors previously.In the proposed approach, we start the optimization process from a relaxation parameter with a relatively large value and obtain a solution by applying the epsilon-relaxed approach.Then we decrease the value of the relaxation parameter by a small amount and choose the optimal solution found from the previous optimization process as the initial design for the next optimization.This continuation process is continued until a small termination value of the relaxation parameter is reached.Convergence analysis of the proposed approach is also presented.Numerical examples show that this approach can alleviate the dependence of the final solution on the initial choice of the design variable and enhance the probability of finding the singular optimum from rather arbitrary initial designs.
基金supported in part by the Innovation and Technology Commission of Hong Kong,China(ITS/136/20,ITS/234/21,MHP/096/22,ITS/235/22)Multi-Scale Medical Robotics Center,InnoHK,China(8312051)+1 种基金Research Grants Council(RGC) of Hong Kong,China(CUHK 14217822,CUHK14207823,AoE/E-407/24-N)The Chinese University of Hong Kong(CUHK) Direct Grant。
摘要Realizing optimal control performance for continuum robots(CRs) poses huge challenges on traditional modelbased optimal control approaches due to their high degrees of freedom,complex nonlinear dynamics and soft continuum morphologies which are difficult to explicitly model.This paper proposes a model-free adaptive optimal control algorithm(ADAPT)for CRs.In our strategy,we consider CRs as a class of nonlinear continuous-time dynamical systems in the state space,wherein the position of the end-effector is considered as the state and the input torque is mapped as the control input.Then,the optimized Hamilton-Jacobi-Bellman(HJB) equation is derived by optimal control principles,and subsequently solved by the proposed ADAPT algorithm without requiring knowledge of the original system dynamics.Under some mild assumptions,the global stability and convergence of the closed-loop control approach are guaranteed.Several simulation experiments are conducted on a magnetic CR(MCR) to demonstrate the practicality and effectiveness of the ADAPT algorithm.
摘要With the rapid development of intelligent navigation technology,efficient and safe path planning for mobile robots has become a core requirement.To address the challenges of complex dynamic environments,this paper proposes an intelligent path planning framework based on grid map modeling.First,an improved Safe and Smooth A*(SSA*)algorithm is employed for global path planning.By incorporating obstacle expansion and cornerpoint optimization,the proposed SSA*enhances the safety and smoothness of the planned path.Then,a Partitioned Dynamic Window Approach(PDWA)is integrated for local planning,which is triggered when dynamic or sudden static obstacles appear,enabling real-time obstacle avoidance and path adjustment.A unified objective function is constructed,considering path length,safety,and smoothness comprehensively.Multiple simulation experiments are conducted on typical port grid maps.The results demonstrate that the improved SSA*significantly reduces the number of expanded nodes and computation time in static environmentswhile generating smoother and safer paths.Meanwhile,the PDWA exhibits strong real-time performance and robustness in dynamic scenarios,achieving shorter paths and lower planning times compared to other graph search algorithms.The proposedmethodmaintains stable performance across maps of different scales and various port scenarios,verifying its practicality and potential for wider application.
摘要The minimum vertex cover problem(MVCP)is a well-known combinatorial optimization problem of graph theory.The MVCP is an NP(nondeterministic polynomial)complete problem and it has an exponential growing complexity with respect to the size of a graph.No algorithm exits till date that can exactly solve the problem in a deterministic polynomial time scale.However,several algorithms are proposed that solve the problem approximately in a short polynomial time scale.Such algorithms are useful for large size graphs,for which exact solution of MVCP is impossible with current computational resources.The MVCP has a wide range of applications in the fields like bioinformatics,biochemistry,circuit design,electrical engineering,data aggregation,networking,internet traffic monitoring,pattern recognition,marketing and franchising etc.This work aims to solve the MVCP approximately by a novel graph decomposition approach.The decomposition of the graph yields a subgraph that contains edges shared by triangular edge structures.A subgraph is covered to yield a subgraph that forms one or more Hamiltonian cycles or paths.In order to reduce complexity of the algorithm a new strategy is also proposed.The reduction strategy can be used for any algorithm solving MVCP.Based on the graph decomposition and the reduction strategy,two algorithms are formulated to approximately solve the MVCP.These algorithms are tested using well known standard benchmark graphs.The key feature of the results is a good approximate error ratio and improvement in optimum vertex cover values for few graphs.
摘要Biodiesel is an alternative renewable fuel which is produced by using biomass resources. Its physicochemical properties are close to those of the petroleum diesel fuel. This study highlights biodiesel production from safflower seed oil. The main aim of this experimental work is to optimize the process parameters, namely the methanolto-oil molar ratio, catalyst concentration, reaction time and reaction temperature for biodiesel production. The Taguchi robust design approach was used with an L9 orthogonal array to analyze the influence of process factors on performance parameters. The results showed that the optimum yield of biodiesel was 93.8% with viscosity 5.60 c St, with a methanol-to-oil molar ratio of 4:1, catalyst concentration of 1.5 wt%, reaction time of 90 min and reaction temperature of 60 ℃. The catalyst concentration was found to be the most influencing parameter which contributed 51.1% and 50.8% of the total effect on the yield of biodiesel, Y;, and viscosity of biodiesel, Y;, respectively.
基金supported by the National Natural Science Foundation of China(No.51105229)the National Science Foundation for Distinguished Young Scholars of Hubei Province of China(No.2013CFA022)+1 种基金the Science and Technology Support Program of Hubei Province of China(N0.2015BHE026)the Fund Project of Outstanding Dissertation of China Three Gorges University(No.2014PY026)
摘要In view of the fact that the follow-up search for an optimal topology is affected by deleting a large number of high-relative-density elements. When the typical density interpolation approach, namely, solid isotropic microstructures with penalization (SIMP), is employed in the continuum structural topology optimization, a new density interpolation approach based on the logistic function is proposed in this paper. This method can weaken low-relative-density elements while enhancing high-relative-density elements by polarization, and then rationally realize polarization of the intermediate density elements. It can reduce the number of gray-scale elements as much as possible to get the optimal topology with distinct boundaries in conjunction with the sensitivity filtering method based on particle swarm optimization (PSO). Several typical numerical examples are given to demonstrate this method.
基金supported by the National Natural Science Foundation of China(62176218,62176027)the Fundamental Research Funds for the Central Universities(XDJK2020TY003)the Funds for Chongqing Talent Plan(cstc2024ycjh-bgzxm0082)。
摘要The Nesterov accelerated dynamical approach serves as an essential tool for addressing convex optimization problems with accelerated convergence rates.Most previous studies in this field have primarily concentrated on unconstrained smooth con-vex optimization problems.In this paper,on the basis of primal-dual dynamical approach,Nesterov accelerated dynamical approach,projection operator and directional gradient,we present two accelerated primal-dual projection neurodynamic approaches with time scaling to address convex optimization problems with smooth and nonsmooth objective functions subject to linear and set constraints,which consist of a second-order ODE(ordinary differential equation)or differential conclusion system for the primal variables and a first-order ODE for the dual vari-ables.By satisfying specific conditions for time scaling,we demonstrate that the proposed approaches have a faster conver-gence rate.This only requires assuming convexity of the objective function.We validate the effectiveness of our proposed two accel-erated primal-dual projection neurodynamic approaches through numerical experiments.
基金This work was supported in part by the National Science and Technology Council of Taiwan,under Contract NSTC 112-2410-H-324-001-MY2.
摘要In recent decades,fog computing has played a vital role in executing parallel computational tasks,specifically,scientific workflow tasks.In cloud data centers,fog computing takes more time to run workflow applications.Therefore,it is essential to develop effective models for Virtual Machine(VM)allocation and task scheduling in fog computing environments.Effective task scheduling,VM migration,and allocation,altogether optimize the use of computational resources across different fog nodes.This process ensures that the tasks are executed with minimal energy consumption,which reduces the chances of resource bottlenecks.In this manuscript,the proposed framework comprises two phases:(i)effective task scheduling using a fractional selectivity approach and(ii)VM allocation by proposing an algorithm by the name of Fitness Sharing Chaotic Particle Swarm Optimization(FSCPSO).The proposed FSCPSO algorithm integrates the concepts of chaos theory and fitness sharing that effectively balance both global exploration and local exploitation.This balance enables the use of a wide range of solutions that leads to minimal total cost and makespan,in comparison to other traditional optimization algorithms.The FSCPSO algorithm’s performance is analyzed using six evaluation measures namely,Load Balancing Level(LBL),Average Resource Utilization(ARU),total cost,makespan,energy consumption,and response time.In relation to the conventional optimization algorithms,the FSCPSO algorithm achieves a higher LBL of 39.12%,ARU of 58.15%,a minimal total cost of 1175,and a makespan of 85.87 ms,particularly when evaluated for 50 tasks.
基金supported by National Science Foundation for Distinguished Young Scholars of China(Grant No.50825504)National Natural Science Foundation of China(Grant No.50775073)United Fund of Natural Science Foundation of China and Guangdong Province(Grant No.U0934004)
摘要The majority of topology optimization of compliant mechanisms uses linear finite element models to find the structure responses.Because the displacements of compliant mechanisms are intrinsically large,the topological design can not provide quantitatively accurate result.Thus,topological design of these mechanisms considering geometrical nonlinearities is essential.A new methodology for geometrical nonlinear topology optimization of compliant mechanisms under displacement loading is presented.Frame elements are chosen to represent the design domain because they are capable of capturing the bending modes.Geometrically nonlinear structural response is obtained by using the co-rotational total Lagrange finite element formulation,and the equilibrium is solved by using the incremental scheme combined with Newton-Raphson iteration.The multi-objective function is developed by the minimum strain energy and maximum geometric advantage to design the mechanism which meets both stiffness and flexibility requirements,respectively.The adjoint method and the direct differentiation method are applied to obtain the sensitivities of the objective functions.The method of moving asymptotes(MMA)is employed as optimizer.The numerical example is simulated to show that the optimal mechanism based on geometrically nonlinear formulation not only has more flexibility and stiffness than that based on linear formulation,but also has better stress distribution than the one.It is necessary to design compliant mechanisms using geometrically nonlinear topology optimization.Compared with linear formulation,the formulation for geometrically nonlinear topology optimization of compliant mechanisms can give the compliant mechanism that has better mechanical performance.A new method is provided for topological design of large displacement compliant mechanisms.
摘要In this article, a novel scalarization technique, called the improved objective-constraint approach, is introduced to find efficient solutions of a given multiobjective programming problem. The presented scalarized problem extends the objective-constraint problem. It is demonstrated that how adding variables to the scalarized problem, can lead to find conditions for (weakly, properly) Pareto optimal solutions. Applying the obtained necessary and sufficient conditions, two algorithms for generating the Pareto front approximation of bi-objective and three-objective programming problems are designed. These algorithms are easy to implement and can achieve an even approximation of (weakly, properly) Pareto optimal solutions. These algorithms can be generalized for optimization problems with more than three criterion functions, too. The effectiveness and capability of the algorithms are demonstrated in test problems.
摘要In the Acoustics channel,it is incredibly challenging to offer data transfer for time-sourced applications in an energy-efficient manner due to higher error rate and propagation delay.Subsequently,conventional re-transmission over any failure generally initiates significantly larger end-to-end delay,and therefore it is not probable for time-based services.Moreover,standard techniques without any re-transmission consume enormous energy.This investigation proposes a novel multi-hop energy-aware transmission-based intelligent water wave optimization strategy.It ensures reduced end-to-end while attaining potential amongst overall energy efficiency end-to-end packet delay.It merges a naturally inspired meta-heuristic approach with multi-hop routing for data packets to reach the destination.The appropriate design of this Meta heuristic-based energy-aware scheme consumes lesser energy than the conventional one-hop transmission strategy without re-transmission.However,there is no hop-by-hop re-transmission facilitated.The proposed model shows only lesser delay than conventional methods with re-transmission.This work facilitates extensive work to carry out the proposed model performance with the MATLAB simulation environment.The results illustrate that the model is exceptionally energyefficient with lesser packet delays.With 500 nodes,the packet delivery ratio of proposed model is 100%,average delay is reduced by 2%,total energy consumption is 8 J,average packet redundancy is 1.856,and idle energy is 6.9Mwh.The proposed model outperforms existing approaches like OSF,AOR,and DMR respectively.