BACKGROUND Benign prostatic hyperplasia(BPH)-that’s BPH,by the way-is a pretty serious problem for older guys when it comes to their bladders.Surgery is the primary treatment for patients with moderate-to-severe symp...BACKGROUND Benign prostatic hyperplasia(BPH)-that’s BPH,by the way-is a pretty serious problem for older guys when it comes to their bladders.Surgery is the primary treatment for patients with moderate-to-severe symptoms.However,psychological comorbidities after surgery can cause some patients to experience decreased treatment adherence,which in turn affects the recovery of urinary function.Depression and BPH have a high overlap rate in the elderly population.However,the impact of depression on the postoperative recovery from BPH needs to be systematically verified.AIM To help find out what happens in the long-term with pee after surgery for prostate cancer.This will help to create special treatments for people with this problem.METHODS In this investigation,past information was gathered from 756 sufferers of BPH who had undergone surgical procedures at Wuxi Ninth People’s Hospital Affiliated to Soochow University,and the Second Affiliated Hospital of Nanjing Medical University,from January 2021 to January 2025.Patients were divided into two groups based on the presence of depression:Comorbidity(n=65)and noncomorbidity(n=691).The two groups were compared at 6 months and 12 months after surgery in terms of their demographic and clinical characteristics,how well they took their medication,and their urinary function.We used a special type of maths to work out what causes people to take their medicine.We also used a special type of maths to see how depression affects people’s ability to pee.RESULTS Patients with depression and comorbidities showed significantly lower medication adherence self-efficacy,more missed doses and follow-up visits,and poorer health behaviors than those without depression(P<0.05).They also had higher International Prostate Symptom Score and lower Quality of Life scores at 6 and 12 months postoperatively,along with lower maximum flow rate and higher post-void residual urine volume(P<0.05).Improvement in urinary function was less marked in depressed patients.Multivariate analysis identified depression[odds ratio(OR=3.215,95%confidence interval(CI):1.892-5.463)],age≥70 years(OR=2.108,95%CI:1.276-3.482),and primary education or below(OR=1.983,95%CI:1.195-3.294)as independent risk factors for poor adherence.Hamilton Depression Rating Scale scores correlated positively with International Prostate Symptom Score,Quality of Life,and post-void residual urine volume,and negatively with maximum flow rate(P<0.001).CONCLUSION The study found that depression can make it harder to stick to treatment and can also make it take longer to recover from surgery for BPH.The study also found that the more severe the depression,the less likely the patient is to recover well.The findings emphasise the significance of conducting depression screenings at the outset and of implementing comprehensive interventions for BPH patients who also have depression.This approach is intended to enhance adherence to treatment and to ensure the best possible postoperative urinary outcomes.展开更多
Objective:To investigate and analyze the effect of laparoscopic pelvic autonomic nerve-preserving radical resection of rectal cancer on urinary and sexual function.Methods:Cases of laparoscopic radical resection of re...Objective:To investigate and analyze the effect of laparoscopic pelvic autonomic nerve-preserving radical resection of rectal cancer on urinary and sexual function.Methods:Cases of laparoscopic radical resection of rectal cancer in our hospital from April 2018 to April 2023 were selected,and 60 patients who met the requirements were included as research subjects.The patients were divided into an experimental group and a reference group by a double-blind mechanism,with 30 cases in each group.The experimental group underwent laparoscopic pelvic autonomic radical resection,while the reference group underwent ordinary radical resection.The voiding function,urodynamics,sexual function,and blood indexes of the patients of both groups were compared.Results:The total incidence of voiding dysfunction in the experimental group was significantly lower than in the reference group(P0.05);after the operation,the blood indexes of the patients in the experimental group were significantly better than those in the reference group(P<0.05).Conclusion:Laparoscopic pelvic autonomic nerve-preserving radical resection of rectal cancer has lesser effects on urinary and sexual functions.展开更多
Purpose: This study intended to assess the feasibility of an individualized voiding program in Japan aimed at improving the sense of micturition control in older people with functional urinary incontinence. Method: Fo...Purpose: This study intended to assess the feasibility of an individualized voiding program in Japan aimed at improving the sense of micturition control in older people with functional urinary incontinence. Method: Following the interview guide, FGIs were conducted in two groups (4 - 6 participants) consisting of nurses and care workers with more than 5 years of experience as practitioners of urination care. Data were analyzed using a qualitative descriptive approach. Results: We determined that the program purpose is to “enable caregivers to work as a well-coordinated team to humanely facilitate excretion independence in older people, which is essential for living with dignity”, as this confirmed the importance of maintaining the sense of micturition control in older people for their well-being. In the program outline, we extracted the following five categories: 1) setting selection criteria for recipients considering the status of micturition induction, 2) careful collection of information and assessment of lower urinary tract symptoms in older people in case of environmental changes, 3) examination of methods used for assessing lower urinary tract symptoms according to the facility environment, 4) confirmation of the recipient’s micturition habits and request for assistance, and 5) conducting necessary examination for setting the intervention period and evaluation period according to the target condition. The feedback on the program guide was summarized in the statement—specific successful cases help frame and implement the micturition induction plan. Conclusion: We confirmed the feasibility of the micturition induction plan for improving the sense of control in older people with functional urinary incontinence. Upon evaluating the program guide, we deemed that referring to specific successful cases helps frame and implement the micturition induction plan. It is extremely important to verify the effectiveness of the program going forward.展开更多
Background:We investigated potential disparities in health-related quality of life,particularly concerning urinary function,between patients with preserved and those with impaired sexual function after robot-assisted ...Background:We investigated potential disparities in health-related quality of life,particularly concerning urinary function,between patients with preserved and those with impaired sexual function after robot-assisted radical prostatectomy(RARP).Materials and methods:BetweenDecember 2012 and April 2020,704men underwent RARP in our hospital.This study included 155 patients with a preoperative 5-item International Index of Erectile Function(IIEF-5)of≥12 points and an assessable IIEF-5 at 12 months postoperatively.Health-related quality of life was assessed using the 8-item Short-Form Health Survey and Expanded Prostate Cancer Index Composite(EPIC)preoperatively and at 3,6,and 12months postoperatively.A logistic regression analysis andWilcoxon rank sum tests were performed.Results:Patients were grouped according to the median IIEF-5 score 12 months after surgery:those with preserved sexual function(n=71)and those with impaired sexual function(n=84).The mental component summary of the 8-item Short-Form Health Survey was better in the group with preserved sexual function at 6 months postoperatively than in the group with impaired sexual function(p<0.01).In the EPIC,the group with preserved sexual function performed better not only in the sexual domain but also in the urinary domain at all time points comparedwith the groupwith impaired sexual function(p<0.01).In the comparison of the urinary subdomains of the EPIC,there were no significant differences in urinary function or incontinence,but there were significant differences in urinary distress and irritative/obstructive scores(p<0.01).Conclusions:Patients with preserved postoperative sexual function after RARP showed better urinary function than those with impaired sexual function.Hence,preserved sexual function is closely associated with urinary function.展开更多
For recent decades,a considerable amount of^99mTC has been stimulated for diagnosis radiopharmaceuticals because of its physical advantages.The increase in the use of^99mTc makes naturally more chances of internal exp...For recent decades,a considerable amount of^99mTC has been stimulated for diagnosis radiopharmaceuticals because of its physical advantages.The increase in the use of^99mTc makes naturally more chances of internal exposure for not only patients but also medical workers.The patient internal exposure by an intravenous injection has been assessed relatively well with the reports of International Commission on Radiological Protection(ICRP)or Medical Internal Radiation Dose(MIRD).However,there are few studies which can support its accurate assessment for medical worker who treats^99mTc.In spite of the absence of information,the physiological information of each^99mTc-labelled compound for patient,provided by ICRR can be used optionally for worker exposure because the behaviors after uptake to blood are similar for patient and worker.Using the data,in this study,the data for bioassay were given as the intake whole-body retention and urinary excretion function.We selected the two most frequently used^99mTc-labelled compounds based on statistical data;^99mTc-phosphonate,pertechnetate.The data of the Human Alimentary Tract Model(HATM,publication 100)and the revised Human Respiratory Tract Model(revised HRTM,OIR)were used for compartment models which depict the physiological behavior in body after intake.In case of^99mTc-phosphonate,we adopted the systemic model for patient intake described in ICRP publication 53 based on the assumption that the behaviors after uptake to blood are similar for patient and worker.On the other hand,recent updated systemic model in OIR report could be directly adopted for pertechnetate.We used Birchall's algorithm for calculation and developed the module which could calculate the retention amounts in each compartment at given time by MATLAB.In addition,we fitted the functions as sum of exponential terms using ORIGIN and the fitting coefficients were provided.We also could calculate the committed dose coefficients for each compound using SAF values for photons provided by Cristy and Eckerman.The results in this study will be useful to estimate the intake and effective dose for medical field.展开更多
基金Supported by Wuxi Municipal Health Commission General Project,No.M202459.
摘要BACKGROUND Benign prostatic hyperplasia(BPH)-that’s BPH,by the way-is a pretty serious problem for older guys when it comes to their bladders.Surgery is the primary treatment for patients with moderate-to-severe symptoms.However,psychological comorbidities after surgery can cause some patients to experience decreased treatment adherence,which in turn affects the recovery of urinary function.Depression and BPH have a high overlap rate in the elderly population.However,the impact of depression on the postoperative recovery from BPH needs to be systematically verified.AIM To help find out what happens in the long-term with pee after surgery for prostate cancer.This will help to create special treatments for people with this problem.METHODS In this investigation,past information was gathered from 756 sufferers of BPH who had undergone surgical procedures at Wuxi Ninth People’s Hospital Affiliated to Soochow University,and the Second Affiliated Hospital of Nanjing Medical University,from January 2021 to January 2025.Patients were divided into two groups based on the presence of depression:Comorbidity(n=65)and noncomorbidity(n=691).The two groups were compared at 6 months and 12 months after surgery in terms of their demographic and clinical characteristics,how well they took their medication,and their urinary function.We used a special type of maths to work out what causes people to take their medicine.We also used a special type of maths to see how depression affects people’s ability to pee.RESULTS Patients with depression and comorbidities showed significantly lower medication adherence self-efficacy,more missed doses and follow-up visits,and poorer health behaviors than those without depression(P<0.05).They also had higher International Prostate Symptom Score and lower Quality of Life scores at 6 and 12 months postoperatively,along with lower maximum flow rate and higher post-void residual urine volume(P<0.05).Improvement in urinary function was less marked in depressed patients.Multivariate analysis identified depression[odds ratio(OR=3.215,95%confidence interval(CI):1.892-5.463)],age≥70 years(OR=2.108,95%CI:1.276-3.482),and primary education or below(OR=1.983,95%CI:1.195-3.294)as independent risk factors for poor adherence.Hamilton Depression Rating Scale scores correlated positively with International Prostate Symptom Score,Quality of Life,and post-void residual urine volume,and negatively with maximum flow rate(P<0.001).CONCLUSION The study found that depression can make it harder to stick to treatment and can also make it take longer to recover from surgery for BPH.The study also found that the more severe the depression,the less likely the patient is to recover well.The findings emphasise the significance of conducting depression screenings at the outset and of implementing comprehensive interventions for BPH patients who also have depression.This approach is intended to enhance adherence to treatment and to ensure the best possible postoperative urinary outcomes.
摘要Objective:To investigate and analyze the effect of laparoscopic pelvic autonomic nerve-preserving radical resection of rectal cancer on urinary and sexual function.Methods:Cases of laparoscopic radical resection of rectal cancer in our hospital from April 2018 to April 2023 were selected,and 60 patients who met the requirements were included as research subjects.The patients were divided into an experimental group and a reference group by a double-blind mechanism,with 30 cases in each group.The experimental group underwent laparoscopic pelvic autonomic radical resection,while the reference group underwent ordinary radical resection.The voiding function,urodynamics,sexual function,and blood indexes of the patients of both groups were compared.Results:The total incidence of voiding dysfunction in the experimental group was significantly lower than in the reference group(P0.05);after the operation,the blood indexes of the patients in the experimental group were significantly better than those in the reference group(P<0.05).Conclusion:Laparoscopic pelvic autonomic nerve-preserving radical resection of rectal cancer has lesser effects on urinary and sexual functions.
摘要Purpose: This study intended to assess the feasibility of an individualized voiding program in Japan aimed at improving the sense of micturition control in older people with functional urinary incontinence. Method: Following the interview guide, FGIs were conducted in two groups (4 - 6 participants) consisting of nurses and care workers with more than 5 years of experience as practitioners of urination care. Data were analyzed using a qualitative descriptive approach. Results: We determined that the program purpose is to “enable caregivers to work as a well-coordinated team to humanely facilitate excretion independence in older people, which is essential for living with dignity”, as this confirmed the importance of maintaining the sense of micturition control in older people for their well-being. In the program outline, we extracted the following five categories: 1) setting selection criteria for recipients considering the status of micturition induction, 2) careful collection of information and assessment of lower urinary tract symptoms in older people in case of environmental changes, 3) examination of methods used for assessing lower urinary tract symptoms according to the facility environment, 4) confirmation of the recipient’s micturition habits and request for assistance, and 5) conducting necessary examination for setting the intervention period and evaluation period according to the target condition. The feedback on the program guide was summarized in the statement—specific successful cases help frame and implement the micturition induction plan. Conclusion: We confirmed the feasibility of the micturition induction plan for improving the sense of control in older people with functional urinary incontinence. Upon evaluating the program guide, we deemed that referring to specific successful cases helps frame and implement the micturition induction plan. It is extremely important to verify the effectiveness of the program going forward.
摘要Background:We investigated potential disparities in health-related quality of life,particularly concerning urinary function,between patients with preserved and those with impaired sexual function after robot-assisted radical prostatectomy(RARP).Materials and methods:BetweenDecember 2012 and April 2020,704men underwent RARP in our hospital.This study included 155 patients with a preoperative 5-item International Index of Erectile Function(IIEF-5)of≥12 points and an assessable IIEF-5 at 12 months postoperatively.Health-related quality of life was assessed using the 8-item Short-Form Health Survey and Expanded Prostate Cancer Index Composite(EPIC)preoperatively and at 3,6,and 12months postoperatively.A logistic regression analysis andWilcoxon rank sum tests were performed.Results:Patients were grouped according to the median IIEF-5 score 12 months after surgery:those with preserved sexual function(n=71)and those with impaired sexual function(n=84).The mental component summary of the 8-item Short-Form Health Survey was better in the group with preserved sexual function at 6 months postoperatively than in the group with impaired sexual function(p<0.01).In the EPIC,the group with preserved sexual function performed better not only in the sexual domain but also in the urinary domain at all time points comparedwith the groupwith impaired sexual function(p<0.01).In the comparison of the urinary subdomains of the EPIC,there were no significant differences in urinary function or incontinence,but there were significant differences in urinary distress and irritative/obstructive scores(p<0.01).Conclusions:Patients with preserved postoperative sexual function after RARP showed better urinary function than those with impaired sexual function.Hence,preserved sexual function is closely associated with urinary function.
摘要For recent decades,a considerable amount of^99mTC has been stimulated for diagnosis radiopharmaceuticals because of its physical advantages.The increase in the use of^99mTc makes naturally more chances of internal exposure for not only patients but also medical workers.The patient internal exposure by an intravenous injection has been assessed relatively well with the reports of International Commission on Radiological Protection(ICRP)or Medical Internal Radiation Dose(MIRD).However,there are few studies which can support its accurate assessment for medical worker who treats^99mTc.In spite of the absence of information,the physiological information of each^99mTc-labelled compound for patient,provided by ICRR can be used optionally for worker exposure because the behaviors after uptake to blood are similar for patient and worker.Using the data,in this study,the data for bioassay were given as the intake whole-body retention and urinary excretion function.We selected the two most frequently used^99mTc-labelled compounds based on statistical data;^99mTc-phosphonate,pertechnetate.The data of the Human Alimentary Tract Model(HATM,publication 100)and the revised Human Respiratory Tract Model(revised HRTM,OIR)were used for compartment models which depict the physiological behavior in body after intake.In case of^99mTc-phosphonate,we adopted the systemic model for patient intake described in ICRP publication 53 based on the assumption that the behaviors after uptake to blood are similar for patient and worker.On the other hand,recent updated systemic model in OIR report could be directly adopted for pertechnetate.We used Birchall's algorithm for calculation and developed the module which could calculate the retention amounts in each compartment at given time by MATLAB.In addition,we fitted the functions as sum of exponential terms using ORIGIN and the fitting coefficients were provided.We also could calculate the committed dose coefficients for each compound using SAF values for photons provided by Cristy and Eckerman.The results in this study will be useful to estimate the intake and effective dose for medical field.